
Karmavs Karthus
Karma vs Karthus is a decisive matchup in LoL patch 26.10. Karma wins with a 60.0% win rate (+20.0%) over Karthus based on 5 games. Karthus wins the early laning phase while Karma scales better into the late game. Below you'll find the best Karma build, runes, laning stats, and strategies for the Karma vs Karthus matchup.
Karma Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Karma performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Karma vs Karthus Matchup?

Karma vs Karthus Matchup Summary
The Karma vs Karthus matchup is a decisive matchup in League of Legends ranked play. Based on 5 recent matches analyzed, Karma wins with a 60.0% win rate compared to Karthus's 40.0%, giving Karma a 20.0 percentage point advantage. Game phase dynamics play a critical role here: Karthus controls the early laning stage, but Karma outscales as the game goes longer. The matchup shifts dramatically depending on game length — Karthus needs to press advantages before Karma reaches their power spikes, while Karma should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in damage output, where Karthus leads by 492 DMG/min — a difference that heavily influences the outcome of trades and skirmishes. Karma players can confidently pick into Karthus and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Karthus away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Karma vs Karthus Laning Phase Breakdown
Karthus is favored during the laning phase against Karma, winning 4 out of 5 key stat categories. Karthus holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.
Best Karma Build Against Karthus
Ionian Boots of Lucidity is the optimal boots choice against Karthus, providing the mobility and stats Karma needs most in this matchup. The top-performing core items for Karma against Karthus are Echoes of Helia, Moonstone Renewer and Morellonomicon. This combination gives Karma an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Karthus. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Karma vs Karthus matchup.
Early Game vs Late Game
Karthus dominates the early game (first 15 minutes) with a commanding 100.0% win rate — a 100.0 percentage point lead over Karma. This lopsided early game means Karthus can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Karma is far superior in the late game (25+ minutes), boasting a 75.0% win rate — 50.0 points above Karthus. Extended games heavily favor Karma, whose kit and scaling make them a dominant force in team fights and objective control.
This matchup features a dramatic power shift: Karthus must aggressively press their early advantage and close out the game before Karma reaches their scaling breakpoints. If Karma survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.
Best Karma Runes Against Karthus
Running Sorcery primary with Resolve secondary allows Karma to press their advantage against Karthus, amplifying the strengths that make this a favorable matchup.
Karma matchup data for League of Legends patch 26.10. The table below shows Karma's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Karma build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 50.30% | 331 | 1.3 | 375 | 8,680 | 43.3% | 55.6% | |
| 49.07% | 322 | 1.2 | 367 | 8,299 | 47.1% | 50.9% | |
