Kai'Sa - League of Legends Champion
Win Rate
49.4%
Pick Rate
5.1%

Kai'Savs Syndra

CMarksmanMage
Patch26.13
Matches177,854
LaneAll Lanes
TierAll Tiers
Last UpdatedJun 27, 2026
MethodologyData Methodology

Kai'Sa vs Syndra is a decisive matchup in LoL patch 26.13. Syndra wins with a 66.7% win rate (+33.3%) over Kai'Sa based on 6 games. Kai'Sa wins the early laning phase while Syndra scales better into the late game. Below you'll find the best Kai'Sa build, runes, laning stats, and strategies for the Kai'Sa vs Syndra matchup.

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Kai'Sa Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Kai'Sa performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Kai'Sa - 33.3% win rate in this matchup
Kai'Sa
33.3% WR
VS
Syndra vs Kai'Sa matchup - 66.7% win rate
Syndra
66.7% WR

Who Wins the Kai'Sa vs Syndra Matchup?

Syndra wins the Kai'Sa vs Syndra matchup
Winner
Syndra
Matches: 6
33.3%
Win Rate
66.7%
8.2
CS / min
6.7
956
DMG / min
922
15,859
Gold / game
13,630
174
Heal / min
65
446
DMG Mitigated / min
325
0.1
CC / min
1.6
50.0%
Early Game WR
50.0%
25.0%
Late Game WR
75.0%

Kai'Sa vs Syndra Matchup Summary

The Kai'Sa vs Syndra matchup is a decisive matchup in League of Legends ranked play. Based on 6 recent matches analyzed, Syndra wins with a 66.7% win rate compared to Kai'Sa's 33.3%, giving Syndra a 33.3 percentage point advantage. Game phase dynamics play a critical role here: Kai'Sa controls the early laning stage, but Syndra outscales as the game goes longer. The matchup shifts dramatically depending on game length — Kai'Sa needs to press advantages before Syndra reaches their power spikes, while Syndra should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Syndra leads by 1.5s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Syndra has a strong advantage in this matchup. Kai'Sa players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Syndra overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Kai'Sa vs Syndra Laning Phase Breakdown

Kai'Sa wins the laning phase against Syndra in League of Legends

Kai'Sa is favored during the laning phase against Syndra, winning 4 out of 5 key stat categories. Kai'Sa holds advantages in farming, damage, gold income and sustain, making them the stronger laner in this matchup.

Farming
8.2Kai'Sa
6.7Syndra
Kai'Sa significantly out-farms Syndra by 1.6 CS per minute, accumulating an estimated 23 CS lead by mid game. This substantial farming gap gives Kai'Sa a major gold advantage and earlier item completions. Syndra players should prioritize wave management techniques like freezing near tower and using abilities efficiently to minimize the deficit.
Damage
956Kai'Sa
922Syndra
Kai'Sa deals 34 more champion damage per minute than Syndra. While noticeable in extended trades, this gap can be offset by Syndra choosing favorable fight windows, such as engaging when Kai'Sa's key abilities are on cooldown or trading immediately after dodging a skillshot.
Economy
15,859Kai'Sa
13,630Syndra
Kai'Sa generates a commanding 2,229 more gold per game than Syndra. This substantial economic advantage means Kai'Sa consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Syndra should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.1Kai'Sa
1.6Syndra
Syndra brings significantly more crowd control than Kai'Sa, with 1.5 more seconds of CC per minute. This large utility gap makes Syndra far more valuable in setting up jungle ganks, controlling objectives, and locking down targets in team fights. Kai'Sa should invest in tenacity and position carefully to avoid being chain-CC'd.
Sustain
620Kai'Sa
390Syndra
Kai'Sa vastly out-sustains Syndra, healing and mitigating 230 more damage per minute. This massive durability gap means Kai'Sa can absorb significant punishment and remain in lane while Syndra is forced to recall. Building grievous wounds early is essential for Syndra, and focusing on burst trade patterns rather than sustained fights is critical.

Best Kai'Sa Build Against Syndra

Spellslinger's Shoes is the optimal boots choice against Syndra, providing the mobility and stats Kai'Sa needs most in this matchup. The top-performing core items for Kai'Sa against Syndra are Guinsoo's Rageblade, Phantom Dancer and Muramana. This combination gives Kai'Sa an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Kai'Sa vs Syndra matchup.

Early Game vs Late Game

Early Game
Kai'Sa
50.0%
+0.0% advantage
Kai'Sa early game win rateKai'Sa50.0%
Syndra early game win rateSyndra50.0%
Late Game
Syndra
75.0%
+50.0% advantage
Kai'Sa late game win rateKai'Sa25.0%
Syndra late game win rateSyndra75.0%

The early game (first 15 minutes) is a toss-up between Kai'Sa and Syndra, with Kai'Sa holding a razor-thin 50.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.

Syndra is far superior in the late game (25+ minutes), boasting a 75.0% win rate — 50.0 points above Kai'Sa. Extended games heavily favor Syndra, whose kit and scaling make them a dominant force in team fights and objective control.

