Annie - League of Legends Champion
Win Rate
52.0%
Pick Rate
1.3%

Annievs Senna

SMageSupport
Patch26.14
Matches491,560
LaneAll Lanes
TierAll Tiers
Last UpdatedJul 21, 2026
MethodologyData Methodology

Annie vs Senna is a very close matchup in LoL patch 26.14. Annie wins with a 50.0% win rate (+0.0%) over Senna based on 10 games. Annie holds the advantage in both the early and late game. Below you'll find the best Annie build, runes, laning stats, and strategies for the Annie vs Senna matchup.

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Annie Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Annie performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Annie - 50.0% win rate in this matchup
Annie
50.0% WR
VS
Senna vs Annie matchup - 50.0% win rate
Senna
50.0% WR

Who Wins the Annie vs Senna Matchup?

Annie wins the Annie vs Senna matchup
Winner
Annie
Matches: 10
50.0%
Win Rate
50.0%
2.8
CS / min
3.5
653
DMG / min
864
9,287
Gold / game
11,193
51
Heal / min
377
336
DMG Mitigated / min
350
1.0
CC / min
1.4
50.0%
Early Game WR
50.0%
50.0%
Late Game WR
50.0%

Annie vs Senna Matchup Summary

The Annie vs Senna matchup is essentially a coin-flip matchup in League of Legends ranked play. Based on 10 recent matches analyzed, Annie wins with a 50.0% win rate compared to Senna's 50.0%, giving Annie a 0.0 percentage point advantage. Annie holds a slight edge in both the early and late game, but the margins are thin enough that individual skill and jungle attention will often determine the outcome. Senna can still find windows through outplays and team coordination. The most significant statistical gap is in sustain, where Senna leads by 340 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Annie has a statistical edge, but the margin is close enough that respecting Senna's strengths is important. Trade when cooldowns are favorable, track the enemy jungler, and build toward your strongest item spikes to convert the slight advantage into a decisive lead. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Annie vs Senna Laning Phase Breakdown

Senna wins the laning phase against Annie in League of Legends

Senna is favored during the laning phase against Annie, winning 5 out of 5 key stat categories. Senna holds advantages in farming, damage, gold income, crowd control and sustain, making them the stronger laner in this matchup.

Farming
2.8Annie
3.5Senna
Senna edges out Annie by 0.8 CS per minute — a moderate farming advantage that adds up to roughly 12 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Senna.
Damage
653Annie
864Senna
Senna heavily out-damages Annie by 211 DMG/min, dominating both short trades and all-in fights. Annie should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Senna's sustained damage advantage take over.
Economy
9,287Annie
11,193Senna
Senna generates a commanding 1,906 more gold per game than Annie. This substantial economic advantage means Senna consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Annie should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
1.0Annie
1.4Senna
Senna provides 0.3 seconds more crowd control per minute than Annie, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Senna coordinate with their jungler and control the pace of skirmishes.
Sustain
387Annie
726Senna
Senna vastly out-sustains Annie, healing and mitigating 340 more damage per minute. This massive durability gap means Senna can absorb significant punishment and remain in lane while Annie is forced to recall. Building grievous wounds early is essential for Annie, and focusing on burst trade patterns rather than sustained fights is critical.

Best Annie Build Against Senna

Ionian Boots of Lucidity is the optimal boots choice against Senna, providing the mobility and stats Annie needs most in this matchup. The top-performing core items for Annie against Senna are Liandry's Torment, Malignance and Rylai's Crystal Scepter. This combination gives Annie an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Annie vs Senna matchup.

Early Game vs Late Game

Early Game
Annie
50.0%
+0.0% advantage
Annie early game win rateAnnie50.0%
Senna early game win rateSenna50.0%
Late Game
Annie
50.0%
+0.0% advantage
Annie late game win rateAnnie50.0%
Senna late game win rateSenna50.0%

The early game (first 15 minutes) is a toss-up between Annie and Senna, with Annie holding a razor-thin 50.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.

Late game (25+ minutes) is equally balanced, with Annie at 50.0% win rate — only 0.0 points ahead of Senna. Team fight execution and macro play determine the winner at this stage, not champion matchup advantage.

This matchup is remarkably even at every stage of the game. Neither Annie nor Senna has a phase-specific advantage, making this a pure skill matchup where individual mechanics, decision-making, and team coordination determine the outcome.

Best Annie Runes Against Senna

Domination rune tree - Annie primary runes vs SennaDomination
Electrocute - best Annie rune vs SennaCheap Shot - best Annie rune vs SennaGrisly Mementos - best Annie rune vs SennaRelentless Hunter - best Annie rune vs Senna
Sorcery rune tree - Annie secondary runes vs SennaSorcery
Absolute Focus - best Annie rune vs SennaManaflow Band - best Annie rune vs Senna
50.0% WR

The Domination primary with Sorcery secondary combination helps Annie maximize their potential in this closely contested matchup, providing the right mix of offensive and defensive tools to edge out Senna.