| 47.74% | 243 | 1.3 | 394 | 8,798 | 41.6% | 52.1% | |
| 46.12% | 232 | 1.2 | 406 | 8,366 | 51.4% | 41.3% | |
| 59.13% | 230 | 1.5 | 383 | 8,957 | 55.6% | 61.4% | |
| 50.28% | 179 | 1.3 | 389 | 8,846 | 51.3% | 49.5% | |
| 47.79% | 136 | 1.4 | 408 | 8,998 | 46.4% | 48.8% | |
| 40.74% | 135 | 1.2 | 372 | 8,144 | 45.0% | 37.3% | |
| 54.14% | 133 | 1.4 | 389 | 8,611 | 58.7% | 50.0% | |
| 40.16% | 127 | 1.2 | 370 | 8,819 | 32.1% | 46.5% | |
| 51.59% | 126 | 1.3 | 442 | 8,763 | 55.7% | 47.7% | |
| 43.20% | 125 | 1.3 | 396 | 8,156 | 51.7% | 35.4% | |
| 47.97% | 123 | 1.3 | 422 | 8,472 | 46.1% | 49.3% | |
| 53.21% | 109 | 1.2 | 403 | 8,815 | 50.0% | 56.4% | |
| 49.53% | 107 | 1.3 | 376 | 8,945 | 54.8% | 46.1% | |
| 46.67% | 105 | 1.2 | 342 | 8,621 | 40.9% | 50.8% | |
| 43.82% | 89 | 1.3 | 424 | 8,374 | 48.8% | 39.6% | |
| 55.68% | 88 | 1.3 | 327 | 8,889 | 65.0% | 47.9% | |
| 53.41% | 88 | 1.4 | 357 | 9,367 | 60.7% | 50.0% | |
| 51.16% | 86 | 1.3 | 401 | 8,365 | 50.0% | 52.3% | |
| 53.09% | 81 | 1.2 | 396 | 8,830 | 50.0% | 55.8% | |
| 41.56% | 77 | 1.4 | 439 | 8,197 | 47.4% | 35.9% | |
| 51.32% | 76 | 1.4 | 357 | 8,594 | 42.4% | 58.1% | |
| 45.45% | 66 | 1.2 | 367 | 8,681 | 37.0% | 51.3% | |
| 49.18% | 61 | 1.2 | 375 | 7,792 | 48.6% | 50.0% | |
| 50.82% | 61 | 1.2 | 390 | 8,475 | 53.3% | 48.4% | |
| 49.09% | 55 | 1.1 | 436 | 8,331 | 55.6% | 42.9% | |
| 39.22% | 51 | 1.3 | 410 | 8,566 | 59.1% | 24.1% | |
| 43.18% | 44 | 1.2 | 357 | 8,072 | 40.0% | 47.4% | |
| 52.27% | 44 | 1.8 | 496 | 8,325 | 58.3% | 45.0% | |
| 48.84% | 43 | 1.4 | 381 | 8,490 | 59.1% | 38.1% | |
| 56.41% | 39 | 1.2 | 387 | 9,427 | 25.0% | 70.4% | |
| 37.14% | 35 | 2.4 | 403 | 9,435 | 66.7% | 21.7% | |
| 46.15% | 26 | 1.4 | 429 | 8,531 | 52.9% | 33.3% | |
| 60.00% | 25 | 1.1 | 404 | 8,570 | 58.3% | 61.5% | |
| 40.00% | 25 | 2.1 | 431 | 8,356 | 23.1% | 58.3% | |
| 50.00% | 22 | 1.2 | 399 | 8,022 | 61.5% | 33.3% | |
| 40.91% | 22 | 2.4 | 445 | 7,831 | 30.8% | 55.6% | |
| 50.00% | 22 | 1.1 | 375 | 8,190 | 54.5% | 45.5% | |
| 52.38% | 21 | 2.3 | 474 | 9,372 | 36.4% | 70.0% | |
| 47.37% | 19 | 2.5 | 468 | 10,330 | 62.5% | 36.4% | |
| 55.56% | 18 | 2.1 | 482 | 8,985 | 66.7% | 44.4% | |
| 61.11% | 18 | 1.4 | 458 | 8,788 | 50.0% | 75.0% | |
| 22.22% | 18 | 2.5 | 501 | 9,300 | 28.6% | 18.2% | |
| 53.33% | 15 | 3.2 | 445 | 8,964 | 57.1% | 50.0% | |
| 53.33% | 15 | 1.7 | 363 | 7,904 | 44.4% | 66.7% | |
| 53.33% | 15 | 5.3 | 697 | 10,384 | 66.7% | 33.3% | |
| 35.71% | 14 | 2.9 | 494 | 8,795 | 37.5% | 33.3% | |
| 61.54% | 13 | 1.1 | 391 | 7,603 | 70.0% | 33.3% | |
| 66.67% | 12 | 1.8 | 418 | 8,714 | 62.5% | 75.0% | |
| 45.45% | 11 | 4.5 | 508 | 9,638 | 50.0% | 42.9% | |
| 54.55% | 11 | 5.5 | 683 | 10,587 | 66.7% | 50.0% | |
| 63.64% | 11 | 3.4 | 678 | 11,043 | 33.3% | 75.0% | |
| 30.00% | 10 | 3.4 | 607 | 10,050 | 25.0% | 33.3% | |
| 60.00% | 10 | 1.9 | 482 | 9,823 | 66.7% | 57.1% | |
| 55.56% | 9 | 5.1 | 774 | 10,712 | 50.0% | 60.0% | |
| 33.33% | 9 | 1.0 | 244 | 6,505 | 33.3% | 33.3% | |
| 22.22% | 9 | 4.6 | 607 | 8,306 | 14.3% | 50.0% | |
| 50.00% | 8 | 5.8 | 825 | 10,616 | 40.0% | 66.7% | |
| 50.00% | 8 | 2.2 | 492 | 7,263 | 50.0% | 50.0% | |
| 62.50% | 8 | 2.9 | 598 | 11,381 | 100.0% | 57.1% | |
| 37.50% | 8 | 6.4 | 754 | 8,855 | 25.0% | 50.0% | |
