
Annievs Cassiopeia
Annie vs Cassiopeia is a decisive matchup in LoL patch 26.14. Annie wins with a 57.1% win rate (+14.3%) over Cassiopeia based on 7 games. Annie holds the advantage in both the early and late game. Below you'll find the best Annie build, runes, laning stats, and strategies for the Annie vs Cassiopeia matchup.
Annie Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Annie performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Annie vs Cassiopeia Matchup?

Annie vs Cassiopeia Matchup Summary
The Annie vs Cassiopeia matchup is a decisive matchup in League of Legends ranked play. Based on 7 recent matches analyzed, Annie wins with a 57.1% win rate compared to Cassiopeia's 42.9%, giving Annie a 14.3 percentage point advantage. Annie dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Cassiopeia players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Cassiopeia leads by 270 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Annie players can confidently pick into Cassiopeia and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Cassiopeia away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Annie vs Cassiopeia Laning Phase Breakdown
Cassiopeia is favored during the laning phase against Annie, winning 3 out of 5 key stat categories. Cassiopeia holds advantages in farming, crowd control and sustain, making them the stronger laner in this matchup.
Best Annie Build Against Cassiopeia
Swiftmarch is the optimal boots choice against Cassiopeia, providing the mobility and stats Annie needs most in this matchup. The top-performing core items for Annie against Cassiopeia are Liandry's Torment, Hextech Rocketbelt and Malignance. This combination gives Annie an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Annie vs Cassiopeia matchup.
Early Game vs Late Game
The early game (first 15 minutes) is a toss-up between Annie and Cassiopeia, with Annie holding a razor-thin 50.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.
Annie is far superior in the late game (25+ minutes), boasting a 60.0% win rate — 20.0 points above Cassiopeia. Extended games heavily favor Annie, whose kit and scaling make them a dominant force in team fights and objective control.
Annie holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Cassiopeia players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.
Best Annie Runes Against Cassiopeia
Running Domination primary with Sorcery secondary allows Annie to press their advantage against Cassiopeia, amplifying the strengths that make this a favorable matchup.
Annie matchup data for League of Legends patch 26.14. The table below shows Annie's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Annie build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 55.56% | 81 | 5.6 | 933 | 11,336 | 51.5% | 58.3% | |
| 47.89% | 71 | 6.0 | 911 | 10,697 | 42.1% | 54.5% | |
| 61.02% | 59 | 5.2 | 919 | 10,864 | 43.5% | 72.2% | |
| 65.91% | 44 | 5.7 | 959 | 11,138 | 50.0% | 76.9% | |
| 59.09% | 44 | 5.4 | 796 | 10,911 | 52.9% | 63.0% | |
| 48.84% | 43 | 4.8 | 750 | 10,246 | 35.7% | 55.2% | |
| 57.14% | 42 | 5.3 | 1,027 | 11,454 | 38.9% | 70.8% | |
| 53.85% | 39 | 5.2 | 930 | 11,399 | 64.3% | 48.0% | |
| 48.57% | 35 | 5.9 | 941 | 9,480 | 38.9% | 58.8% | |
| 50.00% | 32 | 5.6 | 785 | 10,352 | 41.7% | 55.0% | |
| 44.44% | 27 | 5.3 | 672 | 10,049 | 30.8% | 57.1% | |
| 44.44% | 27 | 4.9 | 927 | 10,288 | 58.3% | 33.3% | |
| 48.00% | 25 | 5.8 | 1,078 | 13,850 | 85.7% | 33.3% | |
| 47.83% | 23 | 5.8 | 790 | 9,976 | 10.0% | 76.9% | |
| 47.83% | 23 | 5.4 | 921 | 10,619 | 50.0% | 46.7% | |
| 60.87% | 23 | 5.2 | 869 | 10,805 | 62.5% | 60.0% | |
| 31.82% | 22 | 5.6 | 935 | 10,518 | 25.0% | 35.7% | |
| 50.00% | 22 | 4.4 | 785 | 10,887 | 16.7% | 62.5% | |
| 38.10% | 21 | 5.1 | 713 | 11,680 | 25.0% | 46.1% | |
| 63.16% | 19 | 4.8 | 953 | 8,807 | 44.4% | 80.0% | |
| 38.89% | 18 | 5.1 | 876 | 10,456 | 22.2% | 55.6% | |
| 47.06% | 17 | 5.4 | 820 | 12,295 | 50.0% | 46.1% | |
| 62.50% | 16 | 6.2 | 1,092 | 11,216 | 62.5% | 62.5% | |
| 50.00% | 16 | 5.1 | 864 | 8,192 | 45.5% | 60.0% | |
