- Win Rate
- 50.3%
- Pick Rate
- 3.5%
- Ban Rate
- 19.6%
Zed Mid Runes: Keystone & Shards
- Patch
- 26.20
- Games
- 4,525
- Lane
- Mid
- Tier
- All Tiers
- Last Updated
- Oct 12, 2026 UTC
- Methodology
- Data Methodology
- Author
- Dakota Chinnick
Best Mid Zed runes for LoL Patch 26.20 - First Strike from the Inspiration tree with Precision secondary (63.8% WR, 2.3% pick rate). Zed's optimal primary runes are First Strike, Cash Back, Triple Tonic, Jack Of All Trades. Secondary tree: Legend: Haste, Cut Down.
Primary Tree
Inspiration
First StrikeAttacks or abilities against an enemy champion within 0.25s of entering champion combat grant 10 gold and First Strike for 3 seconds, causing you to deal
Cooldown:
Cash BackGet 7.5% Gold back when you purchase Legendary Items.
Triple TonicUpon reaching level 3, gain an Elixir of Avarice.
Upon reaching level 6, gain an Elixir of Force.
Upon reaching level 9, gain an Elixir of Skill.
Jack Of All TradesFor each different stat gained from items, gain one Jack stack. Each stack grants you
Gain 8 or 20 bonus
Legend: HasteGain 1.5 basic ability haste for every Legend stack (
Earn progress toward Legend stacks for every champion takedown, epic monster takedown, large monster kill, and minion kill.
Cut DownDeal 8% more damage to champions who have more than 60% health.
Primary Tree
InspirationFirst StrikeAttacks or abilities against an enemy champion within 0.25s of entering champion combat grant 10 gold and First Strike for 3 seconds, causing you to deal
Cooldown:
Cash BackGet 7.5% Gold back when you purchase Legendary Items.
Triple TonicUpon reaching level 3, gain an Elixir of Avarice.
Upon reaching level 6, gain an Elixir of Force.
Upon reaching level 9, gain an Elixir of Skill.
Jack Of All TradesFor each different stat gained from items, gain one Jack stack. Each stack grants you
Gain 8 or 20 bonus
Cut DownDeal 8% more damage to champions who have more than 60% health.
Legend: HasteGain 1.5 basic ability haste for every Legend stack (
Earn progress toward Legend stacks for every champion takedown, epic monster takedown, large monster kill, and minion kill.
Every Zed Mid Keystone and Secondary Tree (Patch 26.20)
4,371 gamesZed Mid runs First Strike in 56% of games, with a 52.0% win rate. Precision is the usual secondary tree (66%). Standard stat shards: Adaptive Force (offense), Adaptive Force (flex), Health Scaling (defense).
Keystones
| Rune | Players | Win Rate | Games |
|---|---|---|---|
| First StrikeMost played | 55.9% | 52.0% | 2,444 |
 Electrocute | 37.2% | 47.1% | 1,625 |
 Conqueror | 5.6% | 49.0% | 243 |
Secondary trees
| Rune | Players | Win Rate | Games |
|---|---|---|---|
 PrecisionMost played | 66.5% | 51.3% | 2,905 |
 Sorcery | 27.0% | 46.8% | 1,179 |
 Resolve | 3.2% | 48.2% | 139 |
 Domination | 2.3% | 44.4% | 99 |
| Inspiration | 1.1% | 60.4% | 48 |
Pick rate is the share of Zed games in this lane that used the rune; options under 40 games are left out. A higher win rate on a rarely picked rune is usually a matchup-specific choice, not a general upgrade.
Zed Minor Runes by Tree
Every minor rune Zed players take, grouped by rune tree, with how often it is picked and how often it wins.
