Annie - League of Legends Champion
Win Rate
49.5%
Pick Rate
1.8%

Annievs Vayne

CMageSupport
Patch26.11
Matches776,441
LaneAll Lanes
TierAll Tiers
Last UpdatedJun 10, 2026
MethodologyData Methodology

Annie vs Vayne is a decisive matchup in LoL patch 26.11. Annie wins with a 71.4% win rate (+42.9%) over Vayne based on 7 games. Annie holds the advantage in both the early and late game. Below you'll find the best Annie build, runes, laning stats, and strategies for the Annie vs Vayne matchup.

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Annie Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Annie performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Annie - 71.4% win rate in this matchup
Annie
71.4% WR
VS
Vayne vs Annie matchup - 28.6% win rate
Vayne
28.6% WR

Who Wins the Annie vs Vayne Matchup?

Annie wins the Annie vs Vayne matchup
Winner
Annie
Matches: 7
71.4%
Win Rate
28.6%
5.3
CS / min
4.5
1,050
DMG / min
676
13,583
Gold / game
12,046
73
Heal / min
162
546
DMG Mitigated / min
494
1.1
CC / min
0.4
100.0%
Early Game WR
0.0%
60.0%
Late Game WR
40.0%

Annie vs Vayne Matchup Summary

The Annie vs Vayne matchup is a decisive matchup in League of Legends ranked play. Based on 7 recent matches analyzed, Annie wins with a 71.4% win rate compared to Vayne's 28.6%, giving Annie a 42.9 percentage point advantage. Annie dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Vayne players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Annie leads by 0.7s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Annie players can confidently pick into Vayne and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Vayne away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Annie vs Vayne Laning Phase Breakdown

Annie wins the laning phase against Vayne in League of Legends

Annie is favored during the laning phase against Vayne, winning 4 out of 5 key stat categories. Annie holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.

Farming
5.3Annie
4.5Vayne
Annie significantly out-farms Vayne by 0.8 CS per minute, accumulating an estimated 13 CS lead by mid game. This substantial farming gap gives Annie a major gold advantage and earlier item completions. Vayne players should prioritize wave management techniques like freezing near tower and using abilities efficiently to minimize the deficit.
Damage
1,050Annie
676Vayne
Annie heavily out-damages Vayne by 374 DMG/min, dominating both short trades and all-in fights. Vayne should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Annie's sustained damage advantage take over.
Economy
13,583Annie
12,046Vayne
Annie generates a commanding 1,537 more gold per game than Vayne. This substantial economic advantage means Annie consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Vayne should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
1.1Annie
0.4Vayne
Annie provides 0.7 seconds more crowd control per minute than Vayne, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Annie coordinate with their jungler and control the pace of skirmishes.
Sustain
619Annie
656Vayne
Annie and Vayne have comparable sustain profiles, with only 37 HP/min separating their healing and damage mitigation. Neither champion can out-attrition the other in lane, so trades will be decided by burst potential and ability usage rather than sustain.

Best Annie Build Against Vayne

Spellslinger's Shoes is the optimal boots choice against Vayne, providing the mobility and stats Annie needs most in this matchup. The top-performing core items for Annie against Vayne are Stormsurge, Shadowflame and Zhonya's Hourglass. This combination gives Annie an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 2 games — well above average and making it the top item path against Vayne. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Annie vs Vayne matchup.

Early Game vs Late Game

Early Game
Annie
100.0%
+100.0% advantage
Annie early game win rateAnnie100.0%
Vayne early game win rateVayne0.0%
Late Game
Annie
60.0%
+20.0% advantage
Annie late game win rateAnnie60.0%
Vayne late game win rateVayne40.0%

Annie dominates the early game (first 15 minutes) with a commanding 100.0% win rate — a 100.0 percentage point lead over Vayne. This lopsided early game means Annie can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Annie is far superior in the late game (25+ minutes), boasting a 60.0% win rate — 20.0 points above Vayne. Extended games heavily favor Annie, whose kit and scaling make them a dominant force in team fights and objective control.

Annie holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Vayne players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Annie Runes Against Vayne

Sorcery rune tree - Annie primary runes vs VayneSorcery
Summon Aery - best Annie rune vs VayneAxiom Arcanist - best Annie rune vs VayneTranscendence - best Annie rune vs VayneScorch - best Annie rune vs Vayne
Precision rune tree - Annie secondary runes vs VaynePrecision
Cut Down - best Annie rune vs VaynePresence of Mind - best Annie rune vs Vayne
100.0% WR

Running Sorcery primary with Precision secondary allows Annie to press their advantage against Vayne, amplifying the strengths that make this a favorable matchup.


Annie matchup data for League of Legends patch 26.11. The table below shows Annie's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Annie build, runes, laning stats, and early vs late game analysis for that specific matchup.

