Kai'Sa Runes
The top Kai'Sa runes in LoL patch 25.23 are Press the Attack, Triumph, Legend: Bloodline, Coup de Grace for Kai'Sa's primary runes. Kai'Sa's runes in his secondary tree best utilizes Taste of Blood and Relentless Hunter. These Kai'Sa rune choices provide the best Kai'Sa rune build for ranked.
Second Skin
Kai'Sa's basic attacks stack Plasma, dealing increasing bonus magic damage. Allies' immobilizing effects help stack Plasma. Additionally, Kai'Sa's item purchases upgrade her basic spells to have more powerful properties.
Icathian Rain
Kai'Sa shoots a swarm of missiles that seek out nearby targets.
Living Weapon: Icathian Rain is upgraded to shoot more missiles.Cost:- 55
Cooldown:- 10/
- 9/
- 8/
- 7/
- 6
Range:- 600
Void Seeker
Kai'Sa shoots a long range missile, marking enemies with her passive.
Living Weapon: Void Seeker is upgraded to apply more passive marks and reduce cooldown on champion hit.Cost:- 55/
- 60/
- 65/
- 70/
- 75
Cooldown:- 22/
- 20/
- 18/
- 16/
- 14
Range:- 3000
Supercharge
Kai'Sa briefly increases her Move Speed, then increases her Attack Speed.
Living Weapon: Supercharge is upgraded to briefly grant Invisibility.Cost:- 30
Cooldown:- 16/
- 15/
- 13/
- 12/
- 10
Range:- 1
Killer Instinct
Kai'Sa dashes near an enemy champion.
Cost:- 100
Cooldown:- 130/
- 100/
- 70
Range:- 2000/
- 2500/
- 3000
- Marksman,
- Mage
Kai'Sa performs best with Press the Attack as the keystone rune. The optimal primary runes for Kai'Sa include Press the Attack, Triumph, Legend: Bloodline. This rune setup achieves a 1.00% win rate across 1 Kai'Sa games.
Primary Tree
Precision
This alternative Kai'Sa rune build uses Fleet Footwork as the keystone. This setup provides a different playstyle for Kai'Sa and achieves a 1.00% win rate. Consider this rune page when facing specific matchups or team compositions.
Primary Tree
Precision
Kai'Sa Runes - Frequently Asked Questions
What are the best Kai'Sa runes?
The best Kai'Sa runes in patch 25.23 are Press the Attack, Triumph, Legend: Bloodline, and Coup de Grace for the primary tree, and Taste of Blood and Relentless Hunter for the secondary tree. These runes provide optimal performance for Kai'Sa.
What keystone should I use on Kai'Sa?
Press the Attack is the best keystone rune for Kai'Sa. This keystone synergizes well with Kai'Sa's abilities and provides maximum value in most matchups.
What are Kai'Sa's secondary runes?
Kai'Sa's best secondary runes are Taste of Blood and Relentless Hunter. These secondary runes complement Kai'Sa's primary rune choices and enhance overall effectiveness.
Can I use different rune setups on Kai'Sa?
Yes, Kai'Sa can utilize different rune setups depending on matchup and playstyle. While Press the Attack is most popular, alternative keystones may work better in specific situations.
