Annievs Seraphine
Annie vs Seraphine is a decisive matchup in LoL patch 26.11. Seraphine wins with a 63.6% win rate (+27.3%) over Annie based on 22 games. Seraphine holds the advantage in both the early and late game. Below you'll find the best Annie build, runes, laning stats, and strategies for the Annie vs Seraphine matchup.
Annie Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Annie performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Annie vs Seraphine Matchup?
Annie vs Seraphine Matchup Summary
The Annie vs Seraphine matchup is a decisive matchup in League of Legends ranked play. Based on 22 recent matches analyzed, Seraphine wins with a 63.6% win rate compared to Annie's 36.4%, giving Seraphine a 27.3 percentage point advantage. Seraphine dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Annie players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in damage output, where Annie leads by 262 DMG/min — a difference that heavily influences the outcome of trades and skirmishes. Seraphine has a strong advantage in this matchup. Annie players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Seraphine overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Annie vs Seraphine Laning Phase Breakdown
Annie is favored during the laning phase against Seraphine, winning 3 out of 5 key stat categories. Annie holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.
Best Annie Build Against Seraphine
Boots of Swiftness is the optimal boots choice against Seraphine, providing the mobility and stats Annie needs most in this matchup. The top-performing core items for Annie against Seraphine are Stormsurge, Shadowflame and Malignance. This combination gives Annie an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 66.7% win rate across 3 games — well above average and making it the top item path against Seraphine. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Annie vs Seraphine matchup.
Early Game vs Late Game
Annie40.0%
Seraphine60.0%Annie35.3%Seraphine64.7%Seraphine dominates the early game (first 15 minutes) with a commanding 60.0% win rate — a 20.0 percentage point lead over Annie. This lopsided early game means Seraphine can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Seraphine is far superior in the late game (25+ minutes), boasting a 64.7% win rate — 29.4 points above Annie. Extended games heavily favor Seraphine, whose kit and scaling make them a dominant force in team fights and objective control.
Seraphine holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Annie players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.
Best Annie Runes Against Seraphine
Domination
Sorcery
The Domination and Sorcery rune setup gives Annie the best tools to compete against Seraphine in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.
Annie matchup data for League of Legends patch 26.11. The table below shows Annie's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Annie build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 46.63% | 163 | 6.0 | 901 | 10,997 | 42.9% | 49.5% | |
| 50.41% | 123 | 5.8 | 911 | 11,277 | 46.8% | 54.1% | |
| 43.56% | 101 | 5.2 | 805 | 11,610 | 38.5% | 46.8% | |
| 47.37% | 95 | 6.0 | 980 | 11,155 | 46.1% | 48.8% | |
| 39.78% | 93 | 5.8 | 869 | 11,179 | 28.6% | 49.0% | |
| 50.00% | 74 | 5.7 | 915 | 11,178 | 50.0% | 50.0% | |
| 49.32% | 73 | 5.3 | 870 | 11,079 | 43.8% | 53.7% | |