Annie matchup win rates and stats in League of Legends patch 26.11
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
46.63%1636.090110,99742.9%49.5%
50.41%1235.891111,27746.8%54.1%
43.56%1015.280511,61038.5%46.8%
47.37%956.098011,15546.1%48.8%
39.78%935.886911,17928.6%49.0%
50.00%745.791511,17850.0%50.0%
49.32%735.387011,07943.8%53.7%
38.03%715.686510,26941.2%35.1%
47.14%705.289011,68541.7%50.0%
42.03%695.881011,31130.8%48.8%
52.31%655.491511,17450.0%53.9%
59.32%595.391711,91052.4%63.2%
51.79%565.298211,64140.0%61.3%
43.40%536.195211,67538.1%46.9%
40.38%525.57329,64136.4%47.4%
35.29%515.885111,57127.8%39.4%
50.00%505.581810,80848.0%52.0%
43.75%485.687210,95839.1%48.0%
40.43%475.89019,13743.8%33.3%
48.94%475.497112,63738.9%55.2%
44.19%435.889011,31140.0%47.8%
48.84%436.177310,57563.6%33.3%
58.14%435.986011,45161.9%54.5%
57.50%406.490911,94346.7%64.0%
53.85%395.994811,07958.8%50.0%
46.15%395.093211,80850.0%43.5%
55.26%385.798913,30662.5%53.3%
56.76%375.990310,95452.6%61.1%
61.11%365.186412,16466.7%59.3%
41.67%365.491310,73025.0%55.0%
51.61%315.884210,31347.4%58.3%
30.00%305.87739,85837.5%21.4%
41.38%295.598410,34037.5%46.1%
42.86%284.886211,81133.3%47.4%
46.43%285.991311,75350.0%44.4%
42.31%264.183911,25741.7%42.9%
53.85%265.89209,34557.1%50.0%
44.00%253.17429,60640.0%46.7%
36.00%254.978910,94241.7%30.8%
63.64%225.779110,67669.2%55.6%
68.18%225.71,08112,12850.0%78.6%
45.45%225.587710,94540.0%50.0%
40.91%225.98829,32520.0%58.3%
36.36%222.377011,96340.0%35.3%
65.00%205.987210,94555.6%72.7%
47.37%195.685411,06425.0%63.6%
42.11%191.67479,54850.0%38.5%
56.25%162.369511,37566.7%50.0%
46.67%154.691310,73550.0%44.4%
60.00%156.21,02812,49960.0%60.0%
28.57%146.39779,4730.0%66.7%
61.54%131.562810,47166.7%57.1%
38.46%136.11,02711,94550.0%33.3%
38.46%135.11,08911,28550.0%28.6%
61.54%131.26969,80675.0%55.6%
63.64%113.56969,58550.0%80.0%
54.55%116.087710,89457.1%50.0%
63.64%111.882510,70550.0%71.4%
54.55%112.17129,97480.0%33.3%
60.00%106.782211,00966.7%50.0%
40.00%101.663811,0390.0%57.1%
60.00%106.598413,174100.0%50.0%
50.00%105.772610,23450.0%50.0%
40.00%104.894812,31933.3%42.9%
60.00%104.91,03613,4940.0%75.0%
66.67%95.794513,13466.7%66.7%
66.67%95.686610,998100.0%50.0%
33.33%95.578211,7800.0%50.0%
66.67%91.85909,98833.3%83.3%
66.67%91.86209,682100.0%57.1%
66.67%96.091410,55666.7%66.7%
25.00%81.57549,4160.0%33.3%
50.00%81.65109,81966.7%40.0%
50.00%85.384611,04150.0%50.0%
28.57%75.81,04913,572100.0%16.7%
57.14%76.280310,91850.0%66.7%
71.43%71.26878,93483.3%0.0%
71.43%75.31,05013,583100.0%60.0%
16.67%65.21,06714,7020.0%16.7%
66.67%61.35269,7190.0%66.7%
66.67%67.01,00412,47966.7%66.7%
16.67%64.576710,99450.0%0.0%
66.67%65.71,07012,75650.0%75.0%
0.00%64.18248,4890.0%0.0%
60.00%56.397310,68250.0%100.0%
40.00%51.56399,29325.0%100.0%
40.00%54.583410,63433.3%50.0%
40.00%51.96089,73050.0%33.3%
80.00%57.01,06210,09675.0%100.0%
20.00%55.87989,6400.0%50.0%
80.00%54.989312,74566.7%100.0%
40.00%51.65858,47133.3%50.0%
60.00%55.291612,2620.0%75.0%

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Annie vs Vayne - Frequently Asked Questions

How does Annie do against Vayne in League of Legends?

Annie wins the Annie vs Vayne matchup with a 71.4% win rate compared to Vayne's 28.6%, a 42.9 percentage point difference. This data is based on 7 recent ranked games in patch 26.11.

How does Annie do against Vayne in the early game?

In the early game, Annie has the advantage against Vayne with a 100.0% win rate versus 0.0%. Annie players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Annie do against Vayne in the late game?

In the late game, Annie takes over the Annie vs Vayne matchup with a 60.0% win rate compared to 40.0%. Annie scales better into team fights and objective contests after 25 minutes.

Who wins the Annie vs Vayne matchup?

Annie wins the matchup against Vayne with a 71.4% win rate in League of Legends patch 26.11. The 42.9 percentage point advantage means Annie is significantly favored in this lane matchup based on 7 games analyzed.

What is the best Annie build against Vayne?

The best Annie build against Vayne includes Stormsurge, Shadowflame, Zhonya's Hourglass with Spellslinger's Shoes. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Annie runes against Vayne?

The best Annie runes against Vayne use the Sorcery primary tree with Precision secondary. This rune setup achieves a 100.0% win rate in the Annie vs Vayne matchup. See the full rune breakdown in the matchup comparison above.

Does Annie counter Vayne?

Yes, Annie has a favorable matchup against Vayne with a 71.4% win rate. Annie strongly counters Vayne in lane based on current patch 26.11 data.

How do I play Annie against Vayne?

When playing Annie against Vayne, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.