Caitlyn - League of Legends Champion
Win Rate
49.6%
Pick Rate
9.8%

Caitlynvs Seraphine

CMarksman
Patch26.5
Matches469,660
LaneAll Lanes
TierAll Tiers
Last UpdatedMar 16, 2026
MethodologyData Methodology

Caitlyn vs Seraphine is a decisive matchup in LoL patch 26.5. Seraphine wins with a 57.9% win rate (+15.8%) over Caitlyn based on 38 games. Caitlyn wins the early laning phase while Seraphine scales better into the late game. Below you'll find the best Caitlyn build, runes, laning stats, and strategies for the Caitlyn vs Seraphine matchup.

Caitlyn Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Caitlyn performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Seraphine - 42.1% win rateSeraphine(42.1%)
Caitlyn - 42.1% win rate in this matchup
Caitlyn
42.1% WR
VS
Seraphine vs Caitlyn matchup - 57.9% win rate
Seraphine
57.9% WR

Who Wins the Caitlyn vs Seraphine Matchup?

Seraphine wins the Caitlyn vs Seraphine matchup
Winner
Seraphine
Matches: 38
42.1%
Win Rate
57.9%
6.6
CS / min
6.1
670
DMG / min
774
12,691
Gold / game
12,590
166
Heal / min
267
337
DMG Mitigated / min
397
0.6
CC / min
1.3
50.0%
Early Game WR
50.0%
37.5%
Late Game WR
62.5%

Caitlyn vs Seraphine Matchup Summary

The Caitlyn vs Seraphine matchup is a decisive matchup in League of Legends ranked play. Based on 38 recent matches analyzed, Seraphine wins with a 57.9% win rate compared to Caitlyn's 42.1%, giving Seraphine a 15.8 percentage point advantage. Game phase dynamics play a critical role here: Caitlyn controls the early laning stage, but Seraphine outscales as the game goes longer. The matchup shifts dramatically depending on game length — Caitlyn needs to press advantages before Seraphine reaches their power spikes, while Seraphine should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Seraphine leads by 0.7s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Seraphine has a strong advantage in this matchup. Caitlyn players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Seraphine overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Caitlyn vs Seraphine Laning Phase Breakdown

Seraphine wins the laning phase against Caitlyn in League of Legends

Seraphine is favored during the laning phase against Caitlyn, winning 3 out of 5 key stat categories. Seraphine holds advantages in damage, crowd control and sustain, making them the stronger laner in this matchup.

Farming
6.6Caitlyn
6.1Seraphine
Caitlyn edges out Seraphine by 0.5 CS per minute — a moderate farming advantage that adds up to roughly 8 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Caitlyn.
Damage
670Caitlyn
774Seraphine
Seraphine heavily out-damages Caitlyn by 104 DMG/min, dominating both short trades and all-in fights. Caitlyn should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Seraphine's sustained damage advantage take over.
Economy
12,691Caitlyn
12,590Seraphine
Caitlyn and Seraphine generate nearly equal gold per game, with just a 101 gold difference. Neither champion has a clear economic advantage, so gold leads will depend on individual play quality, kill participation, and objective contributions.
Utility
0.6Caitlyn
1.3Seraphine
Seraphine provides 0.7 seconds more crowd control per minute than Caitlyn, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Seraphine coordinate with their jungler and control the pace of skirmishes.
Sustain
503Caitlyn
664Seraphine
Seraphine vastly out-sustains Caitlyn, healing and mitigating 161 more damage per minute. This massive durability gap means Seraphine can absorb significant punishment and remain in lane while Caitlyn is forced to recall. Building grievous wounds early is essential for Caitlyn, and focusing on burst trade patterns rather than sustained fights is critical.

Early Game vs Late Game

Early Game
Caitlyn
50.0%
+0.0% advantage
Caitlyn early game win rateCaitlyn50.0%
Seraphine early game win rateSeraphine50.0%
Late Game
Seraphine
62.5%
+25.0% advantage
Caitlyn late game win rateCaitlyn37.5%
Seraphine late game win rateSeraphine62.5%

The early game (first 15 minutes) is a toss-up between Caitlyn and Seraphine, with Caitlyn holding a razor-thin 50.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.

Seraphine is far superior in the late game (25+ minutes), boasting a 62.5% win rate — 25.0 points above Caitlyn. Extended games heavily favor Seraphine, whose kit and scaling make them a dominant force in team fights and objective control.

The power dynamics shift as the game progresses — Caitlyn has the edge early, but Seraphine gradually takes over. However, the margins are slim enough that either champion can win at any stage with the right plays. Focus on taking advantages when you have them rather than waiting for a specific game phase.

Best Caitlyn Runes Against Seraphine

Precision rune tree - Caitlyn primary runes vs SeraphinePrecision
Lethal Tempo - best Caitlyn rune vs SeraphineAbsorb Life - best Caitlyn rune vs SeraphineLegend: Bloodline - best Caitlyn rune vs SeraphineCoup de Grace - best Caitlyn rune vs Seraphine
Sorcery rune tree - Caitlyn secondary runes vs SeraphineSorcery
Absolute Focus - best Caitlyn rune vs SeraphineGathering Storm - best Caitlyn rune vs Seraphine
100.0% WR

The Precision and Sorcery rune setup gives Caitlyn the best tools to compete against Seraphine in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Caitlyn matchup data for League of Legends patch 26.5. The table below shows Caitlyn's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Caitlyn build, runes, laning stats, and early vs late game analysis for that specific matchup.

