Vaynevs Vex
Vayne vs Vex is a decisive matchup in LoL patch 26.10. Vex wins with a 62.5% win rate (+25.0%) over Vayne based on 8 games. Vayne wins the early laning phase while Vex scales better into the late game. Below you'll find the best Vayne build, runes, laning stats, and strategies for the Vayne vs Vex matchup.
Vayne Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Vayne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Vex(37.5%)Who Wins the Vayne vs Vex Matchup?
Vayne vs Vex Matchup Summary
The Vayne vs Vex matchup is a decisive matchup in League of Legends ranked play. Based on 8 recent matches analyzed, Vex wins with a 62.5% win rate compared to Vayne's 37.5%, giving Vex a 25.0 percentage point advantage. Game phase dynamics play a critical role here: Vayne controls the early laning stage, but Vex outscales as the game goes longer. The matchup shifts dramatically depending on game length — Vayne needs to press advantages before Vex reaches their power spikes, while Vex should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Vex leads by 0.6s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Vex has a strong advantage in this matchup. Vayne players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Vex overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Vayne vs Vex Laning Phase Breakdown
Vex is favored during the laning phase against Vayne, winning 4 out of 5 key stat categories. Vex holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.
Best Vayne Build Against Vex
Swiftmarch is the optimal boots choice against Vex, providing the mobility and stats Vayne needs most in this matchup. The top-performing core items for Vayne against Vex are Hubris, Hexoptics C44 and Fiendhunter Bolts. This combination gives Vayne an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Vex. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Vayne vs Vex matchup.
Early Game vs Late Game
Vayne66.7%Vex33.3%Vayne20.0%Vex80.0%Vayne dominates the early game (first 15 minutes) with a commanding 66.7% win rate — a 33.3 percentage point lead over Vex. This lopsided early game means Vayne can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Vex is far superior in the late game (25+ minutes), boasting a 80.0% win rate — 60.0 points above Vayne. Extended games heavily favor Vex, whose kit and scaling make them a dominant force in team fights and objective control.
This matchup features a dramatic power shift: Vayne must aggressively press their early advantage and close out the game before Vex reaches their scaling breakpoints. If Vex survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.
Best Vayne Runes Against Vex
Domination
Inspiration
The Domination and Inspiration rune setup gives Vayne the best tools to compete against Vex in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.
Vayne matchup data for League of Legends patch 26.10. The table below shows Vayne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vayne build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 42.21% | 860 | 6.1 | 872 | 13,380 | 43.6% | 41.3% | |
