Caitlyn - League of Legends Champion
Win Rate
48.4%
Pick Rate
9.5%

Caitlynvs Seraphine

DMarksman
Patch26.12
Matches157,752
LaneAll Lanes
TierAll Tiers
Last UpdatedJun 17, 2026
MethodologyData Methodology

Caitlyn vs Seraphine is a decisive matchup in LoL patch 26.12. Caitlyn wins with a 54.5% win rate (+9.1%) over Seraphine based on 22 games. Seraphine wins the early laning phase while Caitlyn scales better into the late game. Below you'll find the best Caitlyn build, runes, laning stats, and strategies for the Caitlyn vs Seraphine matchup.

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Caitlyn Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Caitlyn performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Caitlyn - 54.5% win rate in this matchup
Caitlyn
54.5% WR
VS
Seraphine vs Caitlyn matchup - 45.5% win rate
Seraphine
45.5% WR

Who Wins the Caitlyn vs Seraphine Matchup?

Caitlyn wins the Caitlyn vs Seraphine matchup
Winner
Caitlyn
Matches: 22
54.5%
Win Rate
45.5%
6.8
CS / min
5.9
778
DMG / min
878
12,603
Gold / game
11,755
154
Heal / min
137
393
DMG Mitigated / min
471
0.6
CC / min
1.6
44.4%
Early Game WR
55.6%
61.5%
Late Game WR
38.5%

Caitlyn vs Seraphine Matchup Summary

The Caitlyn vs Seraphine matchup is a decisive matchup in League of Legends ranked play. Based on 22 recent matches analyzed, Caitlyn wins with a 54.5% win rate compared to Seraphine's 45.5%, giving Caitlyn a 9.1 percentage point advantage. Game phase dynamics play a critical role here: Seraphine controls the early laning stage, but Caitlyn outscales as the game goes longer. The matchup shifts dramatically depending on game length — Seraphine needs to press advantages before Caitlyn reaches their power spikes, while Caitlyn should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Seraphine leads by 1.0s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Caitlyn players can confidently pick into Seraphine and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Seraphine away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Caitlyn vs Seraphine Laning Phase Breakdown

Seraphine wins the laning phase against Caitlyn in League of Legends

Seraphine is favored during the laning phase against Caitlyn, winning 3 out of 5 key stat categories. Seraphine holds advantages in damage, crowd control and sustain, making them the stronger laner in this matchup.

Farming
6.8Caitlyn
5.9Seraphine
Caitlyn significantly out-farms Seraphine by 1.0 CS per minute, accumulating an estimated 15 CS lead by mid game. This substantial farming gap gives Caitlyn a major gold advantage and earlier item completions. Seraphine players should prioritize wave management techniques like freezing near tower and using abilities efficiently to minimize the deficit.
Damage
778Caitlyn
878Seraphine
Seraphine heavily out-damages Caitlyn by 101 DMG/min, dominating both short trades and all-in fights. Caitlyn should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Seraphine's sustained damage advantage take over.
Economy
12,603Caitlyn
11,755Seraphine
Caitlyn generates a commanding 849 more gold per game than Seraphine. This substantial economic advantage means Caitlyn consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Seraphine should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.6Caitlyn
1.6Seraphine
Seraphine brings significantly more crowd control than Caitlyn, with 1.0 more seconds of CC per minute. This large utility gap makes Seraphine far more valuable in setting up jungle ganks, controlling objectives, and locking down targets in team fights. Caitlyn should invest in tenacity and position carefully to avoid being chain-CC'd.
Sustain
547Caitlyn
608Seraphine
Seraphine heals and mitigates 61 more damage per minute than Caitlyn, providing moderate extra durability. This sustain edge allows Seraphine to stay in lane longer between recalls and gradually win extended wars of attrition. Consider building early grievous wounds if playing Caitlyn.

Early Game vs Late Game

Early Game
Seraphine
55.6%
+11.1% advantage
Caitlyn early game win rateCaitlyn44.4%
Seraphine early game win rateSeraphine55.6%
Late Game
Caitlyn
61.5%
+23.1% advantage
Caitlyn late game win rateCaitlyn61.5%
Seraphine late game win rateSeraphine38.5%

Seraphine dominates the early game (first 15 minutes) with a commanding 55.6% win rate — a 11.1 percentage point lead over Caitlyn. This lopsided early game means Seraphine can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Caitlyn is far superior in the late game (25+ minutes), boasting a 61.5% win rate — 23.1 points above Seraphine. Extended games heavily favor Caitlyn, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Seraphine must aggressively press their early advantage and close out the game before Caitlyn reaches their scaling breakpoints. If Caitlyn survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Caitlyn Runes Against Seraphine

Precision rune tree - Caitlyn primary runes vs SeraphinePrecision
Lethal Tempo - best Caitlyn rune vs SeraphinePresence of Mind - best Caitlyn rune vs SeraphineLegend: Bloodline - best Caitlyn rune vs SeraphineCut Down - best Caitlyn rune vs Seraphine
Inspiration rune tree - Caitlyn secondary runes vs SeraphineInspiration
Cash Back - best Caitlyn rune vs SeraphineCosmic Insight - best Caitlyn rune vs Seraphine
100.0% WR

Running Precision primary with Inspiration secondary allows Caitlyn to press their advantage against Seraphine, amplifying the strengths that make this a favorable matchup.


