Lissandra - League of Legends Champion
Win Rate
51.3%
Pick Rate
2.2%

Lissandravs Nasus

AMage
Patch26.7
Matches949,984
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 27, 2026
MethodologyData Methodology

Lissandra vs Nasus is a decisive matchup in LoL patch 26.7. Lissandra wins with a 55.6% win rate (+11.1%) over Nasus based on 9 games. Lissandra wins the early laning phase while Nasus scales better into the late game. Below you'll find the best Lissandra build, runes, laning stats, and strategies for the Lissandra vs Nasus matchup.

Lissandra Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Lissandra performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Nasus - 55.6% win rateNasus(55.6%)
Lissandra - 55.6% win rate in this matchup
Lissandra
55.6% WR
VS
Nasus vs Lissandra matchup - 44.4% win rate
Nasus
44.4% WR

Who Wins the Lissandra vs Nasus Matchup?

Lissandra wins the Lissandra vs Nasus matchup
Winner
Lissandra
Matches: 9
55.6%
Win Rate
44.4%
7.2
CS / min
6.8
882
DMG / min
681
11,467
Gold / game
11,828
137
Heal / min
520
395
DMG Mitigated / min
1,334
1.9
CC / min
0.6
75.0%
Early Game WR
25.0%
40.0%
Late Game WR
60.0%

Lissandra vs Nasus Matchup Summary

The Lissandra vs Nasus matchup is a decisive matchup in League of Legends ranked play. Based on 9 recent matches analyzed, Lissandra wins with a 55.6% win rate compared to Nasus's 44.4%, giving Lissandra a 11.1 percentage point advantage. Game phase dynamics play a critical role here: Lissandra controls the early laning stage, but Nasus outscales as the game goes longer. The matchup shifts dramatically depending on game length — Lissandra needs to press advantages before Nasus reaches their power spikes, while Nasus should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in sustain, where Nasus leads by 1,322 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Lissandra players can confidently pick into Nasus and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Nasus away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Lissandra vs Nasus Laning Phase Breakdown

Lissandra wins the laning phase against Nasus in League of Legends

Lissandra is favored during the laning phase against Nasus, winning 3 out of 5 key stat categories. Lissandra holds advantages in farming, damage and crowd control, making them the stronger laner in this matchup.

Farming
7.2Lissandra
6.8Nasus
Lissandra edges out Nasus by 0.4 CS per minute — a moderate farming advantage that adds up to roughly 6 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Lissandra.
Damage
882Lissandra
681Nasus
Lissandra heavily out-damages Nasus by 202 DMG/min, dominating both short trades and all-in fights. Nasus should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Lissandra's sustained damage advantage take over.
Economy
11,467Lissandra
11,828Nasus
Nasus earns 361 more gold per game than Lissandra, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Nasus slightly faster item completions.
Utility
1.9Lissandra
0.6Nasus
Lissandra brings significantly more crowd control than Nasus, with 1.3 more seconds of CC per minute. This large utility gap makes Lissandra far more valuable in setting up jungle ganks, controlling objectives, and locking down targets in team fights. Nasus should invest in tenacity and position carefully to avoid being chain-CC'd.
Sustain
532Lissandra
1,854Nasus
Nasus vastly out-sustains Lissandra, healing and mitigating 1,322 more damage per minute. This massive durability gap means Nasus can absorb significant punishment and remain in lane while Lissandra is forced to recall. Building grievous wounds early is essential for Lissandra, and focusing on burst trade patterns rather than sustained fights is critical.

Best Lissandra Build Against Nasus

Spellslinger's Shoes is the optimal boots choice against Nasus, providing the mobility and stats Lissandra needs most in this matchup. The top-performing core items for Lissandra against Nasus are Shadowflame, Zhonya's Hourglass and Malignance. This combination gives Lissandra an effective balance of damage, survivability, and utility for the matchup. This build has a 33.3% win rate across 3 games. While the overall matchup may be difficult, this item path gives Lissandra the best chance to compete against Nasus. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Lissandra vs Nasus matchup.

Early Game vs Late Game

Early Game
Lissandra
75.0%
+50.0% advantage
Lissandra early game win rateLissandra75.0%
Nasus early game win rateNasus25.0%
Late Game
Nasus
60.0%
+20.0% advantage
Lissandra late game win rateLissandra40.0%
Nasus late game win rateNasus60.0%

Lissandra dominates the early game (first 15 minutes) with a commanding 75.0% win rate — a 50.0 percentage point lead over Nasus. This lopsided early game means Lissandra can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Nasus is far superior in the late game (25+ minutes), boasting a 60.0% win rate — 20.0 points above Lissandra. Extended games heavily favor Nasus, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Lissandra must aggressively press their early advantage and close out the game before Nasus reaches their scaling breakpoints. If Nasus survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Lissandra Runes Against Nasus

Precision rune tree - Lissandra primary runes vs NasusPrecision
Lethal Tempo - best Lissandra rune vs NasusTriumph - best Lissandra rune vs NasusLegend: Haste - best Lissandra rune vs NasusLast Stand - best Lissandra rune vs Nasus
Resolve rune tree - Lissandra secondary runes vs NasusResolve
Second Wind - best Lissandra rune vs NasusOvergrowth - best Lissandra rune vs Nasus
100.0% WR

Running Precision primary with Resolve secondary allows Lissandra to press their advantage against Nasus, amplifying the strengths that make this a favorable matchup.


Lissandra matchup data for League of Legends patch 26.7. The table below shows Lissandra's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Lissandra build, runes, laning stats, and early vs late game analysis for that specific matchup.

