Sylas - League of Legends Champion
Win Rate
49.9%
Pick Rate
4.3%

Sylasvs Karthus

CMageAssassin
Patch26.7
Matches949,984
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 20, 2026
MethodologyData Methodology

Sylas vs Karthus is a decisive matchup in LoL patch 26.7. Karthus wins with a 83.3% win rate (+66.7%) over Sylas based on 12 games. Karthus holds the advantage in both the early and late game. Below you'll find the best Sylas build, runes, laning stats, and strategies for the Sylas vs Karthus matchup.

Sylas Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Sylas performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Karthus - 16.7% win rateKarthus(16.7%)
Sylas - 16.7% win rate in this matchup
Sylas
16.7% WR
VS
Karthus vs Sylas matchup - 83.3% win rate
Karthus
83.3% WR

Who Wins the Sylas vs Karthus Matchup?

Karthus wins the Sylas vs Karthus matchup
Winner
Karthus
Matches: 12
16.7%
Win Rate
83.3%
0.9
CS / min
1.4
665
DMG / min
1,238
12,249
Gold / game
15,117
435
Heal / min
358
789
DMG Mitigated / min
503
0.7
CC / min
0.6
33.3%
Early Game WR
66.7%
11.1%
Late Game WR
88.9%

Sylas vs Karthus Matchup Summary

The Sylas vs Karthus matchup is a decisive matchup in League of Legends ranked play. Based on 12 recent matches analyzed, Karthus wins with a 83.3% win rate compared to Sylas's 16.7%, giving Karthus a 66.7 percentage point advantage. Karthus dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Sylas players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in damage output, where Karthus leads by 572 DMG/min — a difference that heavily influences the outcome of trades and skirmishes. Karthus has a strong advantage in this matchup. Sylas players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Karthus overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Sylas vs Karthus Laning Phase Breakdown

Karthus wins the laning phase against Sylas in League of Legends

Karthus is favored during the laning phase against Sylas, winning 3 out of 5 key stat categories. Karthus holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.

Farming
0.9Sylas
1.4Karthus
Karthus edges out Sylas by 0.5 CS per minute — a moderate farming advantage that adds up to roughly 8 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Karthus.
Damage
665Sylas
1,238Karthus
Karthus heavily out-damages Sylas by 572 DMG/min, dominating both short trades and all-in fights. Sylas should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Karthus's sustained damage advantage take over.
Economy
12,249Sylas
15,117Karthus
Karthus generates a commanding 2,868 more gold per game than Sylas. This substantial economic advantage means Karthus consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Sylas should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.7Sylas
0.6Karthus
Both Sylas and Karthus provide similar amounts of crowd control (0.1s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
1,225Sylas
861Karthus
Sylas vastly out-sustains Karthus, healing and mitigating 364 more damage per minute. This massive durability gap means Sylas can absorb significant punishment and remain in lane while Karthus is forced to recall. Building grievous wounds early is essential for Karthus, and focusing on burst trade patterns rather than sustained fights is critical.

Best Sylas Build Against Karthus

Sorcerer's Shoes is the optimal boots choice against Karthus, providing the mobility and stats Sylas needs most in this matchup. The top-performing core items for Sylas against Karthus are Riftmaker, Zhonya's Hourglass and Hextech Rocketbelt. This combination gives Sylas an effective balance of damage, survivability, and utility for the matchup. This build has a 33.3% win rate across 3 games. While the overall matchup may be difficult, this item path gives Sylas the best chance to compete against Karthus. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Sylas vs Karthus matchup.

Early Game vs Late Game

Early Game
Karthus
66.7%
+33.3% advantage
Sylas early game win rateSylas33.3%
Karthus early game win rateKarthus66.7%
Late Game
Karthus
88.9%
+77.8% advantage
Sylas late game win rateSylas11.1%
Karthus late game win rateKarthus88.9%

Karthus dominates the early game (first 15 minutes) with a commanding 66.7% win rate — a 33.3 percentage point lead over Sylas. This lopsided early game means Karthus can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Karthus is far superior in the late game (25+ minutes), boasting a 88.9% win rate — 77.8 points above Sylas. Extended games heavily favor Karthus, whose kit and scaling make them a dominant force in team fights and objective control.