| 48.35% | 668 | 6.0 | 788 | 12,821 | 46.9% | 49.5% | |
| 46.65% | 641 | 6.1 | 827 | 12,937 | 45.2% | 47.9% | |
| 53.54% | 536 | 6.2 | 841 | 13,288 | 52.5% | 54.4% | |
| 52.47% | 507 | 6.0 | 811 | 12,884 | 47.2% | 56.4% | |
| 48.71% | 505 | 5.7 | 770 | 12,213 | 46.5% | 50.5% | |
| 53.60% | 376 | 6.2 | 852 | 12,805 | 50.3% | 56.5% | |
| 50.98% | 306 | 6.3 | 892 | 13,184 | 46.1% | 55.2% | |
| 54.39% | 239 | 6.1 | 896 | 13,103 | 50.0% | 58.4% | |
| 52.75% | 218 | 6.0 | 826 | 12,717 | 49.5% | 55.3% | |
| 45.19% | 208 | 5.9 | 798 | 13,223 | 44.3% | 45.8% | |
| 49.50% | 200 | 6.1 | 827 | 13,582 | 46.8% | 51.2% | |
| 44.38% | 169 | 5.8 | 793 | 12,546 | 49.4% | 40.2% | |
| 46.71% | 167 | 6.4 | 951 | 12,236 | 47.8% | 46.0% | |
| 46.01% | 163 | 6.1 | 783 | 12,737 | 47.2% | 45.0% | |
| 47.50% | 160 | 6.0 | 817 | 12,747 | 46.1% | 48.8% | |
| 51.57% | 159 | 6.5 | 865 | 13,511 | 49.3% | 53.3% | |
| 43.67% | 158 | 5.8 | 656 | 11,114 | 37.7% | 48.3% | |
| 56.25% | 144 | 6.3 | 866 | 11,228 | 48.5% | 63.2% | |
| 58.96% | 134 | 5.9 | 931 | 11,611 | 60.0% | 58.2% | |
| 34.35% | 131 | 5.7 | 601 | 10,574 | 26.3% | 40.5% | |
| 48.03% | 127 | 5.9 | 810 | 12,758 | 32.8% | 60.9% | |
| 43.80% | 121 | 5.9 | 861 | 13,047 | 41.7% | 45.2% | |
| 46.61% | 118 | 6.2 | 803 | 12,418 | 44.6% | 49.1% | |
| 44.95% | 109 | 6.4 | 834 | 13,387 | 48.8% | 42.6% | |
| 56.07% | 107 | 5.9 | 933 | 11,833 | 63.3% | 50.0% | |
| 47.06% | 102 | 6.3 | 870 | 12,650 | 47.9% | 46.3% | |
| 56.18% | 89 | 6.2 | 725 | 10,514 | 51.1% | 61.4% | |
| 56.82% | 88 | 6.1 | 803 | 12,053 | 59.6% | 53.7% | |
| 45.68% | 81 | 5.7 | 903 | 11,091 | 48.7% | 42.9% | |
| 53.09% | 81 | 6.5 | 1,099 | 12,990 | 41.7% | 62.2% | |
| 46.84% | 79 | 6.2 | 1,298 | 12,010 | 40.6% | 51.1% | |
| 53.42% | 73 | 5.7 | 1,120 | 12,612 | 51.9% | 54.4% | |
| 52.94% | 68 | 5.9 | 807 | 11,301 | 56.3% | 50.0% | |
| 42.65% | 68 | 5.9 | 947 | 12,250 | 26.1% | 51.1% | |
| 55.88% | 68 | 6.8 | 874 | 11,940 | 55.9% | 55.9% | |
| 50.00% | 68 | 6.6 | 851 | 11,661 | 48.5% | 51.4% | |
| 41.18% | 68 | 6.4 | 953 | 12,133 | 57.1% | 30.0% | |
| 58.06% | 62 | 6.3 | 977 | 12,030 | 59.3% | 57.1% | |
| 47.46% | 59 | 6.2 | 989 | 11,887 | 48.0% | 47.1% | |
| 52.83% | 53 | 6.0 | 733 | 13,262 | 45.0% | 57.6% | |
| 56.60% | 53 | 5.8 | 801 | 12,189 | 54.5% | 58.1% | |
| 52.83% | 53 | 5.8 | 821 | 12,721 | 54.5% | 51.6% | |
| 58.49% | 53 | 6.2 | 936 | 12,238 | 57.1% | 59.4% | |
| 58.49% | 53 | 6.3 | 1,030 | 13,721 | 50.0% | 65.5% | |
| 49.02% | 51 | 5.9 | 874 | 10,987 | 44.0% | 53.9% | |
| 50.00% | 50 | 6.2 | 867 | 12,630 | 40.0% | 60.0% | |
| 63.27% | 49 | 6.4 | 804 | 12,522 | 80.0% | 51.7% | |
| 58.33% | 48 | 6.2 | 884 | 11,914 | 56.5% | 60.0% | |
| 42.55% | 47 | 6.4 | 850 | 12,414 | 50.0% | 36.0% | |
| 53.33% | 45 | 5.6 | 800 | 11,861 | 45.0% | 60.0% | |
| 54.55% | 44 | 6.0 | 909 | 13,606 | 57.1% | 53.3% | |
| 55.81% | 43 | 6.4 | 922 | 13,202 | 63.2% | 50.0% | |
| 37.21% | 43 | 5.9 | 783 | 12,220 | 50.0% | 29.6% | |
