Annie - League of Legends Champion
Win Rate
48.6%
Pick Rate
1.8%

Annievs Senna

FMageSupport
Patch26.11
Matches776,441
LaneAll Lanes
TierAll Tiers
Last UpdatedJun 5, 2026
MethodologyData Methodology

Annie vs Senna is a decisive matchup in LoL patch 26.11. Annie wins with a 56.3% win rate (+12.5%) over Senna based on 16 games. Annie holds the advantage in both the early and late game. Below you'll find the best Annie build, runes, laning stats, and strategies for the Annie vs Senna matchup.

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Annie Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Annie performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Annie - 56.3% win rate in this matchup
Annie
56.3% WR
VS
Senna vs Annie matchup - 43.8% win rate
Senna
43.8% WR

Who Wins the Annie vs Senna Matchup?

Annie wins the Annie vs Senna matchup
Winner
Annie
Matches: 16
56.3%
Win Rate
43.8%
2.3
CS / min
2.3
695
DMG / min
650
11,375
Gold / game
11,941
85
Heal / min
379
373
DMG Mitigated / min
349
1.1
CC / min
1.2
66.7%
Early Game WR
33.3%
50.0%
Late Game WR
50.0%

Annie vs Senna Matchup Summary

The Annie vs Senna matchup is a decisive matchup in League of Legends ranked play. Based on 16 recent matches analyzed, Annie wins with a 56.3% win rate compared to Senna's 43.8%, giving Annie a 12.5 percentage point advantage. Annie dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Senna players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Senna leads by 271 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Annie players can confidently pick into Senna and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Senna away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Annie vs Senna Laning Phase Breakdown

Senna wins the laning phase against Annie in League of Legends

Senna is favored during the laning phase against Annie, winning 3 out of 5 key stat categories. Senna holds advantages in gold income, crowd control and sustain, making them the stronger laner in this matchup.

Farming
2.3Annie
2.3Senna
Annie and Senna farm at nearly identical rates in this matchup, with only a 0.0 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
695Annie
650Senna
Annie deals 45 more champion damage per minute than Senna. While noticeable in extended trades, this gap can be offset by Senna choosing favorable fight windows, such as engaging when Annie's key abilities are on cooldown or trading immediately after dodging a skillshot.
Economy
11,375Annie
11,941Senna
Senna earns 566 more gold per game than Annie, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Senna slightly faster item completions.
Utility
1.1Annie
1.2Senna
Both Annie and Senna provide similar amounts of crowd control (0.1s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
458Annie
728Senna
Senna vastly out-sustains Annie, healing and mitigating 271 more damage per minute. This massive durability gap means Senna can absorb significant punishment and remain in lane while Annie is forced to recall. Building grievous wounds early is essential for Annie, and focusing on burst trade patterns rather than sustained fights is critical.

Best Annie Build Against Senna

Sorcerer's Shoes is the optimal boots choice against Senna, providing the mobility and stats Annie needs most in this matchup. The top-performing core items for Annie against Senna are Liandry's Torment, Malignance and Rylai's Crystal Scepter. This combination gives Annie an effective balance of damage, survivability, and utility for the matchup. This build achieves a solid 50.0% win rate across 2 games, proving it to be a reliable item path when facing Senna. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Annie vs Senna matchup.

Early Game vs Late Game

Early Game
Annie
66.7%
+33.3% advantage
Annie early game win rateAnnie66.7%
Senna early game win rateSenna33.3%
Late Game
Annie
50.0%
+0.0% advantage
Annie late game win rateAnnie50.0%
Senna late game win rateSenna50.0%

Annie dominates the early game (first 15 minutes) with a commanding 66.7% win rate — a 33.3 percentage point lead over Senna. This lopsided early game means Annie can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Late game (25+ minutes) is equally balanced, with Annie at 50.0% win rate — only 0.0 points ahead of Senna. Team fight execution and macro play determine the winner at this stage, not champion matchup advantage.

Annie holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Senna players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Annie Runes Against Senna

Domination rune tree - Annie primary runes vs SennaDomination
Electrocute - best Annie rune vs SennaCheap Shot - best Annie rune vs SennaGrisly Mementos - best Annie rune vs SennaRelentless Hunter - best Annie rune vs Senna
Sorcery rune tree - Annie secondary runes vs SennaSorcery
Absolute Focus - best Annie rune vs SennaAxiom Arcanist - best Annie rune vs Senna
100.0% WR

Running Domination primary with Sorcery secondary allows Annie to press their advantage against Senna, amplifying the strengths that make this a favorable matchup.


Annie matchup data for League of Legends patch 26.11. The table below shows Annie's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Annie build, runes, laning stats, and early vs late game analysis for that specific matchup.

