Lissandra - League of Legends Champion
Win Rate
52.3%
Pick Rate
1.9%

Lissandravs Twitch

SMage
Patch26.10
Matches683,599
LaneAll Lanes
TierAll Tiers
Last UpdatedMay 18, 2026
MethodologyData Methodology

Lissandra vs Twitch is a decisive matchup in LoL patch 26.10. Twitch wins with a 100.0% win rate (+100.0%) over Lissandra based on 5 games. Twitch holds the advantage in both the early and late game. Below you'll find the best Lissandra build, runes, laning stats, and strategies for the Lissandra vs Twitch matchup.

Lissandra Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Lissandra performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Twitch - 0.0% win rateTwitch(0.0%)
Lissandra - 0.0% win rate in this matchup
Lissandra
0.0% WR
VS
Twitch vs Lissandra matchup - 100.0% win rate
Twitch
100.0% WR

Who Wins the Lissandra vs Twitch Matchup?

Twitch wins the Lissandra vs Twitch matchup
Winner
Twitch
Matches: 5
0.0%
Win Rate
100.0%
6.6
CS / min
6.3
750
DMG / min
982
11,439
Gold / game
14,586
107
Heal / min
154
406
DMG Mitigated / min
292
1.5
CC / min
0.3
0.0%
Early Game WR
100.0%
0.0%
Late Game WR
100.0%

Lissandra vs Twitch Matchup Summary

The Lissandra vs Twitch matchup is a decisive matchup in League of Legends ranked play. Based on 5 recent matches analyzed, Twitch wins with a 100.0% win rate compared to Lissandra's 0.0%, giving Twitch a 100.0 percentage point advantage. Twitch dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Lissandra players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Lissandra leads by 1.3s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Twitch has a strong advantage in this matchup. Lissandra players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Twitch overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Lissandra vs Twitch Laning Phase Breakdown

Lissandra wins the laning phase against Twitch in League of Legends

Lissandra is favored during the laning phase against Twitch, winning 3 out of 5 key stat categories. Lissandra holds advantages in farming, crowd control and sustain, making them the stronger laner in this matchup.

Farming
6.6Lissandra
6.3Twitch
Lissandra edges out Twitch by 0.3 CS per minute — a moderate farming advantage that adds up to roughly 5 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Lissandra.
Damage
750Lissandra
982Twitch
Twitch heavily out-damages Lissandra by 232 DMG/min, dominating both short trades and all-in fights. Lissandra should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Twitch's sustained damage advantage take over.
Economy
11,439Lissandra
14,586Twitch
Twitch generates a commanding 3,146 more gold per game than Lissandra. This substantial economic advantage means Twitch consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Lissandra should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
1.5Lissandra
0.3Twitch
Lissandra brings significantly more crowd control than Twitch, with 1.3 more seconds of CC per minute. This large utility gap makes Lissandra far more valuable in setting up jungle ganks, controlling objectives, and locking down targets in team fights. Twitch should invest in tenacity and position carefully to avoid being chain-CC'd.
Sustain
513Lissandra
446Twitch
Lissandra heals and mitigates 67 more damage per minute than Twitch, providing moderate extra durability. This sustain edge allows Lissandra to stay in lane longer between recalls and gradually win extended wars of attrition. Consider building early grievous wounds if playing Twitch.

Best Lissandra Build Against Twitch

Spellslinger's Shoes is the optimal boots choice against Twitch, providing the mobility and stats Lissandra needs most in this matchup. The top-performing core items for Lissandra against Twitch are Luden's Echo, Shadowflame and Morellonomicon. This combination gives Lissandra an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Lissandra vs Twitch matchup.

Early Game vs Late Game

Early Game
Twitch
100.0%
+100.0% advantage
Lissandra early game win rateLissandra0.0%
Twitch early game win rateTwitch100.0%
Late Game
Twitch
100.0%
+100.0% advantage
Lissandra late game win rateLissandra0.0%
Twitch late game win rateTwitch100.0%

Twitch dominates the early game (first 15 minutes) with a commanding 100.0% win rate — a 100.0 percentage point lead over Lissandra. This lopsided early game means Twitch can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Twitch is far superior in the late game (25+ minutes), boasting a 100.0% win rate — 100.0 points above Lissandra. Extended games heavily favor Twitch, whose kit and scaling make them a dominant force in team fights and objective control.

Twitch holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Lissandra players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Lissandra Runes Against Twitch

Domination rune tree - Lissandra primary runes vs TwitchDomination
Electrocute - best Lissandra rune vs TwitchCheap Shot - best Lissandra rune vs TwitchGrisly Mementos - best Lissandra rune vs TwitchUltimate Hunter - best Lissandra rune vs Twitch
Sorcery rune tree - Lissandra secondary runes vs TwitchSorcery
Manaflow Band - best Lissandra rune vs TwitchTranscendence - best Lissandra rune vs Twitch
0.0% WR

The Domination and Sorcery rune setup gives Lissandra the best tools to compete against Twitch in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Lissandra matchup data for League of Legends patch 26.10. The table below shows Lissandra's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Lissandra build, runes, laning stats, and early vs late game analysis for that specific matchup.

