
Sennavs Annie
Senna vs Annie is a very close matchup in LoL patch 26.14. Senna wins with a 50.0% win rate (+0.0%) over Annie based on 10 games. Senna holds the advantage in both the early and late game. Below you'll find the best Senna build, runes, laning stats, and strategies for the Senna vs Annie matchup.
Senna Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Senna performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Senna vs Annie Matchup?

Senna vs Annie Matchup Summary
The Senna vs Annie matchup is essentially a coin-flip matchup in League of Legends ranked play. Based on 10 recent matches analyzed, Senna wins with a 50.0% win rate compared to Annie's 50.0%, giving Senna a 0.0 percentage point advantage. Senna holds a slight edge in both the early and late game, but the margins are thin enough that individual skill and jungle attention will often determine the outcome. Annie can still find windows through outplays and team coordination. The most significant statistical gap is in sustain, where Senna leads by 340 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Senna has a statistical edge, but the margin is close enough that respecting Annie's strengths is important. Trade when cooldowns are favorable, track the enemy jungler, and build toward your strongest item spikes to convert the slight advantage into a decisive lead. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Senna vs Annie Laning Phase Breakdown
Senna is favored during the laning phase against Annie, winning 5 out of 5 key stat categories. Senna holds advantages in farming, damage, gold income, crowd control and sustain, making them the stronger laner in this matchup.
Best Senna Build Against Annie
Berserker's Greaves is the optimal boots choice against Annie, providing the mobility and stats Senna needs most in this matchup. The top-performing core items for Senna against Annie are Chempunk Chainsword, Statikk Shiv and Black Cleaver. This combination gives Senna an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Annie. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Senna vs Annie matchup.
Early Game vs Late Game
The early game (first 15 minutes) is a toss-up between Senna and Annie, with Senna holding a razor-thin 50.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.
Late game (25+ minutes) is equally balanced, with Senna at 50.0% win rate — only 0.0 points ahead of Annie. Team fight execution and macro play determine the winner at this stage, not champion matchup advantage.
This matchup is remarkably even at every stage of the game. Neither Senna nor Annie has a phase-specific advantage, making this a pure skill matchup where individual mechanics, decision-making, and team coordination determine the outcome.
Best Senna Runes Against Annie
The Sorcery primary with Inspiration secondary combination helps Senna maximize their potential in this closely contested matchup, providing the right mix of offensive and defensive tools to edge out Annie.
Senna matchup data for League of Legends patch 26.14. The table below shows Senna's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Senna build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 48.48% | 330 | 2.0 | 636 | 10,673 | 50.4% | 47.3% | |
| 46.55% | 232 | 2.0 | 539 | 10,241 | 44.3% | 47.9% | |
| 47.98% | 223 | 5.4 | 732 | 12,244 | 52.4% | 45.3% | |
| 48.83% | 213 | 5.8 | 765 | 12,687 | 43.0% | 52.2% | |
| 45.00% | 180 | 1.7 | 593 | 9,973 | 51.4% | 40.9% | |
