Yasuo - League of Legends Champion
Win Rate
49.7%
Pick Rate
7.5%

Yasuovs Karthus

CFighterAssassin
Patch26.14
Matches226,800
LaneAll Lanes
TierAll Tiers
Last UpdatedJul 21, 2026
MethodologyData Methodology

Yasuo vs Karthus is a decisive matchup in LoL patch 26.14. Yasuo wins with a 66.7% win rate (+33.3%) over Karthus based on 6 games. Yasuo wins the early laning phase while Karthus scales better into the late game. Below you'll find the best Yasuo build, runes, laning stats, and strategies for the Yasuo vs Karthus matchup.

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Yasuo Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Yasuo performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Yasuo - 66.7% win rate in this matchup
Yasuo
66.7% WR
VS
Karthus vs Yasuo matchup - 33.3% win rate
Karthus
33.3% WR

Who Wins the Yasuo vs Karthus Matchup?

Yasuo wins the Yasuo vs Karthus matchup
Winner
Yasuo
Matches: 6
66.7%
Win Rate
33.3%
6.6
CS / min
5.6
995
DMG / min
1,013
12,922
Gold / game
11,523
382
Heal / min
126
1,103
DMG Mitigated / min
407
1.0
CC / min
0.6
100.0%
Early Game WR
0.0%
0.0%
Late Game WR
100.0%

Yasuo vs Karthus Matchup Summary

The Yasuo vs Karthus matchup is a decisive matchup in League of Legends ranked play. Based on 6 recent matches analyzed, Yasuo wins with a 66.7% win rate compared to Karthus's 33.3%, giving Yasuo a 33.3 percentage point advantage. Game phase dynamics play a critical role here: Yasuo controls the early laning stage, but Karthus outscales as the game goes longer. The matchup shifts dramatically depending on game length — Yasuo needs to press advantages before Karthus reaches their power spikes, while Karthus should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in sustain, where Yasuo leads by 951 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Yasuo players can confidently pick into Karthus and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Karthus away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Yasuo vs Karthus Laning Phase Breakdown

Yasuo wins the laning phase against Karthus in League of Legends

Yasuo is favored during the laning phase against Karthus, winning 4 out of 5 key stat categories. Yasuo holds advantages in farming, gold income, crowd control and sustain, making them the stronger laner in this matchup.

Farming
6.6Yasuo
5.6Karthus
Yasuo significantly out-farms Karthus by 0.9 CS per minute, accumulating an estimated 14 CS lead by mid game. This substantial farming gap gives Yasuo a major gold advantage and earlier item completions. Karthus players should prioritize wave management techniques like freezing near tower and using abilities efficiently to minimize the deficit.
Damage
995Yasuo
1,013Karthus
Damage output is virtually even between Yasuo and Karthus, with only 18 DMG/min separating them. Fights in this matchup are decided more by ability timing and positioning than raw damage numbers, making mechanical skill the deciding factor in trades.
Economy
12,922Yasuo
11,523Karthus
Yasuo generates a commanding 1,399 more gold per game than Karthus. This substantial economic advantage means Yasuo consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Karthus should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
1.0Yasuo
0.6Karthus
Yasuo provides 0.4 seconds more crowd control per minute than Karthus, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Yasuo coordinate with their jungler and control the pace of skirmishes.
Sustain
1,485Yasuo
533Karthus
Yasuo vastly out-sustains Karthus, healing and mitigating 951 more damage per minute. This massive durability gap means Yasuo can absorb significant punishment and remain in lane while Karthus is forced to recall. Building grievous wounds early is essential for Karthus, and focusing on burst trade patterns rather than sustained fights is critical.

Best Yasuo Build Against Karthus

Gunmetal Greaves is the optimal boots choice against Karthus, providing the mobility and stats Yasuo needs most in this matchup. The top-performing core items for Yasuo against Karthus are Immortal Shieldbow, Blade of The Ruined King and Infinity Edge. This combination gives Yasuo an effective balance of damage, survivability, and utility for the matchup. This build achieves a solid 50.0% win rate across 2 games, proving it to be a reliable item path when facing Karthus. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Yasuo vs Karthus matchup.