| 40.00% | 15 | 5.7 | 928 | 11,379 | 16.7% | 55.6% | |
| 33.33% | 15 | 2.6 | 724 | 9,938 | 33.3% | 33.3% | |
| 42.86% | 14 | 5.7 | 829 | 9,712 | 57.1% | 28.6% | |
| 46.15% | 13 | 5.0 | 837 | 11,280 | 60.0% | 37.5% | |
| 69.23% | 13 | 5.1 | 898 | 10,973 | 66.7% | 70.0% | |
| 76.92% | 13 | 6.0 | 935 | 11,339 | 80.0% | 75.0% | |
| 61.54% | 13 | 5.6 | 884 | 10,601 | 75.0% | 55.6% | |
| 41.67% | 12 | 5.0 | 832 | 9,731 | 33.3% | 50.0% | |
| 50.00% | 12 | 5.2 | 647 | 6,840 | 50.0% | 50.0% | |
| 50.00% | 12 | 5.9 | 746 | 9,471 | 50.0% | 50.0% | |
| 72.73% | 11 | 6.3 | 1,135 | 13,858 | 66.7% | 75.0% | |
| 54.55% | 11 | 5.5 | 683 | 10,779 | 66.7% | 50.0% | |
| 36.36% | 11 | 4.3 | 815 | 10,464 | 50.0% | 28.6% | |
| 80.00% | 10 | 6.9 | 904 | 10,299 | 66.7% | 100.0% | |
| 50.00% | 10 | 2.8 | 653 | 9,287 | 50.0% | 50.0% | |
| 40.00% | 10 | 4.0 | 800 | 11,341 | 50.0% | 33.3% | |
| 22.22% | 9 | 5.9 | 775 | 11,531 | 0.0% | 33.3% | |
| 11.11% | 9 | 3.5 | 718 | 9,599 | 0.0% | 20.0% | |
| 77.78% | 9 | 4.9 | 967 | 11,333 | 50.0% | 85.7% | |
| 77.78% | 9 | 2.0 | 641 | 9,528 | 100.0% | 66.7% | |
| 62.50% | 8 | 6.0 | 923 | 13,018 | 66.7% | 60.0% | |
| 57.14% | 7 | 6.0 | 847 | 12,204 | 50.0% | 60.0% | |
| 42.86% | 7 | 1.3 | 585 | 8,520 | 75.0% | 0.0% | |
| 28.57% | 7 | 6.4 | 1,032 | 12,391 | 0.0% | 40.0% | |
| 71.43% | 7 | 1.4 | 707 | 9,557 | 100.0% | 60.0% | |
| 33.33% | 6 | 2.2 | 638 | 10,332 | 0.0% | 50.0% | |
| 16.67% | 6 | 5.6 | 937 | 13,962 | 0.0% | 20.0% | |
| 16.67% | 6 | 6.2 | 704 | 7,416 | 20.0% | 0.0% | |
| 83.33% | 6 | 5.1 | 1,071 | 9,253 | 66.7% | 100.0% | |
| 33.33% | 6 | 6.1 | 719 | 11,309 | 100.0% | 20.0% | |
| 66.67% | 6 | 6.2 | 1,056 | 13,859 | 0.0% | 66.7% | |
| 66.67% | 6 | 2.0 | 850 | 12,912 | 0.0% | 66.7% | |
| 20.00% | 5 | 5.7 | 850 | 11,301 | 0.0% | 33.3% | |
| 80.00% | 5 | 5.6 | 850 | 10,889 | 0.0% | 100.0% | |
| 80.00% | 5 | 6.0 | 764 | 9,268 | 66.7% | 100.0% | |
| 60.00% | 5 | 5.3 | 728 | 11,470 | 50.0% | 66.7% | |
| 80.00% | 5 | 4.8 | 783 | 10,313 | 100.0% | 50.0% | |
| 40.00% | 5 | 3.9 | 996 | 12,172 | 50.0% | 33.3% | |
| 40.00% | 5 | 7.0 | 1,290 | 11,256 | 0.0% | 66.7% | |
| 80.00% | 5 | 3.8 | 821 | 9,389 | 100.0% | 50.0% | |
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Annie vs Cassiopeia - Frequently Asked Questions
How does Annie do against Cassiopeia in League of Legends?
Annie wins the Annie vs Cassiopeia matchup with a 57.1% win rate compared to Cassiopeia's 42.9%, a 14.3 percentage point difference. This data is based on 7 recent ranked games in patch 26.14.
How does Annie do against Cassiopeia in the early game?
In the early game, Annie has the advantage against Cassiopeia with a 50.0% win rate versus 50.0%. Annie players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Annie do against Cassiopeia in the late game?
In the late game, Annie takes over the Annie vs Cassiopeia matchup with a 60.0% win rate compared to 40.0%. Annie scales better into team fights and objective contests after 25 minutes.
Who wins the Annie vs Cassiopeia matchup?
Annie wins the matchup against Cassiopeia with a 57.1% win rate in League of Legends patch 26.14. The 14.3 percentage point advantage means Annie is significantly favored in this lane matchup based on 7 games analyzed.
What is the best Annie build against Cassiopeia?
The best Annie build against Cassiopeia includes Liandry's Torment, Hextech Rocketbelt, Malignance with Swiftmarch. Check the matchup breakdown above for the full item path and build order.
What are the best Annie runes against Cassiopeia?
The best Annie runes against Cassiopeia use the Domination primary tree with Sorcery secondary. This rune setup achieves a 50.0% win rate in the Annie vs Cassiopeia matchup. See the full rune breakdown in the matchup comparison above.
Does Annie counter Cassiopeia?
Yes, Annie has a favorable matchup against Cassiopeia with a 57.1% win rate. Annie strongly counters Cassiopeia in lane based on current patch 26.14 data.
How do I play Annie against Cassiopeia?
When playing Annie against Cassiopeia, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.
