Infused Core•Relic

Is Infused Core good in Slay the Spire 2?

Infused Core is a starter relic in Slay the Spire 2. While carried, it does the following: At the start of each combat, Channel Lightning. It currently underperforms most relics, sitting at D tier in our Slay the Spire 2 relic rankings.

Across 34 recorded runs, decks carrying it win 37.5% of the time, comfortably clear of the 18.9% average, by 18.6%. It’s a more situational relic, showing up in just 0.9% of runs. The class that gets the most out of it is the Defect, at a 37.5% win rate. Defect players hold onto it in 5.8% of their runs.

It combos especially well with Scrape, worth a +62.5% win-rate swing together. Another strong card to run with it is Rocket Punch, worth +62.5% to its win rate. On average it’s acquired around floor 18 of a run. Its starter rarity shapes how frequently you’ll run into it.

It has 12 run wins against 20 losses in our tracked data. When runs carrying it end, the most frequent culprit is Kaiser Crab Boss, which closes out 11.8% of them. Read on for Infused Core’s complete card, class, and threat breakdown before you decide to pick it up.

Best Cards with Infused Core

Ranked by win-rate lift, the best cards to run with Infused Core are Scrape (+62.5%), Rocket Punch (+62.5%), and Iteration (+42.5%).

Scrape+62.5%4 runsRocket Punch+62.5%5 runsIteration+42.5%6 runsFight Through+42.5%5 runsMachine Learning+42.5%5 runsNull+37.5%4 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Infused Core Win Rate by Class

So far Infused Core is carried mainly by the Defect, who win 37.5% of their runs with it across 34 tracked.

The Defectappears in 5.8% of its runs (34 tracked)

Infused Core Details

Infused Core is a starter relic carried in 0.9% of runs and usually picked up around floor 18.

At the start of each combat, Channel Lightning.

What Ends Runs with Infused Core

Infused Core’s most common run-enders are Kaiser Crab Boss (11.8%), Aeonglass Boss (8.8%), and Queen Boss (8.8%).

• Kaiser Crab Boss11.8% of runs
• Aeonglass Boss8.8% of runs
• Queen Boss8.8% of runs
• Test Subject Boss5.9% of runs

See Also

Compare Infused Core with the rest of the best Slay the Spire 2 relics, cards, and classes below.