Karma - League of Legends Champion
Win Rate
49.0%
Pick Rate
2.3%

Karmavs Karthus

DMageSupport
Patch26.10
Matches1,926,417
LaneAll Lanes
TierAll Tiers
Last UpdatedMay 20, 2026
MethodologyData Methodology

Karma vs Karthus is a decisive matchup in LoL patch 26.10. Karma wins with a 60.0% win rate (+20.0%) over Karthus based on 5 games. Karthus wins the early laning phase while Karma scales better into the late game. Below you'll find the best Karma build, runes, laning stats, and strategies for the Karma vs Karthus matchup.

Karma Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Karma performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Karthus - 60.0% win rateKarthus(60.0%)
Karma - 60.0% win rate in this matchup
Karma
60.0% WR
VS
Karthus vs Karma matchup - 40.0% win rate
Karthus
40.0% WR

Who Wins the Karma vs Karthus Matchup?

Karma wins the Karma vs Karthus matchup
Winner
Karma
Matches: 5
60.0%
Win Rate
40.0%
1.1
CS / min
2.4
331
DMG / min
823
10,388
Gold / game
11,731
244
Heal / min
66
383
DMG Mitigated / min
320
0.8
CC / min
0.9
0.0%
Early Game WR
100.0%
75.0%
Late Game WR
25.0%

Karma vs Karthus Matchup Summary

The Karma vs Karthus matchup is a decisive matchup in League of Legends ranked play. Based on 5 recent matches analyzed, Karma wins with a 60.0% win rate compared to Karthus's 40.0%, giving Karma a 20.0 percentage point advantage. Game phase dynamics play a critical role here: Karthus controls the early laning stage, but Karma outscales as the game goes longer. The matchup shifts dramatically depending on game length — Karthus needs to press advantages before Karma reaches their power spikes, while Karma should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in damage output, where Karthus leads by 492 DMG/min — a difference that heavily influences the outcome of trades and skirmishes. Karma players can confidently pick into Karthus and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Karthus away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Karma vs Karthus Laning Phase Breakdown

Karthus wins the laning phase against Karma in League of Legends

Karthus is favored during the laning phase against Karma, winning 4 out of 5 key stat categories. Karthus holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.

Farming
1.1Karma
2.4Karthus
Karthus significantly out-farms Karma by 1.3 CS per minute, accumulating an estimated 19 CS lead by mid game. This substantial farming gap gives Karthus a major gold advantage and earlier item completions. Karma players should prioritize wave management techniques like freezing near tower and using abilities efficiently to minimize the deficit.
Damage
331Karma
823Karthus
Karthus heavily out-damages Karma by 492 DMG/min, dominating both short trades and all-in fights. Karma should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Karthus's sustained damage advantage take over.
Economy
10,388Karma
11,731Karthus
Karthus generates a commanding 1,343 more gold per game than Karma. This substantial economic advantage means Karthus consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Karma should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.8Karma
0.9Karthus
Both Karma and Karthus provide similar amounts of crowd control (0.0s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
627Karma
386Karthus
Karma vastly out-sustains Karthus, healing and mitigating 241 more damage per minute. This massive durability gap means Karma can absorb significant punishment and remain in lane while Karthus is forced to recall. Building grievous wounds early is essential for Karthus, and focusing on burst trade patterns rather than sustained fights is critical.

Best Karma Build Against Karthus

Ionian Boots of Lucidity is the optimal boots choice against Karthus, providing the mobility and stats Karma needs most in this matchup. The top-performing core items for Karma against Karthus are Echoes of Helia, Moonstone Renewer and Morellonomicon. This combination gives Karma an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Karthus. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Karma vs Karthus matchup.

Early Game vs Late Game

Early Game
Karthus
100.0%
+100.0% advantage
Karma early game win rateKarma0.0%
Karthus early game win rateKarthus100.0%
Late Game
Karma
75.0%
+50.0% advantage
Karma late game win rateKarma75.0%
Karthus late game win rateKarthus25.0%

Karthus dominates the early game (first 15 minutes) with a commanding 100.0% win rate — a 100.0 percentage point lead over Karma. This lopsided early game means Karthus can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Karma is far superior in the late game (25+ minutes), boasting a 75.0% win rate — 50.0 points above Karthus. Extended games heavily favor Karma, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Karthus must aggressively press their early advantage and close out the game before Karma reaches their scaling breakpoints. If Karma survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Karma Runes Against Karthus

Sorcery rune tree - Karma primary runes vs KarthusSorcery
Arcane Comet - best Karma rune vs KarthusManaflow Band - best Karma rune vs KarthusTranscendence - best Karma rune vs KarthusScorch - best Karma rune vs Karthus
Resolve rune tree - Karma secondary runes vs KarthusResolve
Revitalize - best Karma rune vs KarthusFont of Life - best Karma rune vs Karthus
100.0% WR

Running Sorcery primary with Resolve secondary allows Karma to press their advantage against Karthus, amplifying the strengths that make this a favorable matchup.


Karma matchup data for League of Legends patch 26.10. The table below shows Karma's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Karma build, runes, laning stats, and early vs late game analysis for that specific matchup.

