Annie - League of Legends Champion
Win Rate
50.0%
Pick Rate
1.4%

Annievs Lissandra

CMageSupport
Patch26.7
Matches949,984
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 21, 2026
MethodologyData Methodology

Annie vs Lissandra is a decisive matchup in LoL patch 26.7. Lissandra wins with a 66.7% win rate (+33.3%) over Annie based on 24 games. Lissandra holds the advantage in both the early and late game. Below you'll find the best Annie build, runes, laning stats, and strategies for the Annie vs Lissandra matchup.

Annie Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Annie performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Lissandra - 33.3% win rateLissandra(33.3%)
Annie - 33.3% win rate in this matchup
Annie
33.3% WR
VS
Lissandra vs Annie matchup - 66.7% win rate
Lissandra
66.7% WR

Who Wins the Annie vs Lissandra Matchup?

Lissandra wins the Annie vs Lissandra matchup
Winner
Lissandra
Matches: 24
33.3%
Win Rate
66.7%
6.3
CS / min
7.1
875
DMG / min
788
10,525
Gold / game
11,244
70
Heal / min
161
461
DMG Mitigated / min
404
0.9
CC / min
1.5
45.5%
Early Game WR
54.5%
23.1%
Late Game WR
76.9%

Annie vs Lissandra Matchup Summary

The Annie vs Lissandra matchup is a decisive matchup in League of Legends ranked play. Based on 24 recent matches analyzed, Lissandra wins with a 66.7% win rate compared to Annie's 33.3%, giving Lissandra a 33.3 percentage point advantage. Lissandra dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Annie players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Lissandra leads by 0.5s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Lissandra has a strong advantage in this matchup. Annie players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Lissandra overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Annie vs Lissandra Laning Phase Breakdown

Lissandra wins the laning phase against Annie in League of Legends

Lissandra is favored during the laning phase against Annie, winning 4 out of 5 key stat categories. Lissandra holds advantages in farming, gold income, crowd control and sustain, making them the stronger laner in this matchup.

Farming
6.3Annie
7.1Lissandra
Lissandra significantly out-farms Annie by 0.9 CS per minute, accumulating an estimated 13 CS lead by mid game. This substantial farming gap gives Lissandra a major gold advantage and earlier item completions. Annie players should prioritize wave management techniques like freezing near tower and using abilities efficiently to minimize the deficit.
Damage
875Annie
788Lissandra
Annie heavily out-damages Lissandra by 87 DMG/min, dominating both short trades and all-in fights. Lissandra should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Annie's sustained damage advantage take over.
Economy
10,525Annie
11,244Lissandra
Lissandra earns 719 more gold per game than Annie, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Lissandra slightly faster item completions.
Utility
0.9Annie
1.5Lissandra
Lissandra provides 0.5 seconds more crowd control per minute than Annie, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Lissandra coordinate with their jungler and control the pace of skirmishes.
Sustain
531Annie
564Lissandra
Annie and Lissandra have comparable sustain profiles, with only 34 HP/min separating their healing and damage mitigation. Neither champion can out-attrition the other in lane, so trades will be decided by burst potential and ability usage rather than sustain.

Best Annie Build Against Lissandra

Spellslinger's Shoes is the optimal boots choice against Lissandra, providing the mobility and stats Annie needs most in this matchup. The top-performing core items for Annie against Lissandra are Stormsurge, Shadowflame and Malignance. This combination gives Annie an effective balance of damage, survivability, and utility for the matchup. This build has a 40.0% win rate across 5 games. While the overall matchup may be difficult, this item path gives Annie the best chance to compete against Lissandra. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Annie vs Lissandra matchup.

Early Game vs Late Game

Early Game
Lissandra
54.5%
+9.1% advantage
Annie early game win rateAnnie45.5%
Lissandra early game win rateLissandra54.5%
Late Game
Lissandra
76.9%
+53.8% advantage
Annie late game win rateAnnie23.1%
Lissandra late game win rateLissandra76.9%

Lissandra dominates the early game (first 15 minutes) with a commanding 54.5% win rate — a 9.1 percentage point lead over Annie. This lopsided early game means Lissandra can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Lissandra is far superior in the late game (25+ minutes), boasting a 76.9% win rate — 53.8 points above Annie. Extended games heavily favor Lissandra, whose kit and scaling make them a dominant force in team fights and objective control.

Lissandra holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Annie players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Annie Runes Against Lissandra

Domination rune tree - Annie primary runes vs LissandraDomination
Electrocute - best Annie rune vs LissandraCheap Shot - best Annie rune vs LissandraSixth Sense - best Annie rune vs LissandraRelentless Hunter - best Annie rune vs Lissandra
Sorcery rune tree - Annie secondary runes vs LissandraSorcery
Absolute Focus - best Annie rune vs LissandraAxiom Arcanist - best Annie rune vs Lissandra
100.0% WR

The Domination and Sorcery rune setup gives Annie the best tools to compete against Lissandra in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Annie matchup data for League of Legends patch 26.7. The table below shows Annie's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Annie build, runes, laning stats, and early vs late game analysis for that specific matchup.