Precision
| Rune | Players | Win Rate | Games |
|---|---|---|---|
| Legend: HasteMost played | 56.9% | 52.4% | 2,487 |
| Cut Down | 52.7% | 52.9% | 2,302 |
 Coup de Grace | 15.9% | 46.9% | 693 |
 Triumph | 14.1% | 47.6% | 616 |
 Presence of Mind | 7.4% | 47.7% | 323 |
 Last Stand | 2.2% | 38.5% | 96 |
Inspiration
| Rune | Players | Win Rate | Games |
|---|---|---|---|
| Cash BackMost played | 55.5% | 52.3% | 2,428 |
| Triple Tonic | 55.4% | 52.2% | 2,423 |
| Jack Of All Trades | 33.2% | 53.1% | 1,453 |
 Cosmic Insight | 23.0% | 50.7% | 1,004 |
 Magical Footwear | 1.3% | 46.6% | 58 |
Domination
| Rune | Players | Win Rate | Games |
|---|---|---|---|
 Ultimate HunterMost played | 38.1% | 46.8% | 1,666 |
 Grisly Mementos | 35.2% | 46.7% | 1,539 |
 Taste of Blood | 19.8% | 46.4% | 867 |
 Sudden Impact | 19.6% | 47.2% | 856 |
 Sixth Sense | 2.0% | 56.2% | 89 |
 Treasure Hunter | 1.5% | 48.5% | 66 |
Sorcery
| Rune | Players | Win Rate | Games |
|---|---|---|---|
 TranscendenceMost played | 24.8% | 47.1% | 1,082 |
 Scorch | 22.0% | 46.5% | 960 |
 Axiom Arcanist | 3.8% | 47.9% | 167 |
 Gathering Storm | 1.9% | 51.8% | 85 |
 Nimbus Cloak | 1.4% | 45.2% | 62 |
Resolve
| Rune | Players | Win Rate | Games |
|---|---|---|---|
 Bone PlatingMost played | 2.1% | 47.3% | 93 |
 Overgrowth | 1.5% | 44.6% | 65 |
 Second Wind | 1.0% | 50.0% | 44 |
 Unflinching | 1.0% | 45.2% | 42 |
Zed Stat Shards
Which stat shards Zed players choose in each of the three shard rows, and the win rate of each.
| Rune | Players | Win Rate | Games |
|---|---|---|---|
 Adaptive Force (flex)Most played | 98.6% | 49.9% | 4,308 |
| Adaptive Force (offense) | 93.3% | 49.9% | 4,078 |
 Health Scaling (defense) | 84.4% | 49.3% | 3,687 |
| Health (defense) | 11.6% | 55.8% | 509 |
 Tenacity and Slow Resist (defense) | 4.0% | 47.4% | 175 |
 Attack Speed (offense) | 3.5% | 45.0% | 151 |
 Ability Haste (offense) | 3.2% | 57.0% | 142 |
 Move Speed (flex) | 1.1% | 56.5% | 46 |
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Zed Runes FAQ - Patch 26.20
What is the best keystone for Zed Mid?
First Strike: Zed Mid takes it in 56% of ranked games and wins 52.0% of 2,444 games. Alternatives: Electrocute (37%, 47.1%), Conqueror (6%, 49.0%).
What stat shards should Zed take?
Most Zed players take Adaptive Force (offense), Adaptive Force (flex), Health Scaling (defense) — one from each shard row.
What are the best Zed runes in patch 26.20?
The best Zed runes in patch 26.20 use the Inspiration tree with First Strike, Cash Back, Triple Tonic, and Jack Of All Trades, and the Precision tree with Legend: Haste and Cut Down. This rune setup achieves a 63.8% win rate with a 2.3% pick rate.
What is the win rate for Zed's best rune page?
Zed's best rune page has a 63.8% win rate in patch 26.20, which is +13.6% compared to Zed's average win rate. This rune setup has a 2.3% pick rate among Zed players.
What keystone should I use on Zed?
First Strike from the Inspiration tree is the best keystone rune for Zed in patch 26.20. This keystone synergizes well with Zed's kit and provides a 63.8% win rate.
What is Zed's primary rune tree?
Zed's primary rune tree is Inspiration. The optimal Inspiration runes for Zed are First Strike, Cash Back, Triple Tonic, and Jack Of All Trades, with First Strike being the keystone of choice.
What is Zed's secondary rune tree?
Zed's best secondary rune tree is Precision. The recommended Precision runes are Legend: Haste and Cut Down, which complement Zed's Inspiration primary tree.
What are alternative rune setups for Zed?
An alternative Zed rune setup uses First Strike from the Inspiration tree. This alternate build may be preferred in certain matchups or playstyles. Check the alternative rune page above for full details including win rate and pick rate.
How popular are Zed's runes?
Zed's top rune page has a 2.3% pick rate in patch 26.20. This indicates that 2.3% of Zed players use the First Strike setup with Inspiration and Precision trees.