Cassiopeiavs Annie
Cassiopeia vs Annie is a decisive matchup in LoL patch 26.9. Annie wins with a 63.6% win rate (+27.3%) over Cassiopeia based on 11 games. Cassiopeia wins the early laning phase while Annie scales better into the late game. Below you'll find the best Cassiopeia build, runes, laning stats, and strategies for the Cassiopeia vs Annie matchup.
Cassiopeia Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Cassiopeia performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Annie(36.4%)Who Wins the Cassiopeia vs Annie Matchup?
Cassiopeia vs Annie Matchup Summary
The Cassiopeia vs Annie matchup is a decisive matchup in League of Legends ranked play. Based on 11 recent matches analyzed, Annie wins with a 63.6% win rate compared to Cassiopeia's 36.4%, giving Annie a 27.3 percentage point advantage. Game phase dynamics play a critical role here: Cassiopeia controls the early laning stage, but Annie outscales as the game goes longer. The matchup shifts dramatically depending on game length — Cassiopeia needs to press advantages before Annie reaches their power spikes, while Annie should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in sustain, where Cassiopeia leads by 373 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Annie has a strong advantage in this matchup. Cassiopeia players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Annie overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Cassiopeia vs Annie Laning Phase Breakdown
Annie is favored during the laning phase against Cassiopeia, winning 3 out of 5 key stat categories. Annie holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.
Best Cassiopeia Build Against Annie
Swiftmarch is the optimal boots choice against Annie, providing the mobility and stats Cassiopeia needs most in this matchup. The top-performing core items for Cassiopeia against Annie are Liandry's Torment, Rylai's Crystal Scepter and Seraph's Embrace. This combination gives Cassiopeia an effective balance of damage, survivability, and utility for the matchup. This build has a 25.0% win rate across 4 games. While the overall matchup may be difficult, this item path gives Cassiopeia the best chance to compete against Annie. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Cassiopeia vs Annie matchup.
Early Game vs Late Game
Cassiopeia66.7%Annie33.3%Cassiopeia25.0%Annie75.0%Cassiopeia dominates the early game (first 15 minutes) with a commanding 66.7% win rate — a 33.3 percentage point lead over Annie. This lopsided early game means Cassiopeia can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Annie is far superior in the late game (25+ minutes), boasting a 75.0% win rate — 50.0 points above Cassiopeia. Extended games heavily favor Annie, whose kit and scaling make them a dominant force in team fights and objective control.
This matchup features a dramatic power shift: Cassiopeia must aggressively press their early advantage and close out the game before Annie reaches their scaling breakpoints. If Annie survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.
Best Cassiopeia Runes Against Annie
Sorcery
Precision
The Sorcery and Precision rune setup gives Cassiopeia the best tools to compete against Annie in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.
Cassiopeia matchup data for League of Legends patch 26.9. The table below shows Cassiopeia's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Cassiopeia build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 47.37% | 38 | 6.8 | 724 | 11,436 | 50.0% | 44.4% | |
| 48.48% | 33 | 6.5 | 801 | 12,214 | 50.0% | 47.1% | |
| 46.43% | 28 | 6.5 | 709 | 11,643 | 58.3% | 37.5% | |
| 48.15% | 27 | 6.9 | 827 | 11,849 | 54.5% | 43.8% | |
| 53.85% | 26 | 6.8 | 796 | 12,651 | 62.5% | 50.0% | |
| 45.83% | 24 | 6.4 | 873 | 12,400 | 50.0% | 43.8% | |
| 59.09% | 22 | 6.9 | 957 | 10,000 | 64.3% | 50.0% | |
| 47.62% | 21 | 6.5 | 918 | 12,316 | 50.0% | 46.1% | |
| 42.11% | 19 | 6.4 | 873 | 11,643 | 77.8% | 10.0% | |
| 36.84% | 19 | 6.9 | 790 | 13,546 | 20.0% | 42.9% | |
| 42.11% | 19 | 7.1 | 839 | 11,347 | 38.5% | 50.0% | |
| 57.89% | 19 | 7.0 | 1,117 | 10,299 | 58.3% | 57.1% | |
| 62.50% | 16 | 7.6 | 917 | 12,350 | 80.0% | 33.3% | |
| 40.00% | 15 | 6.8 | 733 | 9,766 | 14.3% | 62.5% | |
| 33.33% | 15 | 6.7 | 714 | 10,848 | 22.2% | 50.0% | |
| 46.67% | 15 | 6.9 | 873 | 12,407 | 62.5% | 28.6% | |
| 60.00% | 15 | 5.7 | 923 | 10,356 | 50.0% | 66.7% | |
| 53.33% | 15 | 6.3 | 853 | 12,674 | 57.1% | 50.0% | |
| 46.67% | 15 | 6.4 | 690 | 10,335 | 55.6% | 33.3% | |
