Nidalee - League of Legends Champion
Win Rate
48.4%
Pick Rate
0.7%

Nidaleevs Karthus

FAssassinMage
Patch26.9
Matches514,344
LaneAll Lanes
TierAll Tiers
Last UpdatedMay 10, 2026
MethodologyData Methodology

Nidalee vs Karthus is a decisive matchup in LoL patch 26.9. Karthus wins with a 71.4% win rate (+42.9%) over Nidalee based on 7 games. Karthus wins the early laning phase while Nidalee scales better into the late game. Below you'll find the best Nidalee build, runes, laning stats, and strategies for the Nidalee vs Karthus matchup.

Nidalee Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Nidalee performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Karthus - 28.6% win rateKarthus(28.6%)
Nidalee - 28.6% win rate in this matchup
Nidalee
28.6% WR
VS
Karthus vs Nidalee matchup - 71.4% win rate
Karthus
71.4% WR

Who Wins the Nidalee vs Karthus Matchup?

Karthus wins the Nidalee vs Karthus matchup
Winner
Karthus
Matches: 7
28.6%
Win Rate
71.4%
0.9
CS / min
1.7
766
DMG / min
1,248
9,421
Gold / game
9,768
711
Heal / min
276
574
DMG Mitigated / min
449
0.2
CC / min
0.8
0.0%
Early Game WR
100.0%
50.0%
Late Game WR
50.0%

Nidalee vs Karthus Matchup Summary

The Nidalee vs Karthus matchup is a decisive matchup in League of Legends ranked play. Based on 7 recent matches analyzed, Karthus wins with a 71.4% win rate compared to Nidalee's 28.6%, giving Karthus a 42.9 percentage point advantage. Game phase dynamics play a critical role here: Karthus controls the early laning stage, but Nidalee outscales as the game goes longer. The matchup shifts dramatically depending on game length — Karthus needs to press advantages before Nidalee reaches their power spikes, while Nidalee should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Karthus leads by 0.5s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Karthus has a strong advantage in this matchup. Nidalee players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Karthus overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Nidalee vs Karthus Laning Phase Breakdown

Karthus wins the laning phase against Nidalee in League of Legends

Karthus is favored during the laning phase against Nidalee, winning 4 out of 5 key stat categories. Karthus holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.

Farming
0.9Nidalee
1.7Karthus
Karthus significantly out-farms Nidalee by 0.8 CS per minute, accumulating an estimated 12 CS lead by mid game. This substantial farming gap gives Karthus a major gold advantage and earlier item completions. Nidalee players should prioritize wave management techniques like freezing near tower and using abilities efficiently to minimize the deficit.
Damage
766Nidalee
1,248Karthus
Karthus heavily out-damages Nidalee by 482 DMG/min, dominating both short trades and all-in fights. Nidalee should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Karthus's sustained damage advantage take over.
Economy
9,421Nidalee
9,768Karthus
Karthus earns 347 more gold per game than Nidalee, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Karthus slightly faster item completions.
Utility
0.2Nidalee
0.8Karthus
Karthus provides 0.5 seconds more crowd control per minute than Nidalee, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Karthus coordinate with their jungler and control the pace of skirmishes.
Sustain
1,285Nidalee
725Karthus
Nidalee vastly out-sustains Karthus, healing and mitigating 560 more damage per minute. This massive durability gap means Nidalee can absorb significant punishment and remain in lane while Karthus is forced to recall. Building grievous wounds early is essential for Karthus, and focusing on burst trade patterns rather than sustained fights is critical.

Best Nidalee Build Against Karthus

Sorcerer's Shoes is the optimal boots choice against Karthus, providing the mobility and stats Nidalee needs most in this matchup. The top-performing core items for Nidalee against Karthus are Stormsurge, Shadowflame and Lich Bane. This combination gives Nidalee an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Nidalee vs Karthus matchup.

Early Game vs Late Game

Early Game
Karthus
100.0%
+100.0% advantage
Nidalee early game win rateNidalee0.0%
Karthus early game win rateKarthus100.0%
Late Game
Nidalee
50.0%
+0.0% advantage
Nidalee late game win rateNidalee50.0%
Karthus late game win rateKarthus50.0%

Karthus dominates the early game (first 15 minutes) with a commanding 100.0% win rate — a 100.0 percentage point lead over Nidalee. This lopsided early game means Karthus can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Late game (25+ minutes) is equally balanced, with Nidalee at 50.0% win rate — only 0.0 points ahead of Karthus. Team fight execution and macro play determine the winner at this stage, not champion matchup advantage.

The power dynamics shift as the game progresses — Karthus has the edge early, but Nidalee gradually takes over. However, the margins are slim enough that either champion can win at any stage with the right plays. Focus on taking advantages when you have them rather than waiting for a specific game phase.

Best Nidalee Runes Against Karthus

Domination rune tree - Nidalee primary runes vs KarthusDomination
Dark Harvest - best Nidalee rune vs KarthusSudden Impact - best Nidalee rune vs KarthusGrisly Mementos - best Nidalee rune vs KarthusTreasure Hunter - best Nidalee rune vs Karthus
Sorcery rune tree - Nidalee secondary runes vs KarthusSorcery
Transcendence - best Nidalee rune vs KarthusWaterwalking - best Nidalee rune vs Karthus
66.7% WR

The Domination and Sorcery rune setup gives Nidalee the best tools to compete against Karthus in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Nidalee matchup data for League of Legends patch 26.9. The table below shows Nidalee's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Nidalee build, runes, laning stats, and early vs late game analysis for that specific matchup.