The power dynamics shift as the game progresses — Kai'Sa has the edge early, but Syndra gradually takes over. However, the margins are slim enough that either champion can win at any stage with the right plays. Focus on taking advantages when you have them rather than waiting for a specific game phase.

Best Kai'Sa Runes Against Syndra

Precision rune tree - Kai'Sa primary runes vs SyndraPrecision
Lethal Tempo - best Kai'Sa rune vs SyndraPresence of Mind - best Kai'Sa rune vs SyndraLegend: Bloodline - best Kai'Sa rune vs SyndraCut Down - best Kai'Sa rune vs Syndra
Inspiration rune tree - Kai'Sa secondary runes vs SyndraInspiration
Biscuit Delivery - best Kai'Sa rune vs SyndraMagical Footwear - best Kai'Sa rune vs Syndra
100.0% WR

The Precision and Inspiration rune setup gives Kai'Sa the best tools to compete against Syndra in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Kai'Sa matchup data for League of Legends patch 26.13. The table below shows Kai'Sa's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Kai'Sa build, runes, laning stats, and early vs late game analysis for that specific matchup.

Kai'Sa matchup win rates and stats in League of Legends patch 26.13
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
55.48%1467.087714,47152.9%57.7%
48.48%1326.582813,82945.9%50.7%
53.44%1316.881513,50155.8%51.9%
47.29%1296.783313,57749.1%45.8%
48.78%1236.884513,51652.6%45.5%
57.14%986.993413,55757.5%56.9%
43.42%766.792613,77245.5%41.9%
45.33%756.879611,95042.9%48.5%
53.97%637.091714,86362.1%47.1%
45.16%626.977912,29051.5%37.9%
38.89%547.189814,06447.6%33.3%
56.00%506.884214,20547.4%61.3%
45.83%486.577312,36240.7%52.4%
46.81%477.284715,39273.7%28.6%
54.35%466.782513,69475.0%43.3%
56.52%466.885414,81158.8%55.2%
63.04%466.788713,04959.3%68.4%
55.88%347.382113,07160.0%50.0%
51.72%297.580312,68262.5%38.5%
57.14%286.687313,91371.4%42.9%
48.00%256.383714,62671.4%38.9%
38.10%217.480713,69466.7%16.7%
43.75%167.078513,01527.3%80.0%
57.14%146.584214,66375.0%50.0%
57.14%146.41,08115,41966.7%50.0%
57.14%146.878112,14550.0%66.7%
61.54%136.192413,57883.3%42.9%
41.67%126.592613,17033.3%50.0%
58.33%126.979514,69050.0%66.7%
41.67%127.077111,44737.5%50.0%
45.45%116.580911,14950.0%40.0%
54.55%116.479913,70466.7%40.0%
40.00%107.083711,44350.0%25.0%
62.50%87.078410,05540.0%100.0%
62.50%87.61,06411,22175.0%50.0%
25.00%86.31,04413,775100.0%14.3%
57.14%77.470311,65340.0%100.0%
42.86%75.896015,2850.0%50.0%
42.86%76.789714,29250.0%40.0%
33.33%68.295615,85950.0%25.0%
16.67%68.079917,8840.0%16.7%
66.67%66.81,13315,3430.0%80.0%

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Kai'Sa vs Syndra - Frequently Asked Questions

How does Kai'Sa do against Syndra in League of Legends?

Syndra wins the Kai'Sa vs Syndra matchup with a 66.7% win rate compared to Kai'Sa's 33.3%, a 33.3 percentage point difference. This data is based on 6 recent ranked games in patch 26.13.

How does Kai'Sa do against Syndra in the early game?

In the early game, Kai'Sa has the advantage against Syndra with a 50.0% win rate versus 50.0%. Kai'Sa players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Kai'Sa do against Syndra in the late game?

In the late game, Syndra takes over the Kai'Sa vs Syndra matchup with a 75.0% win rate compared to 25.0%. Syndra scales better into team fights and objective contests after 25 minutes.

Who wins the Kai'Sa vs Syndra matchup?

Syndra wins the matchup against Kai'Sa with a 66.7% win rate in League of Legends patch 26.13. The 33.3 percentage point advantage means Syndra is significantly favored in this lane matchup based on 6 games analyzed.

What is the best Kai'Sa build against Syndra?

The best Kai'Sa build against Syndra includes Guinsoo's Rageblade, Phantom Dancer, Muramana with Spellslinger's Shoes. Check the matchup breakdown above for the full item path and build order.

What are the best Kai'Sa runes against Syndra?

The best Kai'Sa runes against Syndra use the Precision primary tree with Inspiration secondary. This rune setup achieves a 100.0% win rate in the Kai'Sa vs Syndra matchup. See the full rune breakdown in the matchup comparison above.

Does Kai'Sa counter Syndra?

No, Kai'Sa struggles against Syndra with only a 33.3% win rate. Syndra has the advantage in this matchup. Kai'Sa players should focus on safe farming and avoiding extended trades to minimize Syndra's lead.

How do I play Kai'Sa against Syndra?

When playing Kai'Sa against Syndra, play cautiously and avoid Syndra's power spikes. Look for jungle assistance and team-dependent plays since Syndra has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.