Karthusvs Nasus
Karthus vs Nasus is a decisive matchup in LoL patch 26.14. Nasus wins with a 61.5% win rate (+23.1%) over Karthus based on 13 games. Karthus wins the early laning phase while Nasus scales better into the late game. Below you'll find the best Karthus build, runes, laning stats, and strategies for the Karthus vs Nasus matchup.
Karthus Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Karthus performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Karthus vs Nasus Matchup?
Karthus vs Nasus Matchup Summary
The Karthus vs Nasus matchup is a decisive matchup in League of Legends ranked play. Based on 13 recent matches analyzed, Nasus wins with a 61.5% win rate compared to Karthus's 38.5%, giving Nasus a 23.1 percentage point advantage. Game phase dynamics play a critical role here: Karthus controls the early laning stage, but Nasus outscales as the game goes longer. The matchup shifts dramatically depending on game length — Karthus needs to press advantages before Nasus reaches their power spikes, while Nasus should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in sustain, where Nasus leads by 2,162 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Nasus has a strong advantage in this matchup. Karthus players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Nasus overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Karthus vs Nasus Laning Phase Breakdown
Karthus is favored during the laning phase against Nasus, winning 3 out of 5 key stat categories. Karthus holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.
Best Karthus Build Against Nasus
Sorcerer's Shoes is the optimal boots choice against Nasus, providing the mobility and stats Karthus needs most in this matchup. The top-performing core items for Karthus against Nasus are Liandry's Torment, Shadowflame and Blackfire Torch. This combination gives Karthus an effective balance of damage, survivability, and utility for the matchup. This build has a 33.3% win rate across 3 games. While the overall matchup may be difficult, this item path gives Karthus the best chance to compete against Nasus. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Karthus vs Nasus matchup.
Early Game vs Late Game
Karthus66.7%
Nasus33.3%Karthus30.0%Nasus70.0%Karthus dominates the early game (first 15 minutes) with a commanding 66.7% win rate — a 33.3 percentage point lead over Nasus. This lopsided early game means Karthus can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Nasus is far superior in the late game (25+ minutes), boasting a 70.0% win rate — 40.0 points above Karthus. Extended games heavily favor Nasus, whose kit and scaling make them a dominant force in team fights and objective control.
This matchup features a dramatic power shift: Karthus must aggressively press their early advantage and close out the game before Nasus reaches their scaling breakpoints. If Nasus survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.
Best Karthus Runes Against Nasus
Domination
Sorcery
The Domination and Sorcery rune setup gives Karthus the best tools to compete against Nasus in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.
Karthus matchup data for League of Legends patch 26.14. The table below shows Karthus's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Karthus build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 50.00% | 34 | 1.5 | 1,210 | 14,460 | 54.5% | 47.8% | |
| 53.85% | 26 | 1.7 | 1,107 | 13,353 | 75.0% | 44.4% | |
| 65.38% | 26 | 1.6 | 1,213 | 14,129 | 62.5% | 66.7% | |
| 42.86% | 21 | 1.6 | 1,273 | 14,869 | 62.5% | 30.8% | |
| 57.14% | 21 | 6.7 | 1,272 | 14,858 | 33.3% | 66.7% | |
| 66.67% | 21 | 6.9 | 1,369 | 14,650 | 75.0% | 61.5% | |
| 60.00% | 20 | 6.2 | 1,547 | 15,163 | 37.5% | 75.0% | |
| 47.37% | 19 | 2.3 | 1,299 | 12,041 | 37.5% | 54.5% | |
| 36.84% | 19 | 6.3 | 1,222 | 12,598 | 50.0% | 30.8% | |
| 63.16% | 19 | 1.3 | 1,189 | 12,550 | 66.7% | 61.5% | |
| 44.44% | 18 | 1.5 | 984 | 12,231 | 28.6% | 54.5% | |
| 41.18% | 17 | 1.3 | 1,174 | 13,393 | 50.0% | 36.4% | |
| 64.71% | 17 | 1.4 | 1,133 | 13,538 | 60.0% | 66.7% | |
| 58.82% | 17 | 6.1 | 1,296 | 12,023 | 28.6% | 80.0% | |
| 31.25% | 16 | 1.1 | 998 | 10,234 | 22.2% | 42.9% | |
| 37.50% | 16 | 1.2 | 1,036 | 11,549 | 22.2% | 57.1% | |
| 56.25% | 16 | 1.4 | 1,291 | 15,822 | 33.3% | 61.5% | |
| 53.33% | 15 | 3.8 | 1,155 | 13,363 | 71.4% | 37.5% | |