| 37.50% | 8 | 1.9 | 545 | 10,654 | 100.0% | 28.6% | |
| 62.50% | 8 | 1.7 | 557 | 10,729 | 50.0% | 66.7% | |
| 57.14% | 7 | 4.7 | 685 | 7,016 | 57.1% | 0.0% | |
| 42.86% | 7 | 5.5 | 741 | 9,477 | 33.3% | 50.0% | |
| 42.86% | 7 | 4.9 | 870 | 12,359 | 0.0% | 42.9% | |
| 42.86% | 7 | 1.2 | 375 | 9,559 | 50.0% | 40.0% | |
| 42.86% | 7 | 5.2 | 739 | 10,684 | 33.3% | 50.0% | |
| 42.86% | 7 | 5.3 | 713 | 12,233 | 0.0% | 50.0% | |
| 33.33% | 6 | 2.7 | 686 | 8,853 | 25.0% | 50.0% | |
| 100.00% | 6 | 5.1 | 774 | 7,042 | 100.0% | 100.0% | |
| 50.00% | 6 | 2.2 | 431 | 9,291 | 0.0% | 75.0% | |
| 50.00% | 6 | 5.3 | 720 | 10,847 | 100.0% | 40.0% | |
| 33.33% | 6 | 5.7 | 612 | 9,065 | 0.0% | 50.0% | |
| 40.00% | 5 | 1.1 | 264 | 5,923 | 66.7% | 0.0% | |
| 0.00% | 5 | 3.5 | 635 | 8,455 | 0.0% | 0.0% | |
| 60.00% | 5 | 1.1 | 331 | 10,388 | 0.0% | 75.0% | |
| 80.00% | 5 | 1.0 | 337 | 9,172 | 0.0% | 100.0% | |
| 60.00% | 5 | 2.2 | 393 | 8,677 | 66.7% | 50.0% | |
| 60.00% | 5 | 3.9 | 536 | 11,434 | 50.0% | 66.7% | |
| 60.00% | 5 | 1.3 | 629 | 11,789 | 0.0% | 60.0% | |
| 20.00% | 5 | 1.2 | 379 | 9,596 | 0.0% | 33.3% | |
| 60.00% | 5 | 5.9 | 633 | 8,431 | 50.0% | 66.7% | |
| 60.00% | 5 | 1.2 | 405 | 9,460 | 100.0% | 50.0% | |
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Karma vs Karthus - Frequently Asked Questions
How does Karma do against Karthus in League of Legends?
Karma wins the Karma vs Karthus matchup with a 60.0% win rate compared to Karthus's 40.0%, a 20.0 percentage point difference. This data is based on 5 recent ranked games in patch 26.10.
How does Karma do against Karthus in the early game?
In the early game, Karthus has the advantage against Karma with a 100.0% win rate versus 0.0%. Karthus players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Karma do against Karthus in the late game?
In the late game, Karma takes over the Karma vs Karthus matchup with a 75.0% win rate compared to 25.0%. Karma scales better into team fights and objective contests after 25 minutes.
Who wins the Karma vs Karthus matchup?
Karma wins the matchup against Karthus with a 60.0% win rate in League of Legends patch 26.10. The 20.0 percentage point advantage means Karma is significantly favored in this lane matchup based on 5 games analyzed.
What is the best Karma build against Karthus?
The best Karma build against Karthus includes Echoes of Helia, Moonstone Renewer, Morellonomicon with Ionian Boots of Lucidity. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.
What are the best Karma runes against Karthus?
The best Karma runes against Karthus use the Sorcery primary tree with Resolve secondary. This rune setup achieves a 100.0% win rate in the Karma vs Karthus matchup. See the full rune breakdown in the matchup comparison above.
Does Karma counter Karthus?
Yes, Karma has a favorable matchup against Karthus with a 60.0% win rate. Karma strongly counters Karthus in lane based on current patch 26.10 data.
How do I play Karma against Karthus?
When playing Karma against Karthus, leverage your statistical advantages by trading aggressively during favorable windows. Play safe early and scale into your power spikes where you outperform Karthus. Build the recommended items and runes for this specific matchup for the best results.
