
Vaynevs Annie
Vayne vs Annie is a decisive matchup in LoL patch 26.11. Annie wins with a 71.4% win rate (+42.9%) over Vayne based on 7 games. Annie holds the advantage in both the early and late game. Below you'll find the best Vayne build, runes, laning stats, and strategies for the Vayne vs Annie matchup.
Vayne Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Vayne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Vayne vs Annie Matchup?

Vayne vs Annie Matchup Summary
The Vayne vs Annie matchup is a decisive matchup in League of Legends ranked play. Based on 7 recent matches analyzed, Annie wins with a 71.4% win rate compared to Vayne's 28.6%, giving Annie a 42.9 percentage point advantage. Annie dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Vayne players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Annie leads by 0.7s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Annie has a strong advantage in this matchup. Vayne players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Annie overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Vayne vs Annie Laning Phase Breakdown
Annie is favored during the laning phase against Vayne, winning 4 out of 5 key stat categories. Annie holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.
Best Vayne Build Against Annie
Gunmetal Greaves is the optimal boots choice against Annie, providing the mobility and stats Vayne needs most in this matchup. The top-performing core items for Vayne against Annie are Essence Reaver, Blade of The Ruined King and Stormrazor. This combination gives Vayne an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Vayne vs Annie matchup.
Early Game vs Late Game
Annie dominates the early game (first 15 minutes) with a commanding 100.0% win rate — a 100.0 percentage point lead over Vayne. This lopsided early game means Annie can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Annie is far superior in the late game (25+ minutes), boasting a 60.0% win rate — 20.0 points above Vayne. Extended games heavily favor Annie, whose kit and scaling make them a dominant force in team fights and objective control.
Annie holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Vayne players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.
Best Vayne Runes Against Annie
The Precision and Sorcery rune setup gives Vayne the best tools to compete against Annie in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.
Vayne matchup data for League of Legends patch 26.11. The table below shows Vayne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vayne build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 46.01% | 476 | 6.0 | 789 | 12,875 | 44.3% | 47.4% | |
| 47.20% | 447 | 6.0 | 791 | 12,725 | 45.4% | 48.6% | |
| 46.26% | 428 | 5.7 | 796 | 12,715 | 44.9% | 47.3% | |
| 53.92% | 395 | 6.0 | 857 | 12,968 | 53.2% | 54.6% | |
