Annie - League of Legends Champion
Win Rate
53.7%
Pick Rate
1.3%

Annievs Lissandra

SMageSupport
Patch26.14
Matches226,800
LaneAll Lanes
TierAll Tiers
Last UpdatedJul 21, 2026
MethodologyData Methodology

Annie vs Lissandra is a decisive matchup in LoL patch 26.14. Annie wins with a 66.7% win rate (+33.3%) over Lissandra based on 6 games. Annie holds the advantage in both the early and late game. Below you'll find the best Annie build, runes, laning stats, and strategies for the Annie vs Lissandra matchup.

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Annie Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Annie performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Annie - 66.7% win rate in this matchup
Annie
66.7% WR
VS
Lissandra vs Annie matchup - 33.3% win rate
Lissandra
33.3% WR

Who Wins the Annie vs Lissandra Matchup?

Annie wins the Annie vs Lissandra matchup
Winner
Annie
Matches: 6
66.7%
Win Rate
33.3%
5.7
CS / min
6.7
1,090
DMG / min
1,027
14,481
Gold / game
15,069
90
Heal / min
152
438
DMG Mitigated / min
566
1.0
CC / min
2.0
0.0%
Early Game WR
0.0%
66.7%
Late Game WR
33.3%

Annie vs Lissandra Matchup Summary

The Annie vs Lissandra matchup is a decisive matchup in League of Legends ranked play. Based on 6 recent matches analyzed, Annie wins with a 66.7% win rate compared to Lissandra's 33.3%, giving Annie a 33.3 percentage point advantage. Annie dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Lissandra players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Lissandra leads by 1.0s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Annie players can confidently pick into Lissandra and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Lissandra away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Annie vs Lissandra Laning Phase Breakdown

Lissandra wins the laning phase against Annie in League of Legends

Lissandra is favored during the laning phase against Annie, winning 4 out of 5 key stat categories. Lissandra holds advantages in farming, gold income, crowd control and sustain, making them the stronger laner in this matchup.

Farming
5.7Annie
6.7Lissandra
Lissandra significantly out-farms Annie by 1.0 CS per minute, accumulating an estimated 16 CS lead by mid game. This substantial farming gap gives Lissandra a major gold advantage and earlier item completions. Annie players should prioritize wave management techniques like freezing near tower and using abilities efficiently to minimize the deficit.
Damage
1,090Annie
1,027Lissandra
Annie deals 63 more champion damage per minute than Lissandra. While noticeable in extended trades, this gap can be offset by Lissandra choosing favorable fight windows, such as engaging when Annie's key abilities are on cooldown or trading immediately after dodging a skillshot.
Economy
14,481Annie
15,069Lissandra
Lissandra earns 588 more gold per game than Annie, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Lissandra slightly faster item completions.
Utility
1.0Annie
2.0Lissandra
Lissandra brings significantly more crowd control than Annie, with 1.0 more seconds of CC per minute. This large utility gap makes Lissandra far more valuable in setting up jungle ganks, controlling objectives, and locking down targets in team fights. Annie should invest in tenacity and position carefully to avoid being chain-CC'd.
Sustain
528Annie
718Lissandra
Lissandra vastly out-sustains Annie, healing and mitigating 190 more damage per minute. This massive durability gap means Lissandra can absorb significant punishment and remain in lane while Annie is forced to recall. Building grievous wounds early is essential for Annie, and focusing on burst trade patterns rather than sustained fights is critical.

Best Annie Build Against Lissandra

Spellslinger's Shoes is the optimal boots choice against Lissandra, providing the mobility and stats Annie needs most in this matchup. The top-performing core items for Annie against Lissandra are Stormsurge, Shadowflame and Malignance. This combination gives Annie an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 2 games — well above average and making it the top item path against Lissandra. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Annie vs Lissandra matchup.

Early Game vs Late Game

Early Game
Annie
0.0%
+0.0% advantage
Annie early game win rateAnnie0.0%
Lissandra early game win rateLissandra0.0%
Late Game
Annie
66.7%
+33.3% advantage
Annie late game win rateAnnie66.7%
Lissandra late game win rateLissandra33.3%

The early game (first 15 minutes) is a toss-up between Annie and Lissandra, with Annie holding a razor-thin 0.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.

