
Annievs Vayne
Annie vs Vayne is a very close matchup in LoL patch 26.7. Annie wins with a 50.0% win rate (+0.0%) over Vayne based on 6 games. Annie holds the advantage in both the early and late game. Below you'll find the best Annie build, runes, laning stats, and strategies for the Annie vs Vayne matchup.
Annie Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Annie performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Annie vs Vayne Matchup?

Annie vs Vayne Matchup Summary
The Annie vs Vayne matchup is essentially a coin-flip matchup in League of Legends ranked play. Based on 6 recent matches analyzed, Annie wins with a 50.0% win rate compared to Vayne's 50.0%, giving Annie a 0.0 percentage point advantage. Annie holds a slight edge in both the early and late game, but the margins are thin enough that individual skill and jungle attention will often determine the outcome. Vayne can still find windows through outplays and team coordination. The most significant statistical gap is in crowd control, where Annie leads by 0.8s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Annie has a statistical edge, but the margin is close enough that respecting Vayne's strengths is important. Trade when cooldowns are favorable, track the enemy jungler, and build toward your strongest item spikes to convert the slight advantage into a decisive lead. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Annie vs Vayne Laning Phase Breakdown
Annie is favored during the laning phase against Vayne, winning 3 out of 5 key stat categories. Annie holds advantages in damage, gold income and crowd control, making them the stronger laner in this matchup.
Best Annie Build Against Vayne
Sorcerer's Shoes is the optimal boots choice against Vayne, providing the mobility and stats Annie needs most in this matchup. The top-performing core items for Annie against Vayne are Stormsurge, Shadowflame and Malignance. This combination gives Annie an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 2 games — well above average and making it the top item path against Vayne. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Annie vs Vayne matchup.
Early Game vs Late Game
The early game (first 15 minutes) is a toss-up between Annie and Vayne, with Annie holding a razor-thin 50.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.
Late game (25+ minutes) is equally balanced, with Annie at 50.0% win rate — only 0.0 points ahead of Vayne. Team fight execution and macro play determine the winner at this stage, not champion matchup advantage.
This matchup is remarkably even at every stage of the game. Neither Annie nor Vayne has a phase-specific advantage, making this a pure skill matchup where individual mechanics, decision-making, and team coordination determine the outcome.
Best Annie Runes Against Vayne
The Domination primary with Sorcery secondary combination helps Annie maximize their potential in this closely contested matchup, providing the right mix of offensive and defensive tools to edge out Vayne.
Annie matchup data for League of Legends patch 26.7. The table below shows Annie's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Annie build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 45.98% | 87 | 6.0 | 946 | 12,039 | 38.5% | 52.1% | |
| 42.86% | 84 | 5.9 | 869 | 11,275 | 42.5% | 43.2% | |
| 46.00% | 50 | 5.5 | 804 | 10,856 | 52.2% | 40.7% | |
| 60.00% | 50 | 5.5 | 962 | 11,129 | 52.2% | 66.7% | |
| 55.00% | 40 | 6.0 | 933 | 11,396 | 56.5% | 52.9% | |
| 43.59% | 39 | 5.7 | 915 | 11,942 | 21.4% | 56.0% | |
| 45.95% | 37 | 5.8 | 869 | 12,187 | 41.7% | 48.0% | |
| 55.56% | 36 | 5.3 | 842 | 11,001 | 58.8% | 52.6% | |
| 54.29% | 35 | 5.0 | 872 | 11,894 | 64.3% | 47.6% | |
| 47.06% | 34 | 5.8 | 895 | 10,887 | 35.0% | 64.3% | |
| 37.50% | 32 | 5.7 | 966 | 11,723 | 16.7% | 50.0% | |
| 43.33% | 30 | 5.9 | 788 | 10,947 | 58.3% | 33.3% | |
| 46.67% | 30 | 5.4 | 840 | 12,031 | 37.5% | 50.0% | |
| 44.83% | 29 | 5.8 | 713 | 10,388 | 26.7% | 64.3% | |
| 71.43% | 28 | 5.9 | 999 | 12,334 | 66.7% | 76.9% | |
| 46.43% | 28 | 5.2 | 863 | 10,628 | 38.5% | 53.3% | |
| 48.15% | 27 | 4.2 | 829 | 11,466 | 50.0% | 47.4% | |
| 46.15% | 26 | 6.0 | 931 | 11,784 | 55.6% | 41.2% | |
| 52.00% | 25 | 6.0 | 769 | 10,392 | 33.3% | 69.2% | |