Lissandra matchup win rates and stats in League of Legends patch 26.10
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
52.35%1496.677111,28049.3%54.9%
54.35%1386.883812,17660.4%50.6%
55.56%1356.779712,02060.8%52.4%
58.82%1196.585711,81445.3%69.7%
53.85%1046.691412,01655.6%52.9%
50.98%1026.672711,35753.5%49.1%
50.00%806.886711,96240.0%56.0%
47.37%765.974811,29345.5%48.8%
45.21%736.568110,57627.3%60.0%
52.17%696.996112,15155.2%50.0%
53.13%646.588712,25569.2%42.1%
42.37%596.378711,75545.0%41.0%
41.38%586.680412,36452.2%34.3%
43.14%516.991310,43742.3%44.0%
42.86%427.390910,24141.7%44.4%
47.62%426.876010,09547.8%47.4%
43.59%396.492411,96047.1%40.9%
47.37%386.773912,00953.3%43.5%
60.53%386.682310,50361.9%58.8%
54.29%356.582911,10157.9%50.0%
55.88%346.288711,52147.1%64.7%
50.00%346.793312,04433.3%59.1%
43.33%306.375411,37862.5%36.4%
43.33%306.181910,81153.9%35.3%
50.00%306.783811,58266.7%38.9%
53.33%306.476812,25175.0%45.5%
65.52%297.089411,64469.2%62.5%
57.14%286.683111,94141.7%68.8%
50.00%286.680410,04369.2%33.3%
48.15%276.790212,52950.0%47.4%
40.74%277.088912,17457.1%35.0%
46.15%266.980410,29062.5%20.0%
30.77%266.793811,90144.4%23.5%
46.15%266.978211,53466.7%35.3%
29.17%245.895512,91442.9%23.5%
63.64%226.780410,92969.2%55.6%
61.90%216.279511,32762.5%61.5%
52.38%216.884811,51866.7%41.7%
45.00%207.185310,18254.5%33.3%
57.89%196.189310,29954.5%62.5%
33.33%186.465611,45037.5%30.0%
55.56%185.679210,17166.7%44.4%
17.65%175.868812,21714.3%20.0%
43.75%163.559310,75350.0%41.7%
68.75%166.588012,43080.0%63.6%
64.29%147.090011,20040.0%77.8%
42.86%147.176211,12255.6%20.0%
57.14%146.887914,155100.0%45.5%
46.15%136.683211,21450.0%40.0%
41.67%126.385814,250100.0%36.4%
75.00%125.977512,474100.0%66.7%
36.36%116.788512,71725.0%42.9%
72.73%116.678011,31550.0%85.7%
81.82%117.892313,197100.0%66.7%
70.00%106.681311,36880.0%60.0%
33.33%97.577010,76266.7%16.7%
33.33%96.773911,320100.0%14.3%
44.44%96.975912,01160.0%25.0%
50.00%83.780812,85866.7%40.0%
37.50%87.391710,19520.0%66.7%
62.50%87.589112,23766.7%60.0%
50.00%87.31,05311,45750.0%50.0%
25.00%81.54948,3330.0%40.0%
50.00%82.75139,630100.0%33.3%
50.00%87.01,06011,42833.3%60.0%
62.50%86.091112,81766.7%60.0%
25.00%87.080111,32920.0%33.3%
50.00%86.11,00311,85340.0%66.7%
12.50%85.575810,4670.0%14.3%
57.14%72.462312,2880.0%57.1%
42.86%71.85527,24760.0%0.0%
28.57%76.783812,06833.3%25.0%
57.14%76.57077,45375.0%33.3%
28.57%77.01,20012,84850.0%20.0%
71.43%77.094211,67033.3%100.0%
50.00%67.596513,326100.0%25.0%
83.33%67.61,02412,158100.0%66.7%
33.33%65.176510,856100.0%20.0%
33.33%66.278310,96850.0%25.0%
66.67%64.367711,77250.0%75.0%
83.33%66.51,01112,025100.0%75.0%
60.00%56.28127,81460.0%0.0%
80.00%56.994810,95466.7%100.0%
0.00%56.675011,4390.0%0.0%
40.00%56.880213,193100.0%25.0%
20.00%56.692910,16050.0%0.0%
40.00%56.992711,982100.0%25.0%

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Lissandra vs Twitch - Frequently Asked Questions

How does Lissandra do against Twitch in League of Legends?

Twitch wins the Lissandra vs Twitch matchup with a 100.0% win rate compared to Lissandra's 0.0%, a 100.0 percentage point difference. This data is based on 5 recent ranked games in patch 26.10.

How does Lissandra do against Twitch in the early game?

In the early game, Twitch has the advantage against Lissandra with a 100.0% win rate versus 0.0%. Twitch players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Lissandra do against Twitch in the late game?

In the late game, Twitch takes over the Lissandra vs Twitch matchup with a 100.0% win rate compared to 0.0%. Twitch scales better into team fights and objective contests after 25 minutes.

Who wins the Lissandra vs Twitch matchup?

Twitch wins the matchup against Lissandra with a 100.0% win rate in League of Legends patch 26.10. The 100.0 percentage point advantage means Twitch is significantly favored in this lane matchup based on 5 games analyzed.

What is the best Lissandra build against Twitch?

The best Lissandra build against Twitch includes Luden's Echo, Shadowflame, Morellonomicon with Spellslinger's Shoes. Check the matchup breakdown above for the full item path and build order.

What are the best Lissandra runes against Twitch?

The best Lissandra runes against Twitch use the Domination primary tree with Sorcery secondary. This rune setup achieves a 0.0% win rate in the Lissandra vs Twitch matchup. See the full rune breakdown in the matchup comparison above.

Does Lissandra counter Twitch?

No, Lissandra struggles against Twitch with only a 0.0% win rate. Twitch has the advantage in this matchup. Lissandra players should focus on safe farming and avoiding extended trades to minimize Twitch's lead.

How do I play Lissandra against Twitch?

When playing Lissandra against Twitch, play cautiously and avoid Twitch's power spikes. Look for jungle assistance and team-dependent plays since Twitch has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.