Annie - League of Legends Champion
Win Rate
50.0%
Pick Rate
1.4%

Annievs Karma

CMageSupport
Patch26.7
Matches949,984
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 20, 2026
MethodologyData Methodology

Annie vs Karma is a decisive matchup in LoL patch 26.7. Karma wins with a 66.7% win rate (+33.3%) over Annie based on 12 games. Karma holds the advantage in both the early and late game. Below you'll find the best Annie build, runes, laning stats, and strategies for the Annie vs Karma matchup.

Annie Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Annie performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Karma - 33.3% win rateKarma(33.3%)
Annie - 33.3% win rate in this matchup
Annie
33.3% WR
VS
Karma vs Annie matchup - 66.7% win rate
Karma
66.7% WR

Who Wins the Annie vs Karma Matchup?

Karma wins the Annie vs Karma matchup
Winner
Karma
Matches: 12
33.3%
Win Rate
66.7%
1.7
CS / min
1.7
549
DMG / min
362
8,223
Gold / game
8,499
67
Heal / min
218
326
DMG Mitigated / min
421
1.2
CC / min
0.9
33.3%
Early Game WR
66.7%
33.3%
Late Game WR
66.7%

Annie vs Karma Matchup Summary

The Annie vs Karma matchup is a decisive matchup in League of Legends ranked play. Based on 12 recent matches analyzed, Karma wins with a 66.7% win rate compared to Annie's 33.3%, giving Karma a 33.3 percentage point advantage. Karma dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Annie players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Karma leads by 246 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Karma has a strong advantage in this matchup. Annie players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Karma overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Annie vs Karma Laning Phase Breakdown

Annie wins the laning phase against Karma in League of Legends

Annie is favored during the laning phase against Karma, winning 3 out of 5 key stat categories. Annie holds advantages in farming, damage and crowd control, making them the stronger laner in this matchup.

Farming
1.7Annie
1.7Karma
Annie and Karma farm at nearly identical rates in this matchup, with only a 0.0 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
549Annie
362Karma
Annie heavily out-damages Karma by 187 DMG/min, dominating both short trades and all-in fights. Karma should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Annie's sustained damage advantage take over.
Economy
8,223Annie
8,499Karma
Annie and Karma generate nearly equal gold per game, with just a 276 gold difference. Neither champion has a clear economic advantage, so gold leads will depend on individual play quality, kill participation, and objective contributions.
Utility
1.2Annie
0.9Karma
Both Annie and Karma provide similar amounts of crowd control (0.3s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
393Annie
639Karma
Karma vastly out-sustains Annie, healing and mitigating 246 more damage per minute. This massive durability gap means Karma can absorb significant punishment and remain in lane while Annie is forced to recall. Building grievous wounds early is essential for Annie, and focusing on burst trade patterns rather than sustained fights is critical.

Best Annie Build Against Karma

Ionian Boots of Lucidity is the optimal boots choice against Karma, providing the mobility and stats Annie needs most in this matchup. The top-performing core items for Annie against Karma are Liandry's Torment, Morellonomicon and Rylai's Crystal Scepter. This combination gives Annie an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Karma. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Annie vs Karma matchup.

Early Game vs Late Game

Early Game
Karma
66.7%
+33.3% advantage
Annie early game win rateAnnie33.3%
Karma early game win rateKarma66.7%
Late Game
Karma
66.7%
+33.3% advantage
Annie late game win rateAnnie33.3%
Karma late game win rateKarma66.7%

Karma dominates the early game (first 15 minutes) with a commanding 66.7% win rate — a 33.3 percentage point lead over Annie. This lopsided early game means Karma can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Karma is far superior in the late game (25+ minutes), boasting a 66.7% win rate — 33.3 points above Annie. Extended games heavily favor Karma, whose kit and scaling make them a dominant force in team fights and objective control.

Karma holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Annie players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Annie Runes Against Karma

Domination rune tree - Annie primary runes vs KarmaDomination
Dark Harvest - best Annie rune vs KarmaCheap Shot - best Annie rune vs KarmaGrisly Mementos - best Annie rune vs KarmaUltimate Hunter - best Annie rune vs Karma
Inspiration rune tree - Annie secondary runes vs KarmaInspiration
Cash Back - best Annie rune vs KarmaCosmic Insight - best Annie rune vs Karma
100.0% WR

The Domination and Inspiration rune setup gives Annie the best tools to compete against Karma in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Annie matchup data for League of Legends patch 26.7. The table below shows Annie's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Annie build, runes, laning stats, and early vs late game analysis for that specific matchup.

