Cassiopeia - League of Legends Champion
Win Rate
48.3%
Pick Rate
0.9%

Cassiopeiavs Annie

FMage
Patch26.14
Matches491,560
LaneAll Lanes
TierAll Tiers
Last UpdatedJul 21, 2026
MethodologyData Methodology

Cassiopeia vs Annie is a decisive matchup in LoL patch 26.14. Annie wins with a 57.1% win rate (+14.3%) over Cassiopeia based on 7 games. Cassiopeia wins the early laning phase while Annie scales better into the late game. Below you'll find the best Cassiopeia build, runes, laning stats, and strategies for the Cassiopeia vs Annie matchup.

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Cassiopeia Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Cassiopeia performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Cassiopeia - 42.9% win rate in this matchup
Cassiopeia
42.9% WR
VS
Annie vs Cassiopeia matchup - 57.1% win rate
Annie
57.1% WR

Who Wins the Cassiopeia vs Annie Matchup?

Annie wins the Cassiopeia vs Annie matchup
Winner
Annie
Matches: 7
42.9%
Win Rate
57.1%
6.2
CS / min
6.0
703
DMG / min
847
12,072
Gold / game
12,204
239
Heal / min
69
487
DMG Mitigated / min
388
1.1
CC / min
0.9
50.0%
Early Game WR
50.0%
40.0%
Late Game WR
60.0%

Cassiopeia vs Annie Matchup Summary

The Cassiopeia vs Annie matchup is a decisive matchup in League of Legends ranked play. Based on 7 recent matches analyzed, Annie wins with a 57.1% win rate compared to Cassiopeia's 42.9%, giving Annie a 14.3 percentage point advantage. Game phase dynamics play a critical role here: Cassiopeia controls the early laning stage, but Annie outscales as the game goes longer. The matchup shifts dramatically depending on game length — Cassiopeia needs to press advantages before Annie reaches their power spikes, while Annie should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in sustain, where Cassiopeia leads by 270 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Annie has a strong advantage in this matchup. Cassiopeia players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Annie overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Cassiopeia vs Annie Laning Phase Breakdown

Cassiopeia wins the laning phase against Annie in League of Legends

Cassiopeia is favored during the laning phase against Annie, winning 3 out of 5 key stat categories. Cassiopeia holds advantages in farming, crowd control and sustain, making them the stronger laner in this matchup.

Farming
6.2Cassiopeia
6.0Annie
Cassiopeia and Annie farm at nearly identical rates in this matchup, with only a 0.2 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
703Cassiopeia
847Annie
Annie heavily out-damages Cassiopeia by 144 DMG/min, dominating both short trades and all-in fights. Cassiopeia should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Annie's sustained damage advantage take over.
Economy
12,072Cassiopeia
12,204Annie
Cassiopeia and Annie generate nearly equal gold per game, with just a 133 gold difference. Neither champion has a clear economic advantage, so gold leads will depend on individual play quality, kill participation, and objective contributions.
Utility
1.1Cassiopeia
0.9Annie
Both Cassiopeia and Annie provide similar amounts of crowd control (0.2s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
726Cassiopeia
456Annie
Cassiopeia vastly out-sustains Annie, healing and mitigating 270 more damage per minute. This massive durability gap means Cassiopeia can absorb significant punishment and remain in lane while Annie is forced to recall. Building grievous wounds early is essential for Annie, and focusing on burst trade patterns rather than sustained fights is critical.

Best Cassiopeia Build Against Annie

Spellslinger's Shoes is the optimal boots choice against Annie, providing the mobility and stats Cassiopeia needs most in this matchup. The top-performing core items for Cassiopeia against Annie are Rod of Ages, Liandry's Torment and Rylai's Crystal Scepter. This combination gives Cassiopeia an effective balance of damage, survivability, and utility for the matchup. This build has a 33.3% win rate across 3 games. While the overall matchup may be difficult, this item path gives Cassiopeia the best chance to compete against Annie. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Cassiopeia vs Annie matchup.

Early Game vs Late Game

Early Game
Cassiopeia
50.0%
+0.0% advantage
Cassiopeia early game win rateCassiopeia50.0%
Annie early game win rateAnnie50.0%
Late Game
Annie
60.0%
+20.0% advantage
Cassiopeia late game win rateCassiopeia40.0%
Annie late game win rateAnnie60.0%

The early game (first 15 minutes) is a toss-up between Cassiopeia and Annie, with Cassiopeia holding a razor-thin 50.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.

Annie is far superior in the late game (25+ minutes), boasting a 60.0% win rate — 20.0 points above Cassiopeia. Extended games heavily favor Annie, whose kit and scaling make them a dominant force in team fights and objective control.

The power dynamics shift as the game progresses — Cassiopeia has the edge early, but Annie gradually takes over. However, the margins are slim enough that either champion can win at any stage with the right plays. Focus on taking advantages when you have them rather than waiting for a specific game phase.

Best Cassiopeia Runes Against Annie

Sorcery rune tree - Cassiopeia primary runes vs AnnieSorcery
Deathfire Touch - best Cassiopeia rune vs AnnieManaflow Band - best Cassiopeia rune vs AnnieTranscendence - best Cassiopeia rune vs AnnieScorch - best Cassiopeia rune vs Annie
Precision rune tree - Cassiopeia secondary runes vs AnniePrecision
Coup de Grace - best Cassiopeia rune vs AnniePresence of Mind - best Cassiopeia rune vs Annie
40.0% WR

The Sorcery and Precision rune setup gives Cassiopeia the best tools to compete against Annie in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Cassiopeia matchup data for League of Legends patch 26.14. The table below shows Cassiopeia's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Cassiopeia build, runes, laning stats, and early vs late game analysis for that specific matchup.

