Annie - League of Legends Champion
Win Rate
48.8%
Pick Rate
1.9%

Annievs Cassiopeia

DMageSupport
Patch26.9
Matches514,344
LaneAll Lanes
TierAll Tiers
Last UpdatedMay 9, 2026
MethodologyData Methodology

Annie vs Cassiopeia is a decisive matchup in LoL patch 26.9. Annie wins with a 63.6% win rate (+27.3%) over Cassiopeia based on 11 games. Cassiopeia wins the early laning phase while Annie scales better into the late game. Below you'll find the best Annie build, runes, laning stats, and strategies for the Annie vs Cassiopeia matchup.

Annie Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Annie performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Cassiopeia - 63.6% win rateCassiopeia(63.6%)
Annie - 63.6% win rate in this matchup
Annie
63.6% WR
VS
Cassiopeia vs Annie matchup - 36.4% win rate
Cassiopeia
36.4% WR

Who Wins the Annie vs Cassiopeia Matchup?

Annie wins the Annie vs Cassiopeia matchup
Winner
Annie
Matches: 11
63.6%
Win Rate
36.4%
6.5
CS / min
6.4
1,106
DMG / min
820
12,856
Gold / game
12,003
77
Heal / min
329
451
DMG Mitigated / min
571
1.1
CC / min
1.3
33.3%
Early Game WR
66.7%
75.0%
Late Game WR
25.0%

Annie vs Cassiopeia Matchup Summary

The Annie vs Cassiopeia matchup is a decisive matchup in League of Legends ranked play. Based on 11 recent matches analyzed, Annie wins with a 63.6% win rate compared to Cassiopeia's 36.4%, giving Annie a 27.3 percentage point advantage. Game phase dynamics play a critical role here: Cassiopeia controls the early laning stage, but Annie outscales as the game goes longer. The matchup shifts dramatically depending on game length — Cassiopeia needs to press advantages before Annie reaches their power spikes, while Annie should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in sustain, where Cassiopeia leads by 373 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Annie players can confidently pick into Cassiopeia and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Cassiopeia away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Annie vs Cassiopeia Laning Phase Breakdown

Annie wins the laning phase against Cassiopeia in League of Legends

Annie is favored during the laning phase against Cassiopeia, winning 3 out of 5 key stat categories. Annie holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.

Farming
6.5Annie
6.4Cassiopeia
Annie and Cassiopeia farm at nearly identical rates in this matchup, with only a 0.1 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
1,106Annie
820Cassiopeia
Annie heavily out-damages Cassiopeia by 286 DMG/min, dominating both short trades and all-in fights. Cassiopeia should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Annie's sustained damage advantage take over.
Economy
12,856Annie
12,003Cassiopeia
Annie generates a commanding 853 more gold per game than Cassiopeia. This substantial economic advantage means Annie consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Cassiopeia should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
1.1Annie
1.3Cassiopeia
Both Annie and Cassiopeia provide similar amounts of crowd control (0.2s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
527Annie
901Cassiopeia
Cassiopeia vastly out-sustains Annie, healing and mitigating 373 more damage per minute. This massive durability gap means Cassiopeia can absorb significant punishment and remain in lane while Annie is forced to recall. Building grievous wounds early is essential for Annie, and focusing on burst trade patterns rather than sustained fights is critical.

Best Annie Build Against Cassiopeia

Crimson Lucidity is the optimal boots choice against Cassiopeia, providing the mobility and stats Annie needs most in this matchup. The top-performing core items for Annie against Cassiopeia are Stormsurge, Shadowflame and Malignance. This combination gives Annie an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 4 games — well above average and making it the top item path against Cassiopeia. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Annie vs Cassiopeia matchup.

