Kalista - League of Legends Champion
Win Rate
42.4%
Pick Rate
0.7%

Kalistavs Vayne

FMarksman
Patch26.7
Matches949,984
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 20, 2026
MethodologyData Methodology

Kalista vs Vayne is a decisive matchup in LoL patch 26.7. Vayne wins with a 55.2% win rate (+10.3%) over Kalista based on 29 games. Vayne wins the early laning phase while Kalista scales better into the late game. Below you'll find the best Kalista build, runes, laning stats, and strategies for the Kalista vs Vayne matchup.

Kalista Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Kalista performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Vayne - 44.8% win rateVayne(44.8%)
Kalista - 44.8% win rate in this matchup
Kalista
44.8% WR
VS
Vayne vs Kalista matchup - 55.2% win rate
Vayne
55.2% WR

Who Wins the Kalista vs Vayne Matchup?

Vayne wins the Kalista vs Vayne matchup
Winner
Vayne
Matches: 29
44.8%
Win Rate
55.2%
6.5
CS / min
6.3
993
DMG / min
1,024
13,637
Gold / game
13,694
251
Heal / min
251
635
DMG Mitigated / min
542
0.5
CC / min
0.5
37.5%
Early Game WR
62.5%
53.9%
Late Game WR
46.1%

Kalista vs Vayne Matchup Summary

The Kalista vs Vayne matchup is a decisive matchup in League of Legends ranked play. Based on 29 recent matches analyzed, Vayne wins with a 55.2% win rate compared to Kalista's 44.8%, giving Vayne a 10.3 percentage point advantage. Game phase dynamics play a critical role here: Vayne controls the early laning stage, but Kalista outscales as the game goes longer. The matchup shifts dramatically depending on game length — Vayne needs to press advantages before Kalista reaches their power spikes, while Kalista should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in sustain, where Kalista leads by 92 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Vayne has a strong advantage in this matchup. Kalista players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Vayne overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Kalista vs Vayne Laning Phase Breakdown

Kalista wins the laning phase against Vayne in League of Legends

Kalista is favored during the laning phase against Vayne, winning 3 out of 5 key stat categories. Kalista holds advantages in farming, crowd control and sustain, making them the stronger laner in this matchup.

Farming
6.5Kalista
6.3Vayne
Kalista and Vayne farm at nearly identical rates in this matchup, with only a 0.2 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
993Kalista
1,024Vayne
Vayne deals 31 more champion damage per minute than Kalista. While noticeable in extended trades, this gap can be offset by Kalista choosing favorable fight windows, such as engaging when Vayne's key abilities are on cooldown or trading immediately after dodging a skillshot.
Economy
13,637Kalista
13,694Vayne
Kalista and Vayne generate nearly equal gold per game, with just a 57 gold difference. Neither champion has a clear economic advantage, so gold leads will depend on individual play quality, kill participation, and objective contributions.
Utility
0.5Kalista
0.5Vayne
Both Kalista and Vayne provide similar amounts of crowd control (0.0s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
886Kalista
793Vayne
Kalista heals and mitigates 92 more damage per minute than Vayne, providing moderate extra durability. This sustain edge allows Kalista to stay in lane longer between recalls and gradually win extended wars of attrition. Consider building early grievous wounds if playing Vayne.

Early Game vs Late Game

Early Game
Vayne
62.5%
+25.0% advantage
Kalista early game win rateKalista37.5%
Vayne early game win rateVayne62.5%
Late Game
Kalista
53.9%
+7.7% advantage
Kalista late game win rateKalista53.9%
Vayne late game win rateVayne46.1%

Vayne dominates the early game (first 15 minutes) with a commanding 62.5% win rate — a 25.0 percentage point lead over Kalista. This lopsided early game means Vayne can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Kalista is far superior in the late game (25+ minutes), boasting a 53.9% win rate — 7.7 points above Vayne. Extended games heavily favor Kalista, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Vayne must aggressively press their early advantage and close out the game before Kalista reaches their scaling breakpoints. If Kalista survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Kalista Runes Against Vayne

