Kai'Sa - League of Legends Champion
Win Rate
48.3%
Pick Rate
5.5%

Kai'Savs Syndra

FMarksmanMage
Patch26.3
Matches785,220
LaneAll Lanes
TierAll Tiers
Last UpdatedFeb 25, 2026
MethodologyData Methodology

Kai'Sa vs Syndra is a decisive matchup in LoL patch 26.3. Syndra wins with a 52.9% win rate (+5.9%) over Kai'Sa based on 17 games. Syndra wins the early laning phase while Kai'Sa scales better into the late game. Below you'll find the best Kai'Sa build, runes, laning stats, and strategies for the Kai'Sa vs Syndra matchup.

Kai'Sa Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Kai'Sa performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Syndra - 47.1% win rateSyndra(47.1%)
Kai'Sa - 47.1% win rate in this matchup
Kai'Sa
47.1% WR
VS
Syndra vs Kai'Sa matchup - 52.9% win rate
Syndra
52.9% WR

Who Wins the Kai'Sa vs Syndra Matchup?

Syndra wins the Kai'Sa vs Syndra matchup
Winner
Syndra
Matches: 17
47.1%
Win Rate
52.9%
6.5
CS / min
6.5
932
DMG / min
938
14,695
Gold / game
14,736
187
Heal / min
89
549
DMG Mitigated / min
342
0.1
CC / min
1.3
33.3%
Early Game WR
66.7%
54.5%
Late Game WR
45.5%

Kai'Sa vs Syndra Matchup Summary

The Kai'Sa vs Syndra matchup is a moderate matchup in League of Legends ranked play. Based on 17 recent matches analyzed, Syndra wins with a 52.9% win rate compared to Kai'Sa's 47.1%, giving Syndra a 5.9 percentage point advantage. Game phase dynamics play a critical role here: Syndra controls the early laning stage, but Kai'Sa outscales as the game goes longer. The matchup shifts dramatically depending on game length — Syndra needs to press advantages before Kai'Sa reaches their power spikes, while Kai'Sa should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Syndra leads by 1.2s CC/min — a difference that heavily influences the outcome of trades and skirmishes. While Syndra is slightly favored, Kai'Sa can absolutely win this lane through smart trading patterns and wave management. Focus on playing around your cooldowns, conceding CS only when necessary, and capitalizing on Syndra's mistakes. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Kai'Sa vs Syndra Laning Phase Breakdown

Syndra wins the laning phase against Kai'Sa in League of Legends

Syndra is favored during the laning phase against Kai'Sa, winning 4 out of 5 key stat categories. Syndra holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.

Farming
6.5Kai'Sa
6.5Syndra
Kai'Sa and Syndra farm at nearly identical rates in this matchup, with only a 0.0 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
932Kai'Sa
938Syndra
Damage output is virtually even between Kai'Sa and Syndra, with only 7 DMG/min separating them. Fights in this matchup are decided more by ability timing and positioning than raw damage numbers, making mechanical skill the deciding factor in trades.
Economy
14,695Kai'Sa
14,736Syndra
Kai'Sa and Syndra generate nearly equal gold per game, with just a 41 gold difference. Neither champion has a clear economic advantage, so gold leads will depend on individual play quality, kill participation, and objective contributions.
Utility
0.1Kai'Sa
1.3Syndra
Syndra brings significantly more crowd control than Kai'Sa, with 1.2 more seconds of CC per minute. This large utility gap makes Syndra far more valuable in setting up jungle ganks, controlling objectives, and locking down targets in team fights. Kai'Sa should invest in tenacity and position carefully to avoid being chain-CC'd.
Sustain
736Kai'Sa
431Syndra
Kai'Sa vastly out-sustains Syndra, healing and mitigating 305 more damage per minute. This massive durability gap means Kai'Sa can absorb significant punishment and remain in lane while Syndra is forced to recall. Building grievous wounds early is essential for Syndra, and focusing on burst trade patterns rather than sustained fights is critical.

