Annie - League of Legends Champion
Win Rate
50.0%
Pick Rate
1.4%

Annievs Vayne

CMageSupport
Patch26.7
Matches949,984
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 26, 2026
MethodologyData Methodology

Annie vs Vayne is a very close matchup in LoL patch 26.7. Annie wins with a 50.0% win rate (+0.0%) over Vayne based on 6 games. Annie holds the advantage in both the early and late game. Below you'll find the best Annie build, runes, laning stats, and strategies for the Annie vs Vayne matchup.

Annie Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Annie performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Vayne - 50.0% win rateVayne(50.0%)
Annie - 50.0% win rate in this matchup
Annie
50.0% WR
VS
Vayne vs Annie matchup - 50.0% win rate
Vayne
50.0% WR

Who Wins the Annie vs Vayne Matchup?

Annie wins the Annie vs Vayne matchup
Winner
Annie
Matches: 6
50.0%
Win Rate
50.0%
5.4
CS / min
5.7
1,195
DMG / min
762
14,593
Gold / game
13,182
89
Heal / min
217
560
DMG Mitigated / min
534
1.2
CC / min
0.3
50.0%
Early Game WR
50.0%
50.0%
Late Game WR
50.0%

Annie vs Vayne Matchup Summary

The Annie vs Vayne matchup is essentially a coin-flip matchup in League of Legends ranked play. Based on 6 recent matches analyzed, Annie wins with a 50.0% win rate compared to Vayne's 50.0%, giving Annie a 0.0 percentage point advantage. Annie holds a slight edge in both the early and late game, but the margins are thin enough that individual skill and jungle attention will often determine the outcome. Vayne can still find windows through outplays and team coordination. The most significant statistical gap is in crowd control, where Annie leads by 0.8s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Annie has a statistical edge, but the margin is close enough that respecting Vayne's strengths is important. Trade when cooldowns are favorable, track the enemy jungler, and build toward your strongest item spikes to convert the slight advantage into a decisive lead. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Annie vs Vayne Laning Phase Breakdown

Annie wins the laning phase against Vayne in League of Legends

Annie is favored during the laning phase against Vayne, winning 3 out of 5 key stat categories. Annie holds advantages in damage, gold income and crowd control, making them the stronger laner in this matchup.

Farming
5.4Annie
5.7Vayne
Annie and Vayne farm at nearly identical rates in this matchup, with only a 0.3 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
1,195Annie
762Vayne
Annie heavily out-damages Vayne by 433 DMG/min, dominating both short trades and all-in fights. Vayne should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Annie's sustained damage advantage take over.
Economy
14,593Annie
13,182Vayne
Annie generates a commanding 1,410 more gold per game than Vayne. This substantial economic advantage means Annie consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Vayne should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
1.2Annie
0.3Vayne
Annie brings significantly more crowd control than Vayne, with 0.8 more seconds of CC per minute. This large utility gap makes Annie far more valuable in setting up jungle ganks, controlling objectives, and locking down targets in team fights. Vayne should invest in tenacity and position carefully to avoid being chain-CC'd.
Sustain
649Annie
751Vayne
Vayne heals and mitigates 102 more damage per minute than Annie, providing moderate extra durability. This sustain edge allows Vayne to stay in lane longer between recalls and gradually win extended wars of attrition. Consider building early grievous wounds if playing Annie.

Best Annie Build Against Vayne

Sorcerer's Shoes is the optimal boots choice against Vayne, providing the mobility and stats Annie needs most in this matchup. The top-performing core items for Annie against Vayne are Stormsurge, Shadowflame and Malignance. This combination gives Annie an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 2 games — well above average and making it the top item path against Vayne. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Annie vs Vayne matchup.

Early Game vs Late Game

Early Game
Annie
50.0%
+0.0% advantage
Annie early game win rateAnnie50.0%
Vayne early game win rateVayne50.0%
Late Game
Annie
50.0%
+0.0% advantage
Annie late game win rateAnnie50.0%
Vayne late game win rateVayne50.0%

The early game (first 15 minutes) is a toss-up between Annie and Vayne, with Annie holding a razor-thin 50.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.

Late game (25+ minutes) is equally balanced, with Annie at 50.0% win rate — only 0.0 points ahead of Vayne. Team fight execution and macro play determine the winner at this stage, not champion matchup advantage.

This matchup is remarkably even at every stage of the game. Neither Annie nor Vayne has a phase-specific advantage, making this a pure skill matchup where individual mechanics, decision-making, and team coordination determine the outcome.

Best Annie Runes Against Vayne

Domination rune tree - Annie primary runes vs VayneDomination
Electrocute - best Annie rune vs VayneCheap Shot - best Annie rune vs VayneGrisly Mementos - best Annie rune vs VayneUltimate Hunter - best Annie rune vs Vayne
Sorcery rune tree - Annie secondary runes vs VayneSorcery
Manaflow Band - best Annie rune vs VayneCelerity - best Annie rune vs Vayne
100.0% WR

The Domination primary with Sorcery secondary combination helps Annie maximize their potential in this closely contested matchup, providing the right mix of offensive and defensive tools to edge out Vayne.


