Annie - League of Legends Champion
Win Rate
50.0%
Pick Rate
1.4%

Annievs Senna

CMageSupport
Patch26.7
Matches949,984
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 21, 2026
MethodologyData Methodology

Annie vs Senna is a decisive matchup in LoL patch 26.7. Senna wins with a 60.0% win rate (+20.0%) over Annie based on 10 games. Senna holds the advantage in both the early and late game. Below you'll find the best Annie build, runes, laning stats, and strategies for the Annie vs Senna matchup.

Annie Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Annie performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Senna - 40.0% win rateSenna(40.0%)
Annie - 40.0% win rate in this matchup
Annie
40.0% WR
VS
Senna vs Annie matchup - 60.0% win rate
Senna
60.0% WR

Who Wins the Annie vs Senna Matchup?

Senna wins the Annie vs Senna matchup
Winner
Senna
Matches: 10
40.0%
Win Rate
60.0%
2.2
CS / min
2.3
722
DMG / min
562
9,901
Gold / game
10,701
97
Heal / min
536
405
DMG Mitigated / min
302
1.2
CC / min
1.4
40.0%
Early Game WR
60.0%
40.0%
Late Game WR
60.0%

Annie vs Senna Matchup Summary

The Annie vs Senna matchup is a decisive matchup in League of Legends ranked play. Based on 10 recent matches analyzed, Senna wins with a 60.0% win rate compared to Annie's 40.0%, giving Senna a 20.0 percentage point advantage. Senna dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Annie players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Senna leads by 336 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Senna has a strong advantage in this matchup. Annie players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Senna overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Annie vs Senna Laning Phase Breakdown

Senna wins the laning phase against Annie in League of Legends

Senna is favored during the laning phase against Annie, winning 4 out of 5 key stat categories. Senna holds advantages in farming, gold income, crowd control and sustain, making them the stronger laner in this matchup.

Farming
2.2Annie
2.3Senna
Annie and Senna farm at nearly identical rates in this matchup, with only a 0.0 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
722Annie
562Senna
Annie heavily out-damages Senna by 160 DMG/min, dominating both short trades and all-in fights. Senna should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Annie's sustained damage advantage take over.
Economy
9,901Annie
10,701Senna
Senna generates a commanding 800 more gold per game than Annie. This substantial economic advantage means Senna consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Annie should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
1.2Annie
1.4Senna
Both Annie and Senna provide similar amounts of crowd control (0.1s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
501Annie
837Senna
Senna vastly out-sustains Annie, healing and mitigating 336 more damage per minute. This massive durability gap means Senna can absorb significant punishment and remain in lane while Annie is forced to recall. Building grievous wounds early is essential for Annie, and focusing on burst trade patterns rather than sustained fights is critical.

Best Annie Build Against Senna

Spellslinger's Shoes is the optimal boots choice against Senna, providing the mobility and stats Annie needs most in this matchup. The top-performing core items for Annie against Senna are Stormsurge, Shadowflame and Malignance. This combination gives Annie an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 2 games — well above average and making it the top item path against Senna. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Annie vs Senna matchup.

Early Game vs Late Game

Early Game
Senna
60.0%
+20.0% advantage
Annie early game win rateAnnie40.0%
Senna early game win rateSenna60.0%
Late Game
Senna
60.0%
+20.0% advantage
Annie late game win rateAnnie40.0%
Senna late game win rateSenna60.0%

Senna dominates the early game (first 15 minutes) with a commanding 60.0% win rate — a 20.0 percentage point lead over Annie. This lopsided early game means Senna can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Senna is far superior in the late game (25+ minutes), boasting a 60.0% win rate — 20.0 points above Annie. Extended games heavily favor Senna, whose kit and scaling make them a dominant force in team fights and objective control.

Senna holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Annie players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Annie Runes Against Senna

Domination rune tree - Annie primary runes vs SennaDomination
Electrocute - best Annie rune vs SennaCheap Shot - best Annie rune vs SennaGrisly Mementos - best Annie rune vs SennaRelentless Hunter - best Annie rune vs Senna
Sorcery rune tree - Annie secondary runes vs SennaSorcery
Axiom Arcanist - best Annie rune vs SennaAbsolute Focus - best Annie rune vs Senna
100.0% WR

The Domination and Sorcery rune setup gives Annie the best tools to compete against Senna in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Annie matchup data for League of Legends patch 26.7. The table below shows Annie's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Annie build, runes, laning stats, and early vs late game analysis for that specific matchup.

