Ambessa - League of Legends Champion
Win Rate
49.2%
Pick Rate
2.5%

Ambessavs Karthus

DFighterAssassin
Patch26.14
Matches491,560
LaneAll Lanes
TierAll Tiers
Last UpdatedJul 21, 2026
MethodologyData Methodology

Ambessa vs Karthus is a very close matchup in LoL patch 26.14. Ambessa wins with a 50.0% win rate (+0.0%) over Karthus based on 6 games. Karthus wins the early laning phase while Ambessa scales better into the late game. Below you'll find the best Ambessa build, runes, laning stats, and strategies for the Ambessa vs Karthus matchup.

Join Our Discord
Bug reports, feature requests & developer chat
Join Discord
Metabot Logo
MetaBot Desktop
Counter picks in champ select

Ambessa Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Ambessa performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Ambessa - 50.0% win rate in this matchup
Ambessa
50.0% WR
VS
Karthus vs Ambessa matchup - 50.0% win rate
Karthus
50.0% WR

Who Wins the Ambessa vs Karthus Matchup?

Ambessa wins the Ambessa vs Karthus matchup
Winner
Ambessa
Matches: 6
50.0%
Win Rate
50.0%
2.1
CS / min
2.5
633
DMG / min
1,110
10,515
Gold / game
11,409
415
Heal / min
256
1,100
DMG Mitigated / min
383
0.4
CC / min
0.7
25.0%
Early Game WR
75.0%
100.0%
Late Game WR
0.0%

Ambessa vs Karthus Matchup Summary

The Ambessa vs Karthus matchup is essentially a coin-flip matchup in League of Legends ranked play. Based on 6 recent matches analyzed, Ambessa wins with a 50.0% win rate compared to Karthus's 50.0%, giving Ambessa a 0.0 percentage point advantage. Game phase dynamics play a critical role here: Karthus controls the early laning stage, but Ambessa outscales as the game goes longer. The matchup shifts dramatically depending on game length — Karthus needs to press advantages before Ambessa reaches their power spikes, while Ambessa should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in sustain, where Ambessa leads by 876 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Ambessa has a statistical edge, but the margin is close enough that respecting Karthus's strengths is important. Trade when cooldowns are favorable, track the enemy jungler, and build toward your strongest item spikes to convert the slight advantage into a decisive lead. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Ambessa vs Karthus Laning Phase Breakdown

Karthus wins the laning phase against Ambessa in League of Legends

Karthus is favored during the laning phase against Ambessa, winning 4 out of 5 key stat categories. Karthus holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.

Farming
2.1Ambessa
2.5Karthus
Karthus edges out Ambessa by 0.4 CS per minute — a moderate farming advantage that adds up to roughly 6 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Karthus.
Damage
633Ambessa
1,110Karthus
Karthus heavily out-damages Ambessa by 477 DMG/min, dominating both short trades and all-in fights. Ambessa should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Karthus's sustained damage advantage take over.
Economy
10,515Ambessa
11,409Karthus
Karthus generates a commanding 895 more gold per game than Ambessa. This substantial economic advantage means Karthus consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Ambessa should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.4Ambessa
0.7Karthus
Karthus provides 0.3 seconds more crowd control per minute than Ambessa, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Karthus coordinate with their jungler and control the pace of skirmishes.
Sustain
1,515Ambessa
639Karthus
Ambessa vastly out-sustains Karthus, healing and mitigating 876 more damage per minute. This massive durability gap means Ambessa can absorb significant punishment and remain in lane while Karthus is forced to recall. Building grievous wounds early is essential for Karthus, and focusing on burst trade patterns rather than sustained fights is critical.

Best Ambessa Build Against Karthus

Mercury's Treads is the optimal boots choice against Karthus, providing the mobility and stats Ambessa needs most in this matchup. The top-performing core items for Ambessa against Karthus are Voltaic Cyclosword, Axiom Arc and Death's Dance. This combination gives Ambessa an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Karthus. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Ambessa vs Karthus matchup.

