Lissandra - League of Legends Champion
Win Rate
51.3%
Pick Rate
2.2%

Lissandravs Annie

AMage
Patch26.7
Matches949,984
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 21, 2026
MethodologyData Methodology

Lissandra vs Annie is a decisive matchup in LoL patch 26.7. Lissandra wins with a 66.7% win rate (+33.3%) over Annie based on 24 games. Lissandra holds the advantage in both the early and late game. Below you'll find the best Lissandra build, runes, laning stats, and strategies for the Lissandra vs Annie matchup.

Lissandra Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Lissandra performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Annie - 66.7% win rateAnnie(66.7%)
Lissandra - 66.7% win rate in this matchup
Lissandra
66.7% WR
VS
Annie vs Lissandra matchup - 33.3% win rate
Annie
33.3% WR

Who Wins the Lissandra vs Annie Matchup?

Lissandra wins the Lissandra vs Annie matchup
Winner
Lissandra
Matches: 24
66.7%
Win Rate
33.3%
7.1
CS / min
6.3
788
DMG / min
875
11,244
Gold / game
10,525
161
Heal / min
70
404
DMG Mitigated / min
461
1.5
CC / min
0.9
54.5%
Early Game WR
45.5%
76.9%
Late Game WR
23.1%

Lissandra vs Annie Matchup Summary

The Lissandra vs Annie matchup is a decisive matchup in League of Legends ranked play. Based on 24 recent matches analyzed, Lissandra wins with a 66.7% win rate compared to Annie's 33.3%, giving Lissandra a 33.3 percentage point advantage. Lissandra dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Annie players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Lissandra leads by 0.5s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Lissandra players can confidently pick into Annie and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Annie away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Lissandra vs Annie Laning Phase Breakdown

Lissandra wins the laning phase against Annie in League of Legends

Lissandra is favored during the laning phase against Annie, winning 4 out of 5 key stat categories. Lissandra holds advantages in farming, gold income, crowd control and sustain, making them the stronger laner in this matchup.

Farming
7.1Lissandra
6.3Annie
Lissandra significantly out-farms Annie by 0.9 CS per minute, accumulating an estimated 13 CS lead by mid game. This substantial farming gap gives Lissandra a major gold advantage and earlier item completions. Annie players should prioritize wave management techniques like freezing near tower and using abilities efficiently to minimize the deficit.
Damage
788Lissandra
875Annie
Annie heavily out-damages Lissandra by 87 DMG/min, dominating both short trades and all-in fights. Lissandra should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Annie's sustained damage advantage take over.
Economy
11,244Lissandra
10,525Annie
Lissandra earns 719 more gold per game than Annie, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Lissandra slightly faster item completions.
Utility
1.5Lissandra
0.9Annie
Lissandra provides 0.5 seconds more crowd control per minute than Annie, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Lissandra coordinate with their jungler and control the pace of skirmishes.
Sustain
564Lissandra
531Annie
Lissandra and Annie have comparable sustain profiles, with only 34 HP/min separating their healing and damage mitigation. Neither champion can out-attrition the other in lane, so trades will be decided by burst potential and ability usage rather than sustain.

Best Lissandra Build Against Annie

Spellslinger's Shoes is the optimal boots choice against Annie, providing the mobility and stats Lissandra needs most in this matchup. The top-performing core items for Lissandra against Annie are Shadowflame, Zhonya's Hourglass and Malignance. This combination gives Lissandra an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 60.0% win rate across 5 games — well above average and making it the top item path against Annie. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Lissandra vs Annie matchup.

Early Game vs Late Game

Early Game
Lissandra
54.5%
+9.1% advantage
Lissandra early game win rateLissandra54.5%
Annie early game win rateAnnie45.5%
Late Game
Lissandra
76.9%
+53.8% advantage
Lissandra late game win rateLissandra76.9%
Annie late game win rateAnnie23.1%

Lissandra dominates the early game (first 15 minutes) with a commanding 54.5% win rate — a 9.1 percentage point lead over Annie. This lopsided early game means Lissandra can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Lissandra is far superior in the late game (25+ minutes), boasting a 76.9% win rate — 53.8 points above Annie. Extended games heavily favor Lissandra, whose kit and scaling make them a dominant force in team fights and objective control.

Lissandra holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Annie players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Lissandra Runes Against Annie

Sorcery rune tree - Lissandra primary runes vs AnnieSorcery
Arcane Comet - best Lissandra rune vs AnnieManaflow Band - best Lissandra rune vs AnnieTranscendence - best Lissandra rune vs AnnieScorch - best Lissandra rune vs Annie
Domination rune tree - Lissandra secondary runes vs AnnieDomination
Cheap Shot - best Lissandra rune vs AnnieUltimate Hunter - best Lissandra rune vs Annie
80.0% WR

Running Sorcery primary with Domination secondary allows Lissandra to press their advantage against Annie, amplifying the strengths that make this a favorable matchup.


Lissandra matchup data for League of Legends patch 26.7. The table below shows Lissandra's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Lissandra build, runes, laning stats, and early vs late game analysis for that specific matchup.

