Seraphine - League of Legends Champion
Win Rate
52.3%
Pick Rate
7.8%

Seraphