Vayne - League of Legends Champion
Win Rate
50.4%
Pick Rate
4.9%

Vaynevs Kalista

BMarksmanAssassin
Patch26.11
Matches776,441
LaneAll Lanes
TierAll Tiers
Last UpdatedJun 4, 2026
MethodologyData Methodology

Vayne vs Kalista is a moderate matchup in LoL patch 26.11. Vayne wins with a 52.0% win rate (+4.0%) over Kalista based on 50 games. Kalista wins the early laning phase while Vayne scales better into the late game. Below you'll find the best Vayne build, runes, laning stats, and strategies for the Vayne vs Kalista matchup.

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Vayne Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Vayne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Vayne - 52.0% win rate in this matchup
Vayne
52.0% WR
VS
Kalista vs Vayne matchup - 48.0% win rate
Kalista
48.0% WR

Who Wins the Vayne vs Kalista Matchup?

Vayne wins the Vayne vs Kalista matchup
Winner
Vayne
Matches: 50
52.0%
Win Rate
48.0%
6.0
CS / min
6.7
875
DMG / min
839
13,621
Gold / game
13,878
238
Heal / min
203
512
DMG Mitigated / min
518
0.4
CC / min
0.4
47.8%
Early Game WR
52.2%
55.6%
Late Game WR
44.4%

Vayne vs Kalista Matchup Summary

The Vayne vs Kalista matchup is a moderate matchup in League of Legends ranked play. Based on 50 recent matches analyzed, Vayne wins with a 52.0% win rate compared to Kalista's 48.0%, giving Vayne a 4.0 percentage point advantage. Game phase dynamics play a critical role here: Kalista controls the early laning stage, but Vayne outscales as the game goes longer. The matchup shifts dramatically depending on game length — Kalista needs to press advantages before Vayne reaches their power spikes, while Vayne should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in CS, where Kalista leads by 0.7 CS/min — a difference that heavily influences the outcome of trades and skirmishes. Vayne has a statistical edge, but the margin is close enough that respecting Kalista's strengths is important. Trade when cooldowns are favorable, track the enemy jungler, and build toward your strongest item spikes to convert the slight advantage into a decisive lead. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Vayne vs Kalista Laning Phase Breakdown

Vayne wins the laning phase against Kalista in League of Legends

Vayne is favored during the laning phase against Kalista, winning 3 out of 5 key stat categories. Vayne holds advantages in damage, crowd control and sustain, making them the stronger laner in this matchup.

Farming
6.0Vayne
6.7Kalista
Kalista edges out Vayne by 0.7 CS per minute — a moderate farming advantage that adds up to roughly 10 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Kalista.
Damage
875Vayne
839Kalista
Vayne deals 36 more champion damage per minute than Kalista. While noticeable in extended trades, this gap can be offset by Kalista choosing favorable fight windows, such as engaging when Vayne's key abilities are on cooldown or trading immediately after dodging a skillshot.
Economy
13,621Vayne
13,878Kalista
Vayne and Kalista generate nearly equal gold per game, with just a 257 gold difference. Neither champion has a clear economic advantage, so gold leads will depend on individual play quality, kill participation, and objective contributions.
Utility
0.4Vayne
0.4Kalista
Both Vayne and Kalista provide similar amounts of crowd control (0.0s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
750Vayne
721Kalista
Vayne and Kalista have comparable sustain profiles, with only 30 HP/min separating their healing and damage mitigation. Neither champion can out-attrition the other in lane, so trades will be decided by burst potential and ability usage rather than sustain.

Best Vayne Build Against Kalista

Berserker's Greaves is the optimal boots choice against Kalista, providing the mobility and stats Vayne needs most in this matchup. The top-performing core items for Vayne against Kalista are Essence Reaver, Experimental Hexplate and Lord Dominik's Regards. This combination gives Vayne an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Kalista. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Vayne vs Kalista matchup.

Early Game vs Late Game

Early Game
Kalista
52.2%
+4.3% advantage
Vayne early game win rateVayne47.8%
Kalista early game win rateKalista52.2%
Late Game
Vayne
55.6%
+11.1% advantage
Vayne late game win rateVayne55.6%
Kalista late game win rateKalista44.4%

During the early laning phase (first 15 minutes), Kalista has a meaningful 52.2% win rate, outperforming Vayne by 4.3 percentage points. Kalista players should look to press this advantage through aggressive trades, wave priority, and early jungle coordination.

