
Caitlynvs Seraphine
Caitlyn vs Seraphine is a decisive matchup in LoL patch 26.5. Seraphine wins with a 57.9% win rate (+15.8%) over Caitlyn based on 38 games. Caitlyn wins the early laning phase while Seraphine scales better into the late game. Below you'll find the best Caitlyn build, runes, laning stats, and strategies for the Caitlyn vs Seraphine matchup.
Caitlyn Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Caitlyn performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Caitlyn vs Seraphine Matchup?

Caitlyn vs Seraphine Matchup Summary
The Caitlyn vs Seraphine matchup is a decisive matchup in League of Legends ranked play. Based on 38 recent matches analyzed, Seraphine wins with a 57.9% win rate compared to Caitlyn's 42.1%, giving Seraphine a 15.8 percentage point advantage. Game phase dynamics play a critical role here: Caitlyn controls the early laning stage, but Seraphine outscales as the game goes longer. The matchup shifts dramatically depending on game length — Caitlyn needs to press advantages before Seraphine reaches their power spikes, while Seraphine should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Seraphine leads by 0.7s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Seraphine has a strong advantage in this matchup. Caitlyn players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Seraphine overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Caitlyn vs Seraphine Laning Phase Breakdown
Seraphine is favored during the laning phase against Caitlyn, winning 3 out of 5 key stat categories. Seraphine holds advantages in damage, crowd control and sustain, making them the stronger laner in this matchup.
Early Game vs Late Game
The early game (first 15 minutes) is a toss-up between Caitlyn and Seraphine, with Caitlyn holding a razor-thin 50.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.
Seraphine is far superior in the late game (25+ minutes), boasting a 62.5% win rate — 25.0 points above Caitlyn. Extended games heavily favor Seraphine, whose kit and scaling make them a dominant force in team fights and objective control.
The power dynamics shift as the game progresses — Caitlyn has the edge early, but Seraphine gradually takes over. However, the margins are slim enough that either champion can win at any stage with the right plays. Focus on taking advantages when you have them rather than waiting for a specific game phase.
Best Caitlyn Runes Against Seraphine
The Precision and Sorcery rune setup gives Caitlyn the best tools to compete against Seraphine in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.
Caitlyn matchup data for League of Legends patch 26.5. The table below shows Caitlyn's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Caitlyn build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 47.83% | 968 | 6.6 | 844 | 13,563 | 47.0% | 48.5% | |
| 45.94% | 849 | 6.9 | 909 | 13,818 | 43.6% | 48.0% | |
| 49.23% | 840 | 6.9 | 864 | 13,830 | 53.6% | 46.1% | |
| 45.75% | 612 | 6.8 | 838 | 13,415 | 45.5% | 46.0% | |
| 50.54% | 560 | 7.0 | 883 | 13,737 | 48.0% | 52.6% | |
| 47.84% | 485 | 7.0 | 899 | 13,913 | 49.3% | 46.8% | |
| 51.37% | 438 | 7.0 | 911 | 14,320 | 53.8% | 49.6% | |
| 54.81% | 343 | 6.8 | 964 | 14,441 | 57.1% | 52.9% | |
| 50.16% | 317 | 6.7 | 798 | 13,481 | 61.3% | 41.1% | |
| 46.81% | 282 | 6.6 | 884 | 13,656 | 48.8% | 45.3% | |
| 50.00% | 270 | 7.1 | 867 | 13,706 | 52.6% | 47.4% | |
| 52.19% | 251 | 6.6 | 892 | 13,842 | 54.8% | 50.0% | |
| 53.66% | 246 | 6.9 | 903 | 13,699 | 57.1% | 50.4% | |
| 49.17% | 240 | 7.0 | 894 | 13,906 | 56.1% | 41.9% | |
| 55.17% | 232 | 7.0 | 864 | 14,137 | 56.0% | 54.6% | |
| 54.95% | 202 | 7.0 | 981 | 14,730 | 60.5% | 51.2% | |
| 50.79% | 190 | 6.6 | 865 | 13,158 | 50.0% | 51.8% | |
| 49.18% | 183 | 6.8 | 831 | 13,572 | 43.8% | 52.7% | |
| 48.28% | 116 | 6.8 | 854 | 13,423 | 49.0% | 47.8% | |
| 47.37% | 114 | 6.5 | 976 | 13,683 | 36.6% | 53.4% | |
| 49.56% | 113 | 7.2 | 894 | 14,219 | 48.0% | 50.8% | |
| 54.46% | 112 | 6.9 | 972 | 13,884 | 58.2% | 50.9% | |
| 52.68% | 112 | 6.7 | 771 | 13,257 | 46.0% | 58.1% | |
| 33.96% | 106 | 6.8 | 832 | 13,272 | 23.3% | 41.3% | |
| 49.50% | 101 | 6.8 | 849 | 13,980 | 43.2% | 53.1% | |
| 52.69% | 93 | 6.7 | 873 | 14,640 | 56.8% | 50.0% | |