Early Game vs Late Game

Early Game
Cassiopeia
66.7%
+33.3% advantage
Annie early game win rateAnnie33.3%
Cassiopeia early game win rateCassiopeia66.7%
Late Game
Annie
75.0%
+50.0% advantage
Annie late game win rateAnnie75.0%
Cassiopeia late game win rateCassiopeia25.0%

Cassiopeia dominates the early game (first 15 minutes) with a commanding 66.7% win rate — a 33.3 percentage point lead over Annie. This lopsided early game means Cassiopeia can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Annie is far superior in the late game (25+ minutes), boasting a 75.0% win rate — 50.0 points above Cassiopeia. Extended games heavily favor Annie, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Cassiopeia must aggressively press their early advantage and close out the game before Annie reaches their scaling breakpoints. If Annie survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Annie Runes Against Cassiopeia

Sorcery rune tree - Annie primary runes vs CassiopeiaSorcery
Deathfire Touch - best Annie rune vs CassiopeiaManaflow Band - best Annie rune vs CassiopeiaTranscendence - best Annie rune vs CassiopeiaScorch - best Annie rune vs Cassiopeia
Inspiration rune tree - Annie secondary runes vs CassiopeiaInspiration
Triple Tonic - best Annie rune vs CassiopeiaCosmic Insight - best Annie rune vs Cassiopeia
100.0% WR

Running Sorcery primary with Inspiration secondary allows Annie to press their advantage against Cassiopeia, amplifying the strengths that make this a favorable matchup.


Annie matchup data for League of Legends patch 26.9. The table below shows Annie's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Annie build, runes, laning stats, and early vs late game analysis for that specific matchup.

Annie matchup win rates and stats in League of Legends patch 26.9
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
65.38%1045.792411,39365.8%65.1%
49.50%1016.191211,42355.8%42.9%
47.13%876.287111,69739.4%51.9%
53.85%656.01,11112,45863.0%47.4%
51.67%605.585312,37850.0%52.5%
60.00%605.695311,21556.5%62.2%
51.79%565.790811,67252.2%51.5%
47.27%555.379110,37641.4%53.9%
54.00%506.095712,00247.8%59.3%
55.10%495.81,01012,81347.4%60.0%
56.25%485.097811,08959.1%53.9%
40.00%456.491910,30733.3%53.3%
43.18%445.481210,60260.0%34.5%
41.86%436.271010,36628.6%54.5%
46.34%415.386710,95536.8%54.5%
35.00%405.984511,56933.3%36.0%
52.63%385.69499,90045.5%62.5%
57.14%356.092510,21846.7%65.0%
50.00%325.878310,85235.7%61.1%
38.71%315.81,01911,07650.0%29.4%
41.38%295.878010,57925.0%52.9%
37.93%295.71,04811,81633.3%41.2%
42.31%266.190111,42136.4%46.7%
60.00%255.694511,86240.0%73.3%
52.00%256.199411,03541.7%61.5%
64.00%256.285112,24772.7%57.1%
41.67%242.673110,33437.5%43.8%
52.17%236.488810,90466.7%36.4%
34.78%235.995510,98250.0%26.7%
50.00%226.073910,13254.5%45.5%
57.14%216.089611,81066.7%44.4%
42.86%216.488611,41227.3%60.0%
47.62%215.889510,76750.0%45.5%
33.33%215.57849,93218.2%50.0%
38.10%215.891612,22040.0%37.5%
55.00%205.590611,83683.3%42.9%
57.89%191.358710,12116.7%76.9%
66.67%185.586911,95820.0%84.6%
52.94%175.08879,79850.0%55.6%
41.18%176.38259,56540.0%42.9%
70.59%174.798410,69687.5%55.6%
52.94%175.899411,46557.1%50.0%
75.00%165.296411,15066.7%80.0%
62.50%163.57889,73866.7%60.0%
30.77%133.378811,27340.0%25.0%
50.00%121.878810,18450.0%50.0%
66.67%125.789410,86183.3%50.0%
41.67%123.884910,05633.3%50.0%
18.18%111.36039,3610.0%33.3%
45.45%111.579610,67750.0%42.9%
45.45%112.96838,40071.4%0.0%
63.64%116.51,10612,85633.3%75.0%
54.55%111.25968,52575.0%42.9%
63.64%115.893411,28250.0%71.4%
20.00%106.188510,30140.0%0.0%
50.00%106.092511,300100.0%28.6%
33.33%94.884010,86525.0%40.0%
33.33%91.458410,3830.0%37.5%
55.56%94.89389,57766.7%33.3%
44.44%91.45148,19940.0%50.0%
75.00%86.01,03013,586100.0%66.7%
37.50%85.391812,0000.0%50.0%
75.00%86.681810,55266.7%100.0%
62.50%84.589913,7950.0%62.5%
12.50%85.090510,1230.0%25.0%
62.50%82.46269,38425.0%100.0%
62.50%81.66608,71975.0%50.0%
28.57%72.872010,7390.0%40.0%
42.86%75.91,0018,33440.0%50.0%
57.14%76.293011,82966.7%50.0%
28.57%71.664210,15650.0%20.0%
57.14%75.489711,72150.0%66.7%
33.33%65.58718,61125.0%50.0%
33.33%61.149610,3660.0%50.0%
50.00%66.41,0149,50860.0%0.0%
33.33%62.37258,77633.3%33.3%
33.33%65.178312,6200.0%40.0%
50.00%66.16878,49840.0%100.0%
83.33%65.071611,782100.0%75.0%
16.67%65.39979,2520.0%50.0%
20.00%51.24058,2150.0%50.0%
60.00%51.95926,23760.0%0.0%
80.00%53.76278,934100.0%50.0%
60.00%55.17369,418100.0%0.0%
60.00%55.68369,56166.7%50.0%
40.00%55.96618,81350.0%0.0%
80.00%54.81,24812,73150.0%100.0%
60.00%51.678710,62966.7%50.0%
40.00%52.564010,3860.0%50.0%
40.00%51.67248,9480.0%66.7%