Annie matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
45.98%876.094612,03938.5%52.1%
42.86%845.986911,27542.5%43.2%
46.00%505.580410,85652.2%40.7%
60.00%505.596211,12952.2%66.7%
55.00%406.093311,39656.5%52.9%
43.59%395.791511,94221.4%56.0%
45.95%375.886912,18741.7%48.0%
55.56%365.384211,00158.8%52.6%
54.29%355.087211,89464.3%47.6%
47.06%345.889510,88735.0%64.3%
37.50%325.796611,72316.7%50.0%
43.33%305.978810,94758.3%33.3%
46.67%305.484012,03137.5%50.0%
44.83%295.871310,38826.7%64.3%
71.43%285.999912,33466.7%76.9%
46.43%285.286310,62838.5%53.3%
48.15%274.282911,46650.0%47.4%
46.15%266.093111,78455.6%41.2%
52.00%256.076910,39233.3%69.2%
33.33%246.387510,52545.5%23.1%
43.48%235.894212,20030.0%53.9%
50.00%225.596811,66666.7%38.5%
30.00%205.582410,34033.3%25.0%
45.00%206.390710,00846.1%42.9%
47.37%195.483011,54312.5%72.7%
33.33%185.21,02611,54730.0%37.5%
70.59%175.875611,05275.0%66.7%
37.50%163.68529,59312.5%62.5%
43.75%166.488710,48150.0%33.3%
37.50%165.782811,50060.0%27.3%
53.33%151.46229,27950.0%55.6%
66.67%156.397811,67170.0%60.0%
61.54%135.372811,40175.0%55.6%
33.33%121.75498,22333.3%33.3%
50.00%121.66919,77057.1%40.0%
41.67%125.194712,03860.0%28.6%
54.55%112.15998,84542.9%75.0%
90.91%114.08319,13785.7%100.0%
45.45%115.51,06912,73325.0%57.1%
70.00%106.588311,780100.0%25.0%
40.00%102.27229,90140.0%40.0%
60.00%105.61,09311,46860.0%60.0%
50.00%106.11,01511,96260.0%40.0%
44.44%96.889112,01120.0%75.0%
33.33%95.29477,19850.0%0.0%
66.67%94.775710,24450.0%80.0%
75.00%81.87039,69180.0%66.7%
62.50%82.977911,22366.7%60.0%
37.50%82.66579,5510.0%50.0%
62.50%81.771711,07660.0%66.7%
85.71%75.694313,370100.0%80.0%
0.00%74.85678,1960.0%0.0%
57.14%75.684711,61166.7%50.0%
71.43%73.56829,60533.3%100.0%
42.86%76.38668,90325.0%66.7%
42.86%75.994313,302100.0%33.3%
85.71%75.195912,52950.0%100.0%
50.00%65.697412,5110.0%60.0%
50.00%64.57117,57525.0%100.0%
66.67%61.251210,7010.0%80.0%
33.33%65.492913,7750.0%40.0%
50.00%65.41,19514,59350.0%50.0%
60.00%54.690112,9020.0%75.0%
60.00%55.01,01012,9840.0%60.0%
20.00%52.35038,22725.0%0.0%

Get the MetaBot Desktop App

Level up your gameplay with real-time overlays, automatic game detection, and instant stats — all on your desktop.

In-game overlaysAuto game detectionMulti-game supportPersonal dashboard
Download NowFree download
🔍

Help us maintain accuracy! If you notice incorrect stats, missing data, or any issues, your feedback directly improves the quality of our data for the entire community.

Report an Issue

Annie vs Lissandra - Frequently Asked Questions

How does Annie do against Lissandra in League of Legends?

Lissandra wins the Annie vs Lissandra matchup with a 66.7% win rate compared to Annie's 33.3%, a 33.3 percentage point difference. This data is based on 24 recent ranked games in patch 26.7.

How does Annie do against Lissandra in the early game?

In the early game, Lissandra has the advantage against Annie with a 54.5% win rate versus 45.5%. Lissandra players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Annie do against Lissandra in the late game?

In the late game, Lissandra takes over the Annie vs Lissandra matchup with a 76.9% win rate compared to 23.1%. Lissandra scales better into team fights and objective contests after 25 minutes.

Who wins the Annie vs Lissandra matchup?

Lissandra wins the matchup against Annie with a 66.7% win rate in League of Legends patch 26.7. The 33.3 percentage point advantage means Lissandra is significantly favored in this lane matchup based on 24 games analyzed.

What is the best Annie build against Lissandra?

The best Annie build against Lissandra includes Stormsurge, Shadowflame, Malignance with Spellslinger's Shoes. This build achieves a 40.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Annie runes against Lissandra?

The best Annie runes against Lissandra use the Domination primary tree with Sorcery secondary. This rune setup achieves a 100.0% win rate in the Annie vs Lissandra matchup. See the full rune breakdown in the matchup comparison above.

Does Annie counter Lissandra?

No, Annie struggles against Lissandra with only a 33.3% win rate. Lissandra has the advantage in this matchup. Annie players should focus on safe farming and avoiding extended trades to minimize Lissandra's lead.

How do I play Annie against Lissandra?

When playing Annie against Lissandra, play cautiously and avoid Lissandra's power spikes. Look for jungle assistance and team-dependent plays since Lissandra has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.