Lissandra matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
60.00%1306.883712,37853.6%64.9%
57.52%1136.882011,83565.2%52.2%
50.00%766.890711,85747.2%52.5%
45.95%746.778211,93537.5%52.4%
47.95%736.982512,39648.3%47.7%
52.11%717.081212,61135.7%62.8%
53.62%696.788911,32658.1%50.0%
54.55%666.798912,99555.2%54.0%
50.00%626.990112,04736.7%62.5%
54.10%616.687711,06545.5%64.3%
57.38%616.276711,40053.6%60.6%
34.48%586.766810,83031.4%39.1%
40.00%556.372811,33333.3%45.2%
46.94%496.975711,65340.0%51.7%
50.00%486.776511,97850.0%50.0%
50.00%406.476411,31941.2%56.5%
65.00%407.283311,56863.6%66.7%
56.41%397.084511,79244.4%66.7%
60.00%356.876110,99150.0%70.6%
48.57%356.881511,55440.0%55.0%
36.36%336.784111,39846.7%27.8%
21.21%336.478711,43923.1%20.0%
63.33%307.380811,58476.5%46.1%
62.07%297.188313,06883.3%47.1%
58.62%296.596211,72763.6%55.6%
53.57%286.983410,91262.5%41.7%
46.43%286.68679,78147.1%45.5%
53.57%286.881411,53950.0%56.3%
59.26%277.079712,15157.1%61.5%
69.23%266.586913,22971.4%68.4%
57.69%266.679612,06775.0%42.9%
40.00%257.276711,82854.5%28.6%
64.00%256.680511,12450.0%73.3%
41.67%246.992712,63340.0%42.9%
66.67%247.178811,24454.5%76.9%
73.68%197.196712,77550.0%90.9%
44.44%187.31,06512,47460.0%25.0%
64.71%177.290311,48980.0%42.9%
33.33%156.473710,70622.2%50.0%
57.14%146.289412,26342.9%71.4%
42.86%147.375110,43150.0%25.0%
76.92%136.783113,11175.0%77.8%
38.46%136.082212,47860.0%25.0%
30.77%136.896711,40720.0%37.5%
15.38%136.584811,09216.7%14.3%
45.45%116.480812,11440.0%50.0%
27.27%116.792811,21620.0%33.3%
54.55%116.888611,95450.0%57.1%
40.00%106.882512,83166.7%28.6%
50.00%106.452910,44128.6%100.0%
55.56%96.295114,28150.0%57.1%
88.89%97.280612,70675.0%100.0%
55.56%97.288211,46775.0%40.0%
55.56%95.672312,03950.0%60.0%
55.56%97.786112,78766.7%50.0%
75.00%87.487510,71080.0%66.7%
57.14%77.387510,78575.0%33.3%
42.86%75.873510,32566.7%25.0%
85.71%77.087111,26283.3%100.0%
71.43%76.173511,33280.0%50.0%
50.00%61.761410,6240.0%60.0%
83.33%67.91,14313,99850.0%100.0%
33.33%67.796512,2420.0%66.7%
33.33%66.686711,32825.0%50.0%
50.00%62.45439,94466.7%33.3%
83.33%67.183312,020100.0%80.0%
16.67%67.26078,27816.7%0.0%
60.00%56.01,16411,19766.7%50.0%
40.00%53.07276,78640.0%0.0%
20.00%57.793410,62525.0%0.0%
20.00%55.05978,21425.0%0.0%
40.00%53.45178,76125.0%100.0%
80.00%55.064712,91850.0%100.0%
40.00%56.783411,7270.0%66.7%
60.00%56.077611,837100.0%33.3%
40.00%56.374111,1560.0%50.0%
60.00%56.897912,10050.0%66.7%
80.00%56.51,08510,600100.0%66.7%

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Lissandra vs Nasus - Frequently Asked Questions

How does Lissandra do against Nasus in League of Legends?

Lissandra wins the Lissandra vs Nasus matchup with a 55.6% win rate compared to Nasus's 44.4%, a 11.1 percentage point difference. This data is based on 9 recent ranked games in patch 26.7.

How does Lissandra do against Nasus in the early game?

In the early game, Lissandra has the advantage against Nasus with a 75.0% win rate versus 25.0%. Lissandra players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Lissandra do against Nasus in the late game?

In the late game, Nasus takes over the Lissandra vs Nasus matchup with a 60.0% win rate compared to 40.0%. Nasus scales better into team fights and objective contests after 25 minutes.

Who wins the Lissandra vs Nasus matchup?

Lissandra wins the matchup against Nasus with a 55.6% win rate in League of Legends patch 26.7. The 11.1 percentage point advantage means Lissandra is significantly favored in this lane matchup based on 9 games analyzed.

What is the best Lissandra build against Nasus?

The best Lissandra build against Nasus includes Shadowflame, Zhonya's Hourglass, Malignance with Spellslinger's Shoes. This build achieves a 33.3% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Lissandra runes against Nasus?

The best Lissandra runes against Nasus use the Precision primary tree with Resolve secondary. This rune setup achieves a 100.0% win rate in the Lissandra vs Nasus matchup. See the full rune breakdown in the matchup comparison above.

Does Lissandra counter Nasus?

Yes, Lissandra has a favorable matchup against Nasus with a 55.6% win rate. Lissandra strongly counters Nasus in lane based on current patch 26.7 data.

How do I play Lissandra against Nasus?

When playing Lissandra against Nasus, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.