| 38.03% | 71 | 5.6 | 865 | 10,269 | 41.2% | 35.1% | |
| 47.14% | 70 | 5.2 | 890 | 11,685 | 41.7% | 50.0% | |
| 42.03% | 69 | 5.8 | 810 | 11,311 | 30.8% | 48.8% | |
| 52.31% | 65 | 5.4 | 915 | 11,174 | 50.0% | 53.9% | |
| 59.32% | 59 | 5.3 | 917 | 11,910 | 52.4% | 63.2% | |
| 51.79% | 56 | 5.2 | 982 | 11,641 | 40.0% | 61.3% | |
| 43.40% | 53 | 6.1 | 952 | 11,675 | 38.1% | 46.9% | |
| 40.38% | 52 | 5.5 | 732 | 9,641 | 36.4% | 47.4% | |
| 35.29% | 51 | 5.8 | 851 | 11,571 | 27.8% | 39.4% | |
| 50.00% | 50 | 5.5 | 818 | 10,808 | 48.0% | 52.0% | |
| 43.75% | 48 | 5.6 | 872 | 10,958 | 39.1% | 48.0% | |
| 40.43% | 47 | 5.8 | 901 | 9,137 | 43.8% | 33.3% | |
| 48.94% | 47 | 5.4 | 971 | 12,637 | 38.9% | 55.2% | |
| 44.19% | 43 | 5.8 | 890 | 11,311 | 40.0% | 47.8% | |
| 48.84% | 43 | 6.1 | 773 | 10,575 | 63.6% | 33.3% | |
| 58.14% | 43 | 5.9 | 860 | 11,451 | 61.9% | 54.5% | |
| 57.50% | 40 | 6.4 | 909 | 11,943 | 46.7% | 64.0% | |
| 53.85% | 39 | 5.9 | 948 | 11,079 | 58.8% | 50.0% | |
| 46.15% | 39 | 5.0 | 932 | 11,808 | 50.0% | 43.5% | |
| 55.26% | 38 | 5.7 | 989 | 13,306 | 62.5% | 53.3% | |
| 56.76% | 37 | 5.9 | 903 | 10,954 | 52.6% | 61.1% | |
| 61.11% | 36 | 5.1 | 864 | 12,164 | 66.7% | 59.3% | |
| 41.67% | 36 | 5.4 | 913 | 10,730 | 25.0% | 55.0% | |
| 51.61% | 31 | 5.8 | 842 | 10,313 | 47.4% | 58.3% | |
| 30.00% | 30 | 5.8 | 773 | 9,858 | 37.5% | 21.4% | |
| 41.38% | 29 | 5.5 | 984 | 10,340 | 37.5% | 46.1% | |
| 42.86% | 28 | 4.8 | 862 | 11,811 | 33.3% | 47.4% | |
| 46.43% | 28 | 5.9 | 913 | 11,753 | 50.0% | 44.4% | |
| 42.31% | 26 | 4.1 | 839 | 11,257 | 41.7% | 42.9% | |
| 53.85% | 26 | 5.8 | 920 | 9,345 | 57.1% | 50.0% | |
| 44.00% | 25 | 3.1 | 742 | 9,606 | 40.0% | 46.7% | |
| 36.00% | 25 | 4.9 | 789 | 10,942 | 41.7% | 30.8% | |
| 63.64% | 22 | 5.7 | 791 | 10,676 | 69.2% | 55.6% | |
| 68.18% | 22 | 5.7 | 1,081 | 12,128 | 50.0% | 78.6% | |
| 45.45% | 22 | 5.5 | 877 | 10,945 | 40.0% | 50.0% | |
| 40.91% | 22 | 5.9 | 882 | 9,325 | 20.0% | 58.3% | |
| 36.36% | 22 | 2.3 | 770 | 11,963 | 40.0% | 35.3% | |
| 65.00% | 20 | 5.9 | 872 | 10,945 | 55.6% | 72.7% | |
| 47.37% | 19 | 5.6 | 854 | 11,064 | 25.0% | 63.6% | |
| 42.11% | 19 | 1.6 | 747 | 9,548 | 50.0% | 38.5% | |
| 56.25% | 16 | 2.3 | 695 | 11,375 | 66.7% | 50.0% | |
| 46.67% | 15 | 4.6 | 913 | 10,735 | 50.0% | 44.4% | |
| 60.00% | 15 | 6.2 | 1,028 | 12,499 | 60.0% | 60.0% | |
| 28.57% | 14 | 6.3 | 977 | 9,473 | 0.0% | 66.7% | |
| 61.54% | 13 | 1.5 | 628 | 10,471 | 66.7% | 57.1% | |
| 38.46% | 13 | 6.1 | 1,027 | 11,945 | 50.0% | 33.3% | |
| 38.46% | 13 | 5.1 | 1,089 | 11,285 | 50.0% | 28.6% | |
| 61.54% | 13 | 1.2 | 696 | 9,806 | 75.0% | 55.6% | |
| 63.64% | 11 | 3.5 | 696 | 9,585 | 50.0% | 80.0% | |
| 54.55% | 11 | 6.0 | 877 | 10,894 | 57.1% | 50.0% | |
| 63.64% | 11 | 1.8 | 825 | 10,705 | 50.0% | 71.4% | |
| 54.55% | 11 | 2.1 | 712 | 9,974 | 80.0% | 33.3% | |
| 60.00% | 10 | 6.7 | 822 | 11,009 | 66.7% | 50.0% | |
| 40.00% | 10 | 1.6 | 638 | 11,039 | 0.0% | 57.1% | |
| 60.00% | 10 | 6.5 | 984 | 13,174 | 100.0% | 50.0% | |
| 50.00% | 10 | 5.7 | 726 | 10,234 | 50.0% | 50.0% | |
| 40.00% | 10 | 4.8 | 948 | 12,319 | 33.3% | 42.9% | |
| 60.00% | 10 | 4.9 | 1,036 | 13,494 | 0.0% | 75.0% | |
| 66.67% | 9 | 5.7 | 945 | 13,134 | 66.7% | 66.7% | |
| 66.67% | 9 | 5.6 | 866 | 10,998 | 100.0% | 50.0% | |
| 33.33% | 9 | 5.5 | 782 | 11,780 | 0.0% | 50.0% | |
| 66.67% | 9 | 1.8 | 590 | 9,988 | 33.3% | 83.3% | |
