Annie - League of Legends Champion
Win Rate
49.5%
Pick Rate
1.5%

Annievs Nautilus

DMageSupport
Patch26.12
Matches328,930
LaneAll Lanes
TierAll Tiers
Last UpdatedJun 24, 2026
MethodologyData Methodology

Annie vs Nautilus is a decisive matchup in LoL patch 26.12. Nautilus wins with a 66.7% win rate (+33.3%) over Annie based on 6 games. Annie wins the early laning phase while Nautilus scales better into the late game. Below you'll find the best Annie build, runes, laning stats, and strategies for the Annie vs Nautilus matchup.

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Annie Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Annie performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Annie - 33.3% win rate in this matchup
Annie
33.3% WR
VS
Nautilus vs Annie matchup - 66.7% win rate
Nautilus
66.7% WR

Who Wins the Annie vs Nautilus Matchup?

Nautilus wins the Annie vs Nautilus matchup
Winner
Nautilus
Matches: 6
33.3%
Win Rate
66.7%
2.0
CS / min
1.6
609
DMG / min
384
9,112
Gold / game
9,170
51
Heal / min
106
338
DMG Mitigated / min
1,212
1.0
CC / min
2.0
50.0%
Early Game WR
50.0%
0.0%
Late Game WR
100.0%

Annie vs Nautilus Matchup Summary

The Annie vs Nautilus matchup is a decisive matchup in League of Legends ranked play. Based on 6 recent matches analyzed, Nautilus wins with a 66.7% win rate compared to Annie's 33.3%, giving Nautilus a 33.3 percentage point advantage. Game phase dynamics play a critical role here: Annie controls the early laning stage, but Nautilus outscales as the game goes longer. The matchup shifts dramatically depending on game length — Annie needs to press advantages before Nautilus reaches their power spikes, while Nautilus should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in sustain, where Nautilus leads by 930 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Nautilus has a strong advantage in this matchup. Annie players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Nautilus overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Annie vs Nautilus Laning Phase Breakdown

Nautilus wins the laning phase against Annie in League of Legends

Nautilus is favored during the laning phase against Annie, winning 3 out of 5 key stat categories. Nautilus holds advantages in gold income, crowd control and sustain, making them the stronger laner in this matchup.

Farming
2.0Annie
1.6Nautilus
Annie edges out Nautilus by 0.3 CS per minute — a moderate farming advantage that adds up to roughly 5 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Annie.
Damage
609Annie
384Nautilus
Annie heavily out-damages Nautilus by 225 DMG/min, dominating both short trades and all-in fights. Nautilus should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Annie's sustained damage advantage take over.
Economy
9,112Annie
9,170Nautilus
Annie and Nautilus generate nearly equal gold per game, with just a 58 gold difference. Neither champion has a clear economic advantage, so gold leads will depend on individual play quality, kill participation, and objective contributions.
Utility
1.0Annie
2.0Nautilus
Nautilus brings significantly more crowd control than Annie, with 1.0 more seconds of CC per minute. This large utility gap makes Nautilus far more valuable in setting up jungle ganks, controlling objectives, and locking down targets in team fights. Annie should invest in tenacity and position carefully to avoid being chain-CC'd.
Sustain
389Annie
1,319Nautilus
Nautilus vastly out-sustains Annie, healing and mitigating 930 more damage per minute. This massive durability gap means Nautilus can absorb significant punishment and remain in lane while Annie is forced to recall. Building grievous wounds early is essential for Annie, and focusing on burst trade patterns rather than sustained fights is critical.

Best Annie Build Against Nautilus

Ionian Boots of Lucidity is the optimal boots choice against Nautilus, providing the mobility and stats Annie needs most in this matchup. The top-performing core items for Annie against Nautilus are Liandry's Torment, Malignance and Rabadon's Deathcap. This combination gives Annie an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Annie vs Nautilus matchup.

Early Game vs Late Game

Early Game
Annie
50.0%
+0.0% advantage
Annie early game win rateAnnie50.0%
Nautilus early game win rateNautilus50.0%
Late Game
Nautilus
100.0%
+100.0% advantage
Annie late game win rateAnnie0.0%
Nautilus late game win rateNautilus100.0%

The early game (first 15 minutes) is a toss-up between Annie and Nautilus, with Annie holding a razor-thin 50.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.

Nautilus is far superior in the late game (25+ minutes), boasting a 100.0% win rate — 100.0 points above Annie. Extended games heavily favor Nautilus, whose kit and scaling make them a dominant force in team fights and objective control.

The power dynamics shift as the game progresses — Annie has the edge early, but Nautilus gradually takes over. However, the margins are slim enough that either champion can win at any stage with the right plays. Focus on taking advantages when you have them rather than waiting for a specific game phase.

Best Annie Runes Against Nautilus

Domination rune tree - Annie primary runes vs NautilusDomination
Electrocute - best Annie rune vs NautilusCheap Shot - best Annie rune vs NautilusGrisly Mementos - best Annie rune vs NautilusRelentless Hunter - best Annie rune vs Nautilus
Sorcery rune tree - Annie secondary runes vs NautilusSorcery
Absolute Focus - best Annie rune vs NautilusManaflow Band - best Annie rune vs Nautilus
100.0% WR

The Domination and Sorcery rune setup gives Annie the best tools to compete against Nautilus in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Annie matchup data for League of Legends patch 26.12. The table below shows Annie's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Annie build, runes, laning stats, and early vs late game analysis for that specific matchup.

