Alignment•Skill

Is Alignment good in Slay the Spire 2?

In Slay the Spire 2, Alignment is an uncommon skill from the Regent card pool. Its effect: Gain Energy. Performance-wise it’s a solid if unspectacular include, rated C tier overall.

Over 92 tracked runs its win rate sits at 32.0%, 13.1% ahead of the 18.9% all-deck baseline. It sees niche play, included in only 2.4% of eligible runs. Within Regent runs it’s drafted 13.3% of the time, making it a regular part of that class’s decks. Decks that include it run about 1.1 copies on average.

Its standout pairing so far is Cosmic Indifference, which lifts its win rate by +22.6% when the two share a deck. On the relic side, Anchor is its standout companion, worth a +25.4% win-rate swing alongside it. It costs 0 energy, gets upgraded 25.0% of the time, and tends to be picked up near floor 16.

Upgrading the card adds +1 Energy to its stat line. Of the runs that drafted it, 25 ended in victory against 53 deaths and 14 abandons. Its most common run-ender is Phrog Parasite Elite, finishing 4.3% of the runs it shows up in. See the synergies, class split, and threats below for the full picture of where Alignment fits a Regent deck.

Best Cards to Pair with Alignment

Alignment’s strongest card pairings so far are Cosmic Indifference (+22.6%), Sword Sage (+22.1%), and Comet (+19.0%), each shown with the win-rate lift it adds.

Cosmic Indifference+22.6%17 runsSword Sage+22.1%7 runsComet+19.0%10 runsStardust+18.7%20 runsMad Science+16.2%7 runsQuasar+14.9%17 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Alignment Win Rate by Class

Of the 2 classes that draft Alignment, it performs best with Regent (32.0%) and Ironclad (0.0%).

The Regent32.0%91 runsThe Ironclad0.0%1 runs

Best Relics for Alignment

The relics that swing Alignment’s win rate the most are Anchor (+25.4%), Mr. Struggles (+19.4%), and Fencing Manual (+19.2%), with each lift shown.

Anchor+25.4%13 runsMr. Struggles+19.4%4 runsFencing Manual+19.2%7 runsBeating Remnant+19.2%6 runsLantern+19.0%11 runsBronze Scales+18.8%16 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Alignment Card Details

A 0-energy uncommon skill, Alignment is upgraded 25.0% of the time and tends to enter the deck around floor 16.

Gain Energy.

Upgrade: +1 Energy

What Ends Runs with Alignment

Runs holding Alignment end most often against Phrog Parasite Elite (4.3%), Infested Prisms Elite (3.3%), and Vantom Boss (3.3%) — the share of its runs each accounts for is shown.

• Phrog Parasite Elite4.3% of runs
• Infested Prisms Elite3.3% of runs
• Vantom Boss3.3% of runs
• The Insatiable Boss3.3% of runs
• Kaiser Crab Boss3.3% of runs

See Also

Keep exploring Slay the Spire 2 tier lists and stats below.