Annie - League of Legends Champion
Win Rate
52.0%
Pick Rate
1.3%

Annievs Cassiopeia

SMageSupport
Patch26.14
Matches491,560
LaneAll Lanes
TierAll Tiers
Last UpdatedJul 21, 2026
MethodologyData Methodology

Annie vs Cassiopeia is a decisive matchup in LoL patch 26.14. Annie wins with a 57.1% win rate (+14.3%) over Cassiopeia based on 7 games. Annie holds the advantage in both the early and late game. Below you'll find the best Annie build, runes, laning stats, and strategies for the Annie vs Cassiopeia matchup.

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Annie Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Annie performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Annie - 57.1% win rate in this matchup
Annie
57.1% WR
VS
Cassiopeia vs Annie matchup - 42.9% win rate
Cassiopeia
42.9% WR

Who Wins the Annie vs Cassiopeia Matchup?

Annie wins the Annie vs Cassiopeia matchup
Winner
Annie
Matches: 7
57.1%
Win Rate
42.9%
6.0
CS / min
6.2
847
DMG / min
703
12,204
Gold / game
12,072
69
Heal / min
239
388
DMG Mitigated / min
487
0.9
CC / min
1.1
50.0%
Early Game WR
50.0%
60.0%
Late Game WR
40.0%

Annie vs Cassiopeia Matchup Summary

The Annie vs Cassiopeia matchup is a decisive matchup in League of Legends ranked play. Based on 7 recent matches analyzed, Annie wins with a 57.1% win rate compared to Cassiopeia's 42.9%, giving Annie a 14.3 percentage point advantage. Annie dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Cassiopeia players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Cassiopeia leads by 270 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Annie players can confidently pick into Cassiopeia and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Cassiopeia away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Annie vs Cassiopeia Laning Phase Breakdown

Cassiopeia wins the laning phase against Annie in League of Legends

Cassiopeia is favored during the laning phase against Annie, winning 3 out of 5 key stat categories. Cassiopeia holds advantages in farming, crowd control and sustain, making them the stronger laner in this matchup.

Farming
6.0Annie
6.2Cassiopeia
Annie and Cassiopeia farm at nearly identical rates in this matchup, with only a 0.2 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
847Annie
703Cassiopeia
Annie heavily out-damages Cassiopeia by 144 DMG/min, dominating both short trades and all-in fights. Cassiopeia should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Annie's sustained damage advantage take over.
Economy
12,204Annie
12,072Cassiopeia
Annie and Cassiopeia generate nearly equal gold per game, with just a 133 gold difference. Neither champion has a clear economic advantage, so gold leads will depend on individual play quality, kill participation, and objective contributions.
Utility
0.9Annie
1.1Cassiopeia
Both Annie and Cassiopeia provide similar amounts of crowd control (0.2s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
456Annie
726Cassiopeia
Cassiopeia vastly out-sustains Annie, healing and mitigating 270 more damage per minute. This massive durability gap means Cassiopeia can absorb significant punishment and remain in lane while Annie is forced to recall. Building grievous wounds early is essential for Annie, and focusing on burst trade patterns rather than sustained fights is critical.

Best Annie Build Against Cassiopeia

Swiftmarch is the optimal boots choice against Cassiopeia, providing the mobility and stats Annie needs most in this matchup. The top-performing core items for Annie against Cassiopeia are Liandry's Torment, Hextech Rocketbelt and Malignance. This combination gives Annie an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Annie vs Cassiopeia matchup.

Early Game vs Late Game

Early Game
Annie
50.0%
+0.0% advantage
Annie early game win rateAnnie50.0%
Cassiopeia early game win rateCassiopeia50.0%
Late Game
Annie
60.0%
+20.0% advantage
Annie late game win rateAnnie60.0%
Cassiopeia late game win rateCassiopeia40.0%

The early game (first 15 minutes) is a toss-up between Annie and Cassiopeia, with Annie holding a razor-thin 50.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.

Annie is far superior in the late game (25+ minutes), boasting a 60.0% win rate — 20.0 points above Cassiopeia. Extended games heavily favor Annie, whose kit and scaling make them a dominant force in team fights and objective control.

Annie holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Cassiopeia players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Annie Runes Against Cassiopeia

Domination rune tree - Annie primary runes vs CassiopeiaDomination
Electrocute - best Annie rune vs CassiopeiaCheap Shot - best Annie rune vs CassiopeiaGrisly Mementos - best Annie rune vs CassiopeiaRelentless Hunter - best Annie rune vs Cassiopeia
Sorcery rune tree - Annie secondary runes vs CassiopeiaSorcery
Absolute Focus - best Annie rune vs CassiopeiaAxiom Arcanist - best Annie rune vs Cassiopeia
50.0% WR

Running Domination primary with Sorcery secondary allows Annie to press their advantage against Cassiopeia, amplifying the strengths that make this a favorable matchup.


Annie matchup data for League of Legends patch 26.14. The table below shows Annie's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Annie build, runes, laning stats, and early vs late game analysis for that specific matchup.