Annie matchup win rates and stats in League of Legends patch 26.11
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
46.63%1636.090110,99742.9%49.5%
50.41%1235.891111,27746.8%54.1%
43.56%1015.280511,61038.5%46.8%
47.37%956.098011,15546.1%48.8%
39.78%935.886911,17928.6%49.0%
50.00%745.791511,17850.0%50.0%
49.32%735.387011,07943.8%53.7%
38.03%715.686510,26941.2%35.1%
47.14%705.289011,68541.7%50.0%
42.03%695.881011,31130.8%48.8%
52.31%655.491511,17450.0%53.9%
59.32%595.391711,91052.4%63.2%
51.79%565.298211,64140.0%61.3%
43.40%536.195211,67538.1%46.9%
40.38%525.57329,64136.4%47.4%
35.29%515.885111,57127.8%39.4%
50.00%505.581810,80848.0%52.0%
43.75%485.687210,95839.1%48.0%
40.43%475.89019,13743.8%33.3%
48.94%475.497112,63738.9%55.2%
44.19%435.889011,31140.0%47.8%
48.84%436.177310,57563.6%33.3%
58.14%435.986011,45161.9%54.5%
57.50%406.490911,94346.7%64.0%
53.85%395.994811,07958.8%50.0%
46.15%395.093211,80850.0%43.5%
55.26%385.798913,30662.5%53.3%
56.76%375.990310,95452.6%61.1%
61.11%365.186412,16466.7%59.3%
41.67%365.491310,73025.0%55.0%
51.61%315.884210,31347.4%58.3%
30.00%305.87739,85837.5%21.4%
41.38%295.598410,34037.5%46.1%
42.86%284.886211,81133.3%47.4%
46.43%285.991311,75350.0%44.4%
42.31%264.183911,25741.7%42.9%
53.85%265.89209,34557.1%50.0%
44.00%253.17429,60640.0%46.7%
36.00%254.978910,94241.7%30.8%
63.64%225.779110,67669.2%55.6%
68.18%225.71,08112,12850.0%78.6%
45.45%225.587710,94540.0%50.0%
40.91%225.98829,32520.0%58.3%
36.36%222.377011,96340.0%35.3%
65.00%205.987210,94555.6%72.7%
47.37%195.685411,06425.0%63.6%
42.11%191.67479,54850.0%38.5%
56.25%162.369511,37566.7%50.0%
46.67%154.691310,73550.0%44.4%
60.00%156.21,02812,49960.0%60.0%
28.57%146.39779,4730.0%66.7%
61.54%131.562810,47166.7%57.1%
38.46%136.11,02711,94550.0%33.3%
38.46%135.11,08911,28550.0%28.6%
61.54%131.26969,80675.0%55.6%
63.64%113.56969,58550.0%80.0%
54.55%116.087710,89457.1%50.0%
63.64%111.882510,70550.0%71.4%
54.55%112.17129,97480.0%33.3%
60.00%106.782211,00966.7%50.0%
40.00%101.663811,0390.0%57.1%
60.00%106.598413,174100.0%50.0%
50.00%105.772610,23450.0%50.0%
40.00%104.894812,31933.3%42.9%
60.00%104.91,03613,4940.0%75.0%
66.67%95.794513,13466.7%66.7%
66.67%95.686610,998100.0%50.0%
33.33%95.578211,7800.0%50.0%
66.67%91.85909,98833.3%83.3%
66.67%91.86209,682100.0%57.1%
66.67%96.091410,55666.7%66.7%
25.00%81.57549,4160.0%33.3%
50.00%81.65109,81966.7%40.0%
50.00%85.384611,04150.0%50.0%
28.57%75.81,04913,572100.0%16.7%
57.14%76.280310,91850.0%66.7%
71.43%71.26878,93483.3%0.0%
71.43%75.31,05013,583100.0%60.0%
16.67%65.21,06714,7020.0%16.7%
66.67%61.35269,7190.0%66.7%
66.67%67.01,00412,47966.7%66.7%
16.67%64.576710,99450.0%0.0%
66.67%65.71,07012,75650.0%75.0%
0.00%64.18248,4890.0%0.0%
60.00%56.397310,68250.0%100.0%
40.00%51.56399,29325.0%100.0%
40.00%54.583410,63433.3%50.0%
40.00%51.96089,73050.0%33.3%
80.00%57.01,06210,09675.0%100.0%
20.00%55.87989,6400.0%50.0%
80.00%54.989312,74566.7%100.0%
40.00%51.65858,47133.3%50.0%
60.00%55.291612,2620.0%75.0%

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Annie vs Senna - Frequently Asked Questions

How does Annie do against Senna in League of Legends?

Annie wins the Annie vs Senna matchup with a 56.3% win rate compared to Senna's 43.8%, a 12.5 percentage point difference. This data is based on 16 recent ranked games in patch 26.11.

How does Annie do against Senna in the early game?

In the early game, Annie has the advantage against Senna with a 66.7% win rate versus 33.3%. Annie players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Annie do against Senna in the late game?

In the late game, Annie takes over the Annie vs Senna matchup with a 50.0% win rate compared to 50.0%. Annie scales better into team fights and objective contests after 25 minutes.

Who wins the Annie vs Senna matchup?

Annie wins the matchup against Senna with a 56.3% win rate in League of Legends patch 26.11. The 12.5 percentage point advantage means Annie is significantly favored in this lane matchup based on 16 games analyzed.

What is the best Annie build against Senna?

The best Annie build against Senna includes Liandry's Torment, Malignance, Rylai's Crystal Scepter with Sorcerer's Shoes. This build achieves a 50.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Annie runes against Senna?

The best Annie runes against Senna use the Domination primary tree with Sorcery secondary. This rune setup achieves a 100.0% win rate in the Annie vs Senna matchup. See the full rune breakdown in the matchup comparison above.

Does Annie counter Senna?

Yes, Annie has a favorable matchup against Senna with a 56.3% win rate. Annie strongly counters Senna in lane based on current patch 26.11 data.

How do I play Annie against Senna?

When playing Annie against Senna, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.