Syndra - League of Legends Champion
Win Rate
49.8%
Pick Rate
2.3%

Syndravs Annie

CMage
Patch26.4
Matches1,089,240
LaneAll Lanes
TierAll Tiers
Last UpdatedFeb 28, 2026
MethodologyData Methodology

Syndra vs Annie is a decisive matchup in LoL patch 26.4. Syndra wins with a 57.6% win rate (+15.2%) over Annie based on 67 games. Syndra holds the advantage in both the early and late game. Below you'll find the best Syndra build, runes, laning stats, and strategies for the Syndra vs Annie matchup.

Syndra Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Syndra performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Annie - 57.6% win rateAnnie(57.6%)
Syndra - 57.6% win rate in this matchup
Syndra
57.6% WR
VS
Annie vs Syndra matchup - 42.4% win rate
Annie
42.4% WR

Who Wins the Syndra vs Annie Matchup?

Syndra wins the Syndra vs Annie matchup
Winner
Syndra
Matches: 67
57.6%
Win Rate
42.4%
7.2
CS / min
5.9
911
DMG / min
780
13,293
Gold / game
11,066
83
Heal / min
68
310
DMG Mitigated / min
410
1.4
CC / min
0.8
61.3%
Early Game WR
38.7%
54.3%
Late Game WR
45.7%

Syndra vs Annie Matchup Summary

The Syndra vs Annie matchup is a decisive matchup in League of Legends ranked play. Based on 67 recent matches analyzed, Syndra wins with a 57.6% win rate compared to Annie's 42.4%, giving Syndra a 15.2 percentage point advantage. Syndra dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Annie players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Syndra leads by 0.6s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Syndra players can confidently pick into Annie and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Annie away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Syndra vs Annie Laning Phase Breakdown

Syndra wins the laning phase against Annie in League of Legends

Syndra is favored during the laning phase against Annie, winning 4 out of 5 key stat categories. Syndra holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.

Farming
7.2Syndra
5.9Annie
Syndra significantly out-farms Annie by 1.2 CS per minute, accumulating an estimated 18 CS lead by mid game. This substantial farming gap gives Syndra a major gold advantage and earlier item completions. Annie players should prioritize wave management techniques like freezing near tower and using abilities efficiently to minimize the deficit.
Damage
911Syndra
780Annie
Syndra heavily out-damages Annie by 131 DMG/min, dominating both short trades and all-in fights. Annie should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Syndra's sustained damage advantage take over.
Economy
13,293Syndra
11,066Annie
Syndra generates a commanding 2,227 more gold per game than Annie. This substantial economic advantage means Syndra consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Annie should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
1.4Syndra
0.8Annie
Syndra provides 0.6 seconds more crowd control per minute than Annie, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Syndra coordinate with their jungler and control the pace of skirmishes.
Sustain
393Syndra
477Annie
Annie heals and mitigates 84 more damage per minute than Syndra, providing moderate extra durability. This sustain edge allows Annie to stay in lane longer between recalls and gradually win extended wars of attrition. Consider building early grievous wounds if playing Syndra.

Best Syndra Build Against Annie

Spellslinger's Shoes is the optimal boots choice against Annie, providing the mobility and stats Syndra needs most in this matchup. The top-performing core items for Syndra against Annie are Luden's Echo, Shadowflame and Rabadon's Deathcap. This combination gives Syndra an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 4 games — well above average and making it the top item path against Annie. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Syndra vs Annie matchup.

Early Game vs Late Game

Early Game
Syndra
61.3%
+22.6% advantage
Syndra early game win rateSyndra61.3%
Annie early game win rateAnnie38.7%
Late Game
Syndra
54.3%
+8.6% advantage
Syndra late game win rateSyndra54.3%
Annie late game win rateAnnie45.7%

Syndra dominates the early game (first 15 minutes) with a commanding 61.3% win rate — a 22.6 percentage point lead over Annie. This lopsided early game means Syndra can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Syndra is far superior in the late game (25+ minutes), boasting a 54.3% win rate — 8.6 points above Annie. Extended games heavily favor Syndra, whose kit and scaling make them a dominant force in team fights and objective control.

Syndra holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Annie players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Syndra Runes Against Annie

Domination rune tree - Syndra primary runes vs AnnieDomination
Electrocute - best Syndra rune vs AnnieTaste of Blood - best Syndra rune vs AnnieGrisly Mementos - best Syndra rune vs AnnieUltimate Hunter - best Syndra rune vs Annie
Sorcery rune tree - Syndra secondary runes vs AnnieSorcery
Manaflow Band - best Syndra rune vs AnnieTranscendence - best Syndra rune vs Annie
85.7% WR

Running Domination primary with Sorcery secondary allows Syndra to press their advantage against Annie, amplifying the strengths that make this a favorable matchup.


Syndra matchup data for League of Legends patch 26.4. The table below shows Syndra's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Syndra build, runes, laning stats, and early vs late game analysis for that specific matchup.