Lissandra matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
60.00%1306.883712,37853.6%64.9%
57.52%1136.882011,83565.2%52.2%
50.00%766.890711,85747.2%52.5%
45.95%746.778211,93537.5%52.4%
47.95%736.982512,39648.3%47.7%
52.11%717.081212,61135.7%62.8%
53.62%696.788911,32658.1%50.0%
54.55%666.798912,99555.2%54.0%
50.00%626.990112,04736.7%62.5%
54.10%616.687711,06545.5%64.3%
57.38%616.276711,40053.6%60.6%
34.48%586.766810,83031.4%39.1%
40.00%556.372811,33333.3%45.2%
46.94%496.975711,65340.0%51.7%
50.00%486.776511,97850.0%50.0%
50.00%406.476411,31941.2%56.5%
65.00%407.283311,56863.6%66.7%
56.41%397.084511,79244.4%66.7%
60.00%356.876110,99150.0%70.6%
48.57%356.881511,55440.0%55.0%
36.36%336.784111,39846.7%27.8%
21.21%336.478711,43923.1%20.0%
63.33%307.380811,58476.5%46.1%
62.07%297.188313,06883.3%47.1%
58.62%296.596211,72763.6%55.6%
53.57%286.983410,91262.5%41.7%
46.43%286.68679,78147.1%45.5%
53.57%286.881411,53950.0%56.3%
59.26%277.079712,15157.1%61.5%
69.23%266.586913,22971.4%68.4%
57.69%266.679612,06775.0%42.9%
40.00%257.276711,82854.5%28.6%
64.00%256.680511,12450.0%73.3%
41.67%246.992712,63340.0%42.9%
66.67%247.178811,24454.5%76.9%
73.68%197.196712,77550.0%90.9%
44.44%187.31,06512,47460.0%25.0%
64.71%177.290311,48980.0%42.9%
33.33%156.473710,70622.2%50.0%
57.14%146.289412,26342.9%71.4%
42.86%147.375110,43150.0%25.0%
76.92%136.783113,11175.0%77.8%
38.46%136.082212,47860.0%25.0%
30.77%136.896711,40720.0%37.5%
15.38%136.584811,09216.7%14.3%
45.45%116.480812,11440.0%50.0%
27.27%116.792811,21620.0%33.3%
54.55%116.888611,95450.0%57.1%
40.00%106.882512,83166.7%28.6%
50.00%106.452910,44128.6%100.0%
55.56%96.295114,28150.0%57.1%
88.89%97.280612,70675.0%100.0%
55.56%97.288211,46775.0%40.0%
55.56%95.672312,03950.0%60.0%
55.56%97.786112,78766.7%50.0%
75.00%87.487510,71080.0%66.7%
57.14%77.387510,78575.0%33.3%
42.86%75.873510,32566.7%25.0%
85.71%77.087111,26283.3%100.0%
71.43%76.173511,33280.0%50.0%
50.00%61.761410,6240.0%60.0%
83.33%67.91,14313,99850.0%100.0%
33.33%67.796512,2420.0%66.7%
33.33%66.686711,32825.0%50.0%
50.00%62.45439,94466.7%33.3%
83.33%67.183312,020100.0%80.0%
16.67%67.26078,27816.7%0.0%
60.00%56.01,16411,19766.7%50.0%
40.00%53.07276,78640.0%0.0%
20.00%57.793410,62525.0%0.0%
20.00%55.05978,21425.0%0.0%
40.00%53.45178,76125.0%100.0%
80.00%55.064712,91850.0%100.0%
40.00%56.783411,7270.0%66.7%
60.00%56.077611,837100.0%33.3%
40.00%56.374111,1560.0%50.0%
60.00%56.897912,10050.0%66.7%
80.00%56.51,08510,600100.0%66.7%

Get the MetaBot Desktop App

Level up your gameplay with real-time overlays, automatic game detection, and instant stats — all on your desktop.

In-game overlaysAuto game detectionMulti-game supportPersonal dashboard
Download NowFree download
🔍

Help us maintain accuracy! If you notice incorrect stats, missing data, or any issues, your feedback directly improves the quality of our data for the entire community.

Report an Issue

Lissandra vs Annie - Frequently Asked Questions

How does Lissandra do against Annie in League of Legends?

Lissandra wins the Lissandra vs Annie matchup with a 66.7% win rate compared to Annie's 33.3%, a 33.3 percentage point difference. This data is based on 24 recent ranked games in patch 26.7.

How does Lissandra do against Annie in the early game?

In the early game, Lissandra has the advantage against Annie with a 54.5% win rate versus 45.5%. Lissandra players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Lissandra do against Annie in the late game?

In the late game, Lissandra takes over the Lissandra vs Annie matchup with a 76.9% win rate compared to 23.1%. Lissandra scales better into team fights and objective contests after 25 minutes.

Who wins the Lissandra vs Annie matchup?

Lissandra wins the matchup against Annie with a 66.7% win rate in League of Legends patch 26.7. The 33.3 percentage point advantage means Lissandra is significantly favored in this lane matchup based on 24 games analyzed.

What is the best Lissandra build against Annie?

The best Lissandra build against Annie includes Shadowflame, Zhonya's Hourglass, Malignance with Spellslinger's Shoes. This build achieves a 60.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Lissandra runes against Annie?

The best Lissandra runes against Annie use the Sorcery primary tree with Domination secondary. This rune setup achieves a 80.0% win rate in the Lissandra vs Annie matchup. See the full rune breakdown in the matchup comparison above.

Does Lissandra counter Annie?

Yes, Lissandra has a favorable matchup against Annie with a 66.7% win rate. Lissandra strongly counters Annie in lane based on current patch 26.7 data.

How do I play Lissandra against Annie?

When playing Lissandra against Annie, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.