
Vex vs Vayne is a decisive matchup in LoL patch 26.15. Vex wins with a 57.1% win rate (+14.3%) over Vayne based on 7 games. Vex holds the advantage in both the early and late game. Below you'll find the best Vex build, runes, laning stats, and strategies for the Vex vs Vayne matchup.
Use the dropdown to select an opponent and see a detailed breakdown of how Vex performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

The Vex vs Vayne matchup is a decisive matchup in League of Legends ranked play. Based on 7 recent matches analyzed, Vex wins with a 57.1% win rate compared to Vayne's 42.9%, giving Vex a 14.3 percentage point advantage. Vex dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Vayne players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Vex leads by 0.8s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Vex players can confidently pick into Vayne and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Vayne away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Vex is favored during the laning phase against Vayne, winning 4 out of 5 key stat categories. Vex holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.
Spellslinger's Shoes is the optimal boots choice against Vayne, providing the mobility and stats Vex needs most in this matchup. The top-performing core items for Vex against Vayne are Luden's Echo, Shadowflame and Zhonya's Hourglass. This combination gives Vex an effective balance of damage, survivability, and utility for the matchup. This build achieves a solid 50.0% win rate across 2 games, proving it to be a reliable item path when facing Vayne. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Vex vs Vayne matchup.
Vex dominates the early game (first 15 minutes) with a commanding 100.0% win rate — a 100.0 percentage point lead over Vayne. This lopsided early game means Vex can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Late game (25+ minutes) is equally balanced, with Vex at 50.0% win rate — only 0.0 points ahead of Vayne. Team fight execution and macro play determine the winner at this stage, not champion matchup advantage.
Vex holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Vayne players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.
Running Domination primary with Sorcery secondary allows Vex to press their advantage against Vayne, amplifying the strengths that make this a favorable matchup.
Vex matchup data for League of Legends patch 26.15. The table below shows Vex's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vex build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 45.13% | 113 | 6.0 | 953 | 12,357 | 50.0% | 42.9% | |
| 56.36% | 110 | 5.5 | 1,080 | 12,115 | 53.3% | 58.5% | |
| 53.70% | 108 | 5.5 | 942 | 10,603 | 56.1% | 51.0% | |
| 57.45% | 94 | 5.9 | 981 | 12,780 | 47.2% | 63.8% | |
| 53.93% | 89 | 6.0 | 1,004 | 11,930 | 56.8% | 51.9% | |
| 48.31% | 89 | 5.9 | 950 | 12,058 | 44.4% | 50.9% | |
| 53.09% | 81 | 5.8 | 895 | 12,064 | 61.3% | 48.0% | |
| 48.15% | 81 | 5.7 | 984 | 11,661 | 53.9% | 42.9% | |
| 60.81% | 74 | 5.5 | 911 | 11,422 | 56.3% | 64.3% | |
| 34.29% | 70 | 5.8 | 898 | 11,787 | 38.7% | 30.8% | |
| 43.33% | 60 | 5.6 | 909 | 12,423 | 30.4% | 51.4% | |
| 60.78% | 51 | 5.9 | 991 | 12,278 | 72.0% | 50.0% | |
| 56.00% | 50 | 6.0 | 1,115 | 13,547 | 55.6% | 56.3% | |
| 46.94% | 49 | 5.7 | 827 | 11,415 | 54.5% | 40.7% | |
| 71.43% | 49 | 5.9 | 935 | 11,670 | 67.9% | 76.2% | |
| 50.00% | 46 | 6.0 | 882 | 12,637 | 47.4% | 51.9% | |
| 52.17% | 46 | 6.4 | 998 | 12,731 | 63.2% | 44.4% | |
| 60.47% | 43 | 5.3 | 849 | 11,752 | 57.1% | 62.1% | |
| 52.50% | 40 | 5.8 | 877 | 12,667 | 56.3% | 50.0% | |
| 47.50% | 40 | 6.4 | 1,045 | 12,051 | 42.1% | 52.4% | |
| 67.50% | 40 | 6.1 | 1,037 | 12,052 | 66.7% | 68.8% | |
| 36.36% | 33 | 5.3 | 801 | 11,929 | 44.4% | 33.3% | |