Domination rune tree - Kalista primary runes vs VayneDomination
Hail of Blades - best Kalista rune vs VayneSudden Impact - best Kalista rune vs VayneSixth Sense - best Kalista rune vs VayneTreasure Hunter - best Kalista rune vs Vayne
Inspiration rune tree - Kalista secondary runes vs VayneInspiration
Cash Back - best Kalista rune vs VayneTriple Tonic - best Kalista rune vs Vayne
100.0% WR

The Domination and Inspiration rune setup gives Kalista the best tools to compete against Vayne in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Kalista matchup data for League of Legends patch 26.7. The table below shows Kalista's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Kalista build, runes, laning stats, and early vs late game analysis for that specific matchup.

Kalista matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
42.86%636.386314,15039.3%45.7%
48.08%526.791414,44148.1%48.0%
42.86%496.51,01315,58541.2%43.8%
46.67%456.498813,88333.3%61.9%
41.03%396.083713,78946.7%37.5%
42.11%386.380014,01440.0%44.4%
48.48%336.790613,14445.0%53.9%
66.67%336.697314,17268.8%64.7%
44.83%296.599313,63737.5%53.9%
53.85%266.295714,34450.0%58.3%
40.91%226.672612,95420.0%58.3%
47.37%196.684113,41344.4%50.0%
41.18%176.381412,66530.0%57.1%
50.00%147.198114,82950.0%50.0%
42.86%146.595612,8790.0%66.7%
21.43%146.576714,67233.3%12.5%
53.85%136.595914,98925.0%66.7%
30.77%136.374811,71722.2%50.0%
45.45%116.81,02214,90950.0%42.9%
36.36%116.083511,81925.0%66.7%
37.50%85.598515,15650.0%25.0%
83.33%66.985313,13975.0%100.0%
33.33%66.497814,63625.0%50.0%
66.67%66.695414,19050.0%100.0%
40.00%56.794915,02850.0%33.3%
40.00%55.391014,76850.0%33.3%
20.00%56.380314,01250.0%0.0%
60.00%56.41,10318,9250.0%60.0%
80.00%57.31,05512,709100.0%0.0%

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Kalista vs Vayne - Frequently Asked Questions

How does Kalista do against Vayne in League of Legends?

Vayne wins the Kalista vs Vayne matchup with a 55.2% win rate compared to Kalista's 44.8%, a 10.3 percentage point difference. This data is based on 29 recent ranked games in patch 26.7.

How does Kalista do against Vayne in the early game?

In the early game, Vayne has the advantage against Kalista with a 62.5% win rate versus 37.5%. Vayne players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Kalista do against Vayne in the late game?

In the late game, Kalista takes over the Kalista vs Vayne matchup with a 53.9% win rate compared to 46.1%. Kalista scales better into team fights and objective contests after 25 minutes.

Who wins the Kalista vs Vayne matchup?

Vayne wins the matchup against Kalista with a 55.2% win rate in League of Legends patch 26.7. The 10.3 percentage point advantage means Vayne is significantly favored in this lane matchup based on 29 games analyzed.

What is the best Kalista build against Vayne?

The best Kalista build against Vayne includes optimized core items. Check the matchup breakdown above for the full item path and build order.

What are the best Kalista runes against Vayne?

The best Kalista runes against Vayne use the Domination primary tree with Inspiration secondary. This rune setup achieves a 100.0% win rate in the Kalista vs Vayne matchup. See the full rune breakdown in the matchup comparison above.

Does Kalista counter Vayne?

No, Kalista struggles against Vayne with only a 44.8% win rate. Vayne has the advantage in this matchup. Kalista players should focus on safe farming and avoiding extended trades to minimize Vayne's lead.

How do I play Kalista against Vayne?

When playing Kalista against Vayne, play cautiously and avoid Vayne's power spikes. Focus on safe farming — you outscale Vayne in the late game. Use the matchup-specific build and runes above to optimize your chances.