- Win Rate
- 52.0%
- Pick Rate
- 1.2%
- Ban Rate
- 0.9%
Annie vs Lissandra
- Patch
- 26.19
- Games
- 1,061
- Lane
- All Lanes
- Tier
- All Tiers
- Last Updated
- Oct 5, 2026 UTC
- Methodology
- Data Methodology
- Author
- Dakota Chinnick
Annie vs Lissandra is a very close matchup in LoL patch 26.19. Annie wins with a 50.0% win rate (+0.0%) over Lissandra based on 12 games. Lissandra wins the early laning phase while Annie scales better into the late game. Below you'll find the best Annie build, runes, laning stats, and strategies for the Annie vs Lissandra matchup.
Annie Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Annie performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who wins Annie vs Lissandra?
Annie wins 39.3% of these games. With this many games the true rate is most likely between 23.6% and 57.6% (95% range).
- Expected
- 51.1% From both champions' overall Mid win rates
- Matchup effect
- −11.9 pts Observed minus expected
- Sample
- 28 games Lane: Mid
- vs patch 26.18
- — Not enough games on both patches
Lane: Mid · Ranked Solo/Duo & Flex · North America server · All ranks · Patch 26.19 · Sep 24 – Sep 28
Key takeaways
- Current data slightly favors Lissandra, but the sample is too limited for a strong conclusion: Annie wins 39.3% of 28 games (95% range 23.6–57.6%).
- Both champions' overall Mid win rates predict 51.1% for Annie; the result is within the margin of error of that, so this matchup mostly reflects the two champions' general strength.
- Annie players pick Rabadon's Deathcap far more often against Lissandra: 15.0% of their other Mid games, 32.1% here.
How we calculate this
Games: ranked Solo/Duo and Flex games on the North America server from the patch shown. Remakes (games under 5 minutes) are excluded.
A game only counts when Annie and Lissandra played the same position on opposite teams, so roaming, lane swaps within a team or a champion merely being in the same game never count as this matchup.
The 95% range is a Wilson score interval. Confidence comes from how wide that range is: within ±3 points is very high, ±5 high, ±8 moderate, anything wider low. Below 20 games a matchup is not classified at all.
Expected win rate combines both champions’ win rates in this lane (same games and filters) with the log5 formula: E = A(1−B) / (A(1−B) + B(1−A)). Matchup effect = observed − expected.
"What changes" compares Annie's choices in this matchup with the same champion's other games in the same lane, and lists a change only when it is at least 3 points and statistically significant (two-proportion z-test, |z| ≥ 2, 20+ games).
Results are not split by rank: the sample per rank is too small for honest per-rank matchup numbers.
Annie vs Lissandra Laning Stats
Only 27 games have a 15-minute snapshot so far — the lane-phase numbers appear from 30.
Whole-game averages
Annie vs Lissandra Win Rate by Game Length
Annie's win rate against Lissandra by game length. The dot is the win rate, the bar its 95% range and the dashed line the champion's usual win rate at that length. Lengths with fewer than 25 games are left blank.
No game length stands out: Annie's results against Lissandra in short and long games are within the margin of error of each other.
Annie vs Lissandra Power Spikes
Who is ahead at each stage, measured from these games. A stage reads "Even" when the difference is inside the margin of error, and "Insufficient data" when there are too few games to tell.
- Lane (15 min)Insufficient data
- First itemInsufficient data
- Games under 20 minInsufficient data
- 20–30 min gamesInsufficient data
- 30+ min gamesInsufficient data
What Annie Changes Against Lissandra
Choices Annie players make noticeably more or less often in this matchup than in their other Mid games.
Usually15.0%vs Lissandra32.1%+17.1 pts
First StrikeKeystoneUsually1.6%vs Lissandra10.7%+9.1 pts
Health Potion + Health Potion + Tear of the Goddess + Stealth WardStarting itemsUsuallyunder 0.5%vs Lissandra3.6%+3.6 pts
Doran's Ring + Health PotionStarting itemsUsuallyunder 0.5%vs Lissandra3.6%+3.6 pts
Sapphire Crystal + Refillable PotionStarting itemsUsuallyunder 0.5%vs Lissandra3.6%+3.6 pts
Best Annie Build vs Lissandra
Against Lissandra
Not enough matchup-specific build data: only 2 of 15 Annie games against Lissandra carried a complete build, which is too few to recommend an item path from. Use Annie's standard build instead.
- Annie usually completes Malignance first, at 11.0 min (median of 21 games).
- Skill priority: Q > W > E — the same as usual.
Builds are ranked by the lower edge of their win rate range, not the raw win rate, so a build seen in a handful of wins never outranks a proven one.
Best Annie Runes vs Lissandra
Usual Annie runes (Mid)
Electrocute
69.0% win rate · 29 games
Against Lissandra
Too few games for a matchup-specific rune page yet — use the usual page.
Plan your Annie draft in Draft Lab
Draft Lab lays out both teams lane by lane with live matchup win rates, damage profiles and game-phase lean, and suggests picks and bans from current meta data.
- Full 5v5 draft board
- Lane matchup win rates
- Pick and ban suggestions
Annie matchup data for League of Legends patch 26.19. The table below shows Annie's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Annie build, runes, laning stats, and early vs late game analysis for that specific matchup.
Other Annie Matchups
Hardest for Annie
Easiest for Annie
Win rate and games for each matchup. Lists are ranked by the edge of the 95% range so small samples cannot top them; matchups with at least 50 games only.
Help us maintain accuracy! If you notice incorrect stats, missing data, or any issues, your feedback directly improves the quality of our data for the entire community.
Annie vs Lissandra FAQ - Patch 26.19
Who wins Annie vs Lissandra?
Current data slightly favors Lissandra, but the sample is too limited for a strong conclusion: Annie wins 39.3% of 28 games (95% range 23.6–57.6%).
What is Annie's win rate against Lissandra?
Annie wins 39.3% of 28 Mid games against Lissandra on patch 26.19 (95% range 23.6–57.6%). Based on both champions' overall Mid win rates, 51.1% would be expected.
Does Annie counter Lissandra?
Not clearly. Annie wins 39.3% of 28 games against Lissandra, and the 95% range (23.6–57.6%) includes 50%, so neither champion reliably counters the other on current data.
Who wins lane, Annie or Lissandra?
There are not enough games with a 15-minute snapshot yet (27) to say who wins lane.
Does Annie outscale Lissandra?
There are too few games of each length to tell yet.
When is Lissandra strongest against Annie?
On current data there is no stage of the game where Lissandra is ahead of Annie beyond the margin of error.
What should Annie build against Lissandra?
There are not enough games for a matchup-specific core, so use Annie's usual Mid core: Shadowflame, Void Staff, Malignance. The biggest change against Lissandra: Rabadon's Deathcap (15.0% usually, 32.1% here).
What runes should Annie use against Lissandra?
Use Annie's usual Electrocute page (Domination + Sorcery); there are too few games for a matchup-specific page. The biggest change against Lissandra: First Strike (1.6% usually, 10.7% here).