Karthus - League of Legends Champion
Win Rate
52.9%
Pick Rate
0.9%

Karthusvs Yasuo

SMage
Patch26.14
Matches226,800
LaneAll Lanes
TierAll Tiers
Last UpdatedJul 21, 2026
MethodologyData Methodology

Karthus vs Yasuo is a decisive matchup in LoL patch 26.14. Yasuo wins with a 66.7% win rate (+33.3%) over Karthus based on 6 games. Yasuo wins the early laning phase while Karthus scales better into the late game. Below you'll find the best Karthus build, runes, laning stats, and strategies for the Karthus vs Yasuo matchup.

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Karthus Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Karthus performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Karthus - 33.3% win rate in this matchup
Karthus
33.3% WR
VS
Yasuo vs Karthus matchup - 66.7% win rate
Yasuo
66.7% WR

Who Wins the Karthus vs Yasuo Matchup?

Yasuo wins the Karthus vs Yasuo matchup
Winner
Yasuo
Matches: 6
33.3%
Win Rate
66.7%
5.6
CS / min
6.6
1,013
DMG / min
995
11,523
Gold / game
12,922
126
Heal / min
382
407
DMG Mitigated / min
1,103
0.6
CC / min
1.0
0.0%
Early Game WR
100.0%
100.0%
Late Game WR
0.0%

Karthus vs Yasuo Matchup Summary

The Karthus vs Yasuo matchup is a decisive matchup in League of Legends ranked play. Based on 6 recent matches analyzed, Yasuo wins with a 66.7% win rate compared to Karthus's 33.3%, giving Yasuo a 33.3 percentage point advantage. Game phase dynamics play a critical role here: Yasuo controls the early laning stage, but Karthus outscales as the game goes longer. The matchup shifts dramatically depending on game length — Yasuo needs to press advantages before Karthus reaches their power spikes, while Karthus should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in sustain, where Yasuo leads by 951 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Yasuo has a strong advantage in this matchup. Karthus players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Yasuo overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Karthus vs Yasuo Laning Phase Breakdown

Yasuo wins the laning phase against Karthus in League of Legends

Yasuo is favored during the laning phase against Karthus, winning 4 out of 5 key stat categories. Yasuo holds advantages in farming, gold income, crowd control and sustain, making them the stronger laner in this matchup.

Farming
5.6Karthus
6.6Yasuo
Yasuo significantly out-farms Karthus by 0.9 CS per minute, accumulating an estimated 14 CS lead by mid game. This substantial farming gap gives Yasuo a major gold advantage and earlier item completions. Karthus players should prioritize wave management techniques like freezing near tower and using abilities efficiently to minimize the deficit.
Damage
1,013Karthus
995Yasuo
Damage output is virtually even between Karthus and Yasuo, with only 18 DMG/min separating them. Fights in this matchup are decided more by ability timing and positioning than raw damage numbers, making mechanical skill the deciding factor in trades.
Economy
11,523Karthus
12,922Yasuo
Yasuo generates a commanding 1,399 more gold per game than Karthus. This substantial economic advantage means Yasuo consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Karthus should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.6Karthus
1.0Yasuo
Yasuo provides 0.4 seconds more crowd control per minute than Karthus, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Yasuo coordinate with their jungler and control the pace of skirmishes.
Sustain
533Karthus
1,485Yasuo
Yasuo vastly out-sustains Karthus, healing and mitigating 951 more damage per minute. This massive durability gap means Yasuo can absorb significant punishment and remain in lane while Karthus is forced to recall. Building grievous wounds early is essential for Karthus, and focusing on burst trade patterns rather than sustained fights is critical.

Best Karthus Build Against Yasuo

Spellslinger's Shoes is the optimal boots choice against Yasuo, providing the mobility and stats Karthus needs most in this matchup. The top-performing core items for Karthus against Yasuo are Malignance, Rabadon's Deathcap and Blackfire Torch. This combination gives Karthus an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Karthus vs Yasuo matchup.