Syndra matchup win rates and stats in League of Legends patch 26.4
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
48.43%3867.188612,53447.1%49.5%
47.30%2237.083812,27335.8%55.9%
48.91%1847.285813,08650.7%47.8%
52.73%1666.991913,27340.4%59.3%
51.61%1577.489613,01757.8%47.3%
40.88%1376.872811,88337.5%43.8%
46.56%1326.878112,10739.7%52.0%
46.92%1317.182712,63650.0%44.6%
58.02%1316.885112,27353.1%62.7%
53.33%1217.295812,90454.9%52.2%
59.50%1216.987312,52448.0%67.6%
43.22%1187.295912,74242.3%43.9%
53.15%1126.987312,64654.2%52.4%
52.38%1057.188312,87459.1%47.5%
53.00%1006.779811,59355.0%51.7%
45.92%987.499313,22454.4%38.5%
52.58%987.094313,13660.5%47.5%
42.71%977.284512,45743.5%42.0%
52.13%946.879612,11265.2%39.6%
56.38%946.894712,71350.0%60.3%
48.91%927.286413,06448.6%49.1%
47.78%907.186312,63250.0%46.1%
52.38%846.891613,27347.2%56.3%
43.24%746.781211,70535.1%51.4%
58.90%737.597612,76057.5%60.6%
48.57%706.880112,75938.5%54.5%
50.75%687.073012,22346.9%54.3%
57.58%677.291113,29361.3%54.3%
51.56%657.086312,67948.5%54.8%
42.62%627.596011,01050.0%32.0%
51.67%607.197212,99868.2%42.1%
55.17%597.31,01413,27556.5%54.3%
47.06%517.189912,86266.7%33.3%
44.90%507.086112,72347.6%42.9%
44.44%456.797012,21654.5%34.8%
41.86%447.395713,60457.1%34.5%
67.44%436.789911,24363.6%71.4%
47.50%406.894411,55447.6%47.4%
62.86%356.790712,32956.3%68.4%
37.14%356.774511,81150.0%30.4%
61.76%347.390612,39875.0%50.0%
40.63%327.61,09313,21833.3%47.1%
37.93%306.81,01212,87736.4%38.9%
51.72%297.189513,37455.6%50.0%
53.57%286.894512,03440.0%69.2%
60.71%286.782713,36377.8%52.6%
55.56%277.099613,84533.3%61.9%
65.38%276.681311,75750.0%78.6%
57.69%267.198314,06741.7%71.4%
54.17%256.890013,88862.5%50.0%
41.67%247.188213,81144.4%40.0%
39.13%236.385611,79233.3%42.9%
38.10%227.286113,84150.0%30.8%
42.86%217.184614,32641.7%44.4%
42.86%217.692913,60337.5%46.1%
42.86%216.886714,08057.1%35.7%
58.82%177.51,05814,60442.9%70.0%
43.75%166.31,07113,32050.0%37.5%
33.33%156.31,00615,131100.0%23.1%
66.67%157.184914,56066.7%66.7%
46.67%157.185212,09633.3%66.7%
66.67%156.698214,68383.3%55.6%
46.67%157.41,02710,93444.4%50.0%
61.54%136.784311,51840.0%75.0%
84.62%137.795015,15850.0%90.9%
46.15%137.199813,67625.0%80.0%
46.15%136.789714,02333.3%50.0%
75.00%126.378412,09360.0%85.7%
50.00%126.793714,34933.3%55.6%
63.64%117.298114,51375.0%57.1%
27.27%116.58099,85033.3%20.0%
66.67%107.784415,223100.0%50.0%
50.00%107.093011,27960.0%40.0%
50.00%107.48289,65557.1%33.3%
62.50%97.076810,19675.0%50.0%
44.44%95.495413,95066.7%33.3%
66.67%96.188214,660100.0%57.1%
37.50%86.774411,8370.0%50.0%
37.50%87.599913,39433.3%40.0%
42.86%75.885810,46840.0%50.0%
28.57%77.788713,2500.0%50.0%
71.43%77.378811,36380.0%50.0%
28.57%77.41,08212,17825.0%33.3%
42.86%76.496812,52850.0%40.0%
57.14%75.979012,08866.7%50.0%
50.00%66.97149,39550.0%50.0%
83.33%67.11,04913,28266.7%100.0%
66.67%67.087812,28066.7%66.7%
83.33%67.376412,28766.7%100.0%
16.67%67.388511,55325.0%0.0%
50.00%67.187315,15750.0%50.0%
60.00%53.183510,72066.7%50.0%
100.00%57.495114,637100.0%100.0%
20.00%57.07269,2530.0%100.0%
20.00%51.78219,15033.3%0.0%
20.00%52.982611,5410.0%20.0%
60.00%56.075113,04933.3%100.0%
60.00%57.31,03310,82150.0%100.0%
60.00%56.880610,3780.0%100.0%
100.00%57.41,20515,337100.0%100.0%
40.00%56.61,02213,11666.7%0.0%
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Syndra vs Annie - Frequently Asked Questions

How does Syndra do against Annie in League of Legends?

Syndra wins the Syndra vs Annie matchup with a 57.6% win rate compared to Annie's 42.4%, a 15.2 percentage point difference. This data is based on 67 recent ranked games in patch 26.4.

How does Syndra do against Annie in the early game?

In the early game, Syndra has the advantage against Annie with a 61.3% win rate versus 38.7%. Syndra players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Syndra do against Annie in the late game?

In the late game, Syndra takes over the Syndra vs Annie matchup with a 54.3% win rate compared to 45.7%. Syndra scales better into team fights and objective contests after 25 minutes.

Who wins the Syndra vs Annie matchup?

Syndra wins the matchup against Annie with a 57.6% win rate in League of Legends patch 26.4. The 15.2 percentage point advantage means Syndra is significantly favored in this lane matchup based on 67 games analyzed.

What is the best Syndra build against Annie?

The best Syndra build against Annie includes Luden's Echo, Shadowflame, Rabadon's Deathcap with Spellslinger's Shoes. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Syndra runes against Annie?

The best Syndra runes against Annie use the Domination primary tree with Sorcery secondary. This rune setup achieves a 85.7% win rate in the Syndra vs Annie matchup. See the full rune breakdown in the matchup comparison above.

Does Syndra counter Annie?

Yes, Syndra has a favorable matchup against Annie with a 57.6% win rate. Syndra strongly counters Annie in lane based on current patch 26.4 data.

How do I play Syndra against Annie?

When playing Syndra against Annie, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.