- Win Rate
- 49.8%
- Pick Rate
- 4.2%
- Ban Rate
- 5.0%
Vayne vs Twitch
- Patch
- 26.21
- Games
- 8,410
- Lane
- All Lanes
- Tier
- All Tiers
- Last Updated
- Nov 3, 2026 UTC
- Author
- Dakota Chinnick
- Methodology
- Data Methodology
Vayne vs Twitch is a moderate matchup in LoL patch 26.21. Vayne wins with a 51.8% win rate (+3.6%) over Twitch based on 253 games. Twitch wins the early laning phase while Vayne scales better into the late game. Below you'll find the best Vayne build, runes, laning stats, and strategies for the Vayne vs Twitch matchup.
Vayne Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Vayne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who wins Vayne vs Twitch?
Vayne wins 52.0% of these games. With this many games the true rate is most likely between 45.8% and 58.2% (95% range).
- Expected
- 48.0% From both champions' overall Bot win rates
- Matchup effect
- +4.0 pts Observed minus expected
- Sample
- 244 games Lane: Bot
- vs patch 26.20
- −1.5 pts Within normal patch-to-patch noise
Lane: Bot · Ranked Solo/Duo & Flex · North America server · All ranks · Patch 26.21 · Oct 27 – Nov 3
Key takeaways
- Current data slightly favors Vayne, but the sample is too limited for a strong conclusion: Vayne wins 52.0% of 244 games (95% range 45.8–58.2%).
- Both champions' overall Bot win rates predict 48.0% for Vayne; the result is within the margin of error of that, so this matchup mostly reflects the two champions' general strength.
- Neither side reliably wins the lane: the average gold difference at 15 minutes is 181, within the margin of error (243 games).
- Vayne players pick Essence Reaver far more often against Twitch: 12.6% of their other Bot games, 18.4% here.
How we calculate this
Games: ranked Solo/Duo and Flex games on the North America server from the patch shown. Remakes (games under 5 minutes) are excluded.
A game only counts when Vayne and Twitch played the same position on opposite teams, so roaming, lane swaps within a team or a champion merely being in the same game never count as this matchup.
The 95% range is a Wilson score interval. Confidence comes from how wide that range is: within ±3 points is very high, ±5 high, ±8 moderate, anything wider low. Below 20 games a matchup is not classified at all.
Expected win rate combines both champions’ win rates in this lane (same games and filters) with the log5 formula: E = A(1−B) / (A(1−B) + B(1−A)). Matchup effect = observed − expected.
"What changes" compares Vayne's choices in this matchup with the same champion's other games in the same lane, and lists a change only when it is at least 3 points and statistically significant (two-proportion z-test, |z| ≥ 2, 20+ games).
Results are not split by rank: the sample per rank is too small for honest per-rank matchup numbers.
Vayne vs Twitch Laning Stats
At 15 minutes
Whole-game averages
Vayne vs Twitch Win Rate by Game Length
Vayne's win rate against Twitch by game length. The dot is the win rate, the bar its 95% range and the dashed line the champion's usual win rate at that length. Lengths with fewer than 25 games are left blank.
No game length stands out: Vayne's results against Twitch in short and long games are within the margin of error of each other.
Vayne vs Twitch Power Spikes
Who is ahead at each stage, measured from these games. A stage reads "Even" when the difference is inside the margin of error, and "Insufficient data" when there are too few games to tell.
- Lane (15 min)EvenVayne gold at 15: −181
- First itemTwitchVayne: 13.1 min · Twitch: 11.8 min
- Games under 20 minInsufficient data
- 20–30 min gamesEvenVayne wins 50.5% of 101 games
- 30+ min gamesEvenVayne wins 55.0% of 129 games
What Vayne Changes Against Twitch
Choices Vayne players make noticeably more or less often in this matchup than in their other Bot games.
Essence ReaverItemUsually12.6%vs Twitch18.4%+5.8 pts48.9% WR here
Best Vayne Build vs Twitch
Usual Vayne build (Bot)
58.5% win rate · 410 games
Against Twitch
57.6% win rate · 33 games
Limited sample: 33 of 174 games finished this exact core, so treat it as an observation rather than a recommendation.
- Vayne usually completes Blade of The Ruined King first, at 13.1 min (median of 128 games).
- Twitch usually completes The Collector first, at 11.8 min (median of 169 games).
- Skill priority: Q > W > E — the same as usual.
Builds are ranked by the lower edge of their win rate range, not the raw win rate, so a build seen in a handful of wins never outranks a proven one.
Best Vayne Runes vs Twitch
Usual Vayne runes (Bot)
Lethal Tempo
50.7% win rate · 3,727 games
Against Twitch
Lethal Tempo56.1% win rate · 132 games
Plan your Vayne draft in Draft Lab
Draft Lab lays out both teams lane by lane with live matchup win rates, damage profiles and game-phase lean, and suggests picks and bans from current meta data.
- Full 5v5 draft board
- Lane matchup win rates
- Pick and ban suggestions
Vayne matchup data for League of Legends patch 26.21. The table below shows Vayne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vayne build, runes, laning stats, and early vs late game analysis for that specific matchup.
Other Vayne Matchups
Hardest for Vayne
Easiest for Vayne
Win rate and games for each matchup. Lists are ranked by the edge of the 95% range so small samples cannot top them; matchups with at least 50 games only.
Help us maintain accuracy! If you notice incorrect stats, missing data, or any issues, your feedback directly improves the quality of our data for the entire community.
Vayne vs Twitch FAQ - Patch 26.21
Who wins Vayne vs Twitch?
Current data slightly favors Vayne, but the sample is too limited for a strong conclusion: Vayne wins 52.0% of 244 games (95% range 45.8–58.2%).
What is Vayne's win rate against Twitch?
Vayne wins 52.0% of 244 Bot games against Twitch on patch 26.21 (95% range 45.8–58.2%). Based on both champions' overall Bot win rates, 48.0% would be expected.
Does Vayne counter Twitch?
Not clearly. Vayne wins 52.0% of 244 games against Twitch, and the 95% range (45.8–58.2%) includes 50%, so neither champion reliably counters the other on current data.
Who wins lane, Vayne or Twitch?
Neither side reliably wins the lane: the average gold difference at 15 minutes is 181, within the margin of error (243 games).
Does Vayne outscale Twitch?
Not measurably: Vayne's win rate against Twitch in games of 25 minutes or less and in longer games is within the margin of error of each other.
When is Twitch strongest against Vayne?
Twitch is measurably ahead in: First item.
What should Vayne build against Twitch?
The most successful Vayne core against Twitch is Terminus, Blade of The Ruined King, Guinsoo's Rageblade (57.6% over 33 games). The biggest change against Twitch: Essence Reaver (12.6% usually, 18.4% here).
What runes should Vayne use against Twitch?
Lethal Tempo with Precision and Resolve — 56.1% over 132 games against Twitch.