| 47.85% | 372 | 6.2 | 894 | 13,189 | 46.8% | 48.6% | |
| 52.99% | 351 | 6.2 | 843 | 13,142 | 52.5% | 53.4% | |
| 52.98% | 285 | 6.3 | 904 | 13,456 | 46.2% | 58.8% | |
| 53.90% | 269 | 6.3 | 877 | 13,737 | 48.2% | 58.0% | |
| 52.38% | 189 | 5.9 | 886 | 12,468 | 46.1% | 58.2% | |
| 51.92% | 156 | 6.5 | 913 | 11,989 | 50.0% | 53.4% | |
| 54.30% | 151 | 6.1 | 859 | 13,227 | 58.5% | 51.2% | |
| 50.33% | 151 | 6.1 | 804 | 13,007 | 43.8% | 55.2% | |
| 45.95% | 148 | 5.9 | 780 | 13,603 | 45.3% | 46.3% | |
| 45.38% | 130 | 6.1 | 776 | 13,081 | 38.2% | 50.7% | |
| 47.83% | 115 | 6.4 | 812 | 13,765 | 38.5% | 52.6% | |
| 42.61% | 115 | 6.1 | 781 | 12,082 | 34.0% | 49.2% | |
| 50.88% | 114 | 5.8 | 866 | 12,989 | 41.2% | 58.7% | |
| 45.19% | 104 | 6.4 | 899 | 13,175 | 48.7% | 43.1% | |
| 59.80% | 102 | 6.5 | 854 | 13,189 | 63.5% | 56.0% | |
| 31.00% | 100 | 5.5 | 635 | 10,360 | 11.1% | 47.3% | |
| 45.83% | 96 | 5.8 | 857 | 13,164 | 44.4% | 46.7% | |
| 50.53% | 95 | 6.3 | 1,120 | 12,737 | 51.6% | 50.0% | |
| 58.06% | 93 | 6.3 | 796 | 13,008 | 54.8% | 60.8% | |
| 44.09% | 93 | 5.8 | 625 | 11,330 | 42.4% | 45.0% | |
| 45.56% | 90 | 5.8 | 830 | 11,355 | 43.6% | 47.1% | |
| 45.98% | 87 | 6.3 | 851 | 13,572 | 37.9% | 50.0% | |
| 55.81% | 86 | 6.1 | 899 | 10,748 | 43.2% | 65.3% | |
| 55.95% | 84 | 6.2 | 1,292 | 11,546 | 51.4% | 59.2% | |
| 56.41% | 78 | 6.3 | 883 | 13,435 | 57.1% | 55.8% | |
| 54.84% | 62 | 5.9 | 814 | 12,061 | 58.3% | 52.6% | |
| 45.76% | 59 | 6.2 | 877 | 12,775 | 48.0% | 44.1% | |
| 51.92% | 52 | 6.0 | 913 | 11,592 | 48.1% | 56.0% | |
| 45.10% | 51 | 6.5 | 921 | 12,144 | 40.9% | 48.3% | |
| 52.00% | 50 | 6.0 | 875 | 13,621 | 47.8% | 55.6% | |
| 35.42% | 48 | 6.2 | 721 | 10,982 | 28.0% | 43.5% | |
| 58.33% | 48 | 6.1 | 989 | 11,810 | 64.0% | 52.2% | |
| 45.83% | 48 | 6.2 | 1,005 | 10,838 | 51.9% | 38.1% | |
| 50.00% | 46 | 6.2 | 970 | 13,364 | 47.4% | 51.9% | |
| 58.70% | 46 | 6.2 | 914 | 13,671 | 62.5% | 54.5% | |
| 54.55% | 44 | 6.2 | 874 | 14,063 | 57.1% | 53.3% | |
| 44.19% | 43 | 6.6 | 839 | 13,744 | 55.0% | 34.8% | |
| 26.19% | 42 | 5.9 | 874 | 11,678 | 23.5% | 28.0% | |
| 48.78% | 41 | 5.9 | 836 | 11,644 | 43.5% | 55.6% | |
| 52.50% | 40 | 5.6 | 838 | 13,607 | 37.5% | 56.3% | |
| 38.46% | 39 | 6.7 | 854 | 10,961 | 50.0% | 28.6% | |
| 41.03% | 39 | 6.0 | 743 | 9,571 | 28.6% | 55.6% | |
| 67.57% | 37 | 6.5 | 898 | 11,526 | 62.5% | 76.9% | |
| 45.95% | 37 | 5.6 | 832 | 11,998 | 40.0% | 50.0% | |
| 52.94% | 34 | 6.4 | 759 | 12,245 | 50.0% | 54.5% | |
| 52.94% | 34 | 6.4 | 1,051 | 11,474 | 52.6% | 53.3% | |
| 66.67% | 33 | 6.3 | 938 | 13,524 | 61.5% | 70.0% | |
| 48.48% | 33 | 6.4 | 784 | 11,269 | 50.0% | 46.1% | |
| 48.48% | 33 | 6.5 | 979 | 13,305 | 62.5% | 44.0% | |
| 40.63% | 32 | 5.3 | 820 | 11,344 | 42.1% | 38.5% | |
| 62.50% | 32 | 5.7 | 796 | 13,163 | 41.7% | 75.0% | |
| 40.63% | 32 | 6.2 | 676 | 10,369 | 31.6% | 53.9% | |