Vayne is far superior in the late game (25+ minutes), boasting a 55.6% win rate — 11.1 points above Kalista. Extended games heavily favor Vayne, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Kalista must aggressively press their early advantage and close out the game before Vayne reaches their scaling breakpoints. If Vayne survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Vayne Runes Against Kalista

Precision rune tree - Vayne primary runes vs KalistaPrecision
Lethal Tempo - best Vayne rune vs KalistaTriumph - best Vayne rune vs KalistaLegend: Alacrity - best Vayne rune vs KalistaCoup de Grace - best Vayne rune vs Kalista
Resolve rune tree - Vayne secondary runes vs KalistaResolve
Conditioning - best Vayne rune vs KalistaOvergrowth - best Vayne rune vs Kalista
58.3% WR

Running Precision primary with Resolve secondary allows Vayne to press their advantage against Kalista, amplifying the strengths that make this a favorable matchup.


Vayne matchup data for League of Legends patch 26.11. The table below shows Vayne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vayne build, runes, laning stats, and early vs late game analysis for that specific matchup.

Vayne matchup win rates and stats in League of Legends patch 26.11
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
46.01%4766.078912,87544.3%47.4%
47.20%4476.079112,72545.4%48.6%
46.26%4285.779612,71544.9%47.3%
53.92%3956.085712,96853.2%54.6%
47.85%3726.289413,18946.8%48.6%
52.99%3516.284313,14252.5%53.4%
52.98%2856.390413,45646.2%58.8%
53.90%2696.387713,73748.2%58.0%
52.38%1895.988612,46846.1%58.2%
51.92%1566.591311,98950.0%53.4%
54.30%1516.185913,22758.5%51.2%
50.33%1516.180413,00743.8%55.2%
45.95%1485.978013,60345.3%46.3%
45.38%1306.177613,08138.2%50.7%
47.83%1156.481213,76538.5%52.6%
42.61%1156.178112,08234.0%49.2%
50.88%1145.886612,98941.2%58.7%
45.19%1046.489913,17548.7%43.1%
59.80%1026.585413,18963.5%56.0%
31.00%1005.563510,36011.1%47.3%
45.83%965.885713,16444.4%46.7%
50.53%956.31,12012,73751.6%50.0%
58.06%936.379613,00854.8%60.8%
44.09%935.862511,33042.4%45.0%
45.56%905.883011,35543.6%47.1%
45.98%876.385113,57237.9%50.0%
55.81%866.189910,74843.2%65.3%
55.95%846.21,29211,54651.4%59.2%
56.41%786.388313,43557.1%55.8%
54.84%625.981412,06158.3%52.6%
45.76%596.287712,77548.0%44.1%
51.92%526.091311,59248.1%56.0%
45.10%516.592112,14440.9%48.3%
52.00%506.087513,62147.8%55.6%
35.42%486.272110,98228.0%43.5%
58.33%486.198911,81064.0%52.2%
45.83%486.21,00510,83851.9%38.1%
50.00%466.297013,36447.4%51.9%
58.70%466.291413,67162.5%54.5%
54.55%446.287414,06357.1%53.3%
44.19%436.683913,74455.0%34.8%
26.19%425.987411,67823.5%28.0%
48.78%415.983611,64443.5%55.6%
52.50%405.683813,60737.5%56.3%
38.46%396.785410,96150.0%28.6%
41.03%396.07439,57128.6%55.6%
67.57%376.589811,52662.5%76.9%
45.95%375.683211,99840.0%50.0%
52.94%346.475912,24550.0%54.5%
52.94%346.41,05111,47452.6%53.3%
66.67%336.393813,52461.5%70.0%
48.48%336.478411,26950.0%46.1%
48.48%336.597913,30562.5%44.0%
40.63%325.382011,34442.1%38.5%
62.50%325.779613,16341.7%75.0%
40.63%326.267610,36931.6%53.9%
58.06%316.484912,13864.3%52.9%
53.33%305.685512,15255.6%52.4%
60.00%306.095312,30876.9%47.1%
43.33%306.664611,44137.5%50.0%
55.56%275.379211,00650.0%60.0%
48.15%276.283411,46543.8%54.5%
50.00%265.969311,80141.7%57.1%
50.00%266.171011,42146.1%53.9%
30.77%265.370011,00127.3%33.3%
50.00%265.883412,30154.5%46.7%
48.00%256.081612,91020.0%66.7%
44.00%256.475811,84450.0%38.5%
54.17%246.399112,32564.3%40.0%
45.83%246.085011,12557.1%30.0%
56.52%235.761010,29945.5%66.7%
45.45%226.573412,18438.5%55.6%
40.91%226.080612,81544.4%38.5%
42.11%196.292010,37245.5%37.5%
63.16%196.387012,58950.0%72.7%
42.11%195.881712,14257.1%33.3%
61.11%185.61,00813,43366.7%58.3%
62.50%166.188511,54762.5%62.5%
80.00%152.288517,36850.0%84.6%
53.33%156.498513,30150.0%54.5%
60.00%156.583311,24437.5%85.7%
46.67%156.687611,53050.0%42.9%
46.67%155.491613,99225.0%54.5%
42.86%146.482413,96675.0%30.0%
42.86%146.084113,4470.0%66.7%
53.85%136.584913,506100.0%33.3%
46.15%135.275011,57950.0%42.9%
66.67%125.61,02512,92880.0%57.1%
33.33%126.092711,90033.3%33.3%
54.55%115.61,00213,29850.0%57.1%
63.64%116.164210,20450.0%80.0%
54.55%112.982014,06866.7%40.0%
81.82%116.277512,783100.0%71.4%
54.55%113.484613,74333.3%62.5%
54.55%115.576111,64971.4%25.0%
45.45%115.69159,80875.0%28.6%
40.00%104.670811,73250.0%25.0%
60.00%105.782012,59750.0%62.5%
50.00%103.877113,23733.3%57.1%
40.00%105.592611,89340.0%40.0%
66.67%93.81,03913,79866.7%66.7%
33.33%96.11,07613,2730.0%50.0%
55.56%96.793013,145100.0%20.0%
33.33%96.085513,01833.3%33.3%
55.56%93.986012,86033.3%66.7%
50.00%85.887014,56550.0%50.0%
62.50%87.368411,84766.7%50.0%
50.00%83.288313,47975.0%25.0%
25.00%85.26909,10216.7%50.0%
37.50%85.85269,89450.0%25.0%
57.14%74.076010,75033.3%75.0%
71.43%73.674311,42580.0%50.0%
42.86%74.572311,69733.3%50.0%
28.57%74.567612,0460.0%40.0%
50.00%63.578115,0220.0%60.0%
33.33%66.882313,7790.0%50.0%
33.33%62.998912,89833.3%33.3%
66.67%65.91,00614,14350.0%75.0%
20.00%54.75778,99933.3%0.0%
40.00%52.161112,29050.0%0.0%
40.00%56.41,17614,5940.0%50.0%
80.00%56.21,02413,762100.0%66.7%
40.00%55.996213,2480.0%50.0%
40.00%56.06739,21850.0%0.0%
40.00%56.47269,89240.0%0.0%

