- Win Rate
- 48.3%
- Pick Rate
- 6.2%
- Ban Rate
- 22.1%
Caitlyn vs Vayne
- Patch
- 26.22
- Games
- 12,059
- Lane
- All Lanes
- Tier
- All Tiers
- Last Updated
- Nov 14, 2026 UTC
- Author
- Dakota Chinnick
- Methodology
- Data Methodology
Caitlyn vs Vayne (Bot): Caitlyn wins 50.6% of 811 ranked games over the last 2 patches (gold diff at 15: +596). Patch 26.22 build & runes.
Caitlyn50.6%
Caitlyn vs Vayne is an even matchup: Caitlyn wins 50.6% of 811 games, and the 95% range (47.1–54.0%) comfortably includes 50%.
Caitlyn Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Caitlyn performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who wins Caitlyn vs Vayne?
Caitlyn wins 50.6% of these games. With this many games the true rate is most likely between 47.1% and 54.0% (95% range).
- Expected
- 49.7% From both champions' overall Bot win rates
- Matchup effect
- +0.9 pts Observed minus expected
- Sample
- 811 games Lane: Bot · Patch 26.21–26.22
- vs patch 26.21
- +2.0 pts Within normal patch-to-patch noise
Lane: Bot · Ranked Solo/Duo & Flex · North America server · All ranks · Patch 26.21–26.22 · Oct 27 – Nov 14
The headline win rate covers patches 26.21–26.22 (811 games). The lane, game-length, build and rune sections below use patch 26.22 only (188 games).
Key takeaways
- Caitlyn vs Vayne is an even matchup: Caitlyn wins 50.6% of 811 games, and the 95% range (47.1–54.0%) comfortably includes 50%.
- Both champions' overall Bot win rates predict 49.7% for Caitlyn; the result is within the margin of error of that, so this matchup mostly reflects the two champions' general strength.
- Caitlyn usually wins the lane: 596 gold ahead of Vayne at 15 minutes on average (188 games with a 15-minute snapshot).
- Caitlyn players pick Health Scaling (defense) far more often against Vayne: 74.6% of their other Bot games, 87.8% here.
How we calculate this
Games: ranked Solo/Duo and Flex games on the North America server from the patch shown. Remakes (games under 5 minutes) are excluded.
A game only counts when Caitlyn and Vayne played the same position on opposite teams, so roaming, lane swaps within a team or a champion merely being in the same game never count as this matchup.
The 95% range is a Wilson score interval. Confidence comes from how wide that range is: within ±3 points is very high, ±5 high, ±8 moderate, anything wider low. Below 20 games a matchup is not classified at all.
Expected win rate combines both champions’ win rates in this lane (same games and filters) with the log5 formula: E = A(1−B) / (A(1−B) + B(1−A)). Matchup effect = observed − expected.
"What changes" compares Caitlyn's choices in this matchup with the same champion's other games in the same lane, and lists a change only when it is at least 3 points and statistically significant (two-proportion z-test, |z| ≥ 2, 20+ games).
Results are not split by rank: the sample per rank is too small for honest per-rank matchup numbers.
Caitlyn vs Vayne Laning Stats
At 15 minutes
Whole-game averages
Caitlyn vs Vayne Win Rate by Game Length
Caitlyn's win rate against Vayne by game length. The dot is the win rate, the bar its 95% range and the dashed line the champion's usual win rate at that length. Lengths with fewer than 25 games are left blank.
No game length stands out: Caitlyn's results against Vayne in short and long games are within the margin of error of each other.
Caitlyn vs Vayne Power Spikes
Who is ahead at each stage, measured from these games. A stage reads "Even" when the difference is inside the margin of error, and "Insufficient data" when there are too few games to tell.
- Lane (15 min)CaitlynCaitlyn gold at 15: +596
- First itemCaitlynCaitlyn: 10.6 min · Vayne: 13.7 min
- Games under 20 minInsufficient data
- 20–30 min gamesEvenCaitlyn wins 51.8% of 85 games
- 30+ min gamesEvenCaitlyn wins 55.7% of 88 games
What Caitlyn Changes Against Vayne
Choices Caitlyn players make noticeably more or less often in this matchup than in their other Bot games.
