Annie - League of Legends Champion
Win Rate
48.6%
Pick Rate
1.8%

Annievs Lissandra

FMageSupport
Patch26.11
Matches776,441
LaneAll Lanes
TierAll Tiers
Last UpdatedJun 5, 2026
MethodologyData Methodology

Annie vs Lissandra is a decisive matchup in LoL patch 26.11. Annie wins with a 53.9% win rate (+7.7%) over Lissandra based on 39 games. Annie holds the advantage in both the early and late game. Below you'll find the best Annie build, runes, laning stats, and strategies for the Annie vs Lissandra matchup.

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Annie Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Annie performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Annie - 53.9% win rate in this matchup
Annie
53.9% WR
VS
Lissandra vs Annie matchup - 46.1% win rate
Lissandra
46.1% WR

Who Wins the Annie vs Lissandra Matchup?

Annie wins the Annie vs Lissandra matchup
Winner
Annie
Matches: 39
53.9%
Win Rate
46.1%
5.9
CS / min
6.5
948
DMG / min
773
11,079
Gold / game
10,883
70
Heal / min
132
470
DMG Mitigated / min
435
0.9
CC / min
1.6
58.8%
Early Game WR
41.2%
50.0%
Late Game WR
50.0%

Annie vs Lissandra Matchup Summary

The Annie vs Lissandra matchup is a decisive matchup in League of Legends ranked play. Based on 39 recent matches analyzed, Annie wins with a 53.9% win rate compared to Lissandra's 46.1%, giving Annie a 7.7 percentage point advantage. Annie dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Lissandra players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Lissandra leads by 0.7s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Annie players can confidently pick into Lissandra and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Lissandra away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Annie vs Lissandra Laning Phase Breakdown

Lissandra wins the laning phase against Annie in League of Legends

Lissandra is favored during the laning phase against Annie, winning 3 out of 5 key stat categories. Lissandra holds advantages in farming, crowd control and sustain, making them the stronger laner in this matchup.

Farming
5.9Annie
6.5Lissandra
Lissandra edges out Annie by 0.6 CS per minute — a moderate farming advantage that adds up to roughly 9 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Lissandra.
Damage
948Annie
773Lissandra
Annie heavily out-damages Lissandra by 175 DMG/min, dominating both short trades and all-in fights. Lissandra should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Annie's sustained damage advantage take over.
Economy
11,079Annie
10,883Lissandra
Annie and Lissandra generate nearly equal gold per game, with just a 196 gold difference. Neither champion has a clear economic advantage, so gold leads will depend on individual play quality, kill participation, and objective contributions.
Utility
0.9Annie
1.6Lissandra
Lissandra provides 0.7 seconds more crowd control per minute than Annie, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Lissandra coordinate with their jungler and control the pace of skirmishes.
Sustain
539Annie
567Lissandra
Annie and Lissandra have comparable sustain profiles, with only 28 HP/min separating their healing and damage mitigation. Neither champion can out-attrition the other in lane, so trades will be decided by burst potential and ability usage rather than sustain.

Best Annie Build Against Lissandra

Spellslinger's Shoes is the optimal boots choice against Lissandra, providing the mobility and stats Annie needs most in this matchup. The top-performing core items for Annie against Lissandra are Shadowflame, Zhonya's Hourglass and Hextech Rocketbelt. This combination gives Annie an effective balance of damage, survivability, and utility for the matchup. This build achieves a solid 50.0% win rate across 4 games, proving it to be a reliable item path when facing Lissandra. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Annie vs Lissandra matchup.

Early Game vs Late Game

Early Game
Annie
58.8%
+17.6% advantage
Annie early game win rateAnnie58.8%
Lissandra early game win rateLissandra41.2%
Late Game
Annie
50.0%
+0.0% advantage
Annie late game win rateAnnie50.0%
Lissandra late game win rateLissandra50.0%

Annie dominates the early game (first 15 minutes) with a commanding 58.8% win rate — a 17.6 percentage point lead over Lissandra. This lopsided early game means Annie can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Late game (25+ minutes) is equally balanced, with Annie at 50.0% win rate — only 0.0 points ahead of Lissandra. Team fight execution and macro play determine the winner at this stage, not champion matchup advantage.

Annie holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Lissandra players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Annie Runes Against Lissandra

Domination rune tree - Annie primary runes vs LissandraDomination
Electrocute - best Annie rune vs LissandraCheap Shot - best Annie rune vs LissandraGrisly Mementos - best Annie rune vs LissandraRelentless Hunter - best Annie rune vs Lissandra
Sorcery rune tree - Annie secondary runes vs LissandraSorcery
Axiom Arcanist - best Annie rune vs LissandraAbsolute Focus - best Annie rune vs Lissandra
66.7% WR

Running Domination primary with Sorcery secondary allows Annie to press their advantage against Lissandra, amplifying the strengths that make this a favorable matchup.


Annie matchup data for League of Legends patch 26.11. The table below shows Annie's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Annie build, runes, laning stats, and early vs late game analysis for that specific matchup.