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Vayne vs Kalista - Frequently Asked Questions

How does Vayne do against Kalista in League of Legends?

Vayne wins the Vayne vs Kalista matchup with a 52.0% win rate compared to Kalista's 48.0%, a 4.0 percentage point difference. This data is based on 50 recent ranked games in patch 26.11.

How does Vayne do against Kalista in the early game?

In the early game, Kalista has the advantage against Vayne with a 52.2% win rate versus 47.8%. Kalista players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Vayne do against Kalista in the late game?

In the late game, Vayne takes over the Vayne vs Kalista matchup with a 55.6% win rate compared to 44.4%. Vayne scales better into team fights and objective contests after 25 minutes.

Who wins the Vayne vs Kalista matchup?

Vayne wins the matchup against Kalista with a 52.0% win rate in League of Legends patch 26.11. The 4.0 percentage point advantage means Vayne is moderately favored in this lane matchup based on 50 games analyzed.

What is the best Vayne build against Kalista?

The best Vayne build against Kalista includes Essence Reaver, Experimental Hexplate, Lord Dominik's Regards with Berserker's Greaves. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Vayne runes against Kalista?

The best Vayne runes against Kalista use the Precision primary tree with Resolve secondary. This rune setup achieves a 58.3% win rate in the Vayne vs Kalista matchup. See the full rune breakdown in the matchup comparison above.

Does Vayne counter Kalista?

Yes, Vayne has a favorable matchup against Kalista with a 52.0% win rate. Vayne has a solid advantage over Kalista in lane based on current patch 26.11 data.

How do I play Vayne against Kalista?

When playing Vayne against Kalista, leverage your statistical advantages by trading aggressively during favorable windows. Play safe early and scale into your power spikes where you outperform Kalista. Build the recommended items and runes for this specific matchup for the best results.