Annie matchup win rates and stats in League of Legends patch 26.12
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
42.31%786.089411,47440.5%43.9%
54.55%555.892610,40650.0%59.3%
40.43%475.082711,23331.3%45.2%
53.66%415.994811,13463.2%45.5%
36.59%415.984811,52238.9%34.8%
50.00%405.499211,85558.3%46.4%
54.05%375.781111,55062.5%47.6%
50.00%365.179711,72850.0%50.0%
36.36%336.387711,35730.8%40.0%
48.39%315.790011,36422.2%59.1%
51.72%295.575810,55956.3%46.1%
60.71%285.889812,23060.0%61.1%
57.14%285.493611,64646.1%66.7%
40.74%275.494011,33233.3%46.7%
74.07%275.188112,76542.9%85.0%
37.50%246.293011,17630.8%45.5%
33.33%245.883611,55927.3%38.5%
58.33%245.296111,16633.3%73.3%
39.13%235.885310,12735.7%44.4%
40.91%225.486612,78342.9%40.0%
52.38%216.282110,91828.6%64.3%
66.67%216.090011,84763.6%70.0%
50.00%181.97029,70040.0%62.5%
66.67%185.499011,41071.4%63.6%
44.44%186.31,01011,42433.3%50.0%
52.94%175.71,19611,46650.0%55.6%
52.94%172.95988,51566.7%45.5%
25.00%123.270910,42250.0%12.5%
66.67%125.877011,55375.0%62.5%
41.67%125.81,14012,87725.0%50.0%
33.33%125.896812,23025.0%37.5%
33.33%126.27799,52725.0%50.0%
75.00%125.475711,08066.7%83.3%
40.00%101.86909,37450.0%25.0%
50.00%105.91,03611,24650.0%50.0%
30.00%106.31,02913,21450.0%16.7%
75.00%85.61,03313,14566.7%80.0%
25.00%85.284710,2060.0%40.0%
75.00%86.31,01911,95175.0%75.0%
50.00%86.17889,60340.0%66.7%
25.00%85.194711,21233.3%20.0%
50.00%85.281610,61033.3%60.0%
25.00%85.263110,07025.0%25.0%
28.57%73.083411,3300.0%50.0%
57.14%75.196910,39150.0%66.7%
16.67%61.47058,56733.3%0.0%
50.00%61.36206,08850.0%50.0%
33.33%62.06099,11250.0%0.0%
16.67%66.41,29611,7290.0%25.0%
50.00%62.55047,79333.3%66.7%
50.00%65.174711,02050.0%50.0%
50.00%64.074711,6620.0%75.0%
66.67%66.681210,43333.3%100.0%
50.00%67.51,0758,71275.0%0.0%
20.00%56.875812,3970.0%25.0%
40.00%51.163510,50450.0%33.3%
60.00%53.85758,10050.0%100.0%
40.00%56.389511,9030.0%50.0%
20.00%52.26709,8590.0%33.3%
40.00%51.46769,8700.0%50.0%

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Annie vs Nautilus - Frequently Asked Questions

How does Annie do against Nautilus in League of Legends?

Nautilus wins the Annie vs Nautilus matchup with a 66.7% win rate compared to Annie's 33.3%, a 33.3 percentage point difference. This data is based on 6 recent ranked games in patch 26.12.

How does Annie do against Nautilus in the early game?

In the early game, Annie has the advantage against Nautilus with a 50.0% win rate versus 50.0%. Annie players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Annie do against Nautilus in the late game?

In the late game, Nautilus takes over the Annie vs Nautilus matchup with a 100.0% win rate compared to 0.0%. Nautilus scales better into team fights and objective contests after 25 minutes.

Who wins the Annie vs Nautilus matchup?

Nautilus wins the matchup against Annie with a 66.7% win rate in League of Legends patch 26.12. The 33.3 percentage point advantage means Nautilus is significantly favored in this lane matchup based on 6 games analyzed.

What is the best Annie build against Nautilus?

The best Annie build against Nautilus includes Liandry's Torment, Malignance, Rabadon's Deathcap with Ionian Boots of Lucidity. Check the matchup breakdown above for the full item path and build order.

What are the best Annie runes against Nautilus?

The best Annie runes against Nautilus use the Domination primary tree with Sorcery secondary. This rune setup achieves a 100.0% win rate in the Annie vs Nautilus matchup. See the full rune breakdown in the matchup comparison above.

Does Annie counter Nautilus?

No, Annie struggles against Nautilus with only a 33.3% win rate. Nautilus has the advantage in this matchup. Annie players should focus on safe farming and avoiding extended trades to minimize Nautilus's lead.

How do I play Annie against Nautilus?

When playing Annie against Nautilus, play cautiously and avoid Nautilus's power spikes. Look for jungle assistance and team-dependent plays since Nautilus has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.