Twitch - League of Legends Champion
Win Rate
49.7%
Pick Rate
3.0%

Twitchvs Lissandra

CMarksmanAssassin
Patch26.10
Matches683,599
LaneAll Lanes
TierAll Tiers
Last UpdatedMay 17, 2026
MethodologyData Methodology

Twitch vs Lissandra is a decisive matchup in LoL patch 26.10. Twitch wins with a 100.0% win rate (+100.0%) over Lissandra based on 5 games. Twitch holds the advantage in both the early and late game. Below you'll find the best Twitch build, runes, laning stats, and strategies for the Twitch vs Lissandra matchup.

Twitch Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Twitch performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Lissandra - 100.0% win rateLissandra(100.0%)
Twitch - 100.0% win rate in this matchup
Twitch
100.0% WR
VS
Lissandra vs Twitch matchup - 0.0% win rate
Lissandra
0.0% WR

Who Wins the Twitch vs Lissandra Matchup?

Twitch wins the Twitch vs Lissandra matchup
Winner
Twitch
Matches: 5
100.0%
Win Rate
0.0%
6.3
CS / min
6.6
982
DMG / min
750
14,586
Gold / game
11,439
154
Heal / min
107
292
DMG Mitigated / min
406
0.3
CC / min
1.5
100.0%
Early Game WR
0.0%
100.0%
Late Game WR
0.0%

Twitch vs Lissandra Matchup Summary

The Twitch vs Lissandra matchup is a decisive matchup in League of Legends ranked play. Based on 5 recent matches analyzed, Twitch wins with a 100.0% win rate compared to Lissandra's 0.0%, giving Twitch a 100.0 percentage point advantage. Twitch dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Lissandra players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Lissandra leads by 1.3s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Twitch players can confidently pick into Lissandra and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Lissandra away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Twitch vs Lissandra Laning Phase Breakdown

Lissandra wins the laning phase against Twitch in League of Legends

Lissandra is favored during the laning phase against Twitch, winning 3 out of 5 key stat categories. Lissandra holds advantages in farming, crowd control and sustain, making them the stronger laner in this matchup.

Farming
6.3Twitch
6.6Lissandra
Lissandra edges out Twitch by 0.3 CS per minute — a moderate farming advantage that adds up to roughly 5 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Lissandra.
Damage
982Twitch
750Lissandra
Twitch heavily out-damages Lissandra by 232 DMG/min, dominating both short trades and all-in fights. Lissandra should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Twitch's sustained damage advantage take over.
Economy
14,586Twitch
11,439Lissandra
Twitch generates a commanding 3,146 more gold per game than Lissandra. This substantial economic advantage means Twitch consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Lissandra should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.3Twitch
1.5Lissandra
Lissandra brings significantly more crowd control than Twitch, with 1.3 more seconds of CC per minute. This large utility gap makes Lissandra far more valuable in setting up jungle ganks, controlling objectives, and locking down targets in team fights. Twitch should invest in tenacity and position carefully to avoid being chain-CC'd.
Sustain
446Twitch
513Lissandra
Lissandra heals and mitigates 67 more damage per minute than Twitch, providing moderate extra durability. This sustain edge allows Lissandra to stay in lane longer between recalls and gradually win extended wars of attrition. Consider building early grievous wounds if playing Twitch.

Best Twitch Build Against Lissandra

Gunmetal Greaves is the optimal boots choice against Lissandra, providing the mobility and stats Twitch needs most in this matchup. The top-performing core items for Twitch against Lissandra are The Collector, Nashor's Tooth and Runaan's Hurricane. This combination gives Twitch an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Lissandra. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Twitch vs Lissandra matchup.

Early Game vs Late Game

Early Game
Twitch
100.0%
+100.0% advantage
Twitch early game win rateTwitch100.0%
Lissandra early game win rateLissandra0.0%
Late Game
Twitch
100.0%
+100.0% advantage
Twitch late game win rateTwitch100.0%
Lissandra late game win rateLissandra0.0%

Twitch dominates the early game (first 15 minutes) with a commanding 100.0% win rate — a 100.0 percentage point lead over Lissandra. This lopsided early game means Twitch can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Twitch is far superior in the late game (25+ minutes), boasting a 100.0% win rate — 100.0 points above Lissandra. Extended games heavily favor Twitch, whose kit and scaling make them a dominant force in team fights and objective control.

Twitch holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Lissandra players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Twitch Runes Against Lissandra

Precision rune tree - Twitch primary runes vs LissandraPrecision
Lethal Tempo - best Twitch rune vs LissandraTriumph - best Twitch rune vs LissandraLegend: Alacrity - best Twitch rune vs LissandraCut Down - best Twitch rune vs Lissandra
Sorcery rune tree - Twitch secondary runes vs LissandraSorcery
Axiom Arcanist - best Twitch rune vs LissandraGathering Storm - best Twitch rune vs Lissandra
100.0% WR

Running Precision primary with Sorcery secondary allows Twitch to press their advantage against Lissandra, amplifying the strengths that make this a favorable matchup.


Twitch matchup data for League of Legends patch 26.10. The table below shows Twitch's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Twitch build, runes, laning stats, and early vs late game analysis for that specific matchup.