Cassiopeia matchup win rates and stats in League of Legends patch 26.14
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
43.24%376.687710,50526.7%54.5%
50.00%305.986510,45845.5%52.6%
46.67%306.576610,53142.9%50.0%
48.28%296.596411,07356.3%38.5%
29.63%276.584211,42727.3%31.3%
56.52%235.565010,05440.0%69.2%
54.55%226.371710,75233.3%69.2%
66.67%216.37939,59277.8%58.3%
77.78%186.483212,09887.5%70.0%
41.18%176.285910,9870.0%63.6%
47.06%176.891610,67333.3%62.5%
58.82%176.888311,90250.0%66.7%
58.82%176.586211,85957.1%60.0%
41.18%176.169610,42414.3%60.0%
68.75%166.672512,820100.0%61.5%
25.00%166.664410,61922.2%28.6%
60.00%156.786412,06180.0%50.0%
28.57%145.294711,21520.0%33.3%
64.29%146.393715,587100.0%58.3%
30.77%137.266010,23833.3%28.6%
46.15%136.388711,89860.0%37.5%
38.46%136.074911,49325.0%44.4%
58.33%126.079110,35466.7%50.0%
18.18%116.481613,1240.0%20.0%
36.36%116.579511,10620.0%50.0%
45.45%116.469811,23660.0%33.3%
20.00%106.471010,02220.0%20.0%
77.78%96.196912,63266.7%83.3%
22.22%96.095414,9540.0%28.6%
77.78%97.08358,42185.7%50.0%
44.44%96.593012,24866.7%33.3%
66.67%96.81,03312,45566.7%66.7%
77.78%96.086413,088100.0%71.4%
37.50%86.696514,89433.3%40.0%
37.50%86.473911,89950.0%33.3%
57.14%77.41,13111,888100.0%40.0%
71.43%76.891011,39175.0%66.7%
42.86%76.791011,03033.3%50.0%
42.86%75.26188,80525.0%66.7%
42.86%77.297413,0710.0%75.0%
85.71%76.492914,88250.0%100.0%
0.00%75.96439,8530.0%0.0%
42.86%76.385110,5390.0%75.0%
85.71%76.81,02112,042100.0%66.7%
42.86%76.483311,76233.3%50.0%
57.14%76.39008,83866.7%50.0%
42.86%77.773510,61850.0%33.3%
57.14%75.68649,854100.0%0.0%
42.86%76.270312,07250.0%40.0%
57.14%76.77769,86875.0%33.3%
33.33%66.17299,1760.0%50.0%
16.67%64.871711,9290.0%20.0%
33.33%66.26488,58266.7%0.0%
33.33%66.35988,92025.0%50.0%
50.00%66.694713,80550.0%50.0%
16.67%66.07129,87933.3%0.0%
50.00%66.083412,8820.0%75.0%
33.33%66.495213,2040.0%40.0%
50.00%67.21,0929,78425.0%100.0%
20.00%56.072010,7890.0%33.3%
60.00%57.21,06212,03050.0%66.7%
40.00%56.569212,20150.0%33.3%
80.00%58.293011,461100.0%50.0%

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Cassiopeia vs Annie - Frequently Asked Questions

How does Cassiopeia do against Annie in League of Legends?

Annie wins the Cassiopeia vs Annie matchup with a 57.1% win rate compared to Cassiopeia's 42.9%, a 14.3 percentage point difference. This data is based on 7 recent ranked games in patch 26.14.

How does Cassiopeia do against Annie in the early game?

In the early game, Cassiopeia has the advantage against Annie with a 50.0% win rate versus 50.0%. Cassiopeia players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Cassiopeia do against Annie in the late game?

In the late game, Annie takes over the Cassiopeia vs Annie matchup with a 60.0% win rate compared to 40.0%. Annie scales better into team fights and objective contests after 25 minutes.

Who wins the Cassiopeia vs Annie matchup?

Annie wins the matchup against Cassiopeia with a 57.1% win rate in League of Legends patch 26.14. The 14.3 percentage point advantage means Annie is significantly favored in this lane matchup based on 7 games analyzed.

What is the best Cassiopeia build against Annie?

The best Cassiopeia build against Annie includes Rod of Ages, Liandry's Torment, Rylai's Crystal Scepter with Spellslinger's Shoes. This build achieves a 33.3% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Cassiopeia runes against Annie?

The best Cassiopeia runes against Annie use the Sorcery primary tree with Precision secondary. This rune setup achieves a 40.0% win rate in the Cassiopeia vs Annie matchup. See the full rune breakdown in the matchup comparison above.

Does Cassiopeia counter Annie?

No, Cassiopeia struggles against Annie with only a 42.9% win rate. Annie has the advantage in this matchup. Cassiopeia players should focus on safe farming and avoiding extended trades to minimize Annie's lead.

How do I play Cassiopeia against Annie?

When playing Cassiopeia against Annie, play cautiously and avoid Annie's power spikes. Look for jungle assistance and team-dependent plays since Annie has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.