Annie matchup win rates and stats in League of Legends patch 26.14
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
55.56%815.693311,33651.5%58.3%
47.89%716.091110,69742.1%54.5%
61.02%595.291910,86443.5%72.2%
65.91%445.795911,13850.0%76.9%
59.09%445.479610,91152.9%63.0%
48.84%434.875010,24635.7%55.2%
57.14%425.31,02711,45438.9%70.8%
53.85%395.293011,39964.3%48.0%
48.57%355.99419,48038.9%58.8%
50.00%325.678510,35241.7%55.0%
44.44%275.367210,04930.8%57.1%
44.44%274.992710,28858.3%33.3%
48.00%255.81,07813,85085.7%33.3%
47.83%235.87909,97610.0%76.9%
47.83%235.492110,61950.0%46.7%
60.87%235.286910,80562.5%60.0%
31.82%225.693510,51825.0%35.7%
50.00%224.478510,88716.7%62.5%
38.10%215.171311,68025.0%46.1%
63.16%194.89538,80744.4%80.0%
38.89%185.187610,45622.2%55.6%
47.06%175.482012,29550.0%46.1%
62.50%166.21,09211,21662.5%62.5%
50.00%165.18648,19245.5%60.0%
40.00%155.792811,37916.7%55.6%
33.33%152.67249,93833.3%33.3%
42.86%145.78299,71257.1%28.6%
46.15%135.083711,28060.0%37.5%
69.23%135.189810,97366.7%70.0%
76.92%136.093511,33980.0%75.0%
61.54%135.688410,60175.0%55.6%
41.67%125.08329,73133.3%50.0%
50.00%125.26476,84050.0%50.0%
50.00%125.97469,47150.0%50.0%
72.73%116.31,13513,85866.7%75.0%
54.55%115.568310,77966.7%50.0%
36.36%114.381510,46450.0%28.6%
80.00%106.990410,29966.7%100.0%
50.00%102.86539,28750.0%50.0%
40.00%104.080011,34150.0%33.3%
22.22%95.977511,5310.0%33.3%
11.11%93.57189,5990.0%20.0%
77.78%94.996711,33350.0%85.7%
77.78%92.06419,528100.0%66.7%
62.50%86.092313,01866.7%60.0%
57.14%76.084712,20450.0%60.0%
42.86%71.35858,52075.0%0.0%
28.57%76.41,03212,3910.0%40.0%
71.43%71.47079,557100.0%60.0%
33.33%62.263810,3320.0%50.0%
16.67%65.693713,9620.0%20.0%
16.67%66.27047,41620.0%0.0%
83.33%65.11,0719,25366.7%100.0%
33.33%66.171911,309100.0%20.0%
66.67%66.21,05613,8590.0%66.7%
66.67%62.085012,9120.0%66.7%
20.00%55.785011,3010.0%33.3%
80.00%55.685010,8890.0%100.0%
80.00%56.07649,26866.7%100.0%
60.00%55.372811,47050.0%66.7%
80.00%54.878310,313100.0%50.0%
40.00%53.999612,17250.0%33.3%
40.00%57.01,29011,2560.0%66.7%
80.00%53.88219,389100.0%50.0%

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Annie vs Cassiopeia - Frequently Asked Questions

How does Annie do against Cassiopeia in League of Legends?

Annie wins the Annie vs Cassiopeia matchup with a 57.1% win rate compared to Cassiopeia's 42.9%, a 14.3 percentage point difference. This data is based on 7 recent ranked games in patch 26.14.

How does Annie do against Cassiopeia in the early game?

In the early game, Annie has the advantage against Cassiopeia with a 50.0% win rate versus 50.0%. Annie players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Annie do against Cassiopeia in the late game?

In the late game, Annie takes over the Annie vs Cassiopeia matchup with a 60.0% win rate compared to 40.0%. Annie scales better into team fights and objective contests after 25 minutes.

Who wins the Annie vs Cassiopeia matchup?

Annie wins the matchup against Cassiopeia with a 57.1% win rate in League of Legends patch 26.14. The 14.3 percentage point advantage means Annie is significantly favored in this lane matchup based on 7 games analyzed.

What is the best Annie build against Cassiopeia?

The best Annie build against Cassiopeia includes Liandry's Torment, Hextech Rocketbelt, Malignance with Swiftmarch. Check the matchup breakdown above for the full item path and build order.

What are the best Annie runes against Cassiopeia?

The best Annie runes against Cassiopeia use the Domination primary tree with Sorcery secondary. This rune setup achieves a 50.0% win rate in the Annie vs Cassiopeia matchup. See the full rune breakdown in the matchup comparison above.

Does Annie counter Cassiopeia?

Yes, Annie has a favorable matchup against Cassiopeia with a 57.1% win rate. Annie strongly counters Cassiopeia in lane based on current patch 26.14 data.

How do I play Annie against Cassiopeia?

When playing Annie against Cassiopeia, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.