Boot Sequence•Skill

Is Boot Sequence good in Slay the Spire 2?

Boot Sequence is an uncommon Defect skill in Slay the Spire 2. In combat it resolves as: Gain 10 Block. It currently underperforms most alternatives, sitting at F tier in our Slay the Spire 2 card rankings.

Across 114 recorded runs, decks running it win 15.7% of the time, trailing the 18.9% average by 3.3%. It’s a more selective pick, turning up in just 3.0% of decks that could run it. Silent players keep it in 0.2% of their runs, so it’s a familiar sight in those decks. On average it shows up 1.1 times in the decks that take it.

It performs best next to All for One — together they post a +18.6% swing in win rate. It also has strong chemistry with the relic Joss Paper, which moves its win rate by +21.4%. At 0 energy, it’s upgraded in 23.8% of runs and usually joins the deck around floor 15.

Upgraded, it gains +3 Block, which is why so many decks invest a rest-site upgrade in it. That’s 16 wins, 86 deaths, and 12 abandoned runs with it in the deck. The encounter that most often ends a run carrying it is Queen Boss, which closes out 10.5% of its appearances. Read on for Boot Sequence’s complete synergy, class, and threat breakdown to decide whether it earns a slot in your Defect run.

Best Cards to Pair with Boot Sequence

Ranked by win-rate lift, Boot Sequence performs best alongside All for One (+18.6%), FTL (+14.9%), and Production (+14.8%).

All for One+18.6%16 runsFTL+14.9%20 runsProduction+14.8%5 runsRocket Punch+13.6%10 runsSpinner+12.3%19 runsProlong+11.8%3 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Boot Sequence Win Rate by Class

Boot Sequence is played across 3 classes, led by Silent (50.0%), Defect (15.2%), and Necrobinder (0.0%) by win rate.

The Silent50.0%2 runsThe Defect15.2%111 runsThe Necrobinder0.0%1 runs

Best Relics for Boot Sequence

Boot Sequence pairs best with the relics Joss Paper (+21.4%), Permafrost (+15.6%), and Juzu Bracelet (+15.3%), ranked by win-rate lift.

Joss Paper+21.4%5 runsPermafrost+15.6%11 runsJuzu Bracelet+15.3%9 runsStrawberry+14.9%20 runsIntimidating Helmet+14.8%5 runsBronze Scales+14.6%17 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Boot Sequence Card Details

Boot Sequence is an uncommon skill costing 0 energy; it’s upgraded in 23.8% of runs and usually picked up by floor 15.

Gain 10 Block.

Upgrade: +3 Block

What Ends Runs with Boot Sequence

Boot Sequence’s most common run-enders are Queen Boss (10.5%), Knowledge Demon Boss (5.3%), and Kaiser Crab Boss (4.4%).

• Queen Boss10.5% of runs
• Knowledge Demon Boss5.3% of runs
• Kaiser Crab Boss4.4% of runs
• Doormaker Boss3.5% of runs
• Infested Prisms Elite3.5% of runs

See Also

Compare Boot Sequence with the rest of the best Slay the Spire 2 cards, relics, and classes below.