Nasus - League of Legends Champion
Win Rate
52.9%
Pick Rate
4.2%

Nasusvs Lissandra

SFighterTank
Patch26.5
Matches469,660
LaneAll Lanes
TierAll Tiers
Last UpdatedMar 12, 2026
MethodologyData Methodology

Nasus vs Lissandra is a decisive matchup in LoL patch 26.5. Lissandra wins with a 57.1% win rate (+14.3%) over Nasus based on 7 games. Nasus wins the early laning phase while Lissandra scales better into the late game. Below you'll find the best Nasus build, runes, laning stats, and strategies for the Nasus vs Lissandra matchup.

Nasus Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Nasus performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Lissandra - 42.9% win rateLissandra(42.9%)
Nasus - 42.9% win rate in this matchup
Nasus
42.9% WR
VS
Lissandra vs Nasus matchup - 57.1% win rate
Lissandra
57.1% WR

Who Wins the Nasus vs Lissandra Matchup?

Lissandra wins the Nasus vs Lissandra matchup
Winner
Lissandra
Matches: 7
42.9%
Win Rate
57.1%
6.5
CS / min
6.9
667
DMG / min
1,038
9,328
Gold / game
9,894
504
Heal / min
198
1,731
DMG Mitigated / min
564
0.7
CC / min
2.3
66.7%
Early Game WR
33.3%
25.0%
Late Game WR
75.0%

Nasus vs Lissandra Matchup Summary

The Nasus vs Lissandra matchup is a decisive matchup in League of Legends ranked play. Based on 7 recent matches analyzed, Lissandra wins with a 57.1% win rate compared to Nasus's 42.9%, giving Lissandra a 14.3 percentage point advantage. Game phase dynamics play a critical role here: Nasus controls the early laning stage, but Lissandra outscales as the game goes longer. The matchup shifts dramatically depending on game length — Nasus needs to press advantages before Lissandra reaches their power spikes, while Lissandra should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Lissandra leads by 1.5s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Lissandra has a strong advantage in this matchup. Nasus players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Lissandra overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Nasus vs Lissandra Laning Phase Breakdown

Lissandra wins the laning phase against Nasus in League of Legends

Lissandra is favored during the laning phase against Nasus, winning 4 out of 5 key stat categories. Lissandra holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.

Farming
6.5Nasus
6.9Lissandra
Lissandra edges out Nasus by 0.4 CS per minute — a moderate farming advantage that adds up to roughly 6 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Lissandra.
Damage
667Nasus
1,038Lissandra
Lissandra heavily out-damages Nasus by 372 DMG/min, dominating both short trades and all-in fights. Nasus should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Lissandra's sustained damage advantage take over.
Economy
9,328Nasus
9,894Lissandra
Lissandra earns 566 more gold per game than Nasus, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Lissandra slightly faster item completions.
Utility
0.7Nasus
2.3Lissandra
Lissandra brings significantly more crowd control than Nasus, with 1.5 more seconds of CC per minute. This large utility gap makes Lissandra far more valuable in setting up jungle ganks, controlling objectives, and locking down targets in team fights. Nasus should invest in tenacity and position carefully to avoid being chain-CC'd.
Sustain
2,235Nasus
762Lissandra
Nasus vastly out-sustains Lissandra, healing and mitigating 1,474 more damage per minute. This massive durability gap means Nasus can absorb significant punishment and remain in lane while Lissandra is forced to recall. Building grievous wounds early is essential for Lissandra, and focusing on burst trade patterns rather than sustained fights is critical.

Best Nasus Build Against Lissandra

Mercury's Treads is the optimal boots choice against Lissandra, providing the mobility and stats Nasus needs most in this matchup. The top-performing core items for Nasus against Lissandra are Death's Dance, Essence Reaver and Fiendhunter Bolts. This combination gives Nasus an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Nasus vs Lissandra matchup.