Best Kai'Sa Build Against Syndra

Gunmetal Greaves is the optimal boots choice against Syndra, providing the mobility and stats Kai'Sa needs most in this matchup. The top-performing core items for Kai'Sa against Syndra are Kraken Slayer, Guinsoo's Rageblade and Nashor's Tooth. This combination gives Kai'Sa an effective balance of damage, survivability, and utility for the matchup. This build achieves a solid 50.0% win rate across 2 games, proving it to be a reliable item path when facing Syndra. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Kai'Sa vs Syndra matchup.

Early Game vs Late Game

Early Game
Syndra
66.7%
+33.3% advantage
Kai'Sa early game win rateKai'Sa33.3%
Syndra early game win rateSyndra66.7%
Late Game
Kai'Sa
54.5%
+9.1% advantage
Kai'Sa late game win rateKai'Sa54.5%
Syndra late game win rateSyndra45.5%

Syndra dominates the early game (first 15 minutes) with a commanding 66.7% win rate — a 33.3 percentage point lead over Kai'Sa. This lopsided early game means Syndra can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Kai'Sa is far superior in the late game (25+ minutes), boasting a 54.5% win rate — 9.1 points above Syndra. Extended games heavily favor Kai'Sa, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Syndra must aggressively press their early advantage and close out the game before Kai'Sa reaches their scaling breakpoints. If Kai'Sa survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Kai'Sa Runes Against Syndra

Precision rune tree - Kai'Sa primary runes vs SyndraPrecision
Lethal Tempo - best Kai'Sa rune vs SyndraTriumph - best Kai'Sa rune vs SyndraLegend: Bloodline - best Kai'Sa rune vs SyndraCut Down - best Kai'Sa rune vs Syndra
Inspiration rune tree - Kai'Sa secondary runes vs SyndraInspiration
Cash Back - best Kai'Sa rune vs SyndraTriple Tonic - best Kai'Sa rune vs Syndra
100.0% WR

The Precision and Inspiration rune setup gives Kai'Sa the best tools to compete against Syndra in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Kai'Sa matchup data for League of Legends patch 26.3. The table below shows Kai'Sa's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Kai'Sa build, runes, laning stats, and early vs late game analysis for that specific matchup.