Caitlyn matchup win rates and stats in League of Legends patch 26.5
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
47.83%9686.684413,56347.0%48.5%
45.94%8496.990913,81843.6%48.0%
49.23%8406.986413,83053.6%46.1%
45.75%6126.883813,41545.5%46.0%
50.54%5607.088313,73748.0%52.6%
47.84%4857.089913,91349.3%46.8%
51.37%4387.091114,32053.8%49.6%
54.81%3436.896414,44157.1%52.9%
50.16%3176.779813,48161.3%41.1%
46.81%2826.688413,65648.8%45.3%
50.00%2707.186713,70652.6%47.4%
52.19%2516.689213,84254.8%50.0%
53.66%2466.990313,69957.1%50.4%
49.17%2407.089413,90656.1%41.9%
55.17%2327.086414,13756.0%54.6%
54.95%2027.098114,73060.5%51.2%
50.79%1906.686513,15850.0%51.8%
49.18%1836.883113,57243.8%52.7%
48.28%1166.885413,42349.0%47.8%
47.37%1146.597613,68336.6%53.4%
49.56%1137.289414,21948.0%50.8%
54.46%1126.997213,88458.2%50.9%
52.68%1126.777113,25746.0%58.1%
33.96%1066.883213,27223.3%41.3%
49.50%1016.884913,98043.2%53.1%
52.69%936.787314,64056.8%50.0%
44.94%897.21,00113,96147.5%42.9%
58.44%776.81,02915,17356.7%59.6%
64.00%756.91,00415,14276.3%51.4%
55.00%406.680314,61453.3%56.0%
51.28%396.885814,49855.6%47.6%
42.11%386.667012,69150.0%37.5%
55.26%387.292415,11346.1%60.0%
30.00%306.586813,78933.3%26.7%
60.71%286.786015,07333.3%73.7%
55.00%206.272713,06755.6%54.5%
61.11%186.086615,86150.0%70.0%
47.06%177.288414,35950.0%45.5%
42.86%147.186011,58344.4%40.0%
57.14%146.895814,53057.1%57.1%
35.71%146.51,08614,34957.1%14.3%
50.00%126.81,07815,33950.0%50.0%
60.00%106.983614,64140.0%80.0%
55.56%96.483815,529100.0%42.9%
44.44%96.588414,9100.0%57.1%
66.67%97.41,28914,40680.0%50.0%
44.44%96.569815,06366.7%33.3%
44.44%95.879711,830100.0%16.7%
55.56%96.377712,07250.0%60.0%
55.56%97.01,11515,24050.0%60.0%
50.00%87.578312,52866.7%40.0%
25.00%87.485211,26225.0%25.0%
50.00%87.71,21514,37266.7%40.0%
50.00%86.91,19213,51160.0%33.3%
75.00%86.581515,2930.0%85.7%
42.86%76.682214,9140.0%50.0%
16.67%66.99448,71820.0%0.0%
16.67%66.581714,1550.0%33.3%
0.00%66.777910,9270.0%0.0%
100.00%55.979911,313100.0%100.0%
40.00%56.285416,1660.0%40.0%
60.00%56.71,13912,50233.3%100.0%
20.00%56.875214,23850.0%0.0%
80.00%57.31,00312,345100.0%50.0%
60.00%56.765313,925100.0%33.3%

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Caitlyn vs Seraphine - Frequently Asked Questions

How does Caitlyn do against Seraphine in League of Legends?

Seraphine wins the Caitlyn vs Seraphine matchup with a 57.9% win rate compared to Caitlyn's 42.1%, a 15.8 percentage point difference. This data is based on 38 recent ranked games in patch 26.5.

How does Caitlyn do against Seraphine in the early game?

In the early game, Caitlyn has the advantage against Seraphine with a 50.0% win rate versus 50.0%. Caitlyn players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Caitlyn do against Seraphine in the late game?

In the late game, Seraphine takes over the Caitlyn vs Seraphine matchup with a 62.5% win rate compared to 37.5%. Seraphine scales better into team fights and objective contests after 25 minutes.

Who wins the Caitlyn vs Seraphine matchup?

Seraphine wins the matchup against Caitlyn with a 57.9% win rate in League of Legends patch 26.5. The 15.8 percentage point advantage means Seraphine is significantly favored in this lane matchup based on 38 games analyzed.

What is the best Caitlyn build against Seraphine?

The best Caitlyn build against Seraphine includes optimized core items. Check the matchup breakdown above for the full item path and build order.

What are the best Caitlyn runes against Seraphine?

The best Caitlyn runes against Seraphine use the Precision primary tree with Sorcery secondary. This rune setup achieves a 100.0% win rate in the Caitlyn vs Seraphine matchup. See the full rune breakdown in the matchup comparison above.

Does Caitlyn counter Seraphine?

No, Caitlyn struggles against Seraphine with only a 42.1% win rate. Seraphine has the advantage in this matchup. Caitlyn players should focus on safe farming and avoiding extended trades to minimize Seraphine's lead.

How do I play Caitlyn against Seraphine?

When playing Caitlyn against Seraphine, play cautiously and avoid Seraphine's power spikes. Look for jungle assistance and team-dependent plays since Seraphine has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.