| 44.94% | 89 | 7.2 | 1,001 | 13,961 | 47.5% | 42.9% | |
| 58.44% | 77 | 6.8 | 1,029 | 15,173 | 56.7% | 59.6% | |
| 64.00% | 75 | 6.9 | 1,004 | 15,142 | 76.3% | 51.4% | |
| 55.00% | 40 | 6.6 | 803 | 14,614 | 53.3% | 56.0% | |
| 51.28% | 39 | 6.8 | 858 | 14,498 | 55.6% | 47.6% | |
| 42.11% | 38 | 6.6 | 670 | 12,691 | 50.0% | 37.5% | |
| 55.26% | 38 | 7.2 | 924 | 15,113 | 46.1% | 60.0% | |
| 30.00% | 30 | 6.5 | 868 | 13,789 | 33.3% | 26.7% | |
| 60.71% | 28 | 6.7 | 860 | 15,073 | 33.3% | 73.7% | |
| 55.00% | 20 | 6.2 | 727 | 13,067 | 55.6% | 54.5% | |
| 61.11% | 18 | 6.0 | 866 | 15,861 | 50.0% | 70.0% | |
| 47.06% | 17 | 7.2 | 884 | 14,359 | 50.0% | 45.5% | |
| 42.86% | 14 | 7.1 | 860 | 11,583 | 44.4% | 40.0% | |
| 57.14% | 14 | 6.8 | 958 | 14,530 | 57.1% | 57.1% | |
| 35.71% | 14 | 6.5 | 1,086 | 14,349 | 57.1% | 14.3% | |
| 50.00% | 12 | 6.8 | 1,078 | 15,339 | 50.0% | 50.0% | |
| 60.00% | 10 | 6.9 | 836 | 14,641 | 40.0% | 80.0% | |
| 55.56% | 9 | 6.4 | 838 | 15,529 | 100.0% | 42.9% | |
| 44.44% | 9 | 6.5 | 884 | 14,910 | 0.0% | 57.1% | |
| 66.67% | 9 | 7.4 | 1,289 | 14,406 | 80.0% | 50.0% | |
| 44.44% | 9 | 6.5 | 698 | 15,063 | 66.7% | 33.3% | |
| 44.44% | 9 | 5.8 | 797 | 11,830 | 100.0% | 16.7% | |
| 55.56% | 9 | 6.3 | 777 | 12,072 | 50.0% | 60.0% | |
| 55.56% | 9 | 7.0 | 1,115 | 15,240 | 50.0% | 60.0% | |
| 50.00% | 8 | 7.5 | 783 | 12,528 | 66.7% | 40.0% | |
| 25.00% | 8 | 7.4 | 852 | 11,262 | 25.0% | 25.0% | |
| 50.00% | 8 | 7.7 | 1,215 | 14,372 | 66.7% | 40.0% | |
| 50.00% | 8 | 6.9 | 1,192 | 13,511 | 60.0% | 33.3% | |
| 75.00% | 8 | 6.5 | 815 | 15,293 | 0.0% | 85.7% | |
| 42.86% | 7 | 6.6 | 822 | 14,914 | 0.0% | 50.0% | |
| 16.67% | 6 | 6.9 | 944 | 8,718 | 20.0% | 0.0% | |
| 16.67% | 6 | 6.5 | 817 | 14,155 | 0.0% | 33.3% | |
| 0.00% | 6 | 6.7 | 779 | 10,927 | 0.0% | 0.0% | |
| 100.00% | 5 | 5.9 | 799 | 11,313 | 100.0% | 100.0% | |
| 40.00% | 5 | 6.2 | 854 | 16,166 | 0.0% | 40.0% | |
| 60.00% | 5 | 6.7 | 1,139 | 12,502 | 33.3% | 100.0% | |
| 20.00% | 5 | 6.8 | 752 | 14,238 | 50.0% | 0.0% | |
| 80.00% | 5 | 7.3 | 1,003 | 12,345 | 100.0% | 50.0% | |
| 60.00% | 5 | 6.7 | 653 | 13,925 | 100.0% | 33.3% | |
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Caitlyn vs Seraphine - Frequently Asked Questions
How does Caitlyn do against Seraphine in League of Legends?
Seraphine wins the Caitlyn vs Seraphine matchup with a 57.9% win rate compared to Caitlyn's 42.1%, a 15.8 percentage point difference. This data is based on 38 recent ranked games in patch 26.5.
How does Caitlyn do against Seraphine in the early game?
In the early game, Caitlyn has the advantage against Seraphine with a 50.0% win rate versus 50.0%. Caitlyn players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Caitlyn do against Seraphine in the late game?
In the late game, Seraphine takes over the Caitlyn vs Seraphine matchup with a 62.5% win rate compared to 37.5%. Seraphine scales better into team fights and objective contests after 25 minutes.
Who wins the Caitlyn vs Seraphine matchup?
Seraphine wins the matchup against Caitlyn with a 57.9% win rate in League of Legends patch 26.5. The 15.8 percentage point advantage means Seraphine is significantly favored in this lane matchup based on 38 games analyzed.
What is the best Caitlyn build against Seraphine?
The best Caitlyn build against Seraphine includes optimized core items. Check the matchup breakdown above for the full item path and build order.
What are the best Caitlyn runes against Seraphine?
The best Caitlyn runes against Seraphine use the Precision primary tree with Sorcery secondary. This rune setup achieves a 100.0% win rate in the Caitlyn vs Seraphine matchup. See the full rune breakdown in the matchup comparison above.
Does Caitlyn counter Seraphine?
No, Caitlyn struggles against Seraphine with only a 42.1% win rate. Seraphine has the advantage in this matchup. Caitlyn players should focus on safe farming and avoiding extended trades to minimize Seraphine's lead.
How do I play Caitlyn against Seraphine?
When playing Caitlyn against Seraphine, play cautiously and avoid Seraphine's power spikes. Look for jungle assistance and team-dependent plays since Seraphine has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.