Caitlyn matchup data for League of Legends patch 26.12. The table below shows Caitlyn's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Caitlyn build, runes, laning stats, and early vs late game analysis for that specific matchup.

Caitlyn matchup win rates and stats in League of Legends patch 26.12
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
49.19%2466.783912,97546.1%51.9%
47.70%2396.891313,57452.9%43.8%
46.03%2396.882812,81844.2%47.4%
55.02%2296.891513,37858.3%51.4%
43.12%2196.780613,05541.8%44.2%
51.90%1586.986613,31849.2%53.8%
45.61%1146.992414,48955.6%41.0%
48.62%1096.991514,25641.7%52.0%
55.66%1066.895513,94256.8%54.8%
50.52%977.093213,89058.3%45.9%
56.82%886.681914,02660.0%54.7%
56.76%746.889313,13057.9%55.6%
40.54%747.377612,96334.3%46.1%
47.14%706.782113,20050.0%44.1%
45.00%606.688613,13839.3%50.0%
35.59%596.880712,95836.0%35.3%
59.65%577.283212,68264.0%56.3%
50.00%546.772712,33852.0%48.3%
55.77%526.890012,37259.3%52.0%
46.81%476.786412,71765.0%33.3%
55.81%437.181812,88272.0%33.3%
43.90%416.869112,89746.1%42.9%
29.03%316.683614,00330.0%28.6%
37.50%246.888112,83138.5%36.4%
54.55%226.877812,60344.4%61.5%
52.38%216.977613,31860.0%50.0%
42.86%217.083411,49554.5%30.0%
45.00%206.464111,14033.3%54.5%
45.00%206.882013,31850.0%40.0%
42.11%196.882312,48544.4%40.0%
50.00%187.177412,81575.0%30.0%
57.14%146.71,07912,01650.0%66.7%
50.00%147.081213,99842.9%57.1%
35.71%145.968910,32042.9%28.6%
41.67%125.81,10313,3380.0%55.6%
27.27%117.280614,30460.0%0.0%
50.00%107.085015,00850.0%50.0%
50.00%107.11,25111,97375.0%33.3%
42.86%77.676212,69766.7%25.0%
33.33%65.376312,6100.0%66.7%
16.67%66.875713,6090.0%25.0%
16.67%67.77409,9050.0%50.0%
66.67%66.383511,61466.7%66.7%
50.00%65.574814,9280.0%60.0%
60.00%57.795310,457100.0%33.3%

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Caitlyn vs Seraphine - Frequently Asked Questions

How does Caitlyn do against Seraphine in League of Legends?

Caitlyn wins the Caitlyn vs Seraphine matchup with a 54.5% win rate compared to Seraphine's 45.5%, a 9.1 percentage point difference. This data is based on 22 recent ranked games in patch 26.12.

How does Caitlyn do against Seraphine in the early game?

In the early game, Seraphine has the advantage against Caitlyn with a 55.6% win rate versus 44.4%. Seraphine players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Caitlyn do against Seraphine in the late game?

In the late game, Caitlyn takes over the Caitlyn vs Seraphine matchup with a 61.5% win rate compared to 38.5%. Caitlyn scales better into team fights and objective contests after 25 minutes.

Who wins the Caitlyn vs Seraphine matchup?

Caitlyn wins the matchup against Seraphine with a 54.5% win rate in League of Legends patch 26.12. The 9.1 percentage point advantage means Caitlyn is significantly favored in this lane matchup based on 22 games analyzed.

What is the best Caitlyn build against Seraphine?

The best Caitlyn build against Seraphine includes optimized core items. Check the matchup breakdown above for the full item path and build order.

What are the best Caitlyn runes against Seraphine?

The best Caitlyn runes against Seraphine use the Precision primary tree with Inspiration secondary. This rune setup achieves a 100.0% win rate in the Caitlyn vs Seraphine matchup. See the full rune breakdown in the matchup comparison above.

Does Caitlyn counter Seraphine?

Yes, Caitlyn has a favorable matchup against Seraphine with a 54.5% win rate. Caitlyn strongly counters Seraphine in lane based on current patch 26.12 data.

How do I play Caitlyn against Seraphine?

When playing Caitlyn against Seraphine, leverage your statistical advantages by trading aggressively during favorable windows. Play safe early and scale into your power spikes where you outperform Seraphine. Build the recommended items and runes for this specific matchup for the best results.