Karthus holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Sylas players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Sylas Runes Against Karthus

Precision rune tree - Sylas primary runes vs KarthusPrecision
Conqueror - best Sylas rune vs KarthusTriumph - best Sylas rune vs KarthusLegend: Haste - best Sylas rune vs KarthusLast Stand - best Sylas rune vs Karthus
Inspiration rune tree - Sylas secondary runes vs KarthusInspiration
Cosmic Insight - best Sylas rune vs KarthusMagical Footwear - best Sylas rune vs Karthus
28.6% WR

The Precision and Inspiration rune setup gives Sylas the best tools to compete against Karthus in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Sylas matchup data for League of Legends patch 26.7. The table below shows Sylas's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Sylas build, runes, laning stats, and early vs late game analysis for that specific matchup.

Sylas matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
51.14%1765.483411,10953.8%48.2%
52.74%1461.080912,90950.0%54.9%
45.28%1065.581811,27548.0%42.9%
54.81%1044.388011,96258.3%51.8%
54.64%975.290311,82161.1%50.8%
51.69%895.595411,52555.8%47.8%
52.33%864.785210,93352.0%52.8%
49.41%855.478310,70254.5%43.9%
55.70%795.585210,93453.5%58.3%
54.43%793.592412,33254.0%54.8%
52.00%753.679011,13448.8%56.3%
47.95%734.972211,16441.7%54.0%
51.47%685.279111,41360.6%42.9%
35.29%681.071312,95244.4%29.3%
37.31%675.180310,03243.3%32.4%
50.75%675.485511,30847.1%54.5%
47.76%670.974512,12552.6%41.4%
53.73%674.575810,63256.7%51.4%
45.90%615.688410,75554.5%35.7%
54.39%574.379210,81761.1%42.9%
50.00%561.363812,18243.5%54.5%
47.27%550.978812,98947.8%46.9%
49.09%550.971412,34356.7%40.0%
50.00%545.473710,71061.5%39.3%
33.96%535.179411,73631.6%35.3%
40.38%523.373511,30946.1%34.6%
38.46%521.164311,78838.5%38.5%
39.58%485.783910,99634.6%45.5%
29.17%481.468011,16123.8%33.3%
60.87%460.984312,89868.2%54.2%
51.11%455.593511,35655.0%48.0%
52.38%425.488411,76868.4%39.1%
56.10%415.586910,96355.0%57.1%
58.54%411.390212,85766.7%52.2%
43.90%415.580712,15953.3%38.5%
48.72%393.282712,33250.0%47.6%
56.41%395.585011,89466.7%44.4%
55.56%365.399311,52644.4%66.7%
52.78%365.794811,44565.2%30.8%
38.89%364.169110,02443.8%35.0%
48.57%351.180113,57147.1%50.0%
48.57%355.386011,02537.5%57.9%
47.06%342.273912,72750.0%44.4%
57.58%331.075212,59350.0%64.7%
48.48%331.576011,33545.8%55.6%
51.52%332.270212,12160.0%44.4%
50.00%325.771510,27247.4%53.9%
48.39%312.997712,46437.5%60.0%
70.00%301.175012,70883.3%61.1%
50.00%283.67519,83466.7%37.5%
42.86%285.477411,94627.3%52.9%
35.71%284.984511,66016.7%50.0%
42.86%281.083212,20041.2%45.5%
46.43%283.480611,96753.3%38.5%
55.56%271.783912,48769.2%42.9%
34.62%261.577212,55521.4%50.0%
64.00%255.389711,86164.3%63.6%
56.00%251.485813,13563.6%50.0%
62.50%241.674513,25362.5%62.5%
37.50%241.369211,41960.0%21.4%
54.17%240.966912,53850.0%60.0%
43.48%233.076112,57066.7%28.6%
52.17%231.164112,19355.6%50.0%
36.36%225.879210,48641.7%30.0%
27.27%223.277110,51633.3%20.0%
50.00%225.185211,72733.3%61.5%
54.55%225.580412,18450.0%57.1%
71.43%211.191814,81485.7%64.3%
33.33%216.088610,66645.5%20.0%
45.00%201.570810,23542.9%50.0%
50.00%205.57679,63150.0%50.0%
55.00%200.885413,47062.5%50.0%
36.84%194.576810,23936.4%37.5%
55.56%181.278312,09450.0%62.5%
38.89%184.71,01911,06722.2%55.6%
61.11%183.675812,53980.0%37.5%
50.00%182.171911,70133.3%58.3%
61.11%181.679410,10237.5%80.0%
29.41%175.292311,28133.3%27.3%
35.29%172.881812,05528.6%40.0%
50.00%166.28849,40658.3%25.0%
68.75%160.878514,49160.0%72.7%
26.67%153.088511,78622.2%33.3%
66.67%154.684413,33033.3%75.0%
33.33%153.779012,27520.0%40.0%
46.67%151.579612,47328.6%62.5%
46.67%152.56648,78841.7%66.7%
57.14%140.792813,55250.0%66.7%
50.00%145.393412,22442.9%57.1%
61.54%132.576310,32355.6%75.0%
61.54%133.379112,08250.0%66.7%
16.67%120.966512,24933.3%11.1%
50.00%122.084411,76862.5%25.0%
75.00%120.873210,58566.7%83.3%
27.27%111.06169,06728.6%25.0%
36.36%111.282513,61025.0%42.9%
45.45%115.593910,98150.0%40.0%
36.36%112.769910,05842.9%25.0%
63.64%116.388911,07060.0%66.7%
72.73%114.91,00712,98766.7%75.0%
40.00%104.881511,22340.0%40.0%
50.00%103.874411,25066.7%25.0%
40.00%102.074810,02950.0%33.3%
30.00%101.65808,83440.0%20.0%
60.00%105.71,01513,13460.0%60.0%
50.00%101.165810,84050.0%50.0%
60.00%101.876212,13940.0%80.0%
50.00%101.483610,33666.7%25.0%
70.00%105.195914,311100.0%66.7%
44.44%91.064711,76650.0%42.9%
44.44%91.686113,63140.0%50.0%
22.22%95.36869,6640.0%40.0%
55.56%94.983813,42166.7%50.0%
55.56%95.36708,46275.0%40.0%
66.67%91.76489,956100.0%40.0%
55.56%90.788513,04960.0%50.0%
44.44%91.65108,12740.0%50.0%
50.00%82.789510,07750.0%50.0%
62.50%80.872912,64850.0%75.0%
62.50%85.489011,01150.0%75.0%
0.00%71.25468,0770.0%0.0%
14.29%74.97138,92233.3%0.0%
85.71%70.762512,978100.0%83.3%
14.29%72.766510,2350.0%16.7%
42.86%74.569011,07925.0%66.7%
42.86%71.87218,79550.0%33.3%
50.00%63.176012,1080.0%60.0%
16.67%62.567511,4270.0%25.0%
50.00%62.04797,27050.0%0.0%
66.67%65.31,11414,14133.3%100.0%
33.33%65.279610,45520.0%100.0%
66.67%64.997711,508100.0%33.3%
50.00%62.25969,71166.7%33.3%
33.33%65.779210,68350.0%0.0%
20.00%55.870811,10833.3%0.0%
60.00%56.58499,84375.0%0.0%
40.00%50.879011,39750.0%33.3%
80.00%55.91,17813,12350.0%100.0%
60.00%51.36117,02133.3%100.0%
80.00%54.072810,831100.0%66.7%
40.00%54.692314,2730.0%50.0%
20.00%51.96638,52133.3%0.0%
20.00%54.675914,9090.0%20.0%
0.00%55.685212,4910.0%0.0%