| 46.43% | 168 | 1.7 | 597 | 9,666 | 44.0% | 48.4% | |
| 44.24% | 165 | 1.7 | 615 | 10,062 | 46.4% | 42.7% | |
| 48.59% | 142 | 1.9 | 624 | 10,770 | 50.0% | 47.8% | |
| 46.76% | 139 | 5.6 | 768 | 12,540 | 42.9% | 48.9% | |
| 45.26% | 137 | 1.7 | 659 | 10,909 | 42.5% | 46.7% | |
| 49.22% | 128 | 5.1 | 717 | 11,531 | 52.7% | 46.6% | |
| 53.33% | 120 | 1.8 | 623 | 11,315 | 56.1% | 51.9% | |
| 48.15% | 108 | 5.7 | 775 | 11,933 | 44.7% | 50.8% | |
| 50.94% | 106 | 1.6 | 576 | 9,462 | 46.0% | 55.4% | |
| 50.49% | 103 | 2.5 | 711 | 10,553 | 52.4% | 49.2% | |
| 46.60% | 103 | 2.4 | 663 | 10,748 | 37.5% | 52.4% | |
| 54.37% | 103 | 1.6 | 636 | 10,355 | 65.0% | 47.6% | |
| 48.96% | 96 | 3.0 | 663 | 11,126 | 42.1% | 53.5% | |
| 59.34% | 91 | 5.7 | 812 | 12,733 | 52.5% | 64.7% | |
| 53.33% | 90 | 1.8 | 647 | 10,530 | 51.4% | 54.5% | |
| 46.59% | 88 | 6.0 | 713 | 11,620 | 56.8% | 36.4% | |
| 58.33% | 84 | 1.7 | 792 | 11,093 | 65.5% | 54.5% | |
| 50.60% | 83 | 1.6 | 586 | 9,475 | 56.8% | 43.6% | |
| 46.91% | 81 | 5.8 | 851 | 12,527 | 32.4% | 57.5% | |
| 42.86% | 77 | 2.0 | 620 | 10,004 | 48.4% | 39.1% | |
| 38.96% | 77 | 1.8 | 589 | 10,389 | 52.0% | 32.7% | |
| 52.05% | 73 | 5.6 | 729 | 12,088 | 48.3% | 54.5% | |
| 61.97% | 71 | 1.8 | 663 | 10,244 | 66.7% | 58.5% | |
| 48.53% | 68 | 1.8 | 654 | 10,595 | 66.7% | 36.6% | |
| 54.41% | 68 | 1.7 | 670 | 10,739 | 54.2% | 54.5% | |
| 59.70% | 67 | 5.9 | 869 | 14,142 | 61.1% | 59.2% | |
| 50.75% | 67 | 1.6 | 724 | 10,484 | 54.5% | 48.9% | |
| 52.31% | 65 | 5.6 | 809 | 11,962 | 56.5% | 50.0% | |
| 60.94% | 64 | 5.9 | 849 | 12,098 | 61.3% | 60.6% | |
| 38.10% | 63 | 1.6 | 706 | 10,377 | 34.8% | 40.0% | |
| 31.58% | 57 | 2.1 | 577 | 10,199 | 28.0% | 34.4% | |
| 49.12% | 57 | 5.8 | 820 | 12,088 | 45.2% | 53.9% | |
| 54.39% | 57 | 1.8 | 656 | 10,089 | 46.7% | 63.0% | |
| 60.00% | 55 | 1.6 | 532 | 9,133 | 66.7% | 52.0% | |
| 35.19% | 54 | 5.5 | 803 | 11,809 | 43.5% | 29.0% | |
| 52.94% | 51 | 1.6 | 692 | 9,696 | 65.2% | 42.9% | |
| 46.00% | 50 | 2.8 | 619 | 11,600 | 38.5% | 48.6% | |
| 40.82% | 49 | 1.8 | 718 | 10,555 | 40.9% | 40.7% | |
| 51.22% | 41 | 1.5 | 568 | 10,175 | 38.5% | 57.1% | |
| 48.72% | 39 | 4.7 | 733 | 13,296 | 45.5% | 50.0% | |
| 58.97% | 39 | 4.1 | 628 | 11,118 | 52.9% | 63.6% | |
| 58.97% | 39 | 1.7 | 732 | 9,913 | 63.2% | 55.0% | |
| 57.89% | 38 | 5.9 | 816 | 13,620 | 50.0% | 61.5% | |
| 60.61% | 33 | 6.1 | 833 | 12,992 | 50.0% | 70.6% | |
| 43.75% | 32 | 1.7 | 617 | 10,184 | 30.8% | 52.6% | |
| 48.39% | 31 | 2.1 | 655 | 11,292 | 55.6% | 45.5% | |
| 26.67% | 30 | 1.8 | 595 | 8,586 | 40.0% | 13.3% | |
| 62.96% | 27 | 5.8 | 893 | 12,795 | 58.3% | 66.7% | |
| 62.96% | 27 | 5.8 | 666 | 12,062 | 54.5% | 68.8% | |
| 61.54% | 26 | 1.5 | 593 | 9,462 | 61.5% | 61.5% | |
| 50.00% | 24 | 6.2 | 805 | 14,306 | 62.5% | 43.8% | |
| 45.83% | 24 | 1.8 | 627 | 10,632 | 40.0% | 50.0% | |
| 40.00% | 20 | 2.1 | 635 | 9,591 | 30.8% | 57.1% | |
| 60.00% | 20 | 5.8 | 850 | 11,309 | 58.3% | 62.5% | |
| 61.11% | 18 | 1.4 | 699 | 9,364 | 72.7% | 42.9% | |
| 55.56% | 18 | 3.0 | 794 | 11,197 | 77.8% | 33.3% | |
| 38.89% | 18 | 5.7 | 653 | 11,752 | 33.3% | 44.4% | |
| 61.11% | 18 | 3.4 | 722 | 10,546 | 50.0% | 66.7% | |
| 44.44% | 18 | 5.9 | 800 | 12,256 | 44.4% | 44.4% | |
| 52.94% | 17 | 1.4 | 680 | 11,556 | 66.7% | 45.5% | |
| 47.06% | 17 | 5.9 | 901 | 13,681 | 25.0% | 53.9% | |
| 47.06% | 17 | 1.9 | 609 | 10,388 | 12.5% | 77.8% | |
