Bloodletting•Skill

Is Bloodletting good in Slay the Spire 2?

In Slay the Spire 2, Bloodletting is a common skill from the Ironclad card pool. Its effect: Lose 3 HP. Gain Energy. The data flags it as a weaker pick, settling at D tier — usually one to pass on unless your deck specifically wants it.

Over 954 tracked runs its win rate sits at 22.7%, 8.8% ahead of the 14.0% all-deck baseline. It sees niche play, included in only 8.3% of eligible runs. When it is actually offered players take it 32.1% of the time, and that looks correct: those runs win 22.9% against 15.3% for runs that passed, a +7.5% pick lift over 802 decided runs. Within Ironclad runs it’s drafted 34.7% of the time, making it a regular part of that class’s decks. Decks that include it run about 1.3 copies on average.

Its standout pairing so far is Prolong, which lifts its win rate by +33.8% when the two share a deck. On the relic side, Royal Stamp is its standout companion, worth a +33.6% win-rate swing alongside it. It costs 0 energy, gets upgraded 29.9% of the time, and tends to be picked up near floor 14.

Upgrading the card adds +1 Energy to its stat line. Of the runs that drafted it, 215 ended in victory against 731 deaths and 8 abandons. Its most common run-ender is Test Subject Boss, finishing 6.2% of the runs it shows up in. See the synergies, class split, and threats below for the full picture of where Bloodletting fits a Ironclad deck.

Pick or Skip: Bloodletting

Players take Bloodletting in 32.1% of the 2956 offers it appears in; those runs win 22.9% against 15.3% for runs that passed, a pick lift of +7.5% over 802 decided runs.

Taken 950 times out of 2956 offers.

Pick rate when offered counts offers, not runs: out of every time the game put this in front of a player, how often it was taken. It is not the same number as the share of runs that end up containing it.

Pick lift is the sample-adjusted gap between runs that took the option and runs that passed on it. It is the fair way to rank choices, because raw win rates put the smallest samples on top.

When to Pick Up Bloodletting

Of the 4 pickup windows recorded for Bloodletting, Act 3 is the best: 54.4% across 79 runs.

Win rate of runs by the act Bloodletting entered the deck. Acts that have not reached the sample floor show their run count only.

Best Cards to Pair with Bloodletting

Bloodletting’s strongest card pairings so far are Prolong (+33.8%), Mad Science (+29.1%), and Cascade (+22.2%), each shown with the win-rate lift it adds.

Prolong+33.8%17 runsMad Science+29.1%58 runsCascade+22.2%65 runsDemonic Shield+21.8%40 runsRegret+19.0%17 runsAggression+18.1%70 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Bloodletting Win Rate by Class

Exclusive to the Ironclad, Bloodletting posts a 22.9% win rate over 937 tracked runs.

The Ironcladappears in 34.7% of its runs (937 tracked)

Best Relics for Bloodletting

The relics that swing Bloodletting’s win rate the most are Royal Stamp (+33.6%), Molten Egg (+29.3%), and Chemical X (+28.3%), with each lift shown.

Royal Stamp+33.6%26 runsMolten Egg+29.3%29 runsChemical X+28.3%17 runsRuined Helmet+28.3%16 runsCloak Clasp+26.7%33 runsUnsettling Lamp+26.7%27 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Bloodletting Card Details

A 0-energy common skill, Bloodletting is upgraded 29.9% of the time and tends to enter the deck around floor 14.

Lose 3 HP. Gain Energy.

Upgrade: +1 Energy

What Ends Runs with Bloodletting

Runs holding Bloodletting end most often against Test Subject Boss (6.2%), Kaiser Crab Boss (6.0%), and Queen Boss (5.1%) — the share of its runs each accounts for is shown.

• Test Subject Boss6.2% of runs
• Kaiser Crab Boss6.0% of runs
• Queen Boss5.1% of runs
• Knowledge Demon Boss4.6% of runs
• The Insatiable Boss4.3% of runs

See Also

Keep exploring Slay the Spire 2 tier lists and stats below.