Kai'Sa Runes
Best Kai'Sa runes for LoL Patch 26.1 - Lethal Tempo from the Precision tree with Inspiration secondary (82.4% WR, 0.3% pick rate). Kai'Sa's optimal primary runes are Lethal Tempo, Triumph, Legend: Alacrity, Cut Down. Secondary tree: Triple Tonic, Cash Back.
Second Skin
Kai'Sa's basic attacks stack Plasma, dealing increasing bonus magic damage. Allies' immobilizing effects help stack Plasma. Additionally, Kai'Sa's item purchases upgrade her basic spells to have more powerful properties.
Icathian Rain
Kai'Sa shoots a swarm of missiles that seek out nearby targets.
Living Weapon: Icathian Rain is upgraded to shoot more missiles.Cost:- 55
Cooldown:- 10/
- 9/
- 8/
- 7/
- 6
Range:- 600
Void Seeker
Kai'Sa shoots a long range missile, marking enemies with her passive.
Living Weapon: Void Seeker is upgraded to apply more passive marks and reduce cooldown on champion hit.Cost:- 55/
- 60/
- 65/
- 70/
- 75
Cooldown:- 22/
- 20/
- 18/
- 16/
- 14
Range:- 3000
Supercharge
Kai'Sa briefly increases her Move Speed, then increases her Attack Speed.
Living Weapon: Supercharge is upgraded to briefly grant Invisibility.Cost:- 30
Cooldown:- 16/
- 15/
- 13/
- 12/
- 10
Range:- 1
Killer Instinct
Kai'Sa dashes near an enemy champion.
Cost:- 100
Cooldown:- 130/
- 100/
- 70
Range:- 2000/
- 2500/
- 3000
- Marksman,
- Mage
Kai'Sa performs best with Lethal Tempo as the keystone rune from the Precision tree. Kai'Sa's optimal primary runes are Lethal Tempo, Triumph, Legend: Alacrity, Cut Down. Kai'Sa's secondary rune tree is Inspiration with Triple Tonic, Cash Back. This rune setup achieves a 82.35% win rate (+35.0% win rate difference) with a 0.3% pick rate across 17 Kai'Sa games.
Primary Tree
Precision
Lethal TempoAttacking an enemy champion grants you [6% Melee || 4% Ranged] Attack Speed for 6 seconds, up to 6. At max stacks, deal [9 - 30 Melee || 6 - 24 Ranged]
TriumphTakedowns restore 5% of your missing health, 2.5% of your max health, and grant an additional 20 gold.
'The most dangerous game brings the greatest glory.'
—Noxian Reckoner
Legend: AlacrityGain 3% attack speed plus an additional 1.5% for every Legend stack (
Earn progress toward Legend stacks for every champion takedown, epic monster takedown, large monster kill, and minion kill.
Cut DownDeal 8% more damage to champions who have more than 60% health.
Triple TonicUpon reaching level 3, gain an Elixir of Avarice.
Upon reaching level 6, gain an Elixir of Force.
Upon reaching level 9, gain an Elixir of Skill.
Cash BackGet 8% Gold back when you purchase Legendary Items.
This alternative Kai'Sa rune build uses Lethal Tempo as the keystone from the Precision tree. The primary runes are Lethal Tempo, Presence of Mind, Legend: Bloodline, Coup de Grace. Kai'Sa's secondary rune tree is Domination with Taste of Blood, Treasure Hunter. This setup achieves a 66.67% win rate (+19.3% win rate difference) with a 0.3% pick rate across 18 games.
Primary Tree
Precision
Lethal TempoAttacking an enemy champion grants you [6% Melee || 4% Ranged] Attack Speed for 6 seconds, up to 6. At max stacks, deal [9 - 30 Melee || 6 - 24 Ranged]
Presence of MindDamaging an enemy champion restores 6-50 (80% for ranged) mana or 6 energy.
Takedowns restore 15% of your maximum mana or energy.
Cooldown for damage restoration: 8s
Legend: BloodlineGain
Earn progress toward Legend stacks for every champion takedown, epic monster takedown, large monster kill, and minion kill.
Coup de GraceDeal 8% more damage to champions who have less than 40% health.
Taste of BloodHeal when you damage an enemy champion.
Healing: 16-40 (+0.1 bonus AD, +0.05 AP) health (based on level)
Cooldown: 20s
Treasure HunterGain an additional
Bounty Hunter stacks are earned the first time you get a takedown on each enemy champion.
Kai'Sa Runes - Frequently Asked Questions
What are the best Kai'Sa runes in patch 26.1?
The best Kai'Sa runes in patch 26.1 use the Precision tree with Lethal Tempo, Triumph, Legend: Alacrity, and Cut Down, and the Inspiration tree with Triple Tonic and Cash Back. This rune setup achieves a 82.4% win rate with a 0.3% pick rate.
What is the win rate for Kai'Sa's best rune page?
Kai'Sa's best rune page has a 82.4% win rate in patch 26.1, which is +35.0% compared to Kai'Sa's average win rate. This rune setup has a 0.3% pick rate among Kai'Sa players.
What keystone should I use on Kai'Sa?
Lethal Tempo from the Precision tree is the best keystone rune for Kai'Sa in patch 26.1. This keystone synergizes well with Kai'Sa's kit and provides a 82.4% win rate.
What is Kai'Sa's primary rune tree?
Kai'Sa's primary rune tree is Precision. The optimal Precision runes for Kai'Sa are Lethal Tempo, Triumph, Legend: Alacrity, and Cut Down, with Lethal Tempo being the keystone of choice.
What is Kai'Sa's secondary rune tree?
Kai'Sa's best secondary rune tree is Inspiration. The recommended Inspiration runes are Triple Tonic and Cash Back, which complement Kai'Sa's Precision primary tree.
What are alternative rune setups for Kai'Sa?
An alternative Kai'Sa rune setup uses Lethal Tempo from the Precision tree. This alternate build may be preferred in certain matchups or playstyles. Check the alternative rune page above for full details including win rate and pick rate.
How popular are Kai'Sa's runes?
Kai'Sa's top rune page has a 0.3% pick rate in patch 26.1. This indicates that 0.3% of Kai'Sa players use the Lethal Tempo setup with Precision and Inspiration trees.