Annie is far superior in the late game (25+ minutes), boasting a 66.7% win rate — 33.3 points above Lissandra. Extended games heavily favor Annie, whose kit and scaling make them a dominant force in team fights and objective control.

Annie holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Lissandra players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Annie Runes Against Lissandra

Domination rune tree - Annie primary runes vs LissandraDomination
Electrocute - best Annie rune vs LissandraCheap Shot - best Annie rune vs LissandraGrisly Mementos - best Annie rune vs LissandraRelentless Hunter - best Annie rune vs Lissandra
Sorcery rune tree - Annie secondary runes vs LissandraSorcery
Absolute Focus - best Annie rune vs LissandraAxiom Arcanist - best Annie rune vs Lissandra
66.7% WR

Running Domination primary with Sorcery secondary allows Annie to press their advantage against Lissandra, amplifying the strengths that make this a favorable matchup.


Annie matchup data for League of Legends patch 26.14. The table below shows Annie's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Annie build, runes, laning stats, and early vs late game analysis for that specific matchup.

Annie matchup win rates and stats in League of Legends patch 26.14
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
65.12%435.693911,49761.1%68.0%
35.29%346.08989,96922.2%50.0%
50.00%265.393911,07341.7%57.1%
45.00%206.08309,83330.0%60.0%
80.00%205.498012,11571.4%84.6%
47.37%195.21,03111,71912.5%72.7%
50.00%185.391911,69050.0%50.0%
61.11%185.590411,03760.0%61.5%
43.75%164.87189,86833.3%50.0%
38.46%135.272311,05433.3%40.0%
46.15%135.71,06714,471100.0%41.7%
41.67%125.469210,35928.6%60.0%
50.00%126.290111,8260.0%66.7%
58.33%124.68859,13383.3%33.3%
72.73%116.11,17612,37650.0%85.7%
60.00%105.31,03610,27050.0%66.7%
40.00%105.783311,7210.0%50.0%
44.44%95.492410,01266.7%33.3%
66.67%94.975711,67275.0%60.0%
66.67%95.490110,33966.7%66.7%
50.00%85.180110,91150.0%50.0%
50.00%84.57909,94966.7%40.0%
57.14%75.274610,22666.7%50.0%
28.57%73.273110,07033.3%25.0%
85.71%75.79709,82875.0%100.0%
16.67%64.68139,7860.0%20.0%
66.67%65.71,09014,4810.0%66.7%
50.00%65.698311,4960.0%75.0%
66.67%65.294913,5460.0%66.7%
83.33%64.81,1017,37866.7%100.0%
50.00%65.782411,023100.0%40.0%
40.00%55.795713,21050.0%33.3%
20.00%53.88048,8230.0%25.0%
40.00%55.479913,0040.0%50.0%
75.00%47.11,15312,76850.0%100.0%

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Annie vs Lissandra - Frequently Asked Questions

How does Annie do against Lissandra in League of Legends?

Annie wins the Annie vs Lissandra matchup with a 66.7% win rate compared to Lissandra's 33.3%, a 33.3 percentage point difference. This data is based on 6 recent ranked games in patch 26.14.

How does Annie do against Lissandra in the early game?

In the early game, Annie has the advantage against Lissandra with a 0.0% win rate versus 0.0%. Annie players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Annie do against Lissandra in the late game?

In the late game, Annie takes over the Annie vs Lissandra matchup with a 66.7% win rate compared to 33.3%. Annie scales better into team fights and objective contests after 25 minutes.

Who wins the Annie vs Lissandra matchup?

Annie wins the matchup against Lissandra with a 66.7% win rate in League of Legends patch 26.14. The 33.3 percentage point advantage means Annie is significantly favored in this lane matchup based on 6 games analyzed.

What is the best Annie build against Lissandra?

The best Annie build against Lissandra includes Stormsurge, Shadowflame, Malignance with Spellslinger's Shoes. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Annie runes against Lissandra?

The best Annie runes against Lissandra use the Domination primary tree with Sorcery secondary. This rune setup achieves a 66.7% win rate in the Annie vs Lissandra matchup. See the full rune breakdown in the matchup comparison above.

Does Annie counter Lissandra?

Yes, Annie has a favorable matchup against Lissandra with a 66.7% win rate. Annie strongly counters Lissandra in lane based on current patch 26.14 data.

How do I play Annie against Lissandra?

When playing Annie against Lissandra, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.