Seraphine - League of Legends Champion
Win Rate
50.9%
Pick Rate
4.9%

Seraphinevs Karma

ASupportMage
Patch26.7
Matches949,984
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 20, 2026
MethodologyData Methodology

Seraphine vs Karma is a moderate matchup in LoL patch 26.7. Seraphine wins with a 51.5% win rate (+2.9%) over Karma based on 138 games. Seraphine holds the advantage in both the early and late game. Below you'll find the best Seraphine build, runes, laning stats, and strategies for the Seraphine vs Karma matchup.

Seraphine Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Seraphine performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Karma - 51.5% win rateKarma(51.5%)
Seraphine - 51.5% win rate in this matchup
Seraphine
51.5% WR
VS
Karma vs Seraphine matchup - 48.5% win rate
Karma
48.5% WR

Who Wins the Seraphine vs Karma Matchup?

Seraphine wins the Seraphine vs Karma matchup
Winner
Seraphine
Matches: 138
51.5%
Win Rate
48.5%
1.4
CS / min
1.3
410
DMG / min
366
8,924
Gold / game
8,616
367
Heal / min
230
352
DMG Mitigated / min
450
1.1
CC / min
0.9
50.8%
Early Game WR
49.3%
52.1%
Late Game WR
47.9%

Seraphine vs Karma Matchup Summary

The Seraphine vs Karma matchup is a very close matchup in League of Legends ranked play. Based on 138 recent matches analyzed, Seraphine wins with a 51.5% win rate compared to Karma's 48.5%, giving Seraphine a 2.9 percentage point advantage. Seraphine holds a slight edge in both the early and late game, but the margins are thin enough that individual skill and jungle attention will often determine the outcome. Karma can still find windows through outplays and team coordination. The most significant statistical gap is in crowd control, where Seraphine leads by 0.2s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Seraphine has a statistical edge, but the margin is close enough that respecting Karma's strengths is important. Trade when cooldowns are favorable, track the enemy jungler, and build toward your strongest item spikes to convert the slight advantage into a decisive lead. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Seraphine vs Karma Laning Phase Breakdown

Seraphine wins the laning phase against Karma in League of Legends

Seraphine is favored during the laning phase against Karma, winning 5 out of 5 key stat categories. Seraphine holds advantages in farming, damage, gold income, crowd control and sustain, making them the stronger laner in this matchup.

Farming
1.4Seraphine
1.3Karma
Seraphine and Karma farm at nearly identical rates in this matchup, with only a 0.1 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
410Seraphine
366Karma
Seraphine deals 44 more champion damage per minute than Karma. While noticeable in extended trades, this gap can be offset by Karma choosing favorable fight windows, such as engaging when Seraphine's key abilities are on cooldown or trading immediately after dodging a skillshot.
Economy
8,924Seraphine
8,616Karma
Seraphine earns 308 more gold per game than Karma, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Seraphine slightly faster item completions.
Utility
1.1Seraphine
0.9Karma
Both Seraphine and Karma provide similar amounts of crowd control (0.2s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
718Seraphine
680Karma
Seraphine and Karma have comparable sustain profiles, with only 38 HP/min separating their healing and damage mitigation. Neither champion can out-attrition the other in lane, so trades will be decided by burst potential and ability usage rather than sustain.

Best Seraphine Build Against Karma

Ionian Boots of Lucidity is the optimal boots choice against Karma, providing the mobility and stats Seraphine needs most in this matchup. The top-performing core items for Seraphine against Karma are Echoes of Helia, Moonstone Renewer and Diadem of Songs. This combination gives Seraphine an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 64.3% win rate across 14 games — well above average and making it the top item path against Karma. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Seraphine vs Karma matchup.

Early Game vs Late Game

Early Game
Seraphine
50.8%
+1.5% advantage
Seraphine early game win rateSeraphine50.8%
Karma early game win rateKarma49.3%
Late Game
Seraphine
52.1%
+4.2% advantage
Seraphine late game win rateSeraphine52.1%
Karma late game win rateKarma47.9%

The early game (first 15 minutes) is a toss-up between Seraphine and Karma, with Seraphine holding a razor-thin 50.8% win rate edge (+1.5%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.

In the late game (25+ minutes), Seraphine takes over with a 52.1% win rate, leading Karma by 4.2 percentage points. Seraphine scales more effectively into team fights and objective contests.

Seraphine holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Karma players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Seraphine Runes Against Karma

Sorcery rune tree - Seraphine primary runes vs KarmaSorcery
Arcane Comet - best Seraphine rune vs KarmaManaflow Band - best Seraphine rune vs KarmaTranscendence - best Seraphine rune vs KarmaScorch - best Seraphine rune vs Karma
Inspiration rune tree - Seraphine secondary runes vs KarmaInspiration
Biscuit Delivery - best Seraphine rune vs KarmaCosmic Insight - best Seraphine rune vs Karma
61.5% WR

The Sorcery primary with Inspiration secondary combination helps Seraphine maximize their potential in this closely contested matchup, providing the right mix of offensive and defensive tools to edge out Karma.


Seraphine matchup data for League of Legends patch 26.7. The table below shows Seraphine's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Seraphine build, runes, laning stats, and early vs late game analysis for that specific matchup.