Karma matchup win rates and stats in League of Legends patch 26.10
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
50.30%3311.33758,68043.3%55.6%
49.07%3221.23678,29947.1%50.9%
47.74%2431.33948,79841.6%52.1%
46.12%2321.24068,36651.4%41.3%
59.13%2301.53838,95755.6%61.4%
50.28%1791.33898,84651.3%49.5%
47.79%1361.44088,99846.4%48.8%
40.74%1351.23728,14445.0%37.3%
54.14%1331.43898,61158.7%50.0%
40.16%1271.23708,81932.1%46.5%
51.59%1261.34428,76355.7%47.7%
43.20%1251.33968,15651.7%35.4%
47.97%1231.34228,47246.1%49.3%
53.21%1091.24038,81550.0%56.4%
49.53%1071.33768,94554.8%46.1%
46.67%1051.23428,62140.9%50.8%
43.82%891.34248,37448.8%39.6%
55.68%881.33278,88965.0%47.9%
53.41%881.43579,36760.7%50.0%
51.16%861.34018,36550.0%52.3%
53.09%811.23968,83050.0%55.8%
41.56%771.44398,19747.4%35.9%
51.32%761.43578,59442.4%58.1%
45.45%661.23678,68137.0%51.3%
49.18%611.23757,79248.6%50.0%
50.82%611.23908,47553.3%48.4%
49.09%551.14368,33155.6%42.9%
39.22%511.34108,56659.1%24.1%
43.18%441.23578,07240.0%47.4%
52.27%441.84968,32558.3%45.0%
48.84%431.43818,49059.1%38.1%
56.41%391.23879,42725.0%70.4%
37.14%352.44039,43566.7%21.7%
46.15%261.44298,53152.9%33.3%
60.00%251.14048,57058.3%61.5%
40.00%252.14318,35623.1%58.3%
50.00%221.23998,02261.5%33.3%
40.91%222.44457,83130.8%55.6%
50.00%221.13758,19054.5%45.5%
52.38%212.34749,37236.4%70.0%
47.37%192.546810,33062.5%36.4%
55.56%182.14828,98566.7%44.4%
61.11%181.44588,78850.0%75.0%
22.22%182.55019,30028.6%18.2%
53.33%153.24458,96457.1%50.0%
53.33%151.73637,90444.4%66.7%
53.33%155.369710,38466.7%33.3%
35.71%142.94948,79537.5%33.3%
61.54%131.13917,60370.0%33.3%
66.67%121.84188,71462.5%75.0%
45.45%114.55089,63850.0%42.9%
54.55%115.568310,58766.7%50.0%
63.64%113.467811,04333.3%75.0%
30.00%103.460710,05025.0%33.3%
60.00%101.94829,82366.7%57.1%
55.56%95.177410,71250.0%60.0%
33.33%91.02446,50533.3%33.3%
22.22%94.66078,30614.3%50.0%
50.00%85.882510,61640.0%66.7%
50.00%82.24927,26350.0%50.0%
62.50%82.959811,381100.0%57.1%
37.50%86.47548,85525.0%50.0%
37.50%81.954510,654100.0%28.6%
62.50%81.755710,72950.0%66.7%
57.14%74.76857,01657.1%0.0%
42.86%75.57419,47733.3%50.0%
42.86%74.987012,3590.0%42.9%
42.86%71.23759,55950.0%40.0%
42.86%75.273910,68433.3%50.0%
42.86%75.371312,2330.0%50.0%
33.33%62.76868,85325.0%50.0%
100.00%65.17747,042100.0%100.0%
50.00%62.24319,2910.0%75.0%
50.00%65.372010,847100.0%40.0%
33.33%65.76129,0650.0%50.0%
40.00%51.12645,92366.7%0.0%
0.00%53.56358,4550.0%0.0%
60.00%51.133110,3880.0%75.0%
80.00%51.03379,1720.0%100.0%
60.00%52.23938,67766.7%50.0%
60.00%53.953611,43450.0%66.7%
60.00%51.362911,7890.0%60.0%
20.00%51.23799,5960.0%33.3%
60.00%55.96338,43150.0%66.7%
60.00%51.24059,460100.0%50.0%

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Karma vs Karthus - Frequently Asked Questions

How does Karma do against Karthus in League of Legends?

Karma wins the Karma vs Karthus matchup with a 60.0% win rate compared to Karthus's 40.0%, a 20.0 percentage point difference. This data is based on 5 recent ranked games in patch 26.10.

How does Karma do against Karthus in the early game?

In the early game, Karthus has the advantage against Karma with a 100.0% win rate versus 0.0%. Karthus players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Karma do against Karthus in the late game?

In the late game, Karma takes over the Karma vs Karthus matchup with a 75.0% win rate compared to 25.0%. Karma scales better into team fights and objective contests after 25 minutes.

Who wins the Karma vs Karthus matchup?

Karma wins the matchup against Karthus with a 60.0% win rate in League of Legends patch 26.10. The 20.0 percentage point advantage means Karma is significantly favored in this lane matchup based on 5 games analyzed.

What is the best Karma build against Karthus?

The best Karma build against Karthus includes Echoes of Helia, Moonstone Renewer, Morellonomicon with Ionian Boots of Lucidity. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Karma runes against Karthus?

The best Karma runes against Karthus use the Sorcery primary tree with Resolve secondary. This rune setup achieves a 100.0% win rate in the Karma vs Karthus matchup. See the full rune breakdown in the matchup comparison above.

Does Karma counter Karthus?

Yes, Karma has a favorable matchup against Karthus with a 60.0% win rate. Karma strongly counters Karthus in lane based on current patch 26.10 data.

How do I play Karma against Karthus?

When playing Karma against Karthus, leverage your statistical advantages by trading aggressively during favorable windows. Play safe early and scale into your power spikes where you outperform Karthus. Build the recommended items and runes for this specific matchup for the best results.