Twitch matchup win rates and stats in League of Legends patch 26.10
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
48.43%5726.099414,18545.2%50.8%
48.18%3305.790113,40044.9%50.8%
49.67%3025.790213,19643.1%55.7%
54.14%2905.896013,99147.6%59.1%
50.18%2715.582612,71049.2%51.0%
55.50%2185.895113,89551.8%57.9%
48.84%1725.995813,55437.3%57.7%
59.71%1396.097314,46758.9%60.2%
55.73%1315.887413,80750.9%59.0%
50.00%965.896313,70135.7%61.1%
55.43%925.787313,05254.5%56.3%
50.00%825.896513,88652.9%47.9%
58.54%825.892913,46264.9%53.3%
60.00%705.91,02614,64165.4%56.8%
42.62%615.595214,29939.1%44.7%
40.68%596.21,06414,71915.0%53.9%
50.85%595.287112,63446.4%54.8%
47.17%535.994814,85964.7%38.9%
41.18%515.796113,88140.9%41.4%
56.86%516.195913,99666.7%50.0%
42.00%505.791514,47952.6%35.5%
59.46%375.494613,70037.5%76.2%
45.71%354.279412,55738.5%50.0%
54.84%316.590813,60052.9%57.1%
33.33%306.082212,76129.4%38.5%
46.67%306.11,05214,53338.5%52.9%
35.71%285.391313,32233.3%37.5%
41.67%245.899714,64220.0%57.1%
43.48%234.776911,08741.7%45.5%
56.52%233.793513,57858.3%54.5%
52.63%195.479014,43040.0%57.1%
50.00%185.698914,07750.0%50.0%
41.18%172.071010,14844.4%37.5%
62.50%165.490512,67557.1%66.7%
43.75%164.998313,88260.0%36.4%
40.00%154.477010,98342.9%37.5%
42.86%143.892614,32850.0%40.0%
64.29%145.01,03712,26840.0%77.8%
33.33%121.674012,47450.0%16.7%
50.00%126.51,23016,63675.0%37.5%
20.00%102.287513,36825.0%16.7%
40.00%105.271211,07025.0%50.0%
80.00%105.196114,23066.7%85.7%
70.00%105.41,00914,18550.0%83.3%
40.00%105.21,12613,20733.3%42.9%
33.33%95.895013,96366.7%16.7%
44.44%94.476811,54360.0%25.0%
33.33%96.279113,86550.0%28.6%
44.44%95.81,00414,3900.0%57.1%
33.33%91.794314,87820.0%50.0%
75.00%81.987514,524100.0%66.7%
25.00%82.25758,52233.3%0.0%
50.00%82.496813,88633.3%60.0%
12.50%83.792710,73033.3%0.0%
25.00%86.01,12914,7520.0%50.0%
42.86%73.090212,5250.0%60.0%
42.86%71.66147,26450.0%0.0%
42.86%75.61,13116,358100.0%33.3%
33.33%65.27518,68140.0%0.0%
66.67%62.268012,22866.7%66.7%
66.67%62.066911,37950.0%75.0%
33.33%62.579812,5090.0%66.7%
66.67%65.494914,05350.0%75.0%
33.33%62.980011,68333.3%33.3%
66.67%61.478016,5270.0%66.7%
0.00%62.14048,1840.0%0.0%
66.67%61.386211,99066.7%66.7%
50.00%63.01,10515,6560.0%60.0%
83.33%65.51,11714,079100.0%80.0%
40.00%51.372114,7140.0%50.0%
40.00%54.792413,96050.0%33.3%
60.00%51.483811,73975.0%0.0%
20.00%56.092710,00933.3%0.0%
20.00%51.285113,4650.0%25.0%
20.00%52.470810,5190.0%25.0%
20.00%54.06818,26333.3%0.0%
20.00%53.155212,05933.3%0.0%
20.00%51.46689,4090.0%50.0%
80.00%51.464812,72550.0%100.0%
60.00%54.469911,59466.7%50.0%
100.00%56.398214,586100.0%100.0%
20.00%52.769314,31350.0%0.0%
40.00%52.393110,68925.0%100.0%
20.00%55.288813,5260.0%25.0%
40.00%54.385811,04333.3%50.0%

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Twitch vs Lissandra - Frequently Asked Questions

How does Twitch do against Lissandra in League of Legends?

Twitch wins the Twitch vs Lissandra matchup with a 100.0% win rate compared to Lissandra's 0.0%, a 100.0 percentage point difference. This data is based on 5 recent ranked games in patch 26.10.

How does Twitch do against Lissandra in the early game?

In the early game, Twitch has the advantage against Lissandra with a 100.0% win rate versus 0.0%. Twitch players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Twitch do against Lissandra in the late game?

In the late game, Twitch takes over the Twitch vs Lissandra matchup with a 100.0% win rate compared to 0.0%. Twitch scales better into team fights and objective contests after 25 minutes.

Who wins the Twitch vs Lissandra matchup?

Twitch wins the matchup against Lissandra with a 100.0% win rate in League of Legends patch 26.10. The 100.0 percentage point advantage means Twitch is significantly favored in this lane matchup based on 5 games analyzed.

What is the best Twitch build against Lissandra?

The best Twitch build against Lissandra includes The Collector, Nashor's Tooth, Runaan's Hurricane with Gunmetal Greaves. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Twitch runes against Lissandra?

The best Twitch runes against Lissandra use the Precision primary tree with Sorcery secondary. This rune setup achieves a 100.0% win rate in the Twitch vs Lissandra matchup. See the full rune breakdown in the matchup comparison above.

Does Twitch counter Lissandra?

Yes, Twitch has a favorable matchup against Lissandra with a 100.0% win rate. Twitch strongly counters Lissandra in lane based on current patch 26.10 data.

How do I play Twitch against Lissandra?

When playing Twitch against Lissandra, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.