Lissandra - League of Legends Champion
Win Rate
51.3%
Pick Rate
1.9%

Lissandravs Pyke

AMage
Patch26.10
Matches788,689
LaneAll Lanes
TierAll Tiers
Last UpdatedMay 18, 2026
MethodologyData Methodology

Lissandra vs Pyke is a decisive matchup in LoL patch 26.10. Pyke wins with a 80.0% win rate (+60.0%) over Lissandra based on 5 games. Lissandra wins the early laning phase while Pyke scales better into the late game. Below you'll find the best Lissandra build, runes, laning stats, and strategies for the Lissandra vs Pyke matchup.

Lissandra Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Lissandra performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Pyke - 20.0% win ratePyke(20.0%)
Lissandra - 20.0% win rate in this matchup
Lissandra
20.0% WR
VS
Pyke vs Lissandra matchup - 80.0% win rate
Pyke
80.0% WR

Who Wins the Lissandra vs Pyke Matchup?

Pyke wins the Lissandra vs Pyke matchup
Winner
Pyke
Matches: 5
20.0%
Win Rate
80.0%
1.8
CS / min
1.3
564
DMG / min
524
8,399
Gold / game
8,752
132
Heal / min
202
480
DMG Mitigated / min
357
2.0
CC / min
0.9
50.0%
Early Game WR
50.0%
0.0%
Late Game WR
100.0%

Lissandra vs Pyke Matchup Summary

The Lissandra vs Pyke matchup is a decisive matchup in League of Legends ranked play. Based on 5 recent matches analyzed, Pyke wins with a 80.0% win rate compared to Lissandra's 20.0%, giving Pyke a 60.0 percentage point advantage. Game phase dynamics play a critical role here: Lissandra controls the early laning stage, but Pyke outscales as the game goes longer. The matchup shifts dramatically depending on game length — Lissandra needs to press advantages before Pyke reaches their power spikes, while Pyke should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Lissandra leads by 1.2s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Pyke has a strong advantage in this matchup. Lissandra players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Pyke overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Lissandra vs Pyke Laning Phase Breakdown

Lissandra wins the laning phase against Pyke in League of Legends

Lissandra is favored during the laning phase against Pyke, winning 4 out of 5 key stat categories. Lissandra holds advantages in farming, damage, crowd control and sustain, making them the stronger laner in this matchup.

Farming
1.8Lissandra
1.3Pyke
Lissandra edges out Pyke by 0.5 CS per minute — a moderate farming advantage that adds up to roughly 8 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Lissandra.
Damage
564Lissandra
524Pyke
Lissandra deals 40 more champion damage per minute than Pyke. While noticeable in extended trades, this gap can be offset by Pyke choosing favorable fight windows, such as engaging when Lissandra's key abilities are on cooldown or trading immediately after dodging a skillshot.
Economy
8,399Lissandra
8,752Pyke
Pyke earns 354 more gold per game than Lissandra, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Pyke slightly faster item completions.
Utility
2.0Lissandra
0.9Pyke
Lissandra brings significantly more crowd control than Pyke, with 1.2 more seconds of CC per minute. This large utility gap makes Lissandra far more valuable in setting up jungle ganks, controlling objectives, and locking down targets in team fights. Pyke should invest in tenacity and position carefully to avoid being chain-CC'd.
Sustain
612Lissandra
559Pyke
Lissandra heals and mitigates 53 more damage per minute than Pyke, providing moderate extra durability. This sustain edge allows Lissandra to stay in lane longer between recalls and gradually win extended wars of attrition. Consider building early grievous wounds if playing Pyke.

Best Lissandra Build Against Pyke

Mercury's Treads is the optimal boots choice against Pyke, providing the mobility and stats Lissandra needs most in this matchup. The top-performing core items for Lissandra against Pyke are Zhonya's Hourglass, Malignance and Seraph's Embrace. This combination gives Lissandra an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Lissandra vs Pyke matchup.