| 58.06% | 31 | 6.4 | 849 | 12,138 | 64.3% | 52.9% | |
| 53.33% | 30 | 5.6 | 855 | 12,152 | 55.6% | 52.4% | |
| 60.00% | 30 | 6.0 | 953 | 12,308 | 76.9% | 47.1% | |
| 43.33% | 30 | 6.6 | 646 | 11,441 | 37.5% | 50.0% | |
| 55.56% | 27 | 5.3 | 792 | 11,006 | 50.0% | 60.0% | |
| 48.15% | 27 | 6.2 | 834 | 11,465 | 43.8% | 54.5% | |
| 50.00% | 26 | 5.9 | 693 | 11,801 | 41.7% | 57.1% | |
| 50.00% | 26 | 6.1 | 710 | 11,421 | 46.1% | 53.9% | |
| 30.77% | 26 | 5.3 | 700 | 11,001 | 27.3% | 33.3% | |
| 50.00% | 26 | 5.8 | 834 | 12,301 | 54.5% | 46.7% | |
| 48.00% | 25 | 6.0 | 816 | 12,910 | 20.0% | 66.7% | |
| 44.00% | 25 | 6.4 | 758 | 11,844 | 50.0% | 38.5% | |
| 54.17% | 24 | 6.3 | 991 | 12,325 | 64.3% | 40.0% | |
| 45.83% | 24 | 6.0 | 850 | 11,125 | 57.1% | 30.0% | |
| 56.52% | 23 | 5.7 | 610 | 10,299 | 45.5% | 66.7% | |
| 45.45% | 22 | 6.5 | 734 | 12,184 | 38.5% | 55.6% | |
| 40.91% | 22 | 6.0 | 806 | 12,815 | 44.4% | 38.5% | |
| 42.11% | 19 | 6.2 | 920 | 10,372 | 45.5% | 37.5% | |
| 63.16% | 19 | 6.3 | 870 | 12,589 | 50.0% | 72.7% | |
| 42.11% | 19 | 5.8 | 817 | 12,142 | 57.1% | 33.3% | |
| 61.11% | 18 | 5.6 | 1,008 | 13,433 | 66.7% | 58.3% | |
| 62.50% | 16 | 6.1 | 885 | 11,547 | 62.5% | 62.5% | |
| 80.00% | 15 | 2.2 | 885 | 17,368 | 50.0% | 84.6% | |
| 53.33% | 15 | 6.4 | 985 | 13,301 | 50.0% | 54.5% | |
| 60.00% | 15 | 6.5 | 833 | 11,244 | 37.5% | 85.7% | |
| 46.67% | 15 | 6.6 | 876 | 11,530 | 50.0% | 42.9% | |
| 46.67% | 15 | 5.4 | 916 | 13,992 | 25.0% | 54.5% | |
| 42.86% | 14 | 6.4 | 824 | 13,966 | 75.0% | 30.0% | |
| 42.86% | 14 | 6.0 | 841 | 13,447 | 0.0% | 66.7% | |
| 53.85% | 13 | 6.5 | 849 | 13,506 | 100.0% | 33.3% | |
| 46.15% | 13 | 5.2 | 750 | 11,579 | 50.0% | 42.9% | |
| 66.67% | 12 | 5.6 | 1,025 | 12,928 | 80.0% | 57.1% | |
| 33.33% | 12 | 6.0 | 927 | 11,900 | 33.3% | 33.3% | |
| 54.55% | 11 | 5.6 | 1,002 | 13,298 | 50.0% | 57.1% | |
| 63.64% | 11 | 6.1 | 642 | 10,204 | 50.0% | 80.0% | |
| 54.55% | 11 | 2.9 | 820 | 14,068 | 66.7% | 40.0% | |
| 81.82% | 11 | 6.2 | 775 | 12,783 | 100.0% | 71.4% | |
| 54.55% | 11 | 3.4 | 846 | 13,743 | 33.3% | 62.5% | |
| 54.55% | 11 | 5.5 | 761 | 11,649 | 71.4% | 25.0% | |
| 45.45% | 11 | 5.6 | 915 | 9,808 | 75.0% | 28.6% | |
| 40.00% | 10 | 4.6 | 708 | 11,732 | 50.0% | 25.0% | |
| 60.00% | 10 | 5.7 | 820 | 12,597 | 50.0% | 62.5% | |
| 50.00% | 10 | 3.8 | 771 | 13,237 | 33.3% | 57.1% | |
| 40.00% | 10 | 5.5 | 926 | 11,893 | 40.0% | 40.0% | |
| 66.67% | 9 | 3.8 | 1,039 | 13,798 | 66.7% | 66.7% | |
| 33.33% | 9 | 6.1 | 1,076 | 13,273 | 0.0% | 50.0% | |
| 55.56% | 9 | 6.7 | 930 | 13,145 | 100.0% | 20.0% | |
| 33.33% | 9 | 6.0 | 855 | 13,018 | 33.3% | 33.3% | |
| 55.56% | 9 | 3.9 | 860 | 12,860 | 33.3% | 66.7% | |
| 50.00% | 8 | 5.8 | 870 | 14,565 | 50.0% | 50.0% | |
| 62.50% | 8 | 7.3 | 684 | 11,847 | 66.7% | 50.0% | |
| 50.00% | 8 | 3.2 | 883 | 13,479 | 75.0% | 25.0% | |