Early Game vs Late Game

Early Game
Yasuo
100.0%
+100.0% advantage
Yasuo early game win rateYasuo100.0%
Karthus early game win rateKarthus0.0%
Late Game
Karthus
100.0%
+100.0% advantage
Yasuo late game win rateYasuo0.0%
Karthus late game win rateKarthus100.0%

Yasuo dominates the early game (first 15 minutes) with a commanding 100.0% win rate — a 100.0 percentage point lead over Karthus. This lopsided early game means Yasuo can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Karthus is far superior in the late game (25+ minutes), boasting a 100.0% win rate — 100.0 points above Yasuo. Extended games heavily favor Karthus, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Yasuo must aggressively press their early advantage and close out the game before Karthus reaches their scaling breakpoints. If Karthus survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Yasuo Runes Against Karthus

Precision rune tree - Yasuo primary runes vs KarthusPrecision
Lethal Tempo - best Yasuo rune vs KarthusAbsorb Life - best Yasuo rune vs KarthusLegend: Alacrity - best Yasuo rune vs KarthusLast Stand - best Yasuo rune vs Karthus
Resolve rune tree - Yasuo secondary runes vs KarthusResolve
Overgrowth - best Yasuo rune vs KarthusSecond Wind - best Yasuo rune vs Karthus
33.3% WR

Running Precision primary with Resolve secondary allows Yasuo to press their advantage against Karthus, amplifying the strengths that make this a favorable matchup.


Yasuo matchup data for League of Legends patch 26.14. The table below shows Yasuo's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Yasuo build, runes, laning stats, and early vs late game analysis for that specific matchup.

Yasuo matchup win rates and stats in League of Legends patch 26.14
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
52.03%1486.888611,44745.6%57.5%
48.87%1336.884312,04241.1%54.5%
43.75%1127.078111,49742.9%44.4%
45.37%1086.897611,60351.9%39.3%
53.40%1037.077512,92154.0%53.0%
47.87%946.983911,90553.9%43.6%
58.62%876.886612,55053.9%60.7%
46.34%826.988412,20441.2%50.0%
43.21%816.978211,83045.2%42.0%
53.85%787.288211,63247.4%60.0%
55.93%597.075211,77650.0%62.1%
51.79%567.186511,07453.6%50.0%
42.59%546.875812,04245.8%40.0%
48.15%547.086711,23652.2%45.2%
56.60%536.788511,47350.0%62.1%
36.54%526.894711,34740.9%33.3%
49.02%517.087612,77147.8%50.0%
56.86%516.781311,73761.1%54.5%
43.75%486.973112,25133.3%50.0%
48.89%456.979610,40839.1%59.1%
34.88%436.769711,74138.9%32.0%
57.14%427.175610,65570.6%48.0%
56.10%417.382012,12456.3%56.0%
51.22%416.777411,47560.0%42.9%
35.00%406.877111,69433.3%36.4%
41.67%366.876910,41950.0%36.4%
51.43%357.082812,32360.0%45.0%
44.12%347.575510,52927.8%62.5%
50.00%346.874411,21946.7%52.6%
50.00%346.377613,74636.4%56.5%
48.48%336.784011,30138.5%55.0%
51.52%336.583012,13969.2%40.0%
48.48%337.490912,19252.9%43.8%
46.88%327.079910,77646.7%47.1%
51.72%296.589513,40975.0%35.3%
51.72%297.295211,85657.1%46.7%
65.52%296.983013,67678.6%53.3%
27.59%297.070912,8630.0%38.1%
46.43%287.389812,50437.5%50.0%
32.14%287.17149,38515.4%46.7%
50.00%286.489210,42157.1%42.9%
51.85%277.274312,24536.4%62.5%
38.46%267.078010,21830.8%46.1%
65.38%267.194514,71760.0%66.7%
57.69%267.376811,86161.5%53.9%
50.00%267.080912,91346.1%53.9%
52.00%256.776411,76640.0%60.0%
40.00%257.287512,84455.6%31.3%
64.00%257.178012,50444.4%75.0%
52.17%237.179110,44554.5%50.0%
60.87%236.584812,84962.5%60.0%
56.52%236.580410,62661.5%50.0%
72.73%227.191213,73788.9%61.5%
50.00%227.273112,13950.0%50.0%
54.55%226.77589,85333.3%69.2%
50.00%226.981011,56044.4%53.9%
36.36%226.889411,51333.3%38.5%
45.45%226.890010,67330.8%66.7%
61.90%217.084310,58780.0%45.5%
60.00%207.41,00313,48375.0%50.0%
65.00%206.91,09111,89270.0%60.0%
52.63%197.083714,28862.5%45.5%
52.63%196.38359,28855.6%50.0%
68.42%197.394812,94157.1%75.0%
55.56%187.897513,42450.0%60.0%
50.00%187.282211,44855.6%44.4%
27.78%186.46049,44625.0%33.3%
58.82%176.983710,85944.4%75.0%
47.06%176.579911,06883.3%27.3%
50.00%167.397213,70085.7%22.2%
40.00%157.181011,47440.0%40.0%
50.00%146.51,00215,17366.7%45.5%
71.43%147.382112,23185.7%57.1%
35.71%147.765312,10866.7%12.5%
71.43%147.11,00912,54180.0%66.7%
57.14%147.085314,42640.0%66.7%
57.14%147.91,24812,39280.0%44.4%
61.54%136.271410,35955.6%75.0%
46.15%137.18649,39440.0%66.7%
46.15%136.37558,11540.0%50.0%
41.67%127.884813,28640.0%42.9%
50.00%126.589112,42762.5%25.0%
41.67%126.892612,7160.0%50.0%
41.67%127.09349,39860.0%28.6%
45.45%117.095813,72440.0%50.0%
54.55%117.11,14011,50150.0%57.1%
63.64%117.76709,20475.0%33.3%
72.73%116.574514,8680.0%80.0%
40.00%107.175214,6640.0%44.4%
70.00%107.094013,30650.0%83.3%
50.00%107.168411,34042.9%66.7%
40.00%108.188413,29033.3%50.0%
50.00%106.774112,33033.3%57.1%
33.33%95.790413,00666.7%16.7%
22.22%97.669612,595100.0%0.0%
22.22%96.786110,1530.0%33.3%
55.56%96.81,09510,86440.0%75.0%
55.56%96.88278,28950.0%66.7%
37.50%87.684610,33360.0%0.0%
37.50%86.077711,7060.0%75.0%
87.50%87.072710,155100.0%80.0%
71.43%76.71,13613,55375.0%66.7%
42.86%76.166612,10833.3%50.0%
57.14%77.985714,60833.3%75.0%
57.14%77.585814,11250.0%60.0%
28.57%76.893714,2920.0%28.6%
28.57%77.288711,36333.3%25.0%
14.29%76.746010,31725.0%0.0%
50.00%66.775510,63050.0%50.0%
33.33%65.86639,91825.0%50.0%
66.67%66.699512,922100.0%0.0%
66.67%66.776112,31150.0%75.0%
20.00%57.286313,78533.3%0.0%
60.00%55.362212,949100.0%33.3%
60.00%56.01,01014,386100.0%33.3%