| 57.14% | 14 | 1.5 | 1,189 | 16,770 | 80.0% | 44.4% | |
| 71.43% | 14 | 1.1 | 1,317 | 14,691 | 60.0% | 77.8% | |
| 38.46% | 13 | 2.1 | 1,364 | 16,137 | 50.0% | 33.3% | |
| 69.23% | 13 | 1.7 | 1,109 | 14,294 | 50.0% | 77.8% | |
| 38.46% | 13 | 1.6 | 1,250 | 13,792 | 66.7% | 30.0% | |
| 38.46% | 13 | 1.9 | 1,012 | 13,363 | 40.0% | 37.5% | |
| 50.00% | 12 | 1.6 | 1,101 | 11,974 | 50.0% | 50.0% | |
| 50.00% | 12 | 1.3 | 1,075 | 13,070 | 60.0% | 42.9% | |
| 33.33% | 12 | 5.8 | 1,242 | 13,035 | 14.3% | 60.0% | |
| 36.36% | 11 | 1.2 | 1,173 | 13,470 | 40.0% | 33.3% | |
| 45.45% | 11 | 1.3 | 1,270 | 13,006 | 66.7% | 37.5% | |
| 45.45% | 11 | 1.4 | 1,198 | 14,745 | 50.0% | 44.4% | |
| 72.73% | 11 | 1.7 | 1,133 | 12,272 | 75.0% | 71.4% | |
| 40.00% | 10 | 6.4 | 1,245 | 14,255 | 50.0% | 37.5% | |
| 50.00% | 10 | 1.2 | 1,072 | 11,237 | 25.0% | 66.7% | |
| 60.00% | 10 | 3.8 | 1,326 | 16,244 | 100.0% | 55.6% | |
| 50.00% | 10 | 7.0 | 1,119 | 13,927 | 33.3% | 57.1% | |
| 50.00% | 10 | 6.1 | 1,271 | 14,647 | 0.0% | 62.5% | |
| 66.67% | 9 | 1.7 | 1,147 | 15,247 | 100.0% | 57.1% | |
| 77.78% | 9 | 6.6 | 1,162 | 14,764 | 66.7% | 83.3% | |
| 37.50% | 8 | 5.9 | 1,039 | 11,392 | 0.0% | 100.0% | |
| 87.50% | 8 | 4.1 | 1,125 | 12,351 | 75.0% | 100.0% | |
| 57.14% | 7 | 1.7 | 1,407 | 16,439 | 33.3% | 75.0% | |
| 57.14% | 7 | 6.8 | 1,189 | 13,558 | 50.0% | 60.0% | |
| 28.57% | 7 | 5.7 | 809 | 9,614 | 40.0% | 0.0% | |
| 71.43% | 7 | 5.3 | 1,423 | 15,641 | 0.0% | 83.3% | |
| 50.00% | 6 | 7.8 | 1,516 | 10,970 | 75.0% | 0.0% | |
| 16.67% | 6 | 6.8 | 1,068 | 9,349 | 25.0% | 0.0% | |
| 16.67% | 6 | 7.0 | 1,143 | 13,263 | 33.3% | 0.0% | |
| 66.67% | 6 | 5.7 | 1,156 | 11,144 | 0.0% | 100.0% | |
| 50.00% | 6 | 2.5 | 1,110 | 11,409 | 75.0% | 0.0% | |
| 66.67% | 6 | 7.5 | 1,511 | 18,224 | 0.0% | 80.0% | |
| 60.00% | 5 | 5.6 | 1,047 | 12,658 | 100.0% | 50.0% | |
| 60.00% | 5 | 1.4 | 1,361 | 15,802 | 0.0% | 75.0% | |
| 40.00% | 5 | 2.1 | 1,186 | 10,480 | 33.3% | 50.0% | |
| 60.00% | 5 | 2.3 | 1,128 | 14,944 | 0.0% | 75.0% | |
| 20.00% | 5 | 5.8 | 1,755 | 14,344 | 50.0% | 0.0% | |
| 40.00% | 5 | 7.0 | 1,629 | 11,364 | 66.7% | 0.0% | |
| 80.00% | 5 | 3.3 | 1,369 | 13,229 | 100.0% | 66.7% | |
| 40.00% | 5 | 3.2 | 1,676 | 13,066 | 50.0% | 33.3% | |
| 60.00% | 5 | 1.1 | 1,231 | 14,729 | 0.0% | 75.0% | |
| 100.00% | 2 | 1.5 | 1,218 | 14,599 | 100.0% | 100.0% | |
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Karthus vs Nasus - Frequently Asked Questions
How does Karthus do against Nasus in League of Legends?
Nasus wins the Karthus vs Nasus matchup with a 61.5% win rate compared to Karthus's 38.5%, a 23.1 percentage point difference. This data is based on 13 recent ranked games in patch 26.14.
How does Karthus do against Nasus in the early game?
In the early game, Karthus has the advantage against Nasus with a 66.7% win rate versus 33.3%. Karthus players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Karthus do against Nasus in the late game?
In the late game, Nasus takes over the Karthus vs Nasus matchup with a 70.0% win rate compared to 30.0%. Nasus scales better into team fights and objective contests after 25 minutes.
Who wins the Karthus vs Nasus matchup?
Nasus wins the matchup against Karthus with a 61.5% win rate in League of Legends patch 26.14. The 23.1 percentage point advantage means Nasus is significantly favored in this lane matchup based on 13 games analyzed.
What is the best Karthus build against Nasus?
The best Karthus build against Nasus includes Liandry's Torment, Shadowflame, Blackfire Torch with Sorcerer's Shoes. This build achieves a 33.3% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.
What are the best Karthus runes against Nasus?
The best Karthus runes against Nasus use the Domination primary tree with Sorcery secondary. This rune setup achieves a 60.0% win rate in the Karthus vs Nasus matchup. See the full rune breakdown in the matchup comparison above.
Does Karthus counter Nasus?
No, Karthus struggles against Nasus with only a 38.5% win rate. Nasus has the advantage in this matchup. Karthus players should focus on safe farming and avoiding extended trades to minimize Nasus's lead.
How do I play Karthus against Nasus?
When playing Karthus against Nasus, play cautiously and avoid Nasus's power spikes. Look for jungle assistance and team-dependent plays since Nasus has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.