- Win Rate
- 51.2%
- Pick Rate
- 1.2%
- Ban Rate
- 0.7%
Zeri ADC Runes: Keystone & Shards
- Patch
- 26.21
- Games
- 2,412
- Lane
- Bot
- Tier
- All Tiers
- Last Updated
- Nov 3, 2026 UTC
- Author
- Dakota Chinnick
- Methodology
- Data Methodology
Best Bot Zeri runes for LoL Patch 26.21 - Lethal Tempo from the Precision tree with Inspiration secondary (51.1% WR, 30.2% pick rate). Zeri's optimal primary runes are Lethal Tempo, Triumph, Legend: Bloodline, Cut Down. Secondary tree: Cash Back, Triple Tonic.
Primary Tree
Precision
Lethal TempoAttacking an enemy champion grants you [6% Melee || 4% Ranged] Attack Speed for 6 seconds, up to 6. At max stacks, deal [9 - 30 Melee || 6 - 24 Ranged]
TriumphTakedowns restore 5% of your missing health, 2.5% of your max health, and grant an additional 20 gold.
'The most dangerous game brings the greatest glory.'
—Noxian Reckoner
Legend: BloodlineGain
Earn progress toward Legend stacks for every champion takedown, epic monster takedown, large monster kill, and minion kill.
Cut DownDeal 8% more damage to champions who have more than 60% health.
Cash BackGet 7.5% Gold back when you purchase Legendary Items.
Triple TonicUpon reaching level 3, gain an Elixir of Avarice.
Upon reaching level 6, gain an Elixir of Force.
Upon reaching level 9, gain an Elixir of Skill.
Primary Tree
Precision
Lethal TempoAttacking an enemy champion grants you [6% Melee || 4% Ranged] Attack Speed for 6 seconds, up to 6. At max stacks, deal [9 - 30 Melee || 6 - 24 Ranged]
TriumphTakedowns restore 5% of your missing health, 2.5% of your max health, and grant an additional 20 gold.
'The most dangerous game brings the greatest glory.'
—Noxian Reckoner
Legend: AlacrityGain 3% attack speed plus an additional 1.5% for every Legend stack (
Earn progress toward Legend stacks for every champion takedown, epic monster takedown, large monster kill, and minion kill.
Last StandDeal 5% - 11% increased damage to champions while you are below 60% health. Max damage gained at 30% health.
ConditioningAfter 12 min gain +8 Armor and +8 Magic Resist and increase your Armor and Magic Resist by 3%.
OvergrowthAbsorb life essence from monsters or enemy minions that die near you, permanently gaining 3 maximum health for every 8.
When you've absorbed 120 monsters or enemy minions, gain an additional 3.5% maximum health.
Every Zeri Bot Keystone and Secondary Tree (Patch 26.21)
2,319 gamesZeri Bot runs Lethal Tempo in 90% of games, with a 52.0% win rate. Inspiration is the usual secondary tree (54%). Standard stat shards: Attack Speed (offense), Adaptive Force (flex), Health (defense).
Keystones
| Rune | Players | Win Rate | Games |
|---|---|---|---|
| Lethal TempoMost played | 90.2% | 52.0% | 2,092 |
 Fleet Footwork | 5.7% | 44.4% | 133 |
 Conqueror | 2.7% | 51.6% | 62 |
Secondary trees
| Rune | Players | Win Rate | Games |
|---|---|---|---|
 InspirationMost played | 53.8% | 50.8% | 1,247 |
 Resolve | 41.6% | 52.1% | 964 |
 Sorcery | 3.3% | 48.7% | 76 |
Pick rate is the share of Zeri games in this lane that used the rune; options under 40 games are left out. A higher win rate on a rarely picked rune is usually a matchup-specific choice, not a general upgrade.
Zeri Minor Runes by Tree
Every minor rune Zeri players take, grouped by rune tree, with how often it is picked and how often it wins.
