Kai'Sa, League of Legends champion
Win Rate
50.0%
Pick Rate
10.7%
Ban Rate
4.2%

Kai'Sa ADC Runes: Keystone & Shards

Kai'Sa A TierMarksmanMage
Patch
26.22
Games
13,867
Lane
Bot
Tier
Emerald+
Last Updated
Nov 14, 2026 UTC
Methodology
Data Methodology

Best Kai'Sa Emerald+ Bot runes for LoL Patch 26.22: Lethal Tempo in 96% of games (49.9% win rate) with Inspiration. Every keystone, minor rune and shard by win rate.

Keystone
Lethal Tempo96% of games · 49.9% win rate
Secondary tree
Inspiration96% of games
Shards
Adaptive Force (flex)
Summoner spells
Flash + Barrier58% of games
Ranked games
13,867
Kai'Sa performs best with Lethal Tempo as the keystone rune from the Precision tree. Kai'Sa's optimal primary runes are Lethal Tempo, Presence of Mind, Legend: Bloodline, Cut Down. Kai'Sa's secondary rune tree is Inspiration with Magical Footwear, Triple Tonic. This rune setup achieves a 76.19% win rate (+26.2% win rate difference) with a 0.1% pick rate across 21 Kai'Sa games.
76.2%Win Rate
+26.2%WR Diff
0.1%Pick Rate
Lethal Tempo – League of Legends runeLethal Tempo

Attacking an enemy champion grants you [6% Melee || 4% Ranged] Attack Speed for 6 seconds, up to 6. At max stacks, deal [9 - 30 Melee || 6 - 24 Ranged] bonus adaptive damage On-Attack, increased by 1% per 1% Bonus Attack Speed.

Presence of Mind – League of Legends runePresence of Mind

Damaging an enemy champion restores 6-50 (80% for ranged) mana or 6 energy.

Takedowns restore 15% of your maximum mana or energy.

Cooldown for damage restoration: 8s

Legend: Bloodline – League of Legends runeLegend: Bloodline

Gain 0.45% Life Steal for every Legend stack (max 15 stacks). At maximum Legend stacks, gain 85 max health.

Earn progress toward Legend stacks for every champion takedown, epic monster takedown, large monster kill, and minion kill.

Cut Down – League of Legends runeCut Down

Deal 8% more damage to champions who have more than 60% health.

Magical Footwear – League of Legends runeMagical Footwear

You get free Slightly Magical Footwear at 12 min, but you cannot buy boots before then. For each takedown you acquire the boots 45s sooner.

Slightly Magical Footwear grants you an additional 10 Move Speed.

Triple Tonic – League of Legends runeTriple Tonic

Upon reaching level 3, gain an Elixir of Avarice.
Upon reaching level 6, gain an Elixir of Force.
Upon reaching level 9, gain an Elixir of Skill.

This alternative Kai'Sa rune build uses Lethal Tempo as the keystone from the Precision tree. The primary runes are Lethal Tempo, Presence of Mind, Legend: Alacrity, Cut Down. Kai'Sa's secondary rune tree is Inspiration with Cash Back, Triple Tonic. This setup achieves a 61.84% win rate (+11.9% win rate difference) with a 0.5% pick rate across 76 games.
61.8%Win Rate
+11.9%WR Diff
0.5%Pick Rate
Lethal Tempo – League of Legends runeLethal Tempo

Attacking an enemy champion grants you [6% Melee || 4% Ranged] Attack Speed for 6 seconds, up to 6. At max stacks, deal [9 - 30 Melee || 6 - 24 Ranged] bonus adaptive damage On-Attack, increased by 1% per 1% Bonus Attack Speed.

Presence of Mind – League of Legends runePresence of Mind

Damaging an enemy champion restores 6-50 (80% for ranged) mana or 6 energy.

Takedowns restore 15% of your maximum mana or energy.

Cooldown for damage restoration: 8s

Legend: Alacrity – League of Legends runeLegend: Alacrity

Gain 3% attack speed plus an additional 1.5% for every Legend stack (max 10 stacks).

Earn progress toward Legend stacks for every champion takedown, epic monster takedown, large monster kill, and minion kill.

Cut Down – League of Legends runeCut Down

Deal 8% more damage to champions who have more than 60% health.

Cash Back – League of Legends runeCash Back

Get 7.5% Gold back when you purchase Legendary Items.

Triple Tonic – League of Legends runeTriple Tonic

Upon reaching level 3, gain an Elixir of Avarice.
Upon reaching level 6, gain an Elixir of Force.
Upon reaching level 9, gain an Elixir of Skill.

These champions share at least 4 runes with Kai'Sa's recommended rune builds. use similar keystone and secondary runes, making them good alternatives if you enjoy Kai'Sa's playstyle or want to learn champions with familiar rune setups.Corki, Yunara, Caitlyn, Ashe, Jinx and 5 others
MetaBot Desktop

Auto-import Kai'Sa's best runes in champ select

Turn on auto-import and MetaBot Desktop applies the highest win-rate rune page when you pick a champion, adds a MetaBot item set to your shop and sets your summoner spells, keeping your Flash slot.

  • Rune page applied on pick
  • Item set added to your shop
  • Summoners set, Flash kept
MetaBot Desktop's champ select overlay importing runes, items and summoner spells

Every Kai'Sa Bot Keystone and Secondary Tree (Patch 26.22)

13,867 games

Kai'Sa Bot runs Lethal Tempo in 96% of games, with a 49.9% win rate. Inspiration is the usual secondary tree (96%). Standard stat shards: Attack Speed (offense), Adaptive Force (flex), Health Scaling (defense).