Annie matchup win rates and stats in League of Legends patch 26.11
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
46.63%1636.090110,99742.9%49.5%
50.41%1235.891111,27746.8%54.1%
43.56%1015.280511,61038.5%46.8%
47.37%956.098011,15546.1%48.8%
39.78%935.886911,17928.6%49.0%
50.00%745.791511,17850.0%50.0%
49.32%735.387011,07943.8%53.7%
38.03%715.686510,26941.2%35.1%
47.14%705.289011,68541.7%50.0%
42.03%695.881011,31130.8%48.8%
52.31%655.491511,17450.0%53.9%
59.32%595.391711,91052.4%63.2%
51.79%565.298211,64140.0%61.3%
43.40%536.195211,67538.1%46.9%
40.38%525.57329,64136.4%47.4%
35.29%515.885111,57127.8%39.4%
50.00%505.581810,80848.0%52.0%
43.75%485.687210,95839.1%48.0%
40.43%475.89019,13743.8%33.3%
48.94%475.497112,63738.9%55.2%
44.19%435.889011,31140.0%47.8%
48.84%436.177310,57563.6%33.3%
58.14%435.986011,45161.9%54.5%
57.50%406.490911,94346.7%64.0%
53.85%395.994811,07958.8%50.0%
46.15%395.093211,80850.0%43.5%
55.26%385.798913,30662.5%53.3%
56.76%375.990310,95452.6%61.1%
61.11%365.186412,16466.7%59.3%
41.67%365.491310,73025.0%55.0%
51.61%315.884210,31347.4%58.3%
30.00%305.87739,85837.5%21.4%
41.38%295.598410,34037.5%46.1%
42.86%284.886211,81133.3%47.4%
46.43%285.991311,75350.0%44.4%
42.31%264.183911,25741.7%42.9%
53.85%265.89209,34557.1%50.0%
44.00%253.17429,60640.0%46.7%
36.00%254.978910,94241.7%30.8%
63.64%225.779110,67669.2%55.6%
68.18%225.71,08112,12850.0%78.6%
45.45%225.587710,94540.0%50.0%
40.91%225.98829,32520.0%58.3%
36.36%222.377011,96340.0%35.3%
65.00%205.987210,94555.6%72.7%
47.37%195.685411,06425.0%63.6%
42.11%191.67479,54850.0%38.5%
56.25%162.369511,37566.7%50.0%
46.67%154.691310,73550.0%44.4%
60.00%156.21,02812,49960.0%60.0%
28.57%146.39779,4730.0%66.7%
61.54%131.562810,47166.7%57.1%
38.46%136.11,02711,94550.0%33.3%
38.46%135.11,08911,28550.0%28.6%
61.54%131.26969,80675.0%55.6%
63.64%113.56969,58550.0%80.0%
54.55%116.087710,89457.1%50.0%
63.64%111.882510,70550.0%71.4%
54.55%112.17129,97480.0%33.3%
60.00%106.782211,00966.7%50.0%
40.00%101.663811,0390.0%57.1%
60.00%106.598413,174100.0%50.0%
50.00%105.772610,23450.0%50.0%
40.00%104.894812,31933.3%42.9%
60.00%104.91,03613,4940.0%75.0%
66.67%95.794513,13466.7%66.7%
66.67%95.686610,998100.0%50.0%
33.33%95.578211,7800.0%50.0%
66.67%91.85909,98833.3%83.3%
66.67%91.86209,682100.0%57.1%
66.67%96.091410,55666.7%66.7%
25.00%81.57549,4160.0%33.3%
50.00%81.65109,81966.7%40.0%
50.00%85.384611,04150.0%50.0%
28.57%75.81,04913,572100.0%16.7%
57.14%76.280310,91850.0%66.7%
71.43%71.26878,93483.3%0.0%
71.43%75.31,05013,583100.0%60.0%
16.67%65.21,06714,7020.0%16.7%
66.67%61.35269,7190.0%66.7%
66.67%67.01,00412,47966.7%66.7%
16.67%64.576710,99450.0%0.0%
66.67%65.71,07012,75650.0%75.0%
0.00%64.18248,4890.0%0.0%
60.00%56.397310,68250.0%100.0%
40.00%51.56399,29325.0%100.0%
40.00%54.583410,63433.3%50.0%
40.00%51.96089,73050.0%33.3%
80.00%57.01,06210,09675.0%100.0%
20.00%55.87989,6400.0%50.0%
80.00%54.989312,74566.7%100.0%
40.00%51.65858,47133.3%50.0%
60.00%55.291612,2620.0%75.0%

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Annie vs Lissandra - Frequently Asked Questions

How does Annie do against Lissandra in League of Legends?

Annie wins the Annie vs Lissandra matchup with a 53.9% win rate compared to Lissandra's 46.1%, a 7.7 percentage point difference. This data is based on 39 recent ranked games in patch 26.11.

How does Annie do against Lissandra in the early game?

In the early game, Annie has the advantage against Lissandra with a 58.8% win rate versus 41.2%. Annie players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Annie do against Lissandra in the late game?

In the late game, Annie takes over the Annie vs Lissandra matchup with a 50.0% win rate compared to 50.0%. Annie scales better into team fights and objective contests after 25 minutes.

Who wins the Annie vs Lissandra matchup?

Annie wins the matchup against Lissandra with a 53.9% win rate in League of Legends patch 26.11. The 7.7 percentage point advantage means Annie is significantly favored in this lane matchup based on 39 games analyzed.

What is the best Annie build against Lissandra?

The best Annie build against Lissandra includes Shadowflame, Zhonya's Hourglass, Hextech Rocketbelt with Spellslinger's Shoes. This build achieves a 50.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Annie runes against Lissandra?

The best Annie runes against Lissandra use the Domination primary tree with Sorcery secondary. This rune setup achieves a 66.7% win rate in the Annie vs Lissandra matchup. See the full rune breakdown in the matchup comparison above.

Does Annie counter Lissandra?

Yes, Annie has a favorable matchup against Lissandra with a 53.9% win rate. Annie strongly counters Lissandra in lane based on current patch 26.11 data.

How do I play Annie against Lissandra?

When playing Annie against Lissandra, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.