Precision
| Rune | Players | Win Rate | Games |
|---|---|---|---|
| TriumphMost played | 96.4% | 51.7% | 2,235 |
| Cut Down | 59.3% | 51.5% | 1,375 |
| Legend: Alacrity | 53.4% | 51.0% | 1,239 |
| Legend: Bloodline | 46.0% | 51.4% | 1,066 |
| Last Stand | 36.6% | 50.7% | 848 |
 Coup de Grace | 3.6% | 51.8% | 83 |
Inspiration
| Rune | Players | Win Rate | Games |
|---|---|---|---|
| Cash BackMost played | 51.7% | 50.8% | 1,199 |
| Triple Tonic | 44.3% | 51.3% | 1,027 |
 Cosmic Insight | 7.4% | 50.6% | 172 |
 Biscuit Delivery | 2.7% | 34.9% | 63 |
Resolve
| Rune | Players | Win Rate | Games |
|---|---|---|---|
| OvergrowthMost played | 39.5% | 51.9% | 917 |
| Conditioning | 37.2% | 51.7% | 863 |
 Bone Plating | 3.5% | 58.5% | 82 |
Sorcery
| Rune | Players | Win Rate | Games |
|---|---|---|---|
 Gathering StormMost played | 2.2% | 50.0% | 52 |
 Celerity | 1.9% | 53.5% | 43 |
Zeri Stat Shards
Which stat shards Zeri players choose in each of the three shard rows, and the win rate of each.
| Rune | Players | Win Rate | Games |
|---|---|---|---|
 Attack Speed (offense)Most played | 97.1% | 51.1% | 2,252 |
 Adaptive Force (flex) | 96.8% | 51.2% | 2,245 |
 Health (defense) | 53.6% | 51.4% | 1,242 |
| Health Scaling (defense) | 43.9% | 51.2% | 1,019 |
 Move Speed (flex) | 3.0% | 51.4% | 70 |
| Adaptive Force (offense) | 2.8% | 53.0% | 66 |
 Tenacity and Slow Resist (defense) | 2.5% | 43.1% | 58 |
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Zeri Runes FAQ - Patch 26.21
What is the best keystone for Zeri Bot?
Lethal Tempo: Zeri Bot takes it in 90% of ranked games and wins 52.0% of 2,092 games. Alternatives: Fleet Footwork (6%, 44.4%), Conqueror (3%, 51.6%).
What stat shards should Zeri take?
Most Zeri players take Attack Speed (offense), Adaptive Force (flex), Health (defense) — one from each shard row.
What are the best Zeri runes in patch 26.21?
The best Zeri runes in patch 26.21 use the Precision tree with Lethal Tempo, Triumph, Legend: Bloodline, and Cut Down, and the Inspiration tree with Cash Back and Triple Tonic. This rune setup achieves a 51.1% win rate with a 30.2% pick rate.
What is the win rate for Zeri's best rune page?
Zeri's best rune page has a 51.1% win rate in patch 26.21, which is -0.1% compared to Zeri's average win rate. This rune setup has a 30.2% pick rate among Zeri players.
What keystone should I use on Zeri?
Lethal Tempo from the Precision tree is the best keystone rune for Zeri in patch 26.21. This keystone synergizes well with Zeri's kit and provides a 51.1% win rate.
What is Zeri's primary rune tree?
Zeri's primary rune tree is Precision. The optimal Precision runes for Zeri are Lethal Tempo, Triumph, Legend: Bloodline, and Cut Down, with Lethal Tempo being the keystone of choice.
What is Zeri's secondary rune tree?
Zeri's best secondary rune tree is Inspiration. The recommended Inspiration runes are Cash Back and Triple Tonic, which complement Zeri's Precision primary tree.
What are alternative rune setups for Zeri?
An alternative Zeri rune setup uses Lethal Tempo from the Precision tree. This alternate build may be preferred in certain matchups or playstyles. Check the alternative rune page above for full details including win rate and pick rate.
How popular are Zeri's runes?
Zeri's top rune page has a 30.2% pick rate in patch 26.21. This indicates that 30.2% of Zeri players use the Lethal Tempo setup with Precision and Inspiration trees.