| 54.55% | 33 | 5.5 | 845 | 11,053 | 70.6% | 37.5% | |
| 34.38% | 32 | 6.0 | 922 | 12,551 | 20.0% | 40.9% | |
| 41.94% | 31 | 5.8 | 992 | 11,794 | 40.0% | 43.8% | |
| 60.00% | 30 | 5.7 | 823 | 10,777 | 68.8% | 50.0% | |
| 44.44% | 27 | 6.1 | 1,040 | 12,864 | 22.2% | 55.6% | |
| 52.17% | 23 | 5.9 | 992 | 11,376 | 63.6% | 41.7% | |
| 57.14% | 21 | 6.1 | 955 | 11,424 | 63.6% | 50.0% | |
| 57.14% | 21 | 6.2 | 1,012 | 12,939 | 66.7% | 50.0% | |
| 55.00% | 20 | 6.1 | 971 | 11,961 | 54.5% | 55.6% | |
| 45.00% | 20 | 5.8 | 1,042 | 12,139 | 42.9% | 46.1% | |
| 63.16% | 19 | 5.8 | 934 | 12,500 | 40.0% | 71.4% | |
| 47.06% | 17 | 2.9 | 911 | 11,606 | 80.0% | 33.3% | |
| 64.71% | 17 | 5.8 | 985 | 11,819 | 42.9% | 80.0% | |
| 68.75% | 16 | 5.8 | 937 | 11,740 | 88.9% | 42.9% | |
| 40.00% | 15 | 5.6 | 833 | 10,470 | 37.5% | 42.9% | |
| 46.67% | 15 | 5.7 | 1,112 | 11,496 | 60.0% | 40.0% | |
| 50.00% | 14 | 4.6 | 893 | 12,289 | 50.0% | 50.0% | |
| 50.00% | 14 | 6.0 | 869 | 11,350 | 33.3% | 62.5% | |
| 75.00% | 12 | 6.0 | 841 | 11,687 | 77.8% | 66.7% | |
| 66.67% | 12 | 5.7 | 878 | 11,116 | 83.3% | 50.0% | |
| 58.33% | 12 | 5.7 | 1,051 | 10,778 | 50.0% | 62.5% | |
| 60.00% | 10 | 5.9 | 811 | 11,413 | 75.0% | 50.0% | |
| 50.00% | 10 | 6.1 | 979 | 12,408 | 66.7% | 42.9% | |
| 55.56% | 9 | 4.8 | 685 | 10,930 | 50.0% | 60.0% | |
| 33.33% | 9 | 5.1 | 1,068 | 14,263 | 33.3% | 33.3% | |
| 55.56% | 9 | 5.3 | 841 | 11,806 | 33.3% | 66.7% | |
| 62.50% | 8 | 5.8 | 892 | 12,936 | 100.0% | 57.1% | |
| 50.00% | 8 | 4.9 | 874 | 11,406 | 50.0% | 50.0% | |
| 62.50% | 8 | 6.4 | 1,162 | 15,022 | 50.0% | 75.0% | |
| 37.50% | 8 | 5.6 | 861 | 9,801 | 33.3% | 50.0% | |
| 57.14% | 7 | 6.7 | 969 | 14,517 | 100.0% | 50.0% | |
| 28.57% | 7 | 6.5 | 1,000 | 12,048 | 25.0% | 33.3% | |
| 42.86% | 7 | 5.2 | 795 | 10,067 | 50.0% | 33.3% | |
| 57.14% | 7 | 4.9 | 853 | 11,447 | 66.7% | 50.0% | |
| 42.86% | 7 | 6.5 | 1,003 | 9,566 | 42.9% | 0.0% | |
| 66.67% | 6 | 4.8 | 1,023 | 12,903 | 100.0% | 60.0% | |
| 33.33% | 6 | 5.6 | 983 | 11,112 | 20.0% | 100.0% | |
| 50.00% | 6 | 6.4 | 1,221 | 11,467 | 66.7% | 33.3% | |
| 50.00% | 6 | 4.9 | 1,096 | 13,631 | 100.0% | 40.0% | |
| 60.00% | 5 | 4.6 | 1,051 | 13,783 | 0.0% | 75.0% | |
| 40.00% | 5 | 6.3 | 849 | 7,160 | 50.0% | 0.0% | |
| 60.00% | 5 | 2.8 | 961 | 10,722 | 100.0% | 33.3% | |
| 60.00% | 5 | 5.4 | 840 | 11,161 | 100.0% | 50.0% | |
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Vex wins the Vex vs Vayne matchup with a 57.1% win rate compared to Vayne's 42.9%, a 14.3 percentage point difference. This data is based on 7 recent ranked games in patch 26.15.
In the early game, Vex has the advantage against Vayne with a 100.0% win rate versus 0.0%. Vex players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
In the late game, Vex takes over the Vex vs Vayne matchup with a 50.0% win rate compared to 50.0%. Vex scales better into team fights and objective contests after 25 minutes.
Vex wins the matchup against Vayne with a 57.1% win rate in League of Legends patch 26.15. The 14.3 percentage point advantage means Vex is significantly favored in this lane matchup based on 7 games analyzed.
The best Vex build against Vayne includes Luden's Echo, Shadowflame, Zhonya's Hourglass with Spellslinger's Shoes. This build achieves a 50.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.
The best Vex runes against Vayne use the Domination primary tree with Sorcery secondary. This rune setup achieves a 60.0% win rate in the Vex vs Vayne matchup. See the full rune breakdown in the matchup comparison above.
Yes, Vex has a favorable matchup against Vayne with a 57.1% win rate. Vex strongly counters Vayne in lane based on current patch 26.15 data.
When playing Vex against Vayne, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.
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