| 47.62% | 42 | 6.1 | 904 | 13,379 | 35.0% | 59.1% | |
| 51.22% | 41 | 6.3 | 1,025 | 12,349 | 41.2% | 58.3% | |
| 45.00% | 40 | 5.3 | 848 | 12,889 | 50.0% | 42.3% | |
| 50.00% | 40 | 6.5 | 842 | 12,057 | 52.6% | 47.6% | |
| 51.28% | 39 | 6.0 | 908 | 11,110 | 60.9% | 37.5% | |
| 50.00% | 38 | 6.3 | 888 | 13,077 | 40.0% | 53.6% | |
| 63.16% | 38 | 4.1 | 867 | 11,739 | 59.1% | 68.8% | |
| 37.84% | 37 | 5.4 | 745 | 10,304 | 21.1% | 55.6% | |
| 58.33% | 36 | 6.5 | 956 | 11,031 | 47.6% | 73.3% | |
| 51.43% | 35 | 6.5 | 919 | 11,948 | 61.5% | 45.5% | |
| 45.45% | 33 | 5.5 | 823 | 12,066 | 25.0% | 57.1% | |
| 75.76% | 33 | 5.7 | 742 | 11,321 | 82.3% | 68.8% | |
| 50.00% | 30 | 6.1 | 1,027 | 12,921 | 58.3% | 44.4% | |
| 50.00% | 28 | 6.0 | 806 | 12,719 | 33.3% | 57.9% | |
| 60.71% | 28 | 6.1 | 765 | 11,907 | 64.3% | 57.1% | |
| 51.85% | 27 | 5.2 | 812 | 11,409 | 28.6% | 76.9% | |
| 40.74% | 27 | 6.2 | 683 | 9,797 | 46.7% | 33.3% | |
| 48.15% | 27 | 6.3 | 774 | 11,833 | 50.0% | 46.7% | |
| 46.15% | 26 | 5.9 | 727 | 11,522 | 50.0% | 42.9% | |
| 53.85% | 26 | 6.4 | 896 | 13,089 | 41.7% | 64.3% | |
| 65.38% | 26 | 6.4 | 888 | 12,576 | 60.0% | 68.8% | |
| 46.15% | 26 | 6.1 | 811 | 12,732 | 33.3% | 57.1% | |
| 52.00% | 25 | 5.5 | 819 | 13,406 | 57.1% | 50.0% | |
| 20.00% | 25 | 5.9 | 677 | 11,114 | 7.1% | 36.4% | |
| 58.33% | 24 | 6.2 | 854 | 13,429 | 54.5% | 61.5% | |
| 37.50% | 24 | 5.0 | 626 | 8,646 | 25.0% | 62.5% | |
| 47.83% | 23 | 6.2 | 875 | 13,728 | 50.0% | 46.1% | |
| 43.48% | 23 | 6.5 | 927 | 11,037 | 40.0% | 46.1% | |
| 63.64% | 22 | 3.5 | 952 | 12,743 | 69.2% | 55.6% | |
| 42.86% | 21 | 5.0 | 672 | 11,616 | 45.5% | 40.0% | |
| 38.10% | 21 | 6.3 | 999 | 10,857 | 36.4% | 40.0% | |
| 33.33% | 21 | 6.0 | 947 | 11,415 | 40.0% | 27.3% | |
| 35.00% | 20 | 6.2 | 726 | 12,173 | 44.4% | 27.3% | |
| 30.00% | 20 | 6.0 | 748 | 12,018 | 28.6% | 30.8% | |
| 63.16% | 19 | 4.6 | 1,064 | 12,921 | 54.5% | 75.0% | |
| 50.00% | 18 | 6.7 | 924 | 11,793 | 55.6% | 44.4% | |
| 44.44% | 18 | 6.5 | 1,011 | 12,353 | 33.3% | 50.0% | |
| 37.50% | 16 | 5.3 | 670 | 9,773 | 18.2% | 80.0% | |
| 50.00% | 16 | 6.7 | 993 | 14,038 | 71.4% | 33.3% | |
| 50.00% | 16 | 6.3 | 924 | 12,955 | 80.0% | 36.4% | |
| 50.00% | 16 | 5.7 | 1,008 | 13,676 | 50.0% | 50.0% | |
| 60.00% | 15 | 5.8 | 984 | 13,362 | 50.0% | 63.6% | |
| 60.00% | 15 | 6.0 | 953 | 14,670 | 33.3% | 66.7% | |
| 64.29% | 14 | 5.1 | 1,014 | 13,683 | 50.0% | 70.0% | |
| 38.46% | 13 | 3.6 | 779 | 11,679 | 33.3% | 42.9% | |
| 46.15% | 13 | 2.9 | 721 | 13,246 | 20.0% | 62.5% | |
| 50.00% | 12 | 6.3 | 721 | 11,962 | 50.0% | 50.0% | |
| 66.67% | 12 | 5.9 | 1,033 | 11,796 | 71.4% | 60.0% | |
| 72.73% | 11 | 5.6 | 900 | 12,586 | 60.0% | 83.3% | |
| 54.55% | 11 | 5.1 | 991 | 14,168 | 66.7% | 50.0% | |
| 27.27% | 11 | 3.3 | 618 | 11,941 | 50.0% | 14.3% | |
| 36.36% | 11 | 6.4 | 775 | 9,363 | 37.5% | 33.3% | |
| 60.00% | 10 | 3.5 | 950 | 11,451 | 50.0% | 75.0% | |
| 70.00% | 10 | 3.5 | 984 | 14,774 | 50.0% | 75.0% | |
| 70.00% | 10 | 2.2 | 881 | 12,712 | 50.0% | 83.3% | |