Early Game vs Late Game

Early Game
Nasus
66.7%
+33.3% advantage
Nasus early game win rateNasus66.7%
Lissandra early game win rateLissandra33.3%
Late Game
Lissandra
75.0%
+50.0% advantage
Nasus late game win rateNasus25.0%
Lissandra late game win rateLissandra75.0%

Nasus dominates the early game (first 15 minutes) with a commanding 66.7% win rate — a 33.3 percentage point lead over Lissandra. This lopsided early game means Nasus can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Lissandra is far superior in the late game (25+ minutes), boasting a 75.0% win rate — 50.0 points above Nasus. Extended games heavily favor Lissandra, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Nasus must aggressively press their early advantage and close out the game before Lissandra reaches their scaling breakpoints. If Lissandra survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Nasus Runes Against Lissandra

Precision rune tree - Nasus primary runes vs LissandraPrecision
Fleet Footwork - best Nasus rune vs LissandraPresence of Mind - best Nasus rune vs LissandraLegend: Alacrity - best Nasus rune vs LissandraLast Stand - best Nasus rune vs Lissandra
Resolve rune tree - Nasus secondary runes vs LissandraResolve
Second Wind - best Nasus rune vs LissandraUnflinching - best Nasus rune vs Lissandra
100.0% WR

The Precision and Resolve rune setup gives Nasus the best tools to compete against Lissandra in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Nasus matchup data for League of Legends patch 26.5. The table below shows Nasus's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Nasus build, runes, laning stats, and early vs late game analysis for that specific matchup.

Nasus matchup win rates and stats in League of Legends patch 26.5
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
44.30%2286.375611,75035.6%51.2%
52.54%1185.673811,73654.5%51.4%
53.51%1145.881412,06047.7%57.1%
50.00%985.71,18812,16153.3%47.2%
51.61%935.762412,03556.3%49.2%
59.14%935.184311,75262.2%56.3%
37.36%916.371411,07232.6%41.7%
65.56%907.286812,94562.5%68.0%
48.86%886.282111,43959.2%35.9%
56.32%876.671512,25063.2%51.0%
44.30%795.177612,20050.0%39.5%
51.35%745.081112,03637.5%61.9%
50.68%736.270911,87438.9%62.2%
51.39%726.677212,27654.8%48.8%
37.14%706.366011,25737.5%36.8%
48.53%686.682212,22544.0%51.2%
55.22%675.164611,17054.3%56.3%
56.25%646.194812,39044.8%65.7%
50.00%626.079811,43956.7%43.8%
51.61%626.187811,91655.2%48.5%
60.00%606.085211,61656.7%63.3%
55.93%596.283311,70164.0%50.0%
53.57%566.578213,05365.4%43.3%
48.21%565.867710,94953.1%41.7%
54.55%556.784012,66144.4%64.3%
39.62%531.865511,56052.2%30.0%
57.69%525.770911,65866.7%50.0%
60.78%516.273912,17081.0%46.7%
52.94%515.375511,13651.9%54.2%
58.00%505.581111,96663.6%53.6%
47.83%466.267812,84852.2%43.5%
64.44%456.463311,51156.3%69.0%
47.73%445.465612,18237.5%53.6%
53.49%433.066312,91258.8%50.0%
54.76%426.875211,71050.0%60.0%
58.54%412.682211,71554.2%64.7%
62.50%401.473613,07452.6%71.4%
50.00%406.684412,99440.0%56.0%
47.50%402.470413,58643.8%50.0%
61.54%392.280713,16758.3%63.0%
56.76%376.568112,01655.0%58.8%
48.65%375.983511,32753.9%45.8%
52.94%346.677312,40953.3%52.6%
45.45%336.468910,84626.7%61.1%
48.28%297.171110,63625.0%76.9%
62.07%296.697511,43762.5%61.5%
60.71%282.271912,43942.9%78.6%
55.56%273.083712,97866.7%46.7%
46.15%266.371311,96354.5%40.0%
48.00%251.889013,17254.5%42.9%
45.83%246.078511,49377.8%26.7%
60.87%236.267111,82455.6%64.3%
73.91%236.471812,22080.0%69.2%
54.55%226.161610,56550.0%60.0%
54.55%222.784812,56654.5%54.5%
50.00%224.287513,25660.0%41.7%
61.90%212.084114,46983.3%53.3%
52.38%216.876912,44650.0%53.9%
70.00%205.767812,91860.0%73.3%
63.16%194.085011,65145.5%87.5%
42.11%196.481412,42650.0%38.5%
52.63%197.067012,60022.2%80.0%
52.94%177.280411,72944.4%62.5%
64.71%171.979314,51483.3%54.5%
58.82%173.659711,85750.0%66.7%
41.18%171.260510,80127.3%66.7%
58.82%175.275513,33866.7%54.5%
75.00%167.01,01813,09971.4%77.8%
50.00%166.559410,23760.0%33.3%
43.75%163.288312,46544.4%42.9%
56.25%164.764612,30657.1%55.6%
62.50%162.172511,96570.0%50.0%
62.50%161.062112,46555.6%71.4%
53.33%156.982310,34560.0%40.0%
40.00%153.378413,07260.0%30.0%
46.67%152.372612,62350.0%44.4%
57.14%143.579310,68950.0%66.7%
76.92%131.476514,021100.0%57.1%
46.15%133.368210,59050.0%40.0%
30.77%134.371211,05037.5%20.0%
58.33%125.984112,34350.0%66.7%
25.00%121.563110,19937.5%0.0%
81.82%115.578510,67377.8%100.0%
45.45%115.175210,54662.5%0.0%
36.36%111.084114,07320.0%50.0%
54.55%111.191213,07950.0%57.1%
36.36%115.21,00113,1630.0%57.1%
63.64%111.886113,41240.0%83.3%
50.00%103.987215,64250.0%50.0%
30.00%106.372812,42833.3%28.6%
60.00%106.35818,01350.0%100.0%
30.00%106.861110,05333.3%25.0%
55.56%94.274112,10357.1%50.0%
66.67%96.880811,50283.3%33.3%
33.33%96.453410,67250.0%20.0%
50.00%87.070312,074100.0%20.0%
62.50%86.667012,41560.0%66.7%
50.00%85.983513,28933.3%60.0%
50.00%81.368913,60733.3%60.0%
37.50%81.770012,43120.0%66.7%
71.43%76.060814,36050.0%80.0%
71.43%76.587811,30975.0%66.7%
85.71%72.678812,55775.0%100.0%
42.86%76.56679,32866.7%25.0%
57.14%73.387114,37850.0%60.0%
71.43%76.663911,55760.0%100.0%
57.14%71.065711,81350.0%66.7%
42.86%71.943010,90133.3%50.0%
83.33%63.157210,921100.0%75.0%
33.33%67.36778,9940.0%100.0%
33.33%66.13589,88750.0%0.0%
80.00%56.377812,5470.0%100.0%
80.00%57.169710,03266.7%100.0%
40.00%55.778014,20850.0%33.3%