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Yasuo vs Karthus - Frequently Asked Questions

How does Yasuo do against Karthus in League of Legends?

Yasuo wins the Yasuo vs Karthus matchup with a 66.7% win rate compared to Karthus's 33.3%, a 33.3 percentage point difference. This data is based on 6 recent ranked games in patch 26.14.

How does Yasuo do against Karthus in the early game?

In the early game, Yasuo has the advantage against Karthus with a 100.0% win rate versus 0.0%. Yasuo players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Yasuo do against Karthus in the late game?

In the late game, Karthus takes over the Yasuo vs Karthus matchup with a 100.0% win rate compared to 0.0%. Karthus scales better into team fights and objective contests after 25 minutes.

Who wins the Yasuo vs Karthus matchup?

Yasuo wins the matchup against Karthus with a 66.7% win rate in League of Legends patch 26.14. The 33.3 percentage point advantage means Yasuo is significantly favored in this lane matchup based on 6 games analyzed.

What is the best Yasuo build against Karthus?

The best Yasuo build against Karthus includes Immortal Shieldbow, Blade of The Ruined King, Infinity Edge with Gunmetal Greaves. This build achieves a 50.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Yasuo runes against Karthus?

The best Yasuo runes against Karthus use the Precision primary tree with Resolve secondary. This rune setup achieves a 33.3% win rate in the Yasuo vs Karthus matchup. See the full rune breakdown in the matchup comparison above.

Does Yasuo counter Karthus?

Yes, Yasuo has a favorable matchup against Karthus with a 66.7% win rate. Yasuo strongly counters Karthus in lane based on current patch 26.14 data.

How do I play Yasuo against Karthus?

When playing Yasuo against Karthus, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.