- Win Rate
- 51.2%
- Pick Rate
- 3.4%
- Ban Rate
- 12.3%
Twitch vs Vayne
- Patch
- 26.21
- Games
- 6,883
- Lane
- All Lanes
- Tier
- All Tiers
- Last Updated
- Nov 3, 2026 UTC
- Author
- Dakota Chinnick
- Methodology
- Data Methodology
Twitch vs Vayne is a moderate matchup in LoL patch 26.21. Vayne wins with a 51.8% win rate (+3.6%) over Twitch based on 253 games. Twitch wins the early laning phase while Vayne scales better into the late game. Below you'll find the best Twitch build, runes, laning stats, and strategies for the Twitch vs Vayne matchup.
Twitch Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Twitch performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who wins Twitch vs Vayne?
Twitch wins 48.0% of these games. With this many games the true rate is most likely between 41.8% and 54.2% (95% range).
- Expected
- 52.0% From both champions' overall Bot win rates
- Matchup effect
- −4.0 pts Observed minus expected
- Sample
- 244 games Lane: Bot
- vs patch 26.20
- +1.5 pts Within normal patch-to-patch noise
Lane: Bot · Ranked Solo/Duo & Flex · North America server · All ranks · Patch 26.21 · Oct 27 – Nov 3
Key takeaways
- Current data slightly favors Vayne, but the sample is too limited for a strong conclusion: Twitch wins 48.0% of 244 games (95% range 41.8–54.2%).
- Both champions' overall Bot win rates predict 52.0% for Twitch; the result is within the margin of error of that, so this matchup mostly reflects the two champions' general strength.
- Neither side reliably wins the lane: the average gold difference at 15 minutes is 181, within the margin of error (243 games).
How we calculate this
Games: ranked Solo/Duo and Flex games on the North America server from the patch shown. Remakes (games under 5 minutes) are excluded.
A game only counts when Twitch and Vayne played the same position on opposite teams, so roaming, lane swaps within a team or a champion merely being in the same game never count as this matchup.
The 95% range is a Wilson score interval. Confidence comes from how wide that range is: within ±3 points is very high, ±5 high, ±8 moderate, anything wider low. Below 20 games a matchup is not classified at all.
Expected win rate combines both champions’ win rates in this lane (same games and filters) with the log5 formula: E = A(1−B) / (A(1−B) + B(1−A)). Matchup effect = observed − expected.
"What changes" compares Twitch's choices in this matchup with the same champion's other games in the same lane, and lists a change only when it is at least 3 points and statistically significant (two-proportion z-test, |z| ≥ 2, 20+ games).
Results are not split by rank: the sample per rank is too small for honest per-rank matchup numbers.
Twitch vs Vayne Laning Stats
At 15 minutes
Whole-game averages
Twitch vs Vayne Win Rate by Game Length
Twitch's win rate against Vayne by game length. The dot is the win rate, the bar its 95% range and the dashed line the champion's usual win rate at that length. Lengths with fewer than 25 games are left blank.
No game length stands out: Twitch's results against Vayne in short and long games are within the margin of error of each other.
Twitch vs Vayne Power Spikes
Who is ahead at each stage, measured from these games. A stage reads "Even" when the difference is inside the margin of error, and "Insufficient data" when there are too few games to tell.
- Lane (15 min)EvenTwitch gold at 15: +181
- First itemTwitchTwitch: 11.8 min · Vayne: 13.1 min
- Games under 20 minInsufficient data
- 20–30 min gamesEvenTwitch wins 49.5% of 101 games
- 30+ min gamesEvenTwitch wins 45.0% of 129 games
What Twitch Changes Against Vayne
Twitch players don't meaningfully change their setup against Vayne: no item, rune, spell or skill order differs by 3 points or more beyond the margin of error. The usual build applies.
Best Twitch Build vs Vayne
Usual Twitch build (Bot)
76.2% win rate · 42 games
Against Vayne
Not enough matchup-specific build data: only 19 of 190 Twitch games against Vayne carried a complete build, which is too few to recommend an item path from. Use Twitch's standard build instead.
- Twitch usually completes The Collector first, at 11.8 min (median of 169 games).
- Vayne usually completes Blade of The Ruined King first, at 13.1 min (median of 128 games).
- Skill priority: E > Q > W — the same as usual.
Builds are ranked by the lower edge of their win rate range, not the raw win rate, so a build seen in a handful of wins never outranks a proven one.
Best Twitch Runes vs Vayne
Usual Twitch runes (Bot)
Lethal Tempo
53.3% win rate · 1,331 games
Against Vayne
Lethal Tempo50.0% win rate · 62 games
Plan your Twitch draft in Draft Lab
Draft Lab lays out both teams lane by lane with live matchup win rates, damage profiles and game-phase lean, and suggests picks and bans from current meta data.
- Full 5v5 draft board
- Lane matchup win rates
- Pick and ban suggestions
Twitch matchup data for League of Legends patch 26.21. The table below shows Twitch's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Twitch build, runes, laning stats, and early vs late game analysis for that specific matchup.
Other Twitch Matchups
Hardest for Twitch
Easiest for Twitch
Win rate and games for each matchup. Lists are ranked by the edge of the 95% range so small samples cannot top them; matchups with at least 50 games only.
Help us maintain accuracy! If you notice incorrect stats, missing data, or any issues, your feedback directly improves the quality of our data for the entire community.
Twitch vs Vayne FAQ - Patch 26.21
Who wins Twitch vs Vayne?
Current data slightly favors Vayne, but the sample is too limited for a strong conclusion: Twitch wins 48.0% of 244 games (95% range 41.8–54.2%).
What is Twitch's win rate against Vayne?
Twitch wins 48.0% of 244 Bot games against Vayne on patch 26.21 (95% range 41.8–54.2%). Based on both champions' overall Bot win rates, 52.0% would be expected.
Does Twitch counter Vayne?
Not clearly. Twitch wins 48.0% of 244 games against Vayne, and the 95% range (41.8–54.2%) includes 50%, so neither champion reliably counters the other on current data.
Who wins lane, Twitch or Vayne?
Neither side reliably wins the lane: the average gold difference at 15 minutes is 181, within the margin of error (243 games).
Does Twitch outscale Vayne?
Not measurably: Twitch's win rate against Vayne in games of 25 minutes or less and in longer games is within the margin of error of each other.
When is Vayne strongest against Twitch?
On current data there is no stage of the game where Vayne is ahead of Twitch beyond the margin of error.
What should Twitch build against Vayne?
There are not enough games for a matchup-specific core, so use Twitch's usual Bot core: Runaan's Hurricane, Bloodthirster, Lord Dominik's Regards.
What runes should Twitch use against Vayne?
Lethal Tempo with Precision and Domination — 50.0% over 62 games against Vayne.