Annie matchup data for League of Legends patch 26.7. The table below shows Annie's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Annie build, runes, laning stats, and early vs late game analysis for that specific matchup.

Annie matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
45.98%876.094612,03938.5%52.1%
42.86%845.986911,27542.5%43.2%
46.00%505.580410,85652.2%40.7%
60.00%505.596211,12952.2%66.7%
55.00%406.093311,39656.5%52.9%
43.59%395.791511,94221.4%56.0%
45.95%375.886912,18741.7%48.0%
55.56%365.384211,00158.8%52.6%
54.29%355.087211,89464.3%47.6%
47.06%345.889510,88735.0%64.3%
37.50%325.796611,72316.7%50.0%
43.33%305.978810,94758.3%33.3%
46.67%305.484012,03137.5%50.0%
44.83%295.871310,38826.7%64.3%
71.43%285.999912,33466.7%76.9%
46.43%285.286310,62838.5%53.3%
48.15%274.282911,46650.0%47.4%
46.15%266.093111,78455.6%41.2%
52.00%256.076910,39233.3%69.2%
33.33%246.387510,52545.5%23.1%
43.48%235.894212,20030.0%53.9%
50.00%225.596811,66666.7%38.5%
30.00%205.582410,34033.3%25.0%
45.00%206.390710,00846.1%42.9%
47.37%195.483011,54312.5%72.7%
33.33%185.21,02611,54730.0%37.5%
70.59%175.875611,05275.0%66.7%
37.50%163.68529,59312.5%62.5%
43.75%166.488710,48150.0%33.3%
37.50%165.782811,50060.0%27.3%
53.33%151.46229,27950.0%55.6%
66.67%156.397811,67170.0%60.0%
61.54%135.372811,40175.0%55.6%
33.33%121.75498,22333.3%33.3%
50.00%121.66919,77057.1%40.0%
41.67%125.194712,03860.0%28.6%
54.55%112.15998,84542.9%75.0%
90.91%114.08319,13785.7%100.0%
45.45%115.51,06912,73325.0%57.1%
70.00%106.588311,780100.0%25.0%
40.00%102.27229,90140.0%40.0%
60.00%105.61,09311,46860.0%60.0%
50.00%106.11,01511,96260.0%40.0%
44.44%96.889112,01120.0%75.0%
33.33%95.29477,19850.0%0.0%
66.67%94.775710,24450.0%80.0%
75.00%81.87039,69180.0%66.7%
62.50%82.977911,22366.7%60.0%
37.50%82.66579,5510.0%50.0%
62.50%81.771711,07660.0%66.7%
85.71%75.694313,370100.0%80.0%
0.00%74.85678,1960.0%0.0%
57.14%75.684711,61166.7%50.0%
71.43%73.56829,60533.3%100.0%
42.86%76.38668,90325.0%66.7%
42.86%75.994313,302100.0%33.3%
85.71%75.195912,52950.0%100.0%
50.00%65.697412,5110.0%60.0%
50.00%64.57117,57525.0%100.0%
66.67%61.251210,7010.0%80.0%
33.33%65.492913,7750.0%40.0%
50.00%65.41,19514,59350.0%50.0%
60.00%54.690112,9020.0%75.0%
60.00%55.01,01012,9840.0%60.0%
20.00%52.35038,22725.0%0.0%

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Annie vs Vayne - Frequently Asked Questions

How does Annie do against Vayne in League of Legends?

Annie wins the Annie vs Vayne matchup with a 50.0% win rate compared to Vayne's 50.0%, a 0.0 percentage point difference. This data is based on 6 recent ranked games in patch 26.7.

How does Annie do against Vayne in the early game?

In the early game, Annie has the advantage against Vayne with a 50.0% win rate versus 50.0%. Annie players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Annie do against Vayne in the late game?

In the late game, Annie takes over the Annie vs Vayne matchup with a 50.0% win rate compared to 50.0%. Annie scales better into team fights and objective contests after 25 minutes.

Who wins the Annie vs Vayne matchup?

Annie wins the matchup against Vayne with a 50.0% win rate in League of Legends patch 26.7. The 0.0 percentage point advantage means Annie is slightly favored in this lane matchup based on 6 games analyzed.

What is the best Annie build against Vayne?

The best Annie build against Vayne includes Stormsurge, Shadowflame, Malignance with Sorcerer's Shoes. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Annie runes against Vayne?

The best Annie runes against Vayne use the Domination primary tree with Sorcery secondary. This rune setup achieves a 100.0% win rate in the Annie vs Vayne matchup. See the full rune breakdown in the matchup comparison above.

Does Annie counter Vayne?

Yes, Annie has a favorable matchup against Vayne with a 50.0% win rate. Annie slightly edges out Vayne in lane based on current patch 26.7 data.

How do I play Annie against Vayne?

When playing Annie against Vayne, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.