Annievs Vayne
Annie vs Vayne is a decisive matchup in LoL patch 26.5. Annie wins with a 83.3% win rate (+66.7%) over Vayne based on 6 games. Annie holds the advantage in both the early and late game. Below you'll find the best Annie build, runes, laning stats, and strategies for the Annie vs Vayne matchup.
Annie Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Annie performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Vayne(83.3%)Who Wins the Annie vs Vayne Matchup?
Annie vs Vayne Matchup Summary
The Annie vs Vayne matchup is a decisive matchup in League of Legends ranked play. Based on 6 recent matches analyzed, Annie wins with a 83.3% win rate compared to Vayne's 16.7%, giving Annie a 66.7 percentage point advantage. Annie dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Vayne players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Annie leads by 0.9s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Annie players can confidently pick into Vayne and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Vayne away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Annie vs Vayne Laning Phase Breakdown
Annie is favored during the laning phase against Vayne, winning 3 out of 5 key stat categories. Annie holds advantages in damage, gold income and crowd control, making them the stronger laner in this matchup.
Best Annie Build Against Vayne
Sorcerer's Shoes is the optimal boots choice against Vayne, providing the mobility and stats Annie needs most in this matchup. The top-performing core items for Annie against Vayne are Shadowflame, Malignance and Mejai's Soulstealer. This combination gives Annie an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Vayne. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Annie vs Vayne matchup.
Early Game vs Late Game
Annie100.0%Vayne0.0%Annie50.0%Vayne50.0%Annie dominates the early game (first 15 minutes) with a commanding 100.0% win rate — a 100.0 percentage point lead over Vayne. This lopsided early game means Annie can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Late game (25+ minutes) is equally balanced, with Annie at 50.0% win rate — only 0.0 points ahead of Vayne. Team fight execution and macro play determine the winner at this stage, not champion matchup advantage.
Annie holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Vayne players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.
Best Annie Runes Against Vayne
Domination
Sorcery
Running Domination primary with Sorcery secondary allows Annie to press their advantage against Vayne, amplifying the strengths that make this a favorable matchup.
Annie matchup data for League of Legends patch 26.5. The table below shows Annie's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Annie build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 35.24% | 105 | 6.0 | 937 | 11,012 | 26.2% | 41.3% | |
| 55.07% | 69 | 6.0 | 876 | 10,883 | 42.1% | 71.0% | |
| 34.69% | 49 | 6.2 | 823 | 11,102 | 20.0% | 44.8% | |
| 42.22% | 45 | 6.1 | 858 | 11,200 | 42.1% | 42.3% | |
| 50.00% | 42 | 5.7 | 966 | 12,341 | 35.7% | 57.1% | |
| 63.41% | 41 | 5.6 | 975 | 12,330 | 71.4% | 59.3% | |
| 66.67% | 39 | 6.0 | 994 | 11,593 | 71.4% | 61.1% | |
| 55.56% | 36 | 4.7 | 820 | 11,286 | 72.7% | 48.0% | |
| 46.67% | 30 | 5.3 | 854 | 11,238 | 18.8% | 78.6% | |
| 46.43% | 28 | 5.6 | 807 | 10,977 | 25.0% | 75.0% | |
| 57.14% | 28 | 6.2 | 782 | 11,111 | 63.6% | 52.9% | |
| 61.54% | 26 | 4.6 | 746 | 11,561 | 66.7% | 58.8% | |
| 73.08% | 26 | 5.9 | 978 | 12,772 | 70.0% | 75.0% | |
| 57.69% | 26 | 5.4 | 919 | 11,025 | 46.1% | 69.2% | |
| 44.00% | 25 | 5.9 | 923 | 11,252 | 38.5% | 50.0% | |
| 41.67% | 24 | 6.2 | 798 | 10,803 | 27.3% | 53.9% | |
| 45.83% | 24 | 5.4 | 846 | 11,266 | 33.3% | 53.3% | |
| 47.62% | 21 | 6.2 | 1,074 | 12,190 | 40.0% | 50.0% | |
| 61.90% | 21 | 5.7 | 982 | 12,578 | 50.0% | 69.2% | |
| 61.90% | 21 | 5.8 | 912 | 12,286 | 66.7% | 58.3% | |
| 57.14% | 21 | 6.1 | 918 | 10,331 | 58.3% | 55.6% | |
| 40.00% | 20 | 5.5 | 957 | 12,254 | 28.6% | 46.1% | |
| 42.11% | 19 | 5.8 | 838 | 9,979 | 33.3% | 57.1% | |
| 44.44% | 18 | 4.2 | 844 | 10,259 | 50.0% | 37.5% | |
| 50.00% | 18 | 6.2 | 844 | 10,294 | 46.1% | 60.0% | |
| 58.82% | 17 | 5.7 | 1,054 | 11,635 | 71.4% | 50.0% | |
| 58.82% | 17 | 5.5 | 1,100 | 12,370 | 83.3% | 45.5% | |
