Lissandra - League of Legends Champion
Win Rate
49.1%
Pick Rate
1.1%

Lissandravs Nasus

DMage
Patch26.5
Matches469,660
LaneAll Lanes
TierAll Tiers
Last UpdatedMar 12, 2026
MethodologyData Methodology

Lissandra vs Nasus is a decisive matchup in LoL patch 26.5. Lissandra wins with a 57.1% win rate (+14.3%) over Nasus based on 7 games. Nasus wins the early laning phase while Lissandra scales better into the late game. Below you'll find the best Lissandra build, runes, laning stats, and strategies for the Lissandra vs Nasus matchup.

Lissandra Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Lissandra performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Nasus - 57.1% win rateNasus(57.1%)
Lissandra - 57.1% win rate in this matchup
Lissandra
57.1% WR
VS
Nasus vs Lissandra matchup - 42.9% win rate
Nasus
42.9% WR

Who Wins the Lissandra vs Nasus Matchup?

Lissandra wins the Lissandra vs Nasus matchup
Winner
Lissandra
Matches: 7
57.1%
Win Rate
42.9%
6.9
CS / min
6.5
1,038
DMG / min
667
9,894
Gold / game
9,328
198
Heal / min
504
564
DMG Mitigated / min
1,731
2.3
CC / min
0.7
33.3%
Early Game WR
66.7%
75.0%
Late Game WR
25.0%

Lissandra vs Nasus Matchup Summary

The Lissandra vs Nasus matchup is a decisive matchup in League of Legends ranked play. Based on 7 recent matches analyzed, Lissandra wins with a 57.1% win rate compared to Nasus's 42.9%, giving Lissandra a 14.3 percentage point advantage. Game phase dynamics play a critical role here: Nasus controls the early laning stage, but Lissandra outscales as the game goes longer. The matchup shifts dramatically depending on game length — Nasus needs to press advantages before Lissandra reaches their power spikes, while Lissandra should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Lissandra leads by 1.5s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Lissandra players can confidently pick into Nasus and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Nasus away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Lissandra vs Nasus Laning Phase Breakdown

Lissandra wins the laning phase against Nasus in League of Legends

Lissandra is favored during the laning phase against Nasus, winning 4 out of 5 key stat categories. Lissandra holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.

Farming
6.9Lissandra
6.5Nasus
Lissandra edges out Nasus by 0.4 CS per minute — a moderate farming advantage that adds up to roughly 6 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Lissandra.
Damage
1,038Lissandra
667Nasus
Lissandra heavily out-damages Nasus by 372 DMG/min, dominating both short trades and all-in fights. Nasus should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Lissandra's sustained damage advantage take over.
Economy
9,894Lissandra
9,328Nasus
Lissandra earns 566 more gold per game than Nasus, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Lissandra slightly faster item completions.
Utility
2.3Lissandra
0.7Nasus
Lissandra brings significantly more crowd control than Nasus, with 1.5 more seconds of CC per minute. This large utility gap makes Lissandra far more valuable in setting up jungle ganks, controlling objectives, and locking down targets in team fights. Nasus should invest in tenacity and position carefully to avoid being chain-CC'd.
Sustain
762Lissandra
2,235Nasus
Nasus vastly out-sustains Lissandra, healing and mitigating 1,474 more damage per minute. This massive durability gap means Nasus can absorb significant punishment and remain in lane while Lissandra is forced to recall. Building grievous wounds early is essential for Lissandra, and focusing on burst trade patterns rather than sustained fights is critical.

Best Lissandra Build Against Nasus

Sorcerer's Shoes is the optimal boots choice against Nasus, providing the mobility and stats Lissandra needs most in this matchup. The top-performing core items for Lissandra against Nasus are Luden's Echo, Liandry's Torment and Stormsurge. This combination gives Lissandra an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Nasus. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Lissandra vs Nasus matchup.

Early Game vs Late Game

Early Game
Nasus
66.7%
+33.3% advantage
Lissandra early game win rateLissandra33.3%
Nasus early game win rateNasus66.7%
Late Game
Lissandra
75.0%
+50.0% advantage
Lissandra late game win rateLissandra75.0%
Nasus late game win rateNasus25.0%

Nasus dominates the early game (first 15 minutes) with a commanding 66.7% win rate — a 33.3 percentage point lead over Lissandra. This lopsided early game means Nasus can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Lissandra is far superior in the late game (25+ minutes), boasting a 75.0% win rate — 50.0 points above Nasus. Extended games heavily favor Lissandra, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Nasus must aggressively press their early advantage and close out the game before Lissandra reaches their scaling breakpoints. If Lissandra survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Lissandra Runes Against Nasus

Sorcery rune tree - Lissandra primary runes vs NasusSorcery
Arcane Comet - best Lissandra rune vs NasusManaflow Band - best Lissandra rune vs NasusTranscendence - best Lissandra rune vs NasusScorch - best Lissandra rune vs Nasus
Precision rune tree - Lissandra secondary runes vs NasusPrecision
Legend: Haste - best Lissandra rune vs NasusPresence of Mind - best Lissandra rune vs Nasus
100.0% WR

Running Sorcery primary with Precision secondary allows Lissandra to press their advantage against Nasus, amplifying the strengths that make this a favorable matchup.