| 64.29% | 14 | 6.7 | 916 | 11,984 | 50.0% | 75.0% | |
| 46.15% | 13 | 5.8 | 727 | 11,454 | 50.0% | 44.4% | |
| 50.00% | 12 | 6.7 | 857 | 10,805 | 57.1% | 40.0% | |
| 41.67% | 12 | 6.2 | 951 | 12,814 | 40.0% | 42.9% | |
| 58.33% | 12 | 6.9 | 833 | 11,580 | 100.0% | 37.5% | |
| 41.67% | 12 | 6.2 | 831 | 11,581 | 50.0% | 33.3% | |
| 50.00% | 12 | 5.8 | 820 | 12,552 | 33.3% | 55.6% | |
| 41.67% | 12 | 7.4 | 916 | 11,832 | 42.9% | 40.0% | |
| 36.36% | 11 | 7.4 | 863 | 12,272 | 33.3% | 40.0% | |
| 63.64% | 11 | 6.5 | 1,009 | 14,340 | 66.7% | 60.0% | |
| 54.55% | 11 | 5.7 | 721 | 11,869 | 40.0% | 66.7% | |
| 72.73% | 11 | 7.0 | 1,129 | 13,391 | 75.0% | 71.4% | |
| 36.36% | 11 | 6.4 | 820 | 12,003 | 66.7% | 25.0% | |
| 40.00% | 10 | 6.5 | 712 | 9,624 | 42.9% | 33.3% | |
| 50.00% | 10 | 6.8 | 1,216 | 13,824 | 66.7% | 42.9% | |
| 20.00% | 10 | 6.3 | 990 | 11,552 | 33.3% | 0.0% | |
| 40.00% | 10 | 6.6 | 1,013 | 11,863 | 66.7% | 0.0% | |
| 50.00% | 10 | 6.0 | 789 | 12,480 | 100.0% | 37.5% | |
| 55.56% | 9 | 5.6 | 695 | 10,379 | 50.0% | 57.1% | |
| 44.44% | 9 | 6.5 | 1,063 | 15,033 | 50.0% | 42.9% | |
| 55.56% | 9 | 7.4 | 860 | 11,787 | 50.0% | 60.0% | |
| 66.67% | 9 | 6.8 | 854 | 12,062 | 100.0% | 40.0% | |
| 62.50% | 8 | 7.1 | 896 | 13,348 | 60.0% | 66.7% | |
| 87.50% | 8 | 5.9 | 1,023 | 13,022 | 100.0% | 80.0% | |
| 37.50% | 8 | 6.8 | 898 | 11,712 | 75.0% | 0.0% | |
| 75.00% | 8 | 6.8 | 684 | 11,301 | 100.0% | 66.7% | |
| 50.00% | 8 | 6.2 | 823 | 11,105 | 50.0% | 50.0% | |
| 57.14% | 7 | 6.3 | 638 | 8,468 | 60.0% | 50.0% | |
| 57.14% | 7 | 7.0 | 874 | 13,149 | 66.7% | 50.0% | |
| 57.14% | 7 | 6.8 | 890 | 12,765 | 100.0% | 40.0% | |
| 42.86% | 7 | 6.4 | 829 | 10,133 | 40.0% | 50.0% | |
| 71.43% | 7 | 6.1 | 697 | 11,111 | 60.0% | 100.0% | |
| 57.14% | 7 | 6.2 | 836 | 11,179 | 50.0% | 66.7% | |
| 33.33% | 6 | 6.0 | 616 | 12,102 | 0.0% | 40.0% | |
| 50.00% | 6 | 5.5 | 962 | 15,454 | 0.0% | 50.0% | |
| 83.33% | 6 | 7.3 | 987 | 13,178 | 50.0% | 100.0% | |
| 20.00% | 5 | 7.1 | 907 | 12,365 | 100.0% | 0.0% | |
| 20.00% | 5 | 6.9 | 1,081 | 9,794 | 25.0% | 0.0% | |
| 60.00% | 5 | 6.6 | 958 | 17,062 | 0.0% | 60.0% | |
| 40.00% | 5 | 5.0 | 924 | 11,058 | 100.0% | 25.0% | |
| 40.00% | 5 | 5.6 | 894 | 11,588 | 33.3% | 50.0% | |
| 40.00% | 5 | 7.6 | 583 | 10,358 | 66.7% | 0.0% | |
| 60.00% | 5 | 6.0 | 662 | 7,572 | 50.0% | 100.0% | |
| 20.00% | 5 | 6.4 | 816 | 11,448 | 50.0% | 0.0% | |
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Cassiopeia vs Annie - Frequently Asked Questions
How does Cassiopeia do against Annie in League of Legends?
Annie wins the Cassiopeia vs Annie matchup with a 63.6% win rate compared to Cassiopeia's 36.4%, a 27.3 percentage point difference. This data is based on 11 recent ranked games in patch 26.9.
How does Cassiopeia do against Annie in the early game?
In the early game, Cassiopeia has the advantage against Annie with a 66.7% win rate versus 33.3%. Cassiopeia players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Cassiopeia do against Annie in the late game?
In the late game, Annie takes over the Cassiopeia vs Annie matchup with a 75.0% win rate compared to 25.0%. Annie scales better into team fights and objective contests after 25 minutes.
Who wins the Cassiopeia vs Annie matchup?
Annie wins the matchup against Cassiopeia with a 63.6% win rate in League of Legends patch 26.9. The 27.3 percentage point advantage means Annie is significantly favored in this lane matchup based on 11 games analyzed.
What is the best Cassiopeia build against Annie?
The best Cassiopeia build against Annie includes Liandry's Torment, Rylai's Crystal Scepter, Seraph's Embrace with Swiftmarch. This build achieves a 25.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.
What are the best Cassiopeia runes against Annie?
The best Cassiopeia runes against Annie use the Sorcery primary tree with Precision secondary. This rune setup achieves a 100.0% win rate in the Cassiopeia vs Annie matchup. See the full rune breakdown in the matchup comparison above.
Does Cassiopeia counter Annie?
No, Cassiopeia struggles against Annie with only a 36.4% win rate. Annie has the advantage in this matchup. Cassiopeia players should focus on safe farming and avoiding extended trades to minimize Annie's lead.
How do I play Cassiopeia against Annie?
When playing Cassiopeia against Annie, play cautiously and avoid Annie's power spikes. Look for jungle assistance and team-dependent plays since Annie has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.