Vayne - League of Legends Champion
Win Rate
49.2%
Pick Rate
4.8%

Vaynevs Kalista

DMarksmanAssassin
Patch26.14
Matches226,800
LaneAll Lanes
TierAll Tiers
Last UpdatedJul 21, 2026
MethodologyData Methodology

Vayne vs Kalista is a decisive matchup in LoL patch 26.14. Kalista wins with a 57.1% win rate (+14.3%) over Vayne based on 7 games. Kalista wins the early laning phase while Vayne scales better into the late game. Below you'll find the best Vayne build, runes, laning stats, and strategies for the Vayne vs Kalista matchup.

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Vayne Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Vayne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Vayne - 42.9% win rate in this matchup
Vayne
42.9% WR
VS
Kalista vs Vayne matchup - 57.1% win rate
Kalista
57.1% WR

Who Wins the Vayne vs Kalista Matchup?

Kalista wins the Vayne vs Kalista matchup
Winner
Kalista
Matches: 7
42.9%
Win Rate
57.1%
5.8
CS / min
6.6
905
DMG / min
833
9,654
Gold / game
12,008
200
Heal / min
210
484
DMG Mitigated / min
440
0.4
CC / min
0.5
40.0%
Early Game WR
60.0%
50.0%
Late Game WR
50.0%

Vayne vs Kalista Matchup Summary

The Vayne vs Kalista matchup is a decisive matchup in League of Legends ranked play. Based on 7 recent matches analyzed, Kalista wins with a 57.1% win rate compared to Vayne's 42.9%, giving Kalista a 14.3 percentage point advantage. Game phase dynamics play a critical role here: Kalista controls the early laning stage, but Vayne outscales as the game goes longer. The matchup shifts dramatically depending on game length — Kalista needs to press advantages before Vayne reaches their power spikes, while Vayne should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Kalista leads by 0.2s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Kalista has a strong advantage in this matchup. Vayne players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Kalista overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Vayne vs Kalista Laning Phase Breakdown

Kalista wins the laning phase against Vayne in League of Legends

Kalista is favored during the laning phase against Vayne, winning 3 out of 5 key stat categories. Kalista holds advantages in farming, gold income and crowd control, making them the stronger laner in this matchup.

Farming
5.8Vayne
6.6Kalista
Kalista significantly out-farms Vayne by 0.8 CS per minute, accumulating an estimated 12 CS lead by mid game. This substantial farming gap gives Kalista a major gold advantage and earlier item completions. Vayne players should prioritize wave management techniques like freezing near tower and using abilities efficiently to minimize the deficit.
Damage
905Vayne
833Kalista
Vayne deals 71 more champion damage per minute than Kalista. While noticeable in extended trades, this gap can be offset by Kalista choosing favorable fight windows, such as engaging when Vayne's key abilities are on cooldown or trading immediately after dodging a skillshot.
Economy
9,654Vayne
12,008Kalista
Kalista generates a commanding 2,354 more gold per game than Vayne. This substantial economic advantage means Kalista consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Vayne should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.4Vayne
0.5Kalista
Both Vayne and Kalista provide similar amounts of crowd control (0.2s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
684Vayne
650Kalista
Vayne and Kalista have comparable sustain profiles, with only 34 HP/min separating their healing and damage mitigation. Neither champion can out-attrition the other in lane, so trades will be decided by burst potential and ability usage rather than sustain.

Early Game vs Late Game

Early Game
Kalista
60.0%
+20.0% advantage
Vayne early game win rateVayne40.0%
Kalista early game win rateKalista60.0%
Late Game
Vayne
50.0%
+0.0% advantage
Vayne late game win rateVayne50.0%
Kalista late game win rateKalista50.0%

Kalista dominates the early game (first 15 minutes) with a commanding 60.0% win rate — a 20.0 percentage point lead over Vayne. This lopsided early game means Kalista can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Late game (25+ minutes) is equally balanced, with Vayne at 50.0% win rate — only 0.0 points ahead of Kalista. Team fight execution and macro play determine the winner at this stage, not champion matchup advantage.

The power dynamics shift as the game progresses — Kalista has the edge early, but Vayne gradually takes over. However, the margins are slim enough that either champion can win at any stage with the right plays. Focus on taking advantages when you have them rather than waiting for a specific game phase.

Best Vayne Runes Against Kalista

Precision rune tree - Vayne primary runes vs KalistaPrecision
Lethal Tempo - best Vayne rune vs KalistaTriumph - best Vayne rune vs KalistaLegend: Alacrity - best Vayne rune vs KalistaCoup de Grace - best Vayne rune vs Kalista
Resolve rune tree - Vayne secondary runes vs KalistaResolve
Conditioning - best Vayne rune vs KalistaOvergrowth - best Vayne rune vs Kalista
0.0% WR

The Precision and Resolve rune setup gives Vayne the best tools to compete against Kalista in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Vayne matchup data for League of Legends patch 26.14. The table below shows Vayne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vayne build, runes, laning stats, and early vs late game analysis for that specific matchup.

