
Annievs Seraphine
Annie vs Seraphine is a decisive matchup in LoL patch 26.7. Annie wins with a 54.5% win rate (+9.1%) over Seraphine based on 11 games. Seraphine wins the early laning phase while Annie scales better into the late game. Below you'll find the best Annie build, runes, laning stats, and strategies for the Annie vs Seraphine matchup.
Annie Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Annie performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Annie vs Seraphine Matchup?

Annie vs Seraphine Matchup Summary
The Annie vs Seraphine matchup is a decisive matchup in League of Legends ranked play. Based on 11 recent matches analyzed, Annie wins with a 54.5% win rate compared to Seraphine's 45.5%, giving Annie a 9.1 percentage point advantage. Game phase dynamics play a critical role here: Seraphine controls the early laning stage, but Annie outscales as the game goes longer. The matchup shifts dramatically depending on game length — Seraphine needs to press advantages before Annie reaches their power spikes, while Annie should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in damage output, where Annie leads by 265 DMG/min — a difference that heavily influences the outcome of trades and skirmishes. Annie players can confidently pick into Seraphine and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Seraphine away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Annie vs Seraphine Laning Phase Breakdown
Annie is favored during the laning phase against Seraphine, winning 4 out of 5 key stat categories. Annie holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.
Best Annie Build Against Seraphine
Sorcerer's Shoes is the optimal boots choice against Seraphine, providing the mobility and stats Annie needs most in this matchup. The top-performing core items for Annie against Seraphine are Liandry's Torment, Malignance and Rabadon's Deathcap. This combination gives Annie an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Annie vs Seraphine matchup.
Early Game vs Late Game
Seraphine dominates the early game (first 15 minutes) with a commanding 57.1% win rate — a 14.3 percentage point lead over Annie. This lopsided early game means Seraphine can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Annie is far superior in the late game (25+ minutes), boasting a 75.0% win rate — 50.0 points above Seraphine. Extended games heavily favor Annie, whose kit and scaling make them a dominant force in team fights and objective control.
This matchup features a dramatic power shift: Seraphine must aggressively press their early advantage and close out the game before Annie reaches their scaling breakpoints. If Annie survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.
Best Annie Runes Against Seraphine
Running Domination primary with Sorcery secondary allows Annie to press their advantage against Seraphine, amplifying the strengths that make this a favorable matchup.
Annie matchup data for League of Legends patch 26.7. The table below shows Annie's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Annie build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 45.98% | 87 | 6.0 | 946 | 12,039 | 38.5% | 52.1% | |
| 42.86% | 84 | 5.9 | 869 | 11,275 | 42.5% | 43.2% | |
| 46.00% | 50 | 5.5 | 804 | 10,856 | 52.2% | 40.7% | |
| 60.00% | 50 | 5.5 | 962 | 11,129 | 52.2% | 66.7% | |
| 55.00% | 40 | 6.0 | 933 | 11,396 | 56.5% | 52.9% | |
| 43.59% | 39 | 5.7 | 915 | 11,942 | 21.4% | 56.0% | |
| 45.95% | 37 | 5.8 | 869 | 12,187 | 41.7% | 48.0% | |
| 55.56% | 36 | 5.3 | 842 | 11,001 | 58.8% | 52.6% | |
| 54.29% | 35 | 5.0 | 872 | 11,894 | 64.3% | 47.6% | |
| 47.06% | 34 | 5.8 | 895 | 10,887 | 35.0% | 64.3% | |
| 37.50% | 32 | 5.7 | 966 | 11,723 | 16.7% | 50.0% | |
| 43.33% | 30 | 5.9 | 788 | 10,947 | 58.3% | 33.3% | |
| 46.67% | 30 | 5.4 | 840 | 12,031 | 37.5% | 50.0% | |
| 44.83% | 29 | 5.8 | 713 | 10,388 | 26.7% | 64.3% | |
| 71.43% | 28 | 5.9 | 999 | 12,334 | 66.7% | 76.9% | |
| 46.43% | 28 | 5.2 | 863 | 10,628 | 38.5% | 53.3% | |
| 48.15% | 27 | 4.2 | 829 | 11,466 | 50.0% | 47.4% | |
| 46.15% | 26 | 6.0 | 931 | 11,784 | 55.6% | 41.2% | |
| 52.00% | 25 | 6.0 | 769 | 10,392 | 33.3% | 69.2% | |
| 33.33% | 24 | 6.3 | 875 | 10,525 | 45.5% | 23.1% | |
| 43.48% | 23 | 5.8 | 942 | 12,200 | 30.0% | 53.9% | |
| 50.00% | 22 | 5.5 | 968 | 11,666 | 66.7% | 38.5% | |
| 30.00% | 20 | 5.5 | 824 | 10,340 | 33.3% | 25.0% | |