Early Game vs Late Game

Early Game
Karthus
75.0%
+50.0% advantage
Ambessa early game win rateAmbessa25.0%
Karthus early game win rateKarthus75.0%
Late Game
Ambessa
100.0%
+100.0% advantage
Ambessa late game win rateAmbessa100.0%
Karthus late game win rateKarthus0.0%

Karthus dominates the early game (first 15 minutes) with a commanding 75.0% win rate — a 50.0 percentage point lead over Ambessa. This lopsided early game means Karthus can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Ambessa is far superior in the late game (25+ minutes), boasting a 100.0% win rate — 100.0 points above Karthus. Extended games heavily favor Ambessa, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Karthus must aggressively press their early advantage and close out the game before Ambessa reaches their scaling breakpoints. If Ambessa survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Ambessa Runes Against Karthus

Precision rune tree - Ambessa primary runes vs KarthusPrecision
Conqueror - best Ambessa rune vs KarthusTriumph - best Ambessa rune vs KarthusLegend: Haste - best Ambessa rune vs KarthusLast Stand - best Ambessa rune vs Karthus
Inspiration rune tree - Ambessa secondary runes vs KarthusInspiration
Cosmic Insight - best Ambessa rune vs KarthusMagical Footwear - best Ambessa rune vs Karthus
50.0% WR

The Precision primary with Inspiration secondary combination helps Ambessa maximize their potential in this closely contested matchup, providing the right mix of offensive and defensive tools to edge out Karthus.


Ambessa matchup data for League of Legends patch 26.14. The table below shows Ambessa's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Ambessa build, runes, laning stats, and early vs late game analysis for that specific matchup.

Ambessa matchup win rates and stats in League of Legends patch 26.14
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
57.89%765.589011,11866.7%52.2%
40.85%716.093211,39026.1%47.9%
42.65%686.988711,02741.4%43.6%
56.06%665.983810,72428.0%73.2%
48.33%606.493912,09147.1%48.8%
52.73%555.783912,34455.0%51.4%
46.30%545.672911,96042.9%47.5%
40.38%526.270910,15454.2%28.6%
40.00%503.179411,34345.8%34.6%
53.19%475.977411,53352.9%53.3%
50.00%443.089313,22846.1%51.6%
40.91%446.07349,21327.3%54.5%
48.84%435.585811,32745.5%52.4%
50.00%421.776111,81145.5%55.0%
43.59%395.093611,64754.5%39.3%
58.97%396.11,32111,98441.7%66.7%
53.85%396.589311,89346.1%57.7%
37.84%376.393311,45141.7%36.0%
27.27%335.983212,23730.8%25.0%
57.58%336.575811,79750.0%60.9%
62.50%326.386512,06972.7%57.1%
59.38%326.51,14813,11583.3%53.9%
54.84%311.767411,61438.5%66.7%
51.61%315.985611,51833.3%63.2%
46.67%306.397110,90550.0%44.4%
56.67%305.883810,14169.2%47.1%
58.62%296.194110,13966.7%50.0%
34.48%291.982111,55637.5%30.8%
46.43%285.874110,52838.5%53.3%
51.85%275.293611,66145.5%56.3%
59.26%271.078712,62058.3%60.0%
66.67%276.11,04712,56481.8%56.3%
50.00%266.71,03110,89050.0%50.0%
57.69%265.281710,91261.5%53.9%
56.00%256.091411,37237.5%64.7%
60.00%256.01,00212,74370.0%53.3%
24.00%255.389911,97612.5%29.4%
33.33%245.673410,32225.0%41.7%
29.17%246.295610,88333.3%26.7%
37.50%245.474710,64410.0%57.1%
52.17%232.086413,89960.0%50.0%
60.87%235.778511,57170.0%53.9%
43.48%236.167110,29625.0%53.3%
50.00%221.863711,60736.4%63.6%
68.18%224.675811,52150.0%100.0%
59.09%226.41,13912,09360.0%58.3%
50.00%221.36069,65660.0%28.6%
36.36%225.886511,28257.1%26.7%
35.00%201.976212,53212.5%50.0%
45.00%202.981412,26562.5%33.3%
45.00%205.898310,31550.0%42.9%
47.37%191.788413,76071.4%33.3%
52.63%197.284912,07137.5%63.6%
26.32%190.960310,95744.4%10.0%
47.37%191.475813,11260.0%42.9%
31.58%195.181511,4010.0%35.3%
44.44%181.974911,03837.5%50.0%
50.00%186.586511,04262.5%40.0%
47.06%171.873510,44254.5%33.3%
47.06%175.972911,96620.0%58.3%
56.25%161.179014,10550.0%60.0%
46.67%156.181412,31442.9%50.0%
53.33%152.290915,42750.0%53.9%
13.33%155.190713,0930.0%20.0%
71.43%145.479510,98650.0%87.5%
71.43%141.41,05014,965100.0%66.7%
64.29%141.475713,57550.0%70.0%
61.54%136.587411,31457.1%66.7%
61.54%135.388310,99825.0%77.8%
50.00%125.899411,38450.0%50.0%
50.00%126.282112,31150.0%50.0%
72.73%116.21,10214,51875.0%71.4%
45.45%111.997114,32125.0%57.1%
54.55%111.898814,48133.3%62.5%
30.00%101.282813,43520.0%40.0%
70.00%106.187412,37566.7%75.0%
44.44%95.51,03914,0010.0%66.7%
55.56%96.31,17210,33460.0%50.0%
55.56%91.367314,16833.3%66.7%
62.50%81.21,02016,821100.0%57.1%
50.00%85.41,01512,31866.7%40.0%
87.50%85.91,07311,005100.0%80.0%
75.00%81.288414,47175.0%75.0%
42.86%77.07889,33860.0%0.0%
57.14%72.786715,49650.0%60.0%
85.71%72.21,01216,629100.0%80.0%
57.14%77.05468,42480.0%0.0%
28.57%76.71,08012,67925.0%33.3%
28.57%73.976512,17150.0%0.0%
57.14%76.286110,82625.0%100.0%
100.00%61.11,21815,966100.0%100.0%
66.67%63.287116,512100.0%60.0%
16.67%62.086613,9750.0%20.0%
50.00%62.163310,51525.0%100.0%
33.33%65.270010,424100.0%20.0%
50.00%65.386211,3490.0%75.0%
50.00%65.05659,17866.7%33.3%
33.33%61.374312,69825.0%50.0%
60.00%50.95199,13375.0%0.0%
60.00%56.11,16913,485100.0%33.3%
80.00%52.480511,486100.0%75.0%