| 66.67% | 9 | 1.8 | 620 | 9,682 | 100.0% | 57.1% | |
| 66.67% | 9 | 6.0 | 914 | 10,556 | 66.7% | 66.7% | |
| 25.00% | 8 | 1.5 | 754 | 9,416 | 0.0% | 33.3% | |
| 50.00% | 8 | 1.6 | 510 | 9,819 | 66.7% | 40.0% | |
| 50.00% | 8 | 5.3 | 846 | 11,041 | 50.0% | 50.0% | |
| 28.57% | 7 | 5.8 | 1,049 | 13,572 | 100.0% | 16.7% | |
| 57.14% | 7 | 6.2 | 803 | 10,918 | 50.0% | 66.7% | |
| 71.43% | 7 | 1.2 | 687 | 8,934 | 83.3% | 0.0% | |
| 71.43% | 7 | 5.3 | 1,050 | 13,583 | 100.0% | 60.0% | |
| 16.67% | 6 | 5.2 | 1,067 | 14,702 | 0.0% | 16.7% | |
| 66.67% | 6 | 1.3 | 526 | 9,719 | 0.0% | 66.7% | |
| 66.67% | 6 | 7.0 | 1,004 | 12,479 | 66.7% | 66.7% | |
| 16.67% | 6 | 4.5 | 767 | 10,994 | 50.0% | 0.0% | |
| 66.67% | 6 | 5.7 | 1,070 | 12,756 | 50.0% | 75.0% | |
| 0.00% | 6 | 4.1 | 824 | 8,489 | 0.0% | 0.0% | |
| 60.00% | 5 | 6.3 | 973 | 10,682 | 50.0% | 100.0% | |
| 40.00% | 5 | 1.5 | 639 | 9,293 | 25.0% | 100.0% | |
| 40.00% | 5 | 4.5 | 834 | 10,634 | 33.3% | 50.0% | |
| 40.00% | 5 | 1.9 | 608 | 9,730 | 50.0% | 33.3% | |
| 80.00% | 5 | 7.0 | 1,062 | 10,096 | 75.0% | 100.0% | |
| 20.00% | 5 | 5.8 | 798 | 9,640 | 0.0% | 50.0% | |
| 80.00% | 5 | 4.9 | 893 | 12,745 | 66.7% | 100.0% | |
| 40.00% | 5 | 1.6 | 585 | 8,471 | 33.3% | 50.0% | |
| 60.00% | 5 | 5.2 | 916 | 12,262 | 0.0% | 75.0% | |
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Annie vs Seraphine - Frequently Asked Questions
How does Annie do against Seraphine in League of Legends?
Seraphine wins the Annie vs Seraphine matchup with a 63.6% win rate compared to Annie's 36.4%, a 27.3 percentage point difference. This data is based on 22 recent ranked games in patch 26.11.
How does Annie do against Seraphine in the early game?
In the early game, Seraphine has the advantage against Annie with a 60.0% win rate versus 40.0%. Seraphine players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Annie do against Seraphine in the late game?
In the late game, Seraphine takes over the Annie vs Seraphine matchup with a 64.7% win rate compared to 35.3%. Seraphine scales better into team fights and objective contests after 25 minutes.
Who wins the Annie vs Seraphine matchup?
Seraphine wins the matchup against Annie with a 63.6% win rate in League of Legends patch 26.11. The 27.3 percentage point advantage means Seraphine is significantly favored in this lane matchup based on 22 games analyzed.
What is the best Annie build against Seraphine?
The best Annie build against Seraphine includes Stormsurge, Shadowflame, Malignance with Boots of Swiftness. This build achieves a 66.7% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.
What are the best Annie runes against Seraphine?
The best Annie runes against Seraphine use the Domination primary tree with Sorcery secondary. This rune setup achieves a 100.0% win rate in the Annie vs Seraphine matchup. See the full rune breakdown in the matchup comparison above.
Does Annie counter Seraphine?
No, Annie struggles against Seraphine with only a 36.4% win rate. Seraphine has the advantage in this matchup. Annie players should focus on safe farming and avoiding extended trades to minimize Seraphine's lead.
How do I play Annie against Seraphine?
When playing Annie against Seraphine, play cautiously and avoid Seraphine's power spikes. Look for jungle assistance and team-dependent plays since Seraphine has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.