| 45.00% | 20 | 6.3 | 907 | 10,008 | 46.1% | 42.9% | |
| 47.37% | 19 | 5.4 | 830 | 11,543 | 12.5% | 72.7% | |
| 33.33% | 18 | 5.2 | 1,026 | 11,547 | 30.0% | 37.5% | |
| 70.59% | 17 | 5.8 | 756 | 11,052 | 75.0% | 66.7% | |
| 37.50% | 16 | 3.6 | 852 | 9,593 | 12.5% | 62.5% | |
| 43.75% | 16 | 6.4 | 887 | 10,481 | 50.0% | 33.3% | |
| 37.50% | 16 | 5.7 | 828 | 11,500 | 60.0% | 27.3% | |
| 53.33% | 15 | 1.4 | 622 | 9,279 | 50.0% | 55.6% | |
| 66.67% | 15 | 6.3 | 978 | 11,671 | 70.0% | 60.0% | |
| 61.54% | 13 | 5.3 | 728 | 11,401 | 75.0% | 55.6% | |
| 33.33% | 12 | 1.7 | 549 | 8,223 | 33.3% | 33.3% | |
| 50.00% | 12 | 1.6 | 691 | 9,770 | 57.1% | 40.0% | |
| 41.67% | 12 | 5.1 | 947 | 12,038 | 60.0% | 28.6% | |
| 54.55% | 11 | 2.1 | 599 | 8,845 | 42.9% | 75.0% | |
| 90.91% | 11 | 4.0 | 831 | 9,137 | 85.7% | 100.0% | |
| 45.45% | 11 | 5.5 | 1,069 | 12,733 | 25.0% | 57.1% | |
| 70.00% | 10 | 6.5 | 883 | 11,780 | 100.0% | 25.0% | |
| 40.00% | 10 | 2.2 | 722 | 9,901 | 40.0% | 40.0% | |
| 60.00% | 10 | 5.6 | 1,093 | 11,468 | 60.0% | 60.0% | |
| 50.00% | 10 | 6.1 | 1,015 | 11,962 | 60.0% | 40.0% | |
| 44.44% | 9 | 6.8 | 891 | 12,011 | 20.0% | 75.0% | |
| 33.33% | 9 | 5.2 | 947 | 7,198 | 50.0% | 0.0% | |
| 66.67% | 9 | 4.7 | 757 | 10,244 | 50.0% | 80.0% | |
| 75.00% | 8 | 1.8 | 703 | 9,691 | 80.0% | 66.7% | |
| 62.50% | 8 | 2.9 | 779 | 11,223 | 66.7% | 60.0% | |
| 37.50% | 8 | 2.6 | 657 | 9,551 | 0.0% | 50.0% | |
| 62.50% | 8 | 1.7 | 717 | 11,076 | 60.0% | 66.7% | |
| 85.71% | 7 | 5.6 | 943 | 13,370 | 100.0% | 80.0% | |
| 0.00% | 7 | 4.8 | 567 | 8,196 | 0.0% | 0.0% | |
| 57.14% | 7 | 5.6 | 847 | 11,611 | 66.7% | 50.0% | |
| 71.43% | 7 | 3.5 | 682 | 9,605 | 33.3% | 100.0% | |
| 42.86% | 7 | 6.3 | 866 | 8,903 | 25.0% | 66.7% | |
| 42.86% | 7 | 5.9 | 943 | 13,302 | 100.0% | 33.3% | |
| 85.71% | 7 | 5.1 | 959 | 12,529 | 50.0% | 100.0% | |
| 50.00% | 6 | 5.6 | 974 | 12,511 | 0.0% | 60.0% | |
| 50.00% | 6 | 4.5 | 711 | 7,575 | 25.0% | 100.0% | |
| 66.67% | 6 | 1.2 | 512 | 10,701 | 0.0% | 80.0% | |
| 33.33% | 6 | 5.4 | 929 | 13,775 | 0.0% | 40.0% | |
| 50.00% | 6 | 5.4 | 1,195 | 14,593 | 50.0% | 50.0% | |
| 60.00% | 5 | 4.6 | 901 | 12,902 | 0.0% | 75.0% | |
| 60.00% | 5 | 5.0 | 1,010 | 12,984 | 0.0% | 60.0% | |
| 20.00% | 5 | 2.3 | 503 | 8,227 | 25.0% | 0.0% | |
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Annie vs Seraphine - Frequently Asked Questions
How does Annie do against Seraphine in League of Legends?
Annie wins the Annie vs Seraphine matchup with a 54.5% win rate compared to Seraphine's 45.5%, a 9.1 percentage point difference. This data is based on 11 recent ranked games in patch 26.7.
How does Annie do against Seraphine in the early game?
In the early game, Seraphine has the advantage against Annie with a 57.1% win rate versus 42.9%. Seraphine players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Annie do against Seraphine in the late game?
In the late game, Annie takes over the Annie vs Seraphine matchup with a 75.0% win rate compared to 25.0%. Annie scales better into team fights and objective contests after 25 minutes.
Who wins the Annie vs Seraphine matchup?
Annie wins the matchup against Seraphine with a 54.5% win rate in League of Legends patch 26.7. The 9.1 percentage point advantage means Annie is significantly favored in this lane matchup based on 11 games analyzed.
What is the best Annie build against Seraphine?
The best Annie build against Seraphine includes Liandry's Torment, Malignance, Rabadon's Deathcap with Sorcerer's Shoes. Check the matchup breakdown above for the full item path and build order.
What are the best Annie runes against Seraphine?
The best Annie runes against Seraphine use the Domination primary tree with Sorcery secondary. This rune setup achieves a 100.0% win rate in the Annie vs Seraphine matchup. See the full rune breakdown in the matchup comparison above.
Does Annie counter Seraphine?
Yes, Annie has a favorable matchup against Seraphine with a 54.5% win rate. Annie strongly counters Seraphine in lane based on current patch 26.7 data.
How do I play Annie against Seraphine?
When playing Annie against Seraphine, leverage your statistical advantages by trading aggressively during favorable windows. Play safe early and scale into your power spikes where you outperform Seraphine. Build the recommended items and runes for this specific matchup for the best results.