Health Scaling (defense)Stat shardUsually74.6%vs Vayne87.8%+13.1 pts50.9% WR here- Health (defense)Stat shardUsually24.3%vs Vayne11.7%−12.6 pts63.6% WR here
Absolute FocusRuneUsually77.2%vs Vayne87.8%+10.6 pts50.9% WR here
Cut DownRuneUsually26.4%vs Vayne16.0%−10.4 pts50.0% WR here
Gathering StormRuneUsually78.2%vs Vayne88.3%+10.1 pts50.6% WR here
InspirationSecondary treeUsually18.5%vs Vayne8.5%−10.0 pts
SorcerySecondary treeUsually78.8%vs Vayne88.8%+10.0 pts50.3% WR here
Flash + BarrierSummoner spellsUsually81.4%vs Vayne90.4%+9.0 pts51.2% WR here
Best Caitlyn Build vs Vayne
Usual Caitlyn build (Bot)
90.0% win rate · 10 games
Against Vayne
Not enough matchup-specific build data: only 14 of 119 Caitlyn games against Vayne carried a complete build, which is too few to recommend an item path from. Use Caitlyn's standard build instead.
- Caitlyn usually completes Hexoptics C44 first, at 10.6 min (median of 99 games).
- Vayne usually completes Blade of The Ruined King first, at 13.7 min (median of 100 games).
- Skill priority: Q > W > E — the same as usual.
Builds are ranked by the lower edge of their win rate range, not the raw win rate, so a build seen in a handful of wins never outranks a proven one.
Best Caitlyn Runes vs Vayne
Usual Caitlyn runes (Bot)
Lethal Tempo
73.9% win rate · 23 games
Against Vayne
Lethal Tempo
50.5% win rate · 111 games
Plan your Caitlyn draft in Draft Lab
Draft Lab lays out both teams lane by lane with live matchup win rates, damage profiles and game-phase lean, and suggests picks and bans from current meta data.
- Full 5v5 draft board
- Lane matchup win rates
- Pick and ban suggestions
Caitlyn matchup data for League of Legends patch 26.22. The table below shows Caitlyn's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Caitlyn build, runes, laning stats, and early vs late game analysis for that specific matchup.
Other Caitlyn Matchups
Hardest for Caitlyn
Easiest for Caitlyn
Win rate and games for each matchup. Lists are ranked by the edge of the 95% range so small samples cannot top them; matchups with at least 50 games only.
Help us maintain accuracy! If you notice incorrect stats, missing data, or any issues, your feedback directly improves the quality of our data for the entire community.
Caitlyn vs Vayne FAQ - Patch 26.21–26.22
Who wins Caitlyn vs Vayne?
Caitlyn vs Vayne is an even matchup: Caitlyn wins 50.6% of 811 games, and the 95% range (47.1–54.0%) comfortably includes 50%.
What is Caitlyn's win rate against Vayne?
Caitlyn wins 50.6% of 811 Bot games against Vayne on patch 26.21–26.22 (95% range 47.1–54.0%). Based on both champions' overall Bot win rates, 49.7% would be expected.
Does Caitlyn counter Vayne?
Not clearly. Caitlyn wins 50.6% of 811 games against Vayne, and the 95% range (47.1–54.0%) includes 50%, so neither champion reliably counters the other on current data.
Who wins lane, Caitlyn or Vayne?
Caitlyn usually wins the lane: 596 gold ahead of Vayne at 15 minutes on average (188 games with a 15-minute snapshot).
Does Caitlyn outscale Vayne?
Not measurably: Caitlyn's win rate against Vayne in games of 25 minutes or less and in longer games is within the margin of error of each other.
When is Vayne strongest against Caitlyn?
On current data there is no stage of the game where Vayne is ahead of Caitlyn beyond the margin of error.
What should Caitlyn build against Vayne?
There are not enough games for a matchup-specific core, so use Caitlyn's usual Bot core: Stormrazor, Yun Tal Wildarrows, Infinity Edge.
What runes should Caitlyn use against Vayne?
Lethal Tempo with Precision and Sorcery — 50.5% over 111 games against Vayne. The biggest change against Vayne: Health Scaling (defense) (74.6% usually, 87.8% here).