Lissandra matchup data for League of Legends patch 26.5. The table below shows Lissandra's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Lissandra build, runes, laning stats, and early vs late game analysis for that specific matchup.

Lissandra matchup win rates and stats in League of Legends patch 26.5
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
42.86%706.885711,86856.3%31.6%
40.58%696.979111,62050.0%30.3%
53.66%416.896612,21547.6%60.0%
50.00%386.793211,89258.8%42.9%
51.35%376.580812,68863.6%46.1%
41.18%346.879211,04542.1%40.0%
51.61%316.688311,00653.9%50.0%
58.62%296.979012,22260.0%57.9%
44.83%296.575111,17938.5%50.0%
48.15%276.879112,62550.0%46.7%
37.04%276.069210,53533.3%40.0%
44.44%276.964611,07850.0%38.5%
70.37%277.083711,76061.5%78.6%
42.31%266.673112,05944.4%41.2%
54.55%226.769712,87657.1%53.3%
59.09%226.982211,70954.5%63.6%
50.00%206.766710,63960.0%40.0%
40.00%206.964510,35036.4%44.4%
42.11%196.985210,37845.5%37.5%
38.89%186.275411,03155.6%22.2%
64.71%176.77139,58272.7%50.0%
58.82%176.378210,93242.9%70.0%
50.00%166.367310,46157.1%44.4%
60.00%156.880911,56266.7%50.0%
40.00%156.666210,34850.0%28.6%
38.46%136.574511,30628.6%50.0%
38.46%136.984613,62350.0%33.3%
41.67%126.81,03413,32050.0%37.5%
50.00%127.281612,49040.0%57.1%
81.82%116.37409,89271.4%100.0%
54.55%117.399013,91325.0%71.4%
36.36%116.672912,5330.0%40.0%
70.00%106.287111,63366.7%75.0%
50.00%106.776712,08920.0%80.0%
40.00%104.66679,70950.0%25.0%
70.00%106.876911,46725.0%100.0%
55.56%95.057810,34966.7%33.3%
77.78%97.073711,87650.0%100.0%
75.00%87.383310,14885.7%0.0%
0.00%83.765811,3520.0%0.0%
57.14%76.91,0389,89433.3%75.0%
57.14%77.084912,82533.3%75.0%
33.33%64.565010,1650.0%66.7%
66.67%67.179213,087100.0%50.0%
50.00%66.464510,87666.7%33.3%
33.33%67.16289,92950.0%0.0%
50.00%67.694512,19650.0%50.0%
83.33%66.888014,681100.0%80.0%
40.00%57.678012,61533.3%50.0%
40.00%56.283111,5370.0%50.0%
40.00%55.878811,14133.3%50.0%
40.00%52.368210,56933.3%50.0%
40.00%56.91,01515,1400.0%66.7%
60.00%55.278810,260100.0%0.0%
60.00%57.41,06212,19450.0%66.7%

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Lissandra vs Nasus - Frequently Asked Questions

How does Lissandra do against Nasus in League of Legends?

Lissandra wins the Lissandra vs Nasus matchup with a 57.1% win rate compared to Nasus's 42.9%, a 14.3 percentage point difference. This data is based on 7 recent ranked games in patch 26.5.

How does Lissandra do against Nasus in the early game?

In the early game, Nasus has the advantage against Lissandra with a 66.7% win rate versus 33.3%. Nasus players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Lissandra do against Nasus in the late game?

In the late game, Lissandra takes over the Lissandra vs Nasus matchup with a 75.0% win rate compared to 25.0%. Lissandra scales better into team fights and objective contests after 25 minutes.

Who wins the Lissandra vs Nasus matchup?

Lissandra wins the matchup against Nasus with a 57.1% win rate in League of Legends patch 26.5. The 14.3 percentage point advantage means Lissandra is significantly favored in this lane matchup based on 7 games analyzed.

What is the best Lissandra build against Nasus?

The best Lissandra build against Nasus includes Luden's Echo, Liandry's Torment, Stormsurge with Sorcerer's Shoes. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Lissandra runes against Nasus?

The best Lissandra runes against Nasus use the Sorcery primary tree with Precision secondary. This rune setup achieves a 100.0% win rate in the Lissandra vs Nasus matchup. See the full rune breakdown in the matchup comparison above.

Does Lissandra counter Nasus?

Yes, Lissandra has a favorable matchup against Nasus with a 57.1% win rate. Lissandra strongly counters Nasus in lane based on current patch 26.5 data.

How do I play Lissandra against Nasus?

When playing Lissandra against Nasus, leverage your statistical advantages by trading aggressively during favorable windows. Play safe early and scale into your power spikes where you outperform Nasus. Build the recommended items and runes for this specific matchup for the best results.