| 66.67% | 15 | 2.0 | 715 | 10,828 | 83.3% | 55.6% | |
| 57.14% | 14 | 6.2 | 858 | 14,168 | 33.3% | 63.6% | |
| 46.15% | 13 | 5.7 | 775 | 12,417 | 40.0% | 50.0% | |
| 58.33% | 12 | 2.7 | 924 | 12,526 | 40.0% | 71.4% | |
| 63.64% | 11 | 2.0 | 514 | 11,508 | 75.0% | 57.1% | |
| 63.64% | 11 | 2.2 | 665 | 10,183 | 40.0% | 83.3% | |
| 40.00% | 10 | 5.9 | 642 | 10,259 | 66.7% | 0.0% | |
| 40.00% | 10 | 3.0 | 653 | 11,817 | 20.0% | 60.0% | |
| 60.00% | 10 | 3.6 | 690 | 11,690 | 100.0% | 42.9% | |
| 50.00% | 10 | 1.5 | 567 | 11,633 | 0.0% | 55.6% | |
| 50.00% | 10 | 3.5 | 864 | 11,193 | 50.0% | 50.0% | |
| 70.00% | 10 | 5.6 | 631 | 9,672 | 60.0% | 80.0% | |
| 37.50% | 8 | 6.3 | 847 | 12,445 | 25.0% | 50.0% | |
| 12.50% | 8 | 1.8 | 512 | 7,212 | 0.0% | 25.0% | |
| 37.50% | 8 | 2.7 | 752 | 9,803 | 0.0% | 75.0% | |
| 42.86% | 7 | 2.8 | 721 | 11,554 | 0.0% | 60.0% | |
| 57.14% | 7 | 5.2 | 862 | 12,973 | 33.3% | 75.0% | |
| 71.43% | 7 | 3.8 | 759 | 14,755 | 100.0% | 66.7% | |
| 57.14% | 7 | 2.3 | 1,051 | 10,414 | 33.3% | 75.0% | |
| 42.86% | 7 | 4.8 | 781 | 9,224 | 0.0% | 75.0% | |
| 50.00% | 6 | 5.8 | 682 | 7,090 | 40.0% | 100.0% | |
| 50.00% | 6 | 2.8 | 604 | 12,379 | 0.0% | 50.0% | |
| 66.67% | 6 | 2.5 | 816 | 13,453 | 100.0% | 60.0% | |
| 20.00% | 5 | 4.0 | 674 | 10,639 | 33.3% | 0.0% | |
| 40.00% | 5 | 3.9 | 851 | 10,720 | 33.3% | 50.0% | |
| 20.00% | 5 | 4.8 | 744 | 11,731 | 0.0% | 25.0% | |
| 60.00% | 5 | 4.5 | 657 | 8,057 | 50.0% | 100.0% | |
| 80.00% | 5 | 5.5 | 768 | 11,618 | 100.0% | 75.0% | |
| 60.00% | 5 | 6.5 | 724 | 9,877 | 33.3% | 100.0% | |
| 60.00% | 5 | 5.5 | 719 | 11,350 | 100.0% | 50.0% | |
| 40.00% | 5 | 3.9 | 665 | 9,641 | 66.7% | 0.0% | |
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Senna vs Annie - Frequently Asked Questions
How does Senna do against Annie in League of Legends?
Senna wins the Senna vs Annie matchup with a 50.0% win rate compared to Annie's 50.0%, a 0.0 percentage point difference. This data is based on 10 recent ranked games in patch 26.14.
How does Senna do against Annie in the early game?
In the early game, Senna has the advantage against Annie with a 50.0% win rate versus 50.0%. Senna players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Senna do against Annie in the late game?
In the late game, Senna takes over the Senna vs Annie matchup with a 50.0% win rate compared to 50.0%. Senna scales better into team fights and objective contests after 25 minutes.
Who wins the Senna vs Annie matchup?
Senna wins the matchup against Annie with a 50.0% win rate in League of Legends patch 26.14. The 0.0 percentage point advantage means Senna is slightly favored in this lane matchup based on 10 games analyzed.
What is the best Senna build against Annie?
The best Senna build against Annie includes Chempunk Chainsword, Statikk Shiv, Black Cleaver with Berserker's Greaves. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.
What are the best Senna runes against Annie?
The best Senna runes against Annie use the Sorcery primary tree with Inspiration secondary. This rune setup achieves a 100.0% win rate in the Senna vs Annie matchup. See the full rune breakdown in the matchup comparison above.
Does Senna counter Annie?
Yes, Senna has a favorable matchup against Annie with a 50.0% win rate. Senna slightly edges out Annie in lane based on current patch 26.14 data.
How do I play Senna against Annie?
When playing Senna against Annie, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.
