Chemical XRelic
The effects of your cost X cards are increased by.
Is Chemical X good in Slay the Spire 2?
In Slay the Spire 2, Chemical X is a shop relic you can pick up on your climb. Its effect: The effects of your cost X cards are increased by. Right now it’s a high-value grab, sitting at B tier — one of the relics most worth taking.
Over 24 tracked runs the win rate of decks holding it sits at 59.1%, 40.1% ahead of the 19.0% all-run baseline. It sees lighter play, carried in only 0.6% of runs. It does its best work in the hands of the Necrobinder, who post a 80.0% win rate with it. Within Necrobinder runs specifically, it’s carried 0.7% of the time.
Its standout card pairing is Debilitate, which lifts the relic’s win rate by +40.9% when both are in play. It also works nicely with Defy, good for a +40.9% win-rate change. It typically enters the deck near floor 30. As a shop relic, how often it’s offered depends on its rarity tier.
Of the runs that carried it, 13 ended in victory while 9 fell to a defeat. Its most common run-ender is Test Subject Boss, finishing 16.7% of the runs it appears in. See the best cards, class split, and threats below for the full read on whether Chemical X is worth grabbing.
Chemical X Win Rate & Pick Rate
At a 59.1% win rate, Chemical X runs 40.1% ahead of the 19.0% all-run baseline — the bars below put the two side by side.
Run Outcomes with Chemical X
Across the 24 runs that carried Chemical X, 13 ended in a win and 11 in a loss — a 54.2% win share, counting abandons as losses.
- Wins 54.2%
- Losses 45.8%
Best Cards with Chemical X
The cards that gain the most from carrying Chemical X are Debilitate (+40.9%), Defy (+40.9%), and Haunt (+40.9%), each shown with its win-rate swing.
Based on small co-occurring samples — treat these as early signals, not final verdicts.
Chemical X Win Rate by Class
Of the 4 classes that carry Chemical X, it performs best with Necrobinder (80.0%), Ironclad (55.6%), and Regent (50.0%).
Chemical X Details
Carried in 0.6% of runs, Chemical X is a shop relic typically acquired near floor 30.
The effects of your cost X cards are increased by.
What Ends Runs with Chemical X
Runs carrying Chemical X end most often against Test Subject Boss (16.7%) — the share of its runs each accounts for is shown.
- Test Subject Boss16.7% of runs
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Chemical X – Frequently Asked Questions
Is Chemical X good in Slay the Spire 2?
Across 24 tracked runs carrying it, Chemical X wins 59.1% of the time — +40.1% above the average run. Win rate reflects how often runs with the relic end in victory.
What does Chemical X do in Slay the Spire 2?
The effects of your cost X cards are increased by.
How rare is Chemical X in Slay the Spire 2?
Chemical X is a Shop relic, picked up in 0.6% of tracked runs.
What is the best card to use with Chemical X?
In tracked runs, Chemical X has performed best alongside Debilitate, which lifts its win rate by +40.9% over 3 runs together.
Which class is Chemical X best in?
Chemical X has its highest win rate with The Necrobinder (80.0%).
See Also
Keep exploring Slay the Spire 2 tier lists and stats below.