Nidalee matchup win rates and stats in League of Legends patch 26.9
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
58.14%430.868912,17752.4%63.6%
40.00%250.862712,32345.5%35.7%
58.33%240.876713,67462.5%56.3%
28.57%211.263912,20537.5%23.1%
42.86%211.076713,15644.4%41.7%
26.32%191.073613,76633.3%23.1%
44.44%180.874213,14442.9%45.5%
52.94%171.65009,66637.5%66.7%
23.53%171.366012,34533.3%18.2%
41.18%170.973611,61140.0%42.9%
50.00%160.788313,02133.3%60.0%
43.75%160.757410,27355.6%28.6%
60.00%150.872311,70675.0%42.9%
53.33%150.882512,23560.0%40.0%
71.43%140.971912,62657.1%85.7%
23.08%131.377912,36320.0%25.0%
63.64%110.981614,82966.7%62.5%
45.45%110.869612,47650.0%40.0%
63.64%111.46459,816100.0%50.0%
60.00%100.970510,56857.1%66.7%
20.00%101.862311,29020.0%20.0%
22.22%91.085313,31325.0%20.0%
55.56%91.45738,77975.0%40.0%
77.78%91.655412,22180.0%75.0%
55.56%91.16329,63825.0%80.0%
66.67%92.25859,22150.0%80.0%
55.56%90.753412,605100.0%33.3%
66.67%93.864910,16050.0%80.0%
44.44%91.068611,28020.0%75.0%
25.00%81.167711,76225.0%25.0%
75.00%81.373212,22880.0%66.7%
50.00%80.85699,92240.0%66.7%
37.50%80.757711,47633.3%40.0%
62.50%81.597715,61650.0%66.7%
37.50%81.071012,28166.7%20.0%
71.43%71.776312,20050.0%100.0%
28.57%70.765411,97833.3%25.0%
14.29%70.971711,5360.0%33.3%
71.43%71.44908,133100.0%33.3%
57.14%71.072914,15133.3%75.0%
100.00%71.462011,114100.0%100.0%
28.57%70.97669,4210.0%50.0%
42.86%71.45729,43640.0%50.0%
33.33%61.084615,0400.0%40.0%
16.67%61.46429,02633.3%0.0%
66.67%60.773713,6490.0%80.0%
100.00%60.86528,950100.0%100.0%
100.00%60.992411,762100.0%100.0%
50.00%61.573512,3090.0%60.0%
33.33%61.34846,80633.3%0.0%
83.33%60.91,07316,261100.0%80.0%
60.00%50.67758,54075.0%0.0%
20.00%51.14068,96050.0%0.0%
80.00%51.272411,02250.0%100.0%
0.00%50.956211,8600.0%0.0%
40.00%51.351010,59950.0%33.3%
40.00%53.282412,32050.0%33.3%
40.00%51.45939,53766.7%0.0%
80.00%50.859712,55866.7%100.0%

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Nidalee vs Karthus - Frequently Asked Questions

How does Nidalee do against Karthus in League of Legends?

Karthus wins the Nidalee vs Karthus matchup with a 71.4% win rate compared to Nidalee's 28.6%, a 42.9 percentage point difference. This data is based on 7 recent ranked games in patch 26.9.

How does Nidalee do against Karthus in the early game?

In the early game, Karthus has the advantage against Nidalee with a 100.0% win rate versus 0.0%. Karthus players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Nidalee do against Karthus in the late game?

In the late game, Nidalee takes over the Nidalee vs Karthus matchup with a 50.0% win rate compared to 50.0%. Nidalee scales better into team fights and objective contests after 25 minutes.

Who wins the Nidalee vs Karthus matchup?

Karthus wins the matchup against Nidalee with a 71.4% win rate in League of Legends patch 26.9. The 42.9 percentage point advantage means Karthus is significantly favored in this lane matchup based on 7 games analyzed.

What is the best Nidalee build against Karthus?

The best Nidalee build against Karthus includes Stormsurge, Shadowflame, Lich Bane with Sorcerer's Shoes. Check the matchup breakdown above for the full item path and build order.

What are the best Nidalee runes against Karthus?

The best Nidalee runes against Karthus use the Domination primary tree with Sorcery secondary. This rune setup achieves a 66.7% win rate in the Nidalee vs Karthus matchup. See the full rune breakdown in the matchup comparison above.

Does Nidalee counter Karthus?

No, Nidalee struggles against Karthus with only a 28.6% win rate. Karthus has the advantage in this matchup. Nidalee players should focus on safe farming and avoiding extended trades to minimize Karthus's lead.

How do I play Nidalee against Karthus?

When playing Nidalee against Karthus, play cautiously and avoid Karthus's power spikes. Focus on safe farming — you outscale Karthus in the late game. Use the matchup-specific build and runes above to optimize your chances.