Get the MetaBot Desktop App

Level up your gameplay with real-time overlays, automatic game detection, and instant stats — all on your desktop.

In-game overlaysAuto game detectionMulti-game supportPersonal dashboard
Download NowFree download
🔍

Help us maintain accuracy! If you notice incorrect stats, missing data, or any issues, your feedback directly improves the quality of our data for the entire community.

Report an Issue

Ambessa vs Karthus - Frequently Asked Questions

How does Ambessa do against Karthus in League of Legends?

Ambessa wins the Ambessa vs Karthus matchup with a 50.0% win rate compared to Karthus's 50.0%, a 0.0 percentage point difference. This data is based on 6 recent ranked games in patch 26.14.

How does Ambessa do against Karthus in the early game?

In the early game, Karthus has the advantage against Ambessa with a 75.0% win rate versus 25.0%. Karthus players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Ambessa do against Karthus in the late game?

In the late game, Ambessa takes over the Ambessa vs Karthus matchup with a 100.0% win rate compared to 0.0%. Ambessa scales better into team fights and objective contests after 25 minutes.

Who wins the Ambessa vs Karthus matchup?

Ambessa wins the matchup against Karthus with a 50.0% win rate in League of Legends patch 26.14. The 0.0 percentage point advantage means Ambessa is slightly favored in this lane matchup based on 6 games analyzed.

What is the best Ambessa build against Karthus?

The best Ambessa build against Karthus includes Voltaic Cyclosword, Axiom Arc, Death's Dance with Mercury's Treads. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Ambessa runes against Karthus?

The best Ambessa runes against Karthus use the Precision primary tree with Inspiration secondary. This rune setup achieves a 50.0% win rate in the Ambessa vs Karthus matchup. See the full rune breakdown in the matchup comparison above.

Does Ambessa counter Karthus?

Yes, Ambessa has a favorable matchup against Karthus with a 50.0% win rate. Ambessa slightly edges out Karthus in lane based on current patch 26.14 data.

How do I play Ambessa against Karthus?

When playing Ambessa against Karthus, leverage your statistical advantages by trading aggressively during favorable windows. Play safe early and scale into your power spikes where you outperform Karthus. Build the recommended items and runes for this specific matchup for the best results.