Early Game vs Late Game

Early Game
Lissandra
50.0%
+0.0% advantage
Lissandra early game win rateLissandra50.0%
Pyke early game win ratePyke50.0%
Late Game
Pyke
100.0%
+100.0% advantage
Lissandra late game win rateLissandra0.0%
Pyke late game win ratePyke100.0%

The early game (first 15 minutes) is a toss-up between Lissandra and Pyke, with Lissandra holding a razor-thin 50.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.

Pyke is far superior in the late game (25+ minutes), boasting a 100.0% win rate — 100.0 points above Lissandra. Extended games heavily favor Pyke, whose kit and scaling make them a dominant force in team fights and objective control.

The power dynamics shift as the game progresses — Lissandra has the edge early, but Pyke gradually takes over. However, the margins are slim enough that either champion can win at any stage with the right plays. Focus on taking advantages when you have them rather than waiting for a specific game phase.

Best Lissandra Runes Against Pyke

Domination rune tree - Lissandra primary runes vs PykeDomination
Electrocute - best Lissandra rune vs PykeCheap Shot - best Lissandra rune vs PykeGrisly Mementos - best Lissandra rune vs PykeUltimate Hunter - best Lissandra rune vs Pyke
Inspiration rune tree - Lissandra secondary runes vs PykeInspiration
Biscuit Delivery - best Lissandra rune vs PykeCosmic Insight - best Lissandra rune vs Pyke
100.0% WR

The Domination and Inspiration rune setup gives Lissandra the best tools to compete against Pyke in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Lissandra matchup data for League of Legends patch 26.10. The table below shows Lissandra's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Lissandra build, runes, laning stats, and early vs late game analysis for that specific matchup.

Lissandra matchup win rates and stats in League of Legends patch 26.10
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
52.05%1716.676911,31151.3%52.8%
56.96%1586.883812,10962.9%53.1%
56.25%1446.880212,07560.0%53.9%
57.35%1366.585111,77743.3%68.4%
54.17%1206.689411,83858.7%51.4%
52.10%1196.675911,54458.0%47.8%
50.55%916.886411,83342.9%55.4%
50.00%866.076311,36348.6%51.0%
49.40%836.668210,75635.1%60.9%
53.09%816.894512,08459.5%47.7%
48.65%746.587012,07565.5%37.8%
44.44%726.480011,90248.0%42.5%
40.30%676.679112,26054.2%32.6%
41.07%567.091010,56442.9%39.3%
43.75%486.492611,68442.9%44.4%
45.83%486.976410,31648.1%42.9%
44.68%477.191310,27446.1%42.9%
48.89%456.774111,85055.6%44.4%
56.82%446.680710,71460.0%52.6%
47.50%406.888911,81435.7%53.9%
52.50%406.580111,07859.1%44.4%
48.72%396.379410,53757.9%40.0%
54.05%376.289411,67847.1%60.0%
48.65%376.884212,04869.2%37.5%
52.78%366.577912,44260.0%50.0%
50.00%346.67739,95460.0%42.1%
50.00%346.789912,47850.0%50.0%
59.38%326.685112,14046.1%68.4%
43.75%326.373511,21155.6%39.1%
62.50%327.089211,23666.7%58.8%
35.48%316.790111,72750.0%28.6%
33.33%305.891912,36750.0%25.0%
36.67%306.988112,31350.0%31.8%
51.72%296.881710,56962.5%38.5%
51.72%296.979211,75670.0%42.1%
53.85%266.279111,44255.6%52.9%
61.54%266.881611,31671.4%50.0%
50.00%226.884211,41060.0%41.7%
45.45%227.184710,22553.9%33.3%
61.90%215.885210,29258.3%66.7%
55.00%205.780510,44766.7%45.5%
35.00%206.567211,29344.4%27.3%
26.32%195.971112,06425.0%27.3%
41.18%176.976510,63760.0%14.3%
70.59%176.589712,69080.0%66.7%
43.75%163.559310,75350.0%41.7%
66.67%157.092911,70940.0%80.0%
53.33%156.783211,82150.0%57.1%
66.67%156.676910,95857.1%75.0%
60.00%156.888914,333100.0%50.0%
66.67%157.490412,42385.7%50.0%
42.86%143.885213,75866.7%36.4%
38.46%136.384413,80350.0%36.4%
69.23%135.977812,797100.0%60.0%
66.67%126.786011,77966.7%66.7%
41.67%126.888512,73525.0%50.0%
72.73%117.486911,82080.0%66.7%
36.36%116.399712,01833.3%40.0%
50.00%106.874311,79066.7%25.0%
22.22%91.54868,3950.0%33.3%
33.33%96.773911,320100.0%14.3%
33.33%97.577010,76266.7%16.7%
55.56%96.91,07811,74633.3%66.7%
22.22%97.082511,61320.0%25.0%
66.67%96.189612,85166.7%66.7%
22.22%95.776010,70850.0%14.3%
37.50%82.05567,33950.0%0.0%
37.50%87.594613,49166.7%20.0%
37.50%87.391710,19520.0%66.7%
50.00%82.75139,630100.0%33.3%
50.00%87.31,05311,45750.0%50.0%
25.00%86.882811,86333.3%20.0%
57.14%72.462312,2880.0%57.1%
85.71%76.499811,349100.0%75.0%
28.57%75.272210,611100.0%16.7%
71.43%77.094211,67033.3%100.0%
57.14%76.57077,45375.0%33.3%
28.57%77.01,20012,84850.0%20.0%
83.33%66.993211,04975.0%100.0%
83.33%67.61,02412,158100.0%66.7%
50.00%66.785513,791100.0%40.0%
33.33%67.094112,15450.0%25.0%
16.67%66.399410,56850.0%0.0%
33.33%66.278310,96850.0%25.0%
66.67%64.367711,77250.0%75.0%
40.00%52.05108,11966.7%0.0%
80.00%55.390610,607100.0%50.0%
40.00%54.367511,12850.0%33.3%
60.00%56.28127,81460.0%0.0%
20.00%51.85648,39950.0%0.0%
80.00%56.86467,52875.0%100.0%
60.00%57.463411,653100.0%50.0%
60.00%52.46207,49933.3%100.0%
60.00%53.77858,70650.0%66.7%
0.00%56.675011,4390.0%0.0%
60.00%55.878911,40250.0%66.7%
60.00%53.84173,79660.0%0.0%
40.00%56.37717,0390.0%100.0%