Annie matchup data for League of Legends patch 26.14. The table below shows Annie's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Annie build, runes, laning stats, and early vs late game analysis for that specific matchup.

Annie matchup win rates and stats in League of Legends patch 26.14
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
55.56%815.693311,33651.5%58.3%
47.89%716.091110,69742.1%54.5%
61.02%595.291910,86443.5%72.2%
65.91%445.795911,13850.0%76.9%
59.09%445.479610,91152.9%63.0%
48.84%434.875010,24635.7%55.2%
57.14%425.31,02711,45438.9%70.8%
53.85%395.293011,39964.3%48.0%
48.57%355.99419,48038.9%58.8%
50.00%325.678510,35241.7%55.0%
44.44%275.367210,04930.8%57.1%
44.44%274.992710,28858.3%33.3%
48.00%255.81,07813,85085.7%33.3%
47.83%235.87909,97610.0%76.9%
47.83%235.492110,61950.0%46.7%
60.87%235.286910,80562.5%60.0%
31.82%225.693510,51825.0%35.7%
50.00%224.478510,88716.7%62.5%
38.10%215.171311,68025.0%46.1%
63.16%194.89538,80744.4%80.0%
38.89%185.187610,45622.2%55.6%
47.06%175.482012,29550.0%46.1%
62.50%166.21,09211,21662.5%62.5%
50.00%165.18648,19245.5%60.0%
40.00%155.792811,37916.7%55.6%
33.33%152.67249,93833.3%33.3%
42.86%145.78299,71257.1%28.6%
46.15%135.083711,28060.0%37.5%
69.23%135.189810,97366.7%70.0%
76.92%136.093511,33980.0%75.0%
61.54%135.688410,60175.0%55.6%
41.67%125.08329,73133.3%50.0%
50.00%125.26476,84050.0%50.0%
50.00%125.97469,47150.0%50.0%
72.73%116.31,13513,85866.7%75.0%
54.55%115.568310,77966.7%50.0%
36.36%114.381510,46450.0%28.6%
80.00%106.990410,29966.7%100.0%
50.00%102.86539,28750.0%50.0%
40.00%104.080011,34150.0%33.3%
22.22%95.977511,5310.0%33.3%
11.11%93.57189,5990.0%20.0%
77.78%94.996711,33350.0%85.7%
77.78%92.06419,528100.0%66.7%
62.50%86.092313,01866.7%60.0%
57.14%76.084712,20450.0%60.0%
42.86%71.35858,52075.0%0.0%
28.57%76.41,03212,3910.0%40.0%
71.43%71.47079,557100.0%60.0%
33.33%62.263810,3320.0%50.0%
16.67%65.693713,9620.0%20.0%
16.67%66.27047,41620.0%0.0%
83.33%65.11,0719,25366.7%100.0%
33.33%66.171911,309100.0%20.0%
66.67%66.21,05613,8590.0%66.7%
66.67%62.085012,9120.0%66.7%
20.00%55.785011,3010.0%33.3%
80.00%55.685010,8890.0%100.0%
80.00%56.07649,26866.7%100.0%
60.00%55.372811,47050.0%66.7%
80.00%54.878310,313100.0%50.0%
40.00%53.999612,17250.0%33.3%
40.00%57.01,29011,2560.0%66.7%
80.00%53.88219,389100.0%50.0%

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Annie vs Senna - Frequently Asked Questions

How does Annie do against Senna in League of Legends?

Annie wins the Annie vs Senna matchup with a 50.0% win rate compared to Senna's 50.0%, a 0.0 percentage point difference. This data is based on 10 recent ranked games in patch 26.14.

How does Annie do against Senna in the early game?

In the early game, Annie has the advantage against Senna with a 50.0% win rate versus 50.0%. Annie players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Annie do against Senna in the late game?

In the late game, Annie takes over the Annie vs Senna matchup with a 50.0% win rate compared to 50.0%. Annie scales better into team fights and objective contests after 25 minutes.

Who wins the Annie vs Senna matchup?

Annie wins the matchup against Senna with a 50.0% win rate in League of Legends patch 26.14. The 0.0 percentage point advantage means Annie is slightly favored in this lane matchup based on 10 games analyzed.

What is the best Annie build against Senna?

The best Annie build against Senna includes Liandry's Torment, Malignance, Rylai's Crystal Scepter with Ionian Boots of Lucidity. Check the matchup breakdown above for the full item path and build order.

What are the best Annie runes against Senna?

The best Annie runes against Senna use the Domination primary tree with Sorcery secondary. This rune setup achieves a 50.0% win rate in the Annie vs Senna matchup. See the full rune breakdown in the matchup comparison above.

Does Annie counter Senna?

Yes, Annie has a favorable matchup against Senna with a 50.0% win rate. Annie slightly edges out Senna in lane based on current patch 26.14 data.

How do I play Annie against Senna?

When playing Annie against Senna, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.