| 43.75% | 16 | 1.4 | 521 | 8,417 | 40.0% | 50.0% | |
| 62.50% | 16 | 2.9 | 645 | 11,399 | 57.1% | 66.7% | |
| 37.50% | 16 | 1.4 | 680 | 10,620 | 16.7% | 50.0% | |
| 73.33% | 15 | 5.3 | 857 | 11,460 | 85.7% | 62.5% | |
| 73.33% | 15 | 3.4 | 737 | 10,316 | 83.3% | 66.7% | |
| 50.00% | 14 | 5.7 | 1,062 | 13,123 | 33.3% | 62.5% | |
| 64.29% | 14 | 5.8 | 779 | 11,479 | 66.7% | 60.0% | |
| 35.71% | 14 | 1.4 | 611 | 9,184 | 16.7% | 50.0% | |
| 71.43% | 14 | 5.2 | 958 | 11,620 | 62.5% | 83.3% | |
| 57.14% | 14 | 5.4 | 987 | 11,706 | 66.7% | 50.0% | |
| 50.00% | 12 | 1.6 | 828 | 11,668 | 60.0% | 42.9% | |
| 63.64% | 11 | 6.0 | 954 | 13,649 | 100.0% | 60.0% | |
| 27.27% | 11 | 6.1 | 874 | 11,882 | 25.0% | 28.6% | |
| 60.00% | 10 | 6.7 | 785 | 9,861 | 62.5% | 50.0% | |
| 44.44% | 9 | 4.1 | 792 | 10,977 | 0.0% | 66.7% | |
| 33.33% | 9 | 2.0 | 742 | 10,596 | 25.0% | 40.0% | |
| 44.44% | 9 | 3.3 | 786 | 8,851 | 50.0% | 40.0% | |
| 33.33% | 9 | 5.6 | 1,118 | 11,361 | 25.0% | 40.0% | |
| 55.56% | 9 | 5.8 | 1,173 | 12,074 | 50.0% | 57.1% | |
| 37.50% | 8 | 3.1 | 617 | 10,630 | 33.3% | 40.0% | |
| 62.50% | 8 | 6.4 | 1,203 | 13,200 | 50.0% | 75.0% | |
| 62.50% | 8 | 4.8 | 1,180 | 12,623 | 66.7% | 60.0% | |
| 37.50% | 8 | 5.6 | 941 | 11,908 | 50.0% | 25.0% | |
| 50.00% | 8 | 5.0 | 965 | 11,267 | 33.3% | 60.0% | |
| 37.50% | 8 | 1.6 | 571 | 8,505 | 50.0% | 25.0% | |
| 42.86% | 7 | 4.0 | 929 | 9,860 | 66.7% | 25.0% | |
| 42.86% | 7 | 6.4 | 1,122 | 13,597 | 50.0% | 40.0% | |
| 14.29% | 7 | 1.0 | 454 | 9,048 | 0.0% | 25.0% | |
| 28.57% | 7 | 2.1 | 591 | 8,394 | 25.0% | 33.3% | |
| 28.57% | 7 | 6.7 | 726 | 8,639 | 20.0% | 50.0% | |
| 71.43% | 7 | 5.5 | 1,028 | 14,528 | 100.0% | 66.7% | |
| 66.67% | 6 | 1.3 | 660 | 10,473 | 100.0% | 50.0% | |
| 33.33% | 6 | 4.7 | 906 | 12,674 | 100.0% | 20.0% | |
| 33.33% | 6 | 5.9 | 902 | 11,242 | 25.0% | 50.0% | |
| 16.67% | 6 | 5.9 | 940 | 11,632 | 0.0% | 25.0% | |
| 83.33% | 6 | 6.1 | 1,000 | 12,399 | 100.0% | 50.0% | |
| 50.00% | 6 | 1.6 | 672 | 9,592 | 33.3% | 66.7% | |
| 33.33% | 6 | 2.3 | 823 | 8,547 | 25.0% | 50.0% | |
| 33.33% | 6 | 5.7 | 938 | 12,197 | 100.0% | 0.0% | |
| 33.33% | 6 | 2.5 | 689 | 9,136 | 40.0% | 0.0% | |
| 40.00% | 5 | 2.5 | 701 | 12,371 | 0.0% | 40.0% | |
| 40.00% | 5 | 1.2 | 591 | 10,909 | 50.0% | 33.3% | |
| 40.00% | 5 | 3.8 | 785 | 10,434 | 33.3% | 50.0% | |
| 60.00% | 5 | 3.8 | 1,020 | 14,301 | 100.0% | 50.0% | |
| 40.00% | 5 | 1.6 | 648 | 10,452 | 0.0% | 40.0% | |
| 60.00% | 5 | 1.2 | 537 | 9,948 | 100.0% | 50.0% | |
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Annie vs Vayne - Frequently Asked Questions
How does Annie do against Vayne in League of Legends?
Annie wins the Annie vs Vayne matchup with a 83.3% win rate compared to Vayne's 16.7%, a 66.7 percentage point difference. This data is based on 6 recent ranked games in patch 26.5.
How does Annie do against Vayne in the early game?
In the early game, Annie has the advantage against Vayne with a 100.0% win rate versus 0.0%. Annie players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Annie do against Vayne in the late game?
In the late game, Annie takes over the Annie vs Vayne matchup with a 50.0% win rate compared to 50.0%. Annie scales better into team fights and objective contests after 25 minutes.
Who wins the Annie vs Vayne matchup?
Annie wins the matchup against Vayne with a 83.3% win rate in League of Legends patch 26.5. The 66.7 percentage point advantage means Annie is significantly favored in this lane matchup based on 6 games analyzed.
What is the best Annie build against Vayne?
The best Annie build against Vayne includes Shadowflame, Malignance, Mejai's Soulstealer with Sorcerer's Shoes. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.
What are the best Annie runes against Vayne?
The best Annie runes against Vayne use the Domination primary tree with Sorcery secondary. This rune setup achieves a 100.0% win rate in the Annie vs Vayne matchup. See the full rune breakdown in the matchup comparison above.
Does Annie counter Vayne?
Yes, Annie has a favorable matchup against Vayne with a 83.3% win rate. Annie strongly counters Vayne in lane based on current patch 26.5 data.
How do I play Annie against Vayne?
When playing Annie against Vayne, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.