Annie matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
45.98%876.094612,03938.5%52.1%
42.86%845.986911,27542.5%43.2%
46.00%505.580410,85652.2%40.7%
60.00%505.596211,12952.2%66.7%
55.00%406.093311,39656.5%52.9%
43.59%395.791511,94221.4%56.0%
45.95%375.886912,18741.7%48.0%
55.56%365.384211,00158.8%52.6%
54.29%355.087211,89464.3%47.6%
47.06%345.889510,88735.0%64.3%
37.50%325.796611,72316.7%50.0%
43.33%305.978810,94758.3%33.3%
46.67%305.484012,03137.5%50.0%
44.83%295.871310,38826.7%64.3%
71.43%285.999912,33466.7%76.9%
46.43%285.286310,62838.5%53.3%
48.15%274.282911,46650.0%47.4%
46.15%266.093111,78455.6%41.2%
52.00%256.076910,39233.3%69.2%
33.33%246.387510,52545.5%23.1%
43.48%235.894212,20030.0%53.9%
50.00%225.596811,66666.7%38.5%
30.00%205.582410,34033.3%25.0%
45.00%206.390710,00846.1%42.9%
47.37%195.483011,54312.5%72.7%
33.33%185.21,02611,54730.0%37.5%
70.59%175.875611,05275.0%66.7%
37.50%163.68529,59312.5%62.5%
43.75%166.488710,48150.0%33.3%
37.50%165.782811,50060.0%27.3%
53.33%151.46229,27950.0%55.6%
66.67%156.397811,67170.0%60.0%
61.54%135.372811,40175.0%55.6%
33.33%121.75498,22333.3%33.3%
50.00%121.66919,77057.1%40.0%
41.67%125.194712,03860.0%28.6%
54.55%112.15998,84542.9%75.0%
90.91%114.08319,13785.7%100.0%
45.45%115.51,06912,73325.0%57.1%
70.00%106.588311,780100.0%25.0%
40.00%102.27229,90140.0%40.0%
60.00%105.61,09311,46860.0%60.0%
50.00%106.11,01511,96260.0%40.0%
44.44%96.889112,01120.0%75.0%
33.33%95.29477,19850.0%0.0%
66.67%94.775710,24450.0%80.0%
75.00%81.87039,69180.0%66.7%
62.50%82.977911,22366.7%60.0%
37.50%82.66579,5510.0%50.0%
62.50%81.771711,07660.0%66.7%
85.71%75.694313,370100.0%80.0%
0.00%74.85678,1960.0%0.0%
57.14%75.684711,61166.7%50.0%
71.43%73.56829,60533.3%100.0%
42.86%76.38668,90325.0%66.7%
42.86%75.994313,302100.0%33.3%
85.71%75.195912,52950.0%100.0%
50.00%65.697412,5110.0%60.0%
50.00%64.57117,57525.0%100.0%
66.67%61.251210,7010.0%80.0%
33.33%65.492913,7750.0%40.0%
50.00%65.41,19514,59350.0%50.0%
60.00%54.690112,9020.0%75.0%
60.00%55.01,01012,9840.0%60.0%
20.00%52.35038,22725.0%0.0%

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Annie vs Karma - Frequently Asked Questions

How does Annie do against Karma in League of Legends?

Karma wins the Annie vs Karma matchup with a 66.7% win rate compared to Annie's 33.3%, a 33.3 percentage point difference. This data is based on 12 recent ranked games in patch 26.7.

How does Annie do against Karma in the early game?

In the early game, Karma has the advantage against Annie with a 66.7% win rate versus 33.3%. Karma players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Annie do against Karma in the late game?

In the late game, Karma takes over the Annie vs Karma matchup with a 66.7% win rate compared to 33.3%. Karma scales better into team fights and objective contests after 25 minutes.

Who wins the Annie vs Karma matchup?

Karma wins the matchup against Annie with a 66.7% win rate in League of Legends patch 26.7. The 33.3 percentage point advantage means Karma is significantly favored in this lane matchup based on 12 games analyzed.

What is the best Annie build against Karma?

The best Annie build against Karma includes Liandry's Torment, Morellonomicon, Rylai's Crystal Scepter with Ionian Boots of Lucidity. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Annie runes against Karma?

The best Annie runes against Karma use the Domination primary tree with Inspiration secondary. This rune setup achieves a 100.0% win rate in the Annie vs Karma matchup. See the full rune breakdown in the matchup comparison above.

Does Annie counter Karma?

No, Annie struggles against Karma with only a 33.3% win rate. Karma has the advantage in this matchup. Annie players should focus on safe farming and avoiding extended trades to minimize Karma's lead.

How do I play Annie against Karma?

When playing Annie against Karma, play cautiously and avoid Karma's power spikes. Look for jungle assistance and team-dependent plays since Karma has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.