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Sylas vs Karthus - Frequently Asked Questions

How does Sylas do against Karthus in League of Legends?

Karthus wins the Sylas vs Karthus matchup with a 83.3% win rate compared to Sylas's 16.7%, a 66.7 percentage point difference. This data is based on 12 recent ranked games in patch 26.7.

How does Sylas do against Karthus in the early game?

In the early game, Karthus has the advantage against Sylas with a 66.7% win rate versus 33.3%. Karthus players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Sylas do against Karthus in the late game?

In the late game, Karthus takes over the Sylas vs Karthus matchup with a 88.9% win rate compared to 11.1%. Karthus scales better into team fights and objective contests after 25 minutes.

Who wins the Sylas vs Karthus matchup?

Karthus wins the matchup against Sylas with a 83.3% win rate in League of Legends patch 26.7. The 66.7 percentage point advantage means Karthus is significantly favored in this lane matchup based on 12 games analyzed.

What is the best Sylas build against Karthus?

The best Sylas build against Karthus includes Riftmaker, Zhonya's Hourglass, Hextech Rocketbelt with Sorcerer's Shoes. This build achieves a 33.3% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Sylas runes against Karthus?

The best Sylas runes against Karthus use the Precision primary tree with Inspiration secondary. This rune setup achieves a 28.6% win rate in the Sylas vs Karthus matchup. See the full rune breakdown in the matchup comparison above.

Does Sylas counter Karthus?

No, Sylas struggles against Karthus with only a 16.7% win rate. Karthus has the advantage in this matchup. Sylas players should focus on safe farming and avoiding extended trades to minimize Karthus's lead.

How do I play Sylas against Karthus?

When playing Sylas against Karthus, play cautiously and avoid Karthus's power spikes. Look for jungle assistance and team-dependent plays since Karthus has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.