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Annie vs Cassiopeia - Frequently Asked Questions

How does Annie do against Cassiopeia in League of Legends?

Annie wins the Annie vs Cassiopeia matchup with a 63.6% win rate compared to Cassiopeia's 36.4%, a 27.3 percentage point difference. This data is based on 11 recent ranked games in patch 26.9.

How does Annie do against Cassiopeia in the early game?

In the early game, Cassiopeia has the advantage against Annie with a 66.7% win rate versus 33.3%. Cassiopeia players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Annie do against Cassiopeia in the late game?

In the late game, Annie takes over the Annie vs Cassiopeia matchup with a 75.0% win rate compared to 25.0%. Annie scales better into team fights and objective contests after 25 minutes.

Who wins the Annie vs Cassiopeia matchup?

Annie wins the matchup against Cassiopeia with a 63.6% win rate in League of Legends patch 26.9. The 27.3 percentage point advantage means Annie is significantly favored in this lane matchup based on 11 games analyzed.

What is the best Annie build against Cassiopeia?

The best Annie build against Cassiopeia includes Stormsurge, Shadowflame, Malignance with Crimson Lucidity. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Annie runes against Cassiopeia?

The best Annie runes against Cassiopeia use the Sorcery primary tree with Inspiration secondary. This rune setup achieves a 100.0% win rate in the Annie vs Cassiopeia matchup. See the full rune breakdown in the matchup comparison above.

Does Annie counter Cassiopeia?

Yes, Annie has a favorable matchup against Cassiopeia with a 63.6% win rate. Annie strongly counters Cassiopeia in lane based on current patch 26.9 data.

How do I play Annie against Cassiopeia?

When playing Annie against Cassiopeia, leverage your statistical advantages by trading aggressively during favorable windows. Play safe early and scale into your power spikes where you outperform Cassiopeia. Build the recommended items and runes for this specific matchup for the best results.