Annie matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
45.98%876.094612,03938.5%52.1%
42.86%845.986911,27542.5%43.2%
46.00%505.580410,85652.2%40.7%
60.00%505.596211,12952.2%66.7%
55.00%406.093311,39656.5%52.9%
43.59%395.791511,94221.4%56.0%
45.95%375.886912,18741.7%48.0%
55.56%365.384211,00158.8%52.6%
54.29%355.087211,89464.3%47.6%
47.06%345.889510,88735.0%64.3%
37.50%325.796611,72316.7%50.0%
43.33%305.978810,94758.3%33.3%
46.67%305.484012,03137.5%50.0%
44.83%295.871310,38826.7%64.3%
71.43%285.999912,33466.7%76.9%
46.43%285.286310,62838.5%53.3%
48.15%274.282911,46650.0%47.4%
46.15%266.093111,78455.6%41.2%
52.00%256.076910,39233.3%69.2%
33.33%246.387510,52545.5%23.1%
43.48%235.894212,20030.0%53.9%
50.00%225.596811,66666.7%38.5%
30.00%205.582410,34033.3%25.0%
45.00%206.390710,00846.1%42.9%
47.37%195.483011,54312.5%72.7%
33.33%185.21,02611,54730.0%37.5%
70.59%175.875611,05275.0%66.7%
37.50%163.68529,59312.5%62.5%
43.75%166.488710,48150.0%33.3%
37.50%165.782811,50060.0%27.3%
53.33%151.46229,27950.0%55.6%
66.67%156.397811,67170.0%60.0%
61.54%135.372811,40175.0%55.6%
33.33%121.75498,22333.3%33.3%
50.00%121.66919,77057.1%40.0%
41.67%125.194712,03860.0%28.6%
54.55%112.15998,84542.9%75.0%
90.91%114.08319,13785.7%100.0%
45.45%115.51,06912,73325.0%57.1%
70.00%106.588311,780100.0%25.0%
40.00%102.27229,90140.0%40.0%
60.00%105.61,09311,46860.0%60.0%
50.00%106.11,01511,96260.0%40.0%
44.44%96.889112,01120.0%75.0%
33.33%95.29477,19850.0%0.0%
66.67%94.775710,24450.0%80.0%
75.00%81.87039,69180.0%66.7%
62.50%82.977911,22366.7%60.0%
37.50%82.66579,5510.0%50.0%
62.50%81.771711,07660.0%66.7%
85.71%75.694313,370100.0%80.0%
0.00%74.85678,1960.0%0.0%
57.14%75.684711,61166.7%50.0%
71.43%73.56829,60533.3%100.0%
42.86%76.38668,90325.0%66.7%
42.86%75.994313,302100.0%33.3%
85.71%75.195912,52950.0%100.0%
50.00%65.697412,5110.0%60.0%
50.00%64.57117,57525.0%100.0%
66.67%61.251210,7010.0%80.0%
33.33%65.492913,7750.0%40.0%
50.00%65.41,19514,59350.0%50.0%
60.00%54.690112,9020.0%75.0%
60.00%55.01,01012,9840.0%60.0%
20.00%52.35038,22725.0%0.0%

Get the MetaBot Desktop App

Level up your gameplay with real-time overlays, automatic game detection, and instant stats — all on your desktop.

In-game overlaysAuto game detectionMulti-game supportPersonal dashboard
Download NowFree download
🔍

Help us maintain accuracy! If you notice incorrect stats, missing data, or any issues, your feedback directly improves the quality of our data for the entire community.

Report an Issue

Annie vs Senna - Frequently Asked Questions

How does Annie do against Senna in League of Legends?

Senna wins the Annie vs Senna matchup with a 60.0% win rate compared to Annie's 40.0%, a 20.0 percentage point difference. This data is based on 10 recent ranked games in patch 26.7.

How does Annie do against Senna in the early game?

In the early game, Senna has the advantage against Annie with a 60.0% win rate versus 40.0%. Senna players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Annie do against Senna in the late game?

In the late game, Senna takes over the Annie vs Senna matchup with a 60.0% win rate compared to 40.0%. Senna scales better into team fights and objective contests after 25 minutes.

Who wins the Annie vs Senna matchup?

Senna wins the matchup against Annie with a 60.0% win rate in League of Legends patch 26.7. The 20.0 percentage point advantage means Senna is significantly favored in this lane matchup based on 10 games analyzed.

What is the best Annie build against Senna?

The best Annie build against Senna includes Stormsurge, Shadowflame, Malignance with Spellslinger's Shoes. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Annie runes against Senna?

The best Annie runes against Senna use the Domination primary tree with Sorcery secondary. This rune setup achieves a 100.0% win rate in the Annie vs Senna matchup. See the full rune breakdown in the matchup comparison above.

Does Annie counter Senna?

No, Annie struggles against Senna with only a 40.0% win rate. Senna has the advantage in this matchup. Annie players should focus on safe farming and avoiding extended trades to minimize Senna's lead.

How do I play Annie against Senna?

When playing Annie against Senna, play cautiously and avoid Senna's power spikes. Look for jungle assistance and team-dependent plays since Senna has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.