| 30.00% | 10 | 3.0 | 751 | 12,482 | 20.0% | 40.0% | |
| 50.00% | 10 | 4.9 | 749 | 14,596 | 0.0% | 55.6% | |
| 40.00% | 10 | 3.2 | 887 | 13,613 | 66.7% | 28.6% | |
| 33.33% | 9 | 6.8 | 813 | 13,438 | 25.0% | 40.0% | |
| 55.56% | 9 | 6.5 | 1,081 | 14,802 | 100.0% | 33.3% | |
| 55.56% | 9 | 1.2 | 710 | 11,670 | 60.0% | 50.0% | |
| 44.44% | 9 | 6.9 | 996 | 10,362 | 50.0% | 40.0% | |
| 44.44% | 9 | 5.6 | 891 | 10,790 | 20.0% | 75.0% | |
| 37.50% | 8 | 5.8 | 644 | 11,385 | 66.7% | 20.0% | |
| 62.50% | 8 | 4.0 | 1,293 | 13,786 | 60.0% | 66.7% | |
| 75.00% | 8 | 3.1 | 889 | 12,617 | 75.0% | 75.0% | |
| 71.43% | 7 | 3.0 | 532 | 7,751 | 50.0% | 100.0% | |
| 57.14% | 7 | 5.3 | 911 | 12,799 | 33.3% | 75.0% | |
| 28.57% | 7 | 6.5 | 816 | 9,928 | 25.0% | 33.3% | |
| 71.43% | 7 | 5.9 | 678 | 11,941 | 100.0% | 50.0% | |
| 50.00% | 6 | 4.3 | 996 | 14,686 | 50.0% | 50.0% | |
| 66.67% | 6 | 6.5 | 1,069 | 14,100 | 66.7% | 66.7% | |
| 60.00% | 5 | 6.3 | 1,000 | 16,366 | 100.0% | 50.0% | |
| 0.00% | 5 | 6.7 | 547 | 8,027 | 0.0% | 0.0% | |
| 80.00% | 5 | 2.4 | 1,036 | 14,100 | 100.0% | 75.0% | |
| 40.00% | 5 | 2.4 | 924 | 16,141 | 0.0% | 40.0% | |
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Vayne vs Vex - Frequently Asked Questions
How does Vayne do against Vex in League of Legends?
Vex wins the Vayne vs Vex matchup with a 62.5% win rate compared to Vayne's 37.5%, a 25.0 percentage point difference. This data is based on 8 recent ranked games in patch 26.10.
How does Vayne do against Vex in the early game?
In the early game, Vayne has the advantage against Vex with a 66.7% win rate versus 33.3%. Vayne players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Vayne do against Vex in the late game?
In the late game, Vex takes over the Vayne vs Vex matchup with a 80.0% win rate compared to 20.0%. Vex scales better into team fights and objective contests after 25 minutes.
Who wins the Vayne vs Vex matchup?
Vex wins the matchup against Vayne with a 62.5% win rate in League of Legends patch 26.10. The 25.0 percentage point advantage means Vex is significantly favored in this lane matchup based on 8 games analyzed.
What is the best Vayne build against Vex?
The best Vayne build against Vex includes Hubris, Hexoptics C44, Fiendhunter Bolts with Swiftmarch. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.
What are the best Vayne runes against Vex?
The best Vayne runes against Vex use the Domination primary tree with Inspiration secondary. This rune setup achieves a 100.0% win rate in the Vayne vs Vex matchup. See the full rune breakdown in the matchup comparison above.
Does Vayne counter Vex?
No, Vayne struggles against Vex with only a 37.5% win rate. Vex has the advantage in this matchup. Vayne players should focus on safe farming and avoiding extended trades to minimize Vex's lead.
How do I play Vayne against Vex?
When playing Vayne against Vex, play cautiously and avoid Vex's power spikes. Look for jungle assistance and team-dependent plays since Vex has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.