| 25.00% | 8 | 5.2 | 690 | 9,102 | 16.7% | 50.0% | |
| 37.50% | 8 | 5.8 | 526 | 9,894 | 50.0% | 25.0% | |
| 57.14% | 7 | 4.0 | 760 | 10,750 | 33.3% | 75.0% | |
| 71.43% | 7 | 3.6 | 743 | 11,425 | 80.0% | 50.0% | |
| 42.86% | 7 | 4.5 | 723 | 11,697 | 33.3% | 50.0% | |
| 28.57% | 7 | 4.5 | 676 | 12,046 | 0.0% | 40.0% | |
| 50.00% | 6 | 3.5 | 781 | 15,022 | 0.0% | 60.0% | |
| 33.33% | 6 | 6.8 | 823 | 13,779 | 0.0% | 50.0% | |
| 33.33% | 6 | 2.9 | 989 | 12,898 | 33.3% | 33.3% | |
| 66.67% | 6 | 5.9 | 1,006 | 14,143 | 50.0% | 75.0% | |
| 20.00% | 5 | 4.7 | 577 | 8,999 | 33.3% | 0.0% | |
| 40.00% | 5 | 2.1 | 611 | 12,290 | 50.0% | 0.0% | |
| 40.00% | 5 | 6.4 | 1,176 | 14,594 | 0.0% | 50.0% | |
| 80.00% | 5 | 6.2 | 1,024 | 13,762 | 100.0% | 66.7% | |
| 40.00% | 5 | 5.9 | 962 | 13,248 | 0.0% | 50.0% | |
| 40.00% | 5 | 6.0 | 673 | 9,218 | 50.0% | 0.0% | |
| 40.00% | 5 | 6.4 | 726 | 9,892 | 40.0% | 0.0% | |
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Vayne vs Annie - Frequently Asked Questions
How does Vayne do against Annie in League of Legends?
Annie wins the Vayne vs Annie matchup with a 71.4% win rate compared to Vayne's 28.6%, a 42.9 percentage point difference. This data is based on 7 recent ranked games in patch 26.11.
How does Vayne do against Annie in the early game?
In the early game, Annie has the advantage against Vayne with a 100.0% win rate versus 0.0%. Annie players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Vayne do against Annie in the late game?
In the late game, Annie takes over the Vayne vs Annie matchup with a 60.0% win rate compared to 40.0%. Annie scales better into team fights and objective contests after 25 minutes.
Who wins the Vayne vs Annie matchup?
Annie wins the matchup against Vayne with a 71.4% win rate in League of Legends patch 26.11. The 42.9 percentage point advantage means Annie is significantly favored in this lane matchup based on 7 games analyzed.
What is the best Vayne build against Annie?
The best Vayne build against Annie includes Essence Reaver, Blade of The Ruined King, Stormrazor with Gunmetal Greaves. Check the matchup breakdown above for the full item path and build order.
What are the best Vayne runes against Annie?
The best Vayne runes against Annie use the Precision primary tree with Sorcery secondary. This rune setup achieves a 100.0% win rate in the Vayne vs Annie matchup. See the full rune breakdown in the matchup comparison above.
Does Vayne counter Annie?
No, Vayne struggles against Annie with only a 28.6% win rate. Annie has the advantage in this matchup. Vayne players should focus on safe farming and avoiding extended trades to minimize Annie's lead.
How do I play Vayne against Annie?
When playing Vayne against Annie, play cautiously and avoid Annie's power spikes. Look for jungle assistance and team-dependent plays since Annie has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.