Seraphine matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
54.18%2991.64439,72745.0%59.6%
44.49%2631.34388,73041.4%48.0%
53.94%2411.34619,24352.6%55.2%
53.01%1831.44589,30748.8%56.4%
53.59%1811.44469,09849.4%57.5%
53.66%1641.44779,15159.3%48.2%
51.57%1591.54879,18454.3%49.4%
56.96%1581.44609,12365.1%51.6%
51.45%1381.44108,92450.8%52.1%
57.58%1321.44559,01657.4%57.8%
44.44%1261.34078,50942.9%46.0%
48.72%1171.655210,13343.2%51.3%
55.17%1161.54939,75339.1%65.7%
48.28%1161.754110,06752.2%45.7%
54.29%1051.34268,52558.2%50.0%
47.57%1031.54449,60136.6%54.8%
53.92%1021.44648,93753.9%54.0%
50.50%1011.43578,58654.9%46.0%
65.31%982.04699,74265.0%65.5%
51.11%901.45449,00546.1%54.9%
60.67%891.45258,87651.2%69.6%
48.05%771.64329,06447.1%48.8%
48.48%661.64499,83052.0%46.3%
56.06%661.446210,05756.0%56.1%
59.09%661.34709,19553.3%63.9%
51.52%661.45339,38642.9%57.9%
50.00%561.34318,78350.0%50.0%
50.91%555.059410,15445.7%60.0%
61.11%541.45039,73561.1%61.1%
45.10%511.45549,19748.0%42.3%
56.00%501.64589,66571.4%44.8%
68.09%471.34338,79683.3%52.2%
41.30%461.44408,44340.7%42.1%
55.26%386.575312,73061.1%50.0%
41.67%361.55229,34566.7%23.8%
45.71%351.45389,51041.2%50.0%
51.43%356.577612,68062.5%42.1%
41.18%341.95239,70342.9%40.0%
62.50%324.466312,14861.5%63.2%
61.54%261.45069,89770.0%56.3%
57.69%265.866912,09666.7%50.0%
72.00%253.654911,21477.8%68.8%
47.83%231.34387,54662.5%14.3%
39.13%231.34279,80042.9%37.5%
45.45%225.768813,31257.1%40.0%
42.86%212.04569,77930.0%54.5%
60.00%206.873212,63062.5%58.3%
68.42%192.25288,37271.4%60.0%
52.63%194.566310,72362.5%45.5%
77.78%185.262111,90780.0%75.0%
50.00%182.23929,53214.3%72.7%
17.65%171.95419,5550.0%30.0%
68.75%166.175711,132100.0%44.4%
56.25%165.061711,17950.0%58.3%
37.50%161.44408,74328.6%44.4%
40.00%155.879112,89180.0%20.0%
53.33%152.65158,83558.3%33.3%
60.00%156.969012,35375.0%42.9%
57.14%141.65038,97662.5%50.0%
50.00%126.066912,17266.7%33.3%
58.33%121.95109,80057.1%60.0%
41.67%124.362911,9680.0%50.0%
50.00%125.572511,57837.5%75.0%
45.45%111.83348,40757.1%25.0%
45.45%111.448611,0260.0%50.0%
20.00%101.94449,6570.0%40.0%
30.00%106.083411,91850.0%16.7%
66.67%95.04869,88271.4%50.0%
66.67%96.791812,31350.0%100.0%
44.44%91.652310,69633.3%50.0%
66.67%95.06849,58460.0%75.0%
55.56%95.878611,74075.0%40.0%
62.50%86.375213,234100.0%50.0%
62.50%84.164710,851100.0%0.0%
62.50%86.072611,59850.0%75.0%
50.00%81.63948,88825.0%75.0%
50.00%82.659011,57450.0%50.0%
37.50%84.34689,60866.7%20.0%
50.00%86.075212,12750.0%50.0%
75.00%81.84619,71750.0%100.0%
50.00%84.75939,70720.0%100.0%
28.57%71.54699,3480.0%50.0%
57.14%72.24578,64566.7%50.0%
85.71%71.55068,91275.0%100.0%
42.86%71.44499,4630.0%60.0%
50.00%63.866510,38850.0%50.0%
50.00%61.253910,07150.0%50.0%
50.00%62.45769,27866.7%33.3%
50.00%65.060611,31766.7%33.3%
40.00%56.077711,01533.3%50.0%
20.00%55.151210,8920.0%25.0%
60.00%55.872310,033100.0%50.0%
20.00%51.43949,2580.0%33.3%
80.00%54.677910,15775.0%100.0%
40.00%52.76589,47233.3%50.0%

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Seraphine vs Karma - Frequently Asked Questions

How does Seraphine do against Karma in League of Legends?

Seraphine wins the Seraphine vs Karma matchup with a 51.5% win rate compared to Karma's 48.5%, a 2.9 percentage point difference. This data is based on 138 recent ranked games in patch 26.7.

How does Seraphine do against Karma in the early game?

In the early game, Seraphine has the advantage against Karma with a 50.8% win rate versus 49.3%. Seraphine players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Seraphine do against Karma in the late game?

In the late game, Seraphine takes over the Seraphine vs Karma matchup with a 52.1% win rate compared to 47.9%. Seraphine scales better into team fights and objective contests after 25 minutes.

Who wins the Seraphine vs Karma matchup?

Seraphine wins the matchup against Karma with a 51.5% win rate in League of Legends patch 26.7. The 2.9 percentage point advantage means Seraphine is moderately favored in this lane matchup based on 138 games analyzed.

What is the best Seraphine build against Karma?

The best Seraphine build against Karma includes Echoes of Helia, Moonstone Renewer, Diadem of Songs with Ionian Boots of Lucidity. This build achieves a 64.3% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Seraphine runes against Karma?

The best Seraphine runes against Karma use the Sorcery primary tree with Inspiration secondary. This rune setup achieves a 61.5% win rate in the Seraphine vs Karma matchup. See the full rune breakdown in the matchup comparison above.

Does Seraphine counter Karma?

Yes, Seraphine has a favorable matchup against Karma with a 51.5% win rate. Seraphine has a solid advantage over Karma in lane based on current patch 26.7 data.

How do I play Seraphine against Karma?

When playing Seraphine against Karma, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.