Early Game vs Late Game

Early Game
Yasuo
100.0%
+100.0% advantage
Karthus early game win rateKarthus0.0%
Yasuo early game win rateYasuo100.0%
Late Game
Karthus
100.0%
+100.0% advantage
Karthus late game win rateKarthus100.0%
Yasuo late game win rateYasuo0.0%

Yasuo dominates the early game (first 15 minutes) with a commanding 100.0% win rate — a 100.0 percentage point lead over Karthus. This lopsided early game means Yasuo can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Karthus is far superior in the late game (25+ minutes), boasting a 100.0% win rate — 100.0 points above Yasuo. Extended games heavily favor Karthus, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Yasuo must aggressively press their early advantage and close out the game before Karthus reaches their scaling breakpoints. If Karthus survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Karthus Runes Against Yasuo

Domination rune tree - Karthus primary runes vs YasuoDomination
Dark Harvest - best Karthus rune vs YasuoCheap Shot - best Karthus rune vs YasuoGrisly Mementos - best Karthus rune vs YasuoTreasure Hunter - best Karthus rune vs Yasuo
Precision rune tree - Karthus secondary runes vs YasuoPrecision
Coup de Grace - best Karthus rune vs YasuoPresence of Mind - best Karthus rune vs Yasuo
100.0% WR

The Domination and Precision rune setup gives Karthus the best tools to compete against Yasuo in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Karthus matchup data for League of Legends patch 26.14. The table below shows Karthus's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Karthus build, runes, laning stats, and early vs late game analysis for that specific matchup.

Karthus matchup win rates and stats in League of Legends patch 26.14
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
64.71%171.61,30714,66766.7%64.3%
61.54%131.41,26816,483100.0%54.5%
38.46%131.71,13714,45550.0%33.3%
53.85%131.289010,32966.7%42.9%
66.67%127.01,13812,77283.3%50.0%
50.00%126.81,06013,5260.0%66.7%
66.67%121.21,22315,65033.3%77.8%
54.55%111.493212,47820.0%83.3%
54.55%111.31,25216,58775.0%42.9%
30.00%101.21,05811,5090.0%60.0%
77.78%96.91,58016,28933.3%100.0%
77.78%91.11,46516,15150.0%85.7%
50.00%81.41,36413,21550.0%50.0%
62.50%82.11,29411,38950.0%75.0%
75.00%81.71,19514,4940.0%85.7%
62.50%80.91,03211,64366.7%60.0%
0.00%81.29159,7700.0%0.0%
100.00%81.31,14611,386100.0%100.0%
71.43%75.91,21011,767100.0%60.0%
42.86%73.81,20014,23566.7%25.0%
50.00%61.81,15115,1510.0%60.0%
50.00%66.81,05414,8930.0%60.0%
33.33%65.61,01311,5230.0%100.0%
66.67%66.31,18714,6750.0%80.0%
40.00%50.91,14013,258100.0%25.0%
60.00%56.31,26410,41750.0%66.7%
40.00%50.91,00613,487100.0%25.0%
20.00%55.393411,78633.3%0.0%
40.00%51.21,37916,148100.0%25.0%
20.00%54.39793,1650.0%100.0%
60.00%51.31,04614,377100.0%50.0%
25.00%41.41,38413,8210.0%33.3%
25.00%42.31,12113,8860.0%33.3%
100.00%21.51,21814,599100.0%100.0%

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Karthus vs Yasuo - Frequently Asked Questions

How does Karthus do against Yasuo in League of Legends?

Yasuo wins the Karthus vs Yasuo matchup with a 66.7% win rate compared to Karthus's 33.3%, a 33.3 percentage point difference. This data is based on 6 recent ranked games in patch 26.14.

How does Karthus do against Yasuo in the early game?

In the early game, Yasuo has the advantage against Karthus with a 100.0% win rate versus 0.0%. Yasuo players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Karthus do against Yasuo in the late game?

In the late game, Karthus takes over the Karthus vs Yasuo matchup with a 100.0% win rate compared to 0.0%. Karthus scales better into team fights and objective contests after 25 minutes.

Who wins the Karthus vs Yasuo matchup?

Yasuo wins the matchup against Karthus with a 66.7% win rate in League of Legends patch 26.14. The 33.3 percentage point advantage means Yasuo is significantly favored in this lane matchup based on 6 games analyzed.

What is the best Karthus build against Yasuo?

The best Karthus build against Yasuo includes Malignance, Rabadon's Deathcap, Blackfire Torch with Spellslinger's Shoes. Check the matchup breakdown above for the full item path and build order.

What are the best Karthus runes against Yasuo?

The best Karthus runes against Yasuo use the Domination primary tree with Precision secondary. This rune setup achieves a 100.0% win rate in the Karthus vs Yasuo matchup. See the full rune breakdown in the matchup comparison above.

Does Karthus counter Yasuo?

No, Karthus struggles against Yasuo with only a 33.3% win rate. Yasuo has the advantage in this matchup. Karthus players should focus on safe farming and avoiding extended trades to minimize Yasuo's lead.

How do I play Karthus against Yasuo?

When playing Karthus against Yasuo, play cautiously and avoid Yasuo's power spikes. Focus on safe farming — you outscale Yasuo in the late game. Use the matchup-specific build and runes above to optimize your chances.