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Nasus vs Lissandra - Frequently Asked Questions

How does Nasus do against Lissandra in League of Legends?

Lissandra wins the Nasus vs Lissandra matchup with a 57.1% win rate compared to Nasus's 42.9%, a 14.3 percentage point difference. This data is based on 7 recent ranked games in patch 26.5.

How does Nasus do against Lissandra in the early game?

In the early game, Nasus has the advantage against Lissandra with a 66.7% win rate versus 33.3%. Nasus players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Nasus do against Lissandra in the late game?

In the late game, Lissandra takes over the Nasus vs Lissandra matchup with a 75.0% win rate compared to 25.0%. Lissandra scales better into team fights and objective contests after 25 minutes.

Who wins the Nasus vs Lissandra matchup?

Lissandra wins the matchup against Nasus with a 57.1% win rate in League of Legends patch 26.5. The 14.3 percentage point advantage means Lissandra is significantly favored in this lane matchup based on 7 games analyzed.

What is the best Nasus build against Lissandra?

The best Nasus build against Lissandra includes Death's Dance, Essence Reaver, Fiendhunter Bolts with Mercury's Treads. Check the matchup breakdown above for the full item path and build order.

What are the best Nasus runes against Lissandra?

The best Nasus runes against Lissandra use the Precision primary tree with Resolve secondary. This rune setup achieves a 100.0% win rate in the Nasus vs Lissandra matchup. See the full rune breakdown in the matchup comparison above.

Does Nasus counter Lissandra?

No, Nasus struggles against Lissandra with only a 42.9% win rate. Lissandra has the advantage in this matchup. Nasus players should focus on safe farming and avoiding extended trades to minimize Lissandra's lead.

How do I play Nasus against Lissandra?

When playing Nasus against Lissandra, play cautiously and avoid Lissandra's power spikes. Look for jungle assistance and team-dependent plays since Lissandra has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.