Squeeze Attack

Is Squeeze good in Slay the Spire 2?

Squeeze is a rare Necrobinder attack in Slay the Spire 2. In combat it resolves as: Osty deals 25 damage. Deals 5 additional damage for ALL your other Osty Attacks. It’s a dependable, middle-of-the-pack option, landing at C tier in our rankings.

Across 227 recorded runs, decks running it win 31.0% of the time, comfortably clear of the 13.8% average, by 17.1%. It’s a more selective pick, turning up in just 1.1% of decks that could run it. Offer data is close to a wash — 26.6% of offers taken, 33.3% for runs that picked it against 33.3% for runs that skipped, a pick lift of just +0.1% over 171 decided runs. Necrobinder players keep it in 6.3% of their runs, so it’s a familiar sight in those decks. On average it shows up 1.2 times in the decks that take it.

It performs best next to Eradicate — together they post a +24.9% swing in win rate. It also has strong chemistry with the relic Lantern, which moves its win rate by +29.2%. At 3 energy, it’s upgraded in 47.5% of runs and usually joins the deck around floor 16.

Upgraded, it gains +5 CalculationBase, +1 ExtraDamage, which is why so many decks invest a rest-site upgrade in it. That’s 70 wins, 156 deaths, and 1 abandoned runs with it in the deck. The encounter that most often ends a run carrying it is Knowledge Demon Boss, which closes out 7.0% of its appearances. Read on for Squeeze’s complete synergy, class, and threat breakdown to decide whether it earns a slot in your Necrobinder run.

Pick or Skip: Squeeze

Out of 704 recorded offers Squeeze is taken 26.6% of the time, and taking it is worth +0.1% in pick lift — 33.3% for runs that picked it against 33.3% for runs that skipped, across 171 decided runs.

Taken 187 times out of 704 offers.

Pick rate when offered counts offers, not runs: out of every time the game put this in front of a player, how often it was taken. It is not the same number as the share of runs that end up containing it.

Pick lift is the sample-adjusted gap between runs that took the option and runs that passed on it. It is the fair way to rank choices, because raw win rates put the smallest samples on top.

When to Pick Up Squeeze

Squeeze is strongest when it joins the deck in Act 3, where runs win 72.7% across 11 runs — one of 3 recorded pickup windows.

Win rate of runs by the act Squeeze entered the deck. Acts that have not reached the sample floor show their run count only.

Best Cards to Pair with Squeeze

Ranked by win-rate lift, Squeeze performs best alongside Eradicate (+24.9%), Demesne (+21.5%), and Misery (+20.8%).

Eradicate+24.9%17 runsDemesne+21.5%34 runsMisery+20.8%23 runsNeurosurge+20.4%35 runsLegion of Bone+17.4%15 runsShared Fate+16.0%20 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Squeeze Win Rate by Class

Squeeze is drafted only by the Necrobinder, where it holds a 31.0% win rate across 227 runs.

The Necrobinderappears in 6.3% of its runs (227 tracked)

Best Relics for Squeeze

Squeeze pairs best with the relics Lantern (+29.2%), Ornamental Fan (+26.9%), and Akabeko (+26.0%), ranked by win-rate lift.

Lantern+29.2%40 runsOrnamental Fan+26.9%23 runsAkabeko+26.0%20 runsParrying Shield+25.4%15 runsBone Flute+25.4%31 runsVenerable Tea Set+23.8%34 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Squeeze Card Details

Squeeze is a rare attack costing 3 energy; it’s upgraded in 47.5% of runs and usually picked up by floor 16.

Osty deals 25 damage. Deals 5 additional damage for ALL your other Osty Attacks.

Upgrade: +5 CalculationBase, +1 ExtraDamage

What Ends Runs with Squeeze

Squeeze’s most common run-enders are Knowledge Demon Boss (7.0%), Test Subject Boss (6.2%), and Decimillipede Elite (5.7%).

• Knowledge Demon Boss7.0% of runs
• Test Subject Boss6.2% of runs
• Decimillipede Elite5.7% of runs
• Queen Boss4.4% of runs
• Infested Prisms Elite4.0% of runs

See Also

Compare Squeeze with the rest of the best Slay the Spire 2 cards, relics, and classes below.