| 33.33% | 24 | 6.3 | 875 | 10,525 | 45.5% | 23.1% | |
| 43.48% | 23 | 5.8 | 942 | 12,200 | 30.0% | 53.9% | |
| 50.00% | 22 | 5.5 | 968 | 11,666 | 66.7% | 38.5% | |
| 30.00% | 20 | 5.5 | 824 | 10,340 | 33.3% | 25.0% | |
| 45.00% | 20 | 6.3 | 907 | 10,008 | 46.1% | 42.9% | |
| 47.37% | 19 | 5.4 | 830 | 11,543 | 12.5% | 72.7% | |
| 33.33% | 18 | 5.2 | 1,026 | 11,547 | 30.0% | 37.5% | |
| 70.59% | 17 | 5.8 | 756 | 11,052 | 75.0% | 66.7% | |
| 37.50% | 16 | 3.6 | 852 | 9,593 | 12.5% | 62.5% | |
| 43.75% | 16 | 6.4 | 887 | 10,481 | 50.0% | 33.3% | |
| 37.50% | 16 | 5.7 | 828 | 11,500 | 60.0% | 27.3% | |
| 53.33% | 15 | 1.4 | 622 | 9,279 | 50.0% | 55.6% | |
| 66.67% | 15 | 6.3 | 978 | 11,671 | 70.0% | 60.0% | |
| 61.54% | 13 | 5.3 | 728 | 11,401 | 75.0% | 55.6% | |
| 33.33% | 12 | 1.7 | 549 | 8,223 | 33.3% | 33.3% | |
| 50.00% | 12 | 1.6 | 691 | 9,770 | 57.1% | 40.0% | |
| 41.67% | 12 | 5.1 | 947 | 12,038 | 60.0% | 28.6% | |
| 54.55% | 11 | 2.1 | 599 | 8,845 | 42.9% | 75.0% | |
| 90.91% | 11 | 4.0 | 831 | 9,137 | 85.7% | 100.0% | |
| 45.45% | 11 | 5.5 | 1,069 | 12,733 | 25.0% | 57.1% | |
| 70.00% | 10 | 6.5 | 883 | 11,780 | 100.0% | 25.0% | |
| 40.00% | 10 | 2.2 | 722 | 9,901 | 40.0% | 40.0% | |
| 60.00% | 10 | 5.6 | 1,093 | 11,468 | 60.0% | 60.0% | |
| 50.00% | 10 | 6.1 | 1,015 | 11,962 | 60.0% | 40.0% | |
| 44.44% | 9 | 6.8 | 891 | 12,011 | 20.0% | 75.0% | |
| 33.33% | 9 | 5.2 | 947 | 7,198 | 50.0% | 0.0% | |
| 66.67% | 9 | 4.7 | 757 | 10,244 | 50.0% | 80.0% | |
| 75.00% | 8 | 1.8 | 703 | 9,691 | 80.0% | 66.7% | |
| 62.50% | 8 | 2.9 | 779 | 11,223 | 66.7% | 60.0% | |
| 37.50% | 8 | 2.6 | 657 | 9,551 | 0.0% | 50.0% | |
| 62.50% | 8 | 1.7 | 717 | 11,076 | 60.0% | 66.7% | |
| 85.71% | 7 | 5.6 | 943 | 13,370 | 100.0% | 80.0% | |
| 0.00% | 7 | 4.8 | 567 | 8,196 | 0.0% | 0.0% | |
| 57.14% | 7 | 5.6 | 847 | 11,611 | 66.7% | 50.0% | |
| 71.43% | 7 | 3.5 | 682 | 9,605 | 33.3% | 100.0% | |
| 42.86% | 7 | 6.3 | 866 | 8,903 | 25.0% | 66.7% | |
| 42.86% | 7 | 5.9 | 943 | 13,302 | 100.0% | 33.3% | |
| 85.71% | 7 | 5.1 | 959 | 12,529 | 50.0% | 100.0% | |
| 50.00% | 6 | 5.6 | 974 | 12,511 | 0.0% | 60.0% | |
| 50.00% | 6 | 4.5 | 711 | 7,575 | 25.0% | 100.0% | |
| 66.67% | 6 | 1.2 | 512 | 10,701 | 0.0% | 80.0% | |
| 33.33% | 6 | 5.4 | 929 | 13,775 | 0.0% | 40.0% | |
| 50.00% | 6 | 5.4 | 1,195 | 14,593 | 50.0% | 50.0% | |
| 60.00% | 5 | 4.6 | 901 | 12,902 | 0.0% | 75.0% | |
| 60.00% | 5 | 5.0 | 1,010 | 12,984 | 0.0% | 60.0% | |
| 20.00% | 5 | 2.3 | 503 | 8,227 | 25.0% | 0.0% | |
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Annie vs Vayne - Frequently Asked Questions
How does Annie do against Vayne in League of Legends?
Annie wins the Annie vs Vayne matchup with a 50.0% win rate compared to Vayne's 50.0%, a 0.0 percentage point difference. This data is based on 6 recent ranked games in patch 26.7.
How does Annie do against Vayne in the early game?
In the early game, Annie has the advantage against Vayne with a 50.0% win rate versus 50.0%. Annie players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Annie do against Vayne in the late game?
In the late game, Annie takes over the Annie vs Vayne matchup with a 50.0% win rate compared to 50.0%. Annie scales better into team fights and objective contests after 25 minutes.
Who wins the Annie vs Vayne matchup?
Annie wins the matchup against Vayne with a 50.0% win rate in League of Legends patch 26.7. The 0.0 percentage point advantage means Annie is slightly favored in this lane matchup based on 6 games analyzed.
What is the best Annie build against Vayne?
The best Annie build against Vayne includes Stormsurge, Shadowflame, Malignance with Sorcerer's Shoes. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.
What are the best Annie runes against Vayne?
The best Annie runes against Vayne use the Domination primary tree with Sorcery secondary. This rune setup achieves a 100.0% win rate in the Annie vs Vayne matchup. See the full rune breakdown in the matchup comparison above.
Does Annie counter Vayne?
Yes, Annie has a favorable matchup against Vayne with a 50.0% win rate. Annie slightly edges out Vayne in lane based on current patch 26.7 data.
How do I play Annie against Vayne?
When playing Annie against Vayne, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.