Kai'Sa matchup win rates and stats in League of Legends patch 26.3
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
46.21%8856.885214,11249.8%43.1%
47.37%7606.987814,28746.7%48.0%
46.47%6806.680613,89247.4%45.7%
51.84%6256.887814,24148.7%54.8%
56.70%4557.090314,29153.4%59.8%
48.56%3836.990914,45854.3%44.3%
52.79%3776.786914,21555.9%49.5%
47.42%3297.092314,41447.2%47.6%
49.07%3246.989114,41655.6%42.6%
41.53%3136.882414,07445.6%37.8%
44.59%2966.684214,11346.5%43.2%
48.59%2497.186414,11946.8%50.4%
51.98%2276.887713,97050.4%53.8%
45.37%2166.690614,33749.1%41.8%
48.21%1956.691615,06040.5%53.5%
51.91%1837.190714,43355.6%48.4%
50.69%1446.985913,96655.7%44.6%
41.86%1297.088314,19446.3%37.1%
45.10%1026.892014,73252.4%40.0%
55.88%1027.197215,78660.0%53.2%
40.82%986.594613,96932.6%48.1%
51.09%927.096214,27956.6%43.6%
38.20%896.784113,90731.1%45.5%
61.80%897.294414,32859.2%65.0%
52.87%876.982714,97251.4%53.9%
35.62%736.989013,77537.1%34.2%
53.52%716.681714,76946.4%58.1%
48.15%546.996714,63040.0%58.3%
55.56%366.786314,73833.3%77.8%
51.52%336.879513,69943.8%58.8%
45.16%316.895914,85143.8%46.7%
56.67%306.468413,27350.0%62.5%
41.67%246.884214,77425.0%50.0%
43.48%237.289114,76360.0%30.8%
40.91%226.584112,76046.7%28.6%
47.06%176.593214,69533.3%54.5%
50.00%166.689112,53166.7%28.6%
40.00%156.984414,65133.3%44.4%
54.55%117.195310,79250.0%66.7%
40.00%106.273312,08037.5%50.0%
70.00%107.01,07014,72150.0%100.0%
40.00%106.675410,19342.9%33.3%
55.56%95.41,05215,68266.7%50.0%
33.33%97.067512,63520.0%50.0%
66.67%96.21,38613,892100.0%50.0%
33.33%97.31,07916,7700.0%50.0%
22.22%96.380611,92333.3%16.7%
44.44%97.01,08814,14850.0%40.0%
62.50%86.392515,97350.0%66.7%
57.14%76.765011,62850.0%66.7%
42.86%74.688015,65433.3%50.0%
71.43%77.81,05615,286100.0%60.0%
42.86%76.91,18615,12850.0%40.0%
57.14%76.292111,58150.0%100.0%
28.57%76.896913,1520.0%40.0%
0.00%65.388611,9660.0%0.0%
33.33%67.096214,53250.0%25.0%
16.67%67.485215,8890.0%20.0%
60.00%57.01,11613,41633.3%100.0%
60.00%56.082213,18150.0%66.7%
40.00%52.01,13915,50133.3%50.0%
60.00%57.11,07014,71050.0%66.7%
60.00%53.51,40118,343100.0%33.3%
40.00%57.01,20415,1140.0%66.7%
60.00%55.790815,2740.0%100.0%
0.00%53.11,03116,1900.0%0.0%
60.00%54.91,15114,33933.3%100.0%
60.00%50.982714,36866.7%50.0%
80.00%57.01,35716,83350.0%100.0%
80.00%55.885312,906100.0%66.7%
60.00%54.586413,987100.0%0.0%
20.00%56.91,23710,7690.0%33.3%
20.00%56.55598,46125.0%0.0%
40.00%53.01,25211,97450.0%33.3%
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Kai'Sa vs Syndra - Frequently Asked Questions

How does Kai'Sa do against Syndra in League of Legends?

Syndra wins the Kai'Sa vs Syndra matchup with a 52.9% win rate compared to Kai'Sa's 47.1%, a 5.9 percentage point difference. This data is based on 17 recent ranked games in patch 26.3.

How does Kai'Sa do against Syndra in the early game?

In the early game, Syndra has the advantage against Kai'Sa with a 66.7% win rate versus 33.3%. Syndra players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Kai'Sa do against Syndra in the late game?

In the late game, Kai'Sa takes over the Kai'Sa vs Syndra matchup with a 54.5% win rate compared to 45.5%. Kai'Sa scales better into team fights and objective contests after 25 minutes.

Who wins the Kai'Sa vs Syndra matchup?

Syndra wins the matchup against Kai'Sa with a 52.9% win rate in League of Legends patch 26.3. The 5.9 percentage point advantage means Syndra is significantly favored in this lane matchup based on 17 games analyzed.

What is the best Kai'Sa build against Syndra?

The best Kai'Sa build against Syndra includes Kraken Slayer, Guinsoo's Rageblade, Nashor's Tooth with Gunmetal Greaves. This build achieves a 50.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Kai'Sa runes against Syndra?

The best Kai'Sa runes against Syndra use the Precision primary tree with Inspiration secondary. This rune setup achieves a 100.0% win rate in the Kai'Sa vs Syndra matchup. See the full rune breakdown in the matchup comparison above.

Does Kai'Sa counter Syndra?

No, Kai'Sa struggles against Syndra with only a 47.1% win rate. Syndra has the advantage in this matchup. Kai'Sa players should focus on safe farming and avoiding extended trades to minimize Syndra's lead.

How do I play Kai'Sa against Syndra?

When playing Kai'Sa against Syndra, play cautiously and avoid Syndra's power spikes. Focus on safe farming — you outscale Syndra in the late game. Use the matchup-specific build and runes above to optimize your chances.