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Lissandra vs Pyke - Frequently Asked Questions

How does Lissandra do against Pyke in League of Legends?

Pyke wins the Lissandra vs Pyke matchup with a 80.0% win rate compared to Lissandra's 20.0%, a 60.0 percentage point difference. This data is based on 5 recent ranked games in patch 26.10.

How does Lissandra do against Pyke in the early game?

In the early game, Lissandra has the advantage against Pyke with a 50.0% win rate versus 50.0%. Lissandra players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Lissandra do against Pyke in the late game?

In the late game, Pyke takes over the Lissandra vs Pyke matchup with a 100.0% win rate compared to 0.0%. Pyke scales better into team fights and objective contests after 25 minutes.

Who wins the Lissandra vs Pyke matchup?

Pyke wins the matchup against Lissandra with a 80.0% win rate in League of Legends patch 26.10. The 60.0 percentage point advantage means Pyke is significantly favored in this lane matchup based on 5 games analyzed.

What is the best Lissandra build against Pyke?

The best Lissandra build against Pyke includes Zhonya's Hourglass, Malignance, Seraph's Embrace with Mercury's Treads. Check the matchup breakdown above for the full item path and build order.

What are the best Lissandra runes against Pyke?

The best Lissandra runes against Pyke use the Domination primary tree with Inspiration secondary. This rune setup achieves a 100.0% win rate in the Lissandra vs Pyke matchup. See the full rune breakdown in the matchup comparison above.

Does Lissandra counter Pyke?

No, Lissandra struggles against Pyke with only a 20.0% win rate. Pyke has the advantage in this matchup. Lissandra players should focus on safe farming and avoiding extended trades to minimize Pyke's lead.

How do I play Lissandra against Pyke?

When playing Lissandra against Pyke, play cautiously and avoid Pyke's power spikes. Look for jungle assistance and team-dependent plays since Pyke has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.