Vayne matchup win rates and stats in League of Legends patch 26.14
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
52.41%1665.887913,17044.4%56.3%
46.27%1346.183513,57539.5%49.0%
56.06%1325.987913,82455.3%56.5%
44.27%1316.285112,50645.6%43.2%
55.91%936.287711,72645.6%66.0%
40.48%846.176912,13323.3%50.0%
54.29%706.394613,79337.5%63.0%
37.70%616.384913,09931.6%40.5%
55.00%606.280012,83058.8%53.5%
54.17%486.293313,52946.7%57.6%
48.84%436.179211,13752.0%44.4%
40.48%426.293813,11238.5%41.4%
56.41%396.190811,09956.3%56.5%
44.74%386.289812,49035.3%52.4%
44.74%385.774912,57938.5%48.0%
63.64%336.295512,53171.4%57.9%
65.63%326.294313,24788.9%56.5%
24.14%295.974010,47614.3%33.3%
41.38%295.882411,49025.0%52.9%
42.86%286.475911,22556.3%25.0%
40.00%256.369611,38123.1%58.3%
48.00%255.678211,35260.0%40.0%
36.00%256.074911,06135.7%36.4%
62.50%246.01,01911,75454.5%69.2%
58.33%245.971012,37433.3%73.3%
47.83%236.085513,59116.7%58.8%
43.48%236.285914,11650.0%40.0%
71.43%216.81,24312,48766.7%75.0%
42.86%215.975212,29833.3%50.0%
40.00%206.21,01212,81128.6%46.1%
45.00%206.383212,79730.0%60.0%
26.32%196.678813,93316.7%30.8%
26.32%195.668910,2660.0%45.5%
50.00%186.785111,30936.4%71.4%
52.94%176.082911,7830.0%75.0%
50.00%165.980911,91275.0%41.7%
62.50%166.41,0259,27955.6%71.4%
57.14%145.81,08212,12625.0%70.0%
46.15%136.28869,26137.5%60.0%
38.46%136.597112,85360.0%25.0%
46.15%136.196512,899100.0%36.4%
41.67%126.01,05712,08225.0%50.0%
66.67%127.11,29514,15950.0%75.0%
63.64%116.51,00311,93533.3%75.0%
36.36%116.667413,09450.0%33.3%
63.64%117.078310,11171.4%50.0%
36.36%116.11,06410,60920.0%50.0%
40.00%106.070311,47666.7%28.6%
60.00%106.184012,20375.0%50.0%
40.00%106.076411,72950.0%33.3%
40.00%105.585814,134100.0%33.3%
60.00%106.01,17912,61450.0%66.7%
50.00%107.190512,028100.0%28.6%
44.44%95.91,06213,23540.0%50.0%
66.67%96.383412,35133.3%83.3%
66.67%95.971012,22866.7%66.7%
55.56%95.788612,272100.0%33.3%
66.67%96.11,02415,000100.0%62.5%
50.00%84.81,02112,21625.0%75.0%
62.50%86.086212,21866.7%60.0%
50.00%85.884113,58533.3%60.0%
62.50%86.472810,59040.0%100.0%
25.00%86.067812,7370.0%28.6%
42.86%75.89059,65440.0%50.0%
71.43%76.31,08912,65775.0%66.7%
71.43%74.31,05011,288100.0%33.3%
71.43%76.081915,205100.0%60.0%
28.57%75.889614,8060.0%33.3%
57.14%76.086811,05860.0%50.0%
50.00%65.684313,0420.0%60.0%
16.67%65.193311,15633.3%0.0%
50.00%66.097112,154100.0%40.0%
0.00%63.375313,3700.0%0.0%
50.00%66.396012,8350.0%60.0%
66.67%66.092811,294100.0%33.3%
33.33%64.888710,6890.0%50.0%
20.00%55.356811,0040.0%33.3%
80.00%56.491116,3890.0%80.0%
80.00%55.284713,655100.0%75.0%
60.00%55.79367,78850.0%100.0%
80.00%56.088813,69250.0%100.0%
60.00%55.57479,88650.0%66.7%
60.00%56.785916,611100.0%50.0%
60.00%55.489312,01850.0%66.7%

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Vayne vs Kalista - Frequently Asked Questions

How does Vayne do against Kalista in League of Legends?

Kalista wins the Vayne vs Kalista matchup with a 57.1% win rate compared to Vayne's 42.9%, a 14.3 percentage point difference. This data is based on 7 recent ranked games in patch 26.14.

How does Vayne do against Kalista in the early game?

In the early game, Kalista has the advantage against Vayne with a 60.0% win rate versus 40.0%. Kalista players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Vayne do against Kalista in the late game?

In the late game, Vayne takes over the Vayne vs Kalista matchup with a 50.0% win rate compared to 50.0%. Vayne scales better into team fights and objective contests after 25 minutes.

Who wins the Vayne vs Kalista matchup?

Kalista wins the matchup against Vayne with a 57.1% win rate in League of Legends patch 26.14. The 14.3 percentage point advantage means Kalista is significantly favored in this lane matchup based on 7 games analyzed.

What is the best Vayne build against Kalista?

The best Vayne build against Kalista includes optimized core items. Check the matchup breakdown above for the full item path and build order.

What are the best Vayne runes against Kalista?

The best Vayne runes against Kalista use the Precision primary tree with Resolve secondary. This rune setup achieves a 0.0% win rate in the Vayne vs Kalista matchup. See the full rune breakdown in the matchup comparison above.

Does Vayne counter Kalista?

No, Vayne struggles against Kalista with only a 42.9% win rate. Kalista has the advantage in this matchup. Vayne players should focus on safe farming and avoiding extended trades to minimize Kalista's lead.

How do I play Vayne against Kalista?

When playing Vayne against Kalista, play cautiously and avoid Kalista's power spikes. Focus on safe farming — you outscale Kalista in the late game. Use the matchup-specific build and runes above to optimize your chances.