Keystones

RunePlayersWin RateGames
Lethal Tempo – League of Legends runeLethal TempoMost played95.9%49.9%13,292
Press the Attack – League of Legends runePress the Attack3.5%49.9%479

Secondary trees

RunePlayersWin RateGames
Inspiration – League of Legends runeInspirationMost played96.0%50.0%13,317
Domination – League of Legends runeDomination2.0%48.4%273
Sorcery – League of Legends runeSorcery1.3%52.0%177

Pick rate is the share of Kai'Sa games in this lane that used the rune; options under 40 games are left out. A higher win rate on a rarely picked rune is usually a matchup-specific choice, not a general upgrade.

Kai'Sa Minor Runes by Tree

Every minor rune Kai'Sa players take, grouped by rune tree, with how often it is picked and how often it wins.

Precision

RunePlayersWin RateGames
Legend: Bloodline – League of Legends runeLegend: BloodlineMost played83.8%49.8%11,620
Presence of Mind – League of Legends runePresence of Mind59.2%49.3%8,206
Cut Down – League of Legends runeCut Down52.4%50.8%7,270
Coup de Grace – League of Legends runeCoup de Grace46.8%48.8%6,490
Triumph – League of Legends runeTriumph39.8%51.0%5,514
Legend: Alacrity – League of Legends runeLegend: Alacrity15.1%50.7%2,098

Inspiration

RunePlayersWin RateGames
Cash Back – League of Legends runeCash BackMost played51.8%50.6%7,180
Magical Footwear – League of Legends runeMagical Footwear41.0%49.1%5,685
Biscuit Delivery – League of Legends runeBiscuit Delivery40.4%48.7%5,600
Cosmic Insight – League of Legends runeCosmic Insight33.0%50.4%4,570
Triple Tonic – League of Legends runeTriple Tonic24.7%51.9%3,423
Jack Of All Trades – League of Legends runeJack Of All Trades1.4%50.0%192

Domination

RunePlayersWin RateGames
Taste of Blood – League of Legends runeTaste of BloodMost played1.9%47.7%258
Treasure Hunter – League of Legends runeTreasure Hunter1.8%48.6%253

Sorcery

RunePlayersWin RateGames
Gathering Storm – League of Legends runeGathering StormMost played1.1%52.0%148
Absolute Focus – League of Legends runeAbsolute Focus0.6%57.1%77

Kai'Sa Stat Shards

Which stat shards Kai'Sa players choose in each of the three shard rows, and the win rate of each.

RunePlayersWin RateGames
Adaptive Force (flex) – League of Legends runeAdaptive Force (flex)Most played99.6%49.9%13,808
Attack Speed (offense) – League of Legends runeAttack Speed (offense)97.7%49.8%13,543
Health Scaling (defense) – League of Legends runeHealth Scaling (defense)51.0%49.4%7,078
Health (defense) – League of Legends runeHealth (defense)48.6%50.5%6,740
Adaptive Force (offense) – League of Legends runeAdaptive Force (offense)2.3%54.3%317
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Kai'Sa Runes FAQ - Patch 26.22

What is the best keystone for Kai'Sa Bot?

Lethal Tempo: Kai'Sa Bot takes it in 96% of ranked games and wins 49.9% of 13,292 games. Alternatives: Press the Attack (3%, 49.9%).

What stat shards should Kai'Sa take?

Most Kai'Sa players take Attack Speed (offense), Adaptive Force (flex), Health Scaling (defense) — one from each shard row.

What are the best Kai'Sa runes in patch 26.22?

The best Kai'Sa runes in patch 26.22 use the Precision tree with Lethal Tempo, Presence of Mind, Legend: Bloodline, and Cut Down, and the Inspiration tree with Magical Footwear and Triple Tonic. This rune setup achieves a 76.2% win rate with a 0.1% pick rate.

What is the win rate for Kai'Sa's best rune page?

Kai'Sa's best rune page has a 76.2% win rate in patch 26.22, which is +26.2% compared to Kai'Sa's average win rate. This rune setup has a 0.1% pick rate among Kai'Sa players.

What keystone should I use on Kai'Sa?

Lethal Tempo from the Precision tree is the best keystone rune for Kai'Sa in patch 26.22. This keystone synergizes well with Kai'Sa's kit and provides a 76.2% win rate.

What is Kai'Sa's primary rune tree?

Kai'Sa's primary rune tree is Precision. The optimal Precision runes for Kai'Sa are Lethal Tempo, Presence of Mind, Legend: Bloodline, and Cut Down, with Lethal Tempo being the keystone of choice.

What is Kai'Sa's secondary rune tree?

Kai'Sa's best secondary rune tree is Inspiration. The recommended Inspiration runes are Magical Footwear and Triple Tonic, which complement Kai'Sa's Precision primary tree.

What are alternative rune setups for Kai'Sa?

An alternative Kai'Sa rune setup uses Lethal Tempo from the Precision tree. This alternate build may be preferred in certain matchups or playstyles. Check the alternative rune page above for full details including win rate and pick rate.

How popular are Kai'Sa's runes?

Kai'Sa's top rune page has a 0.1% pick rate in patch 26.22. This indicates that 0.1% of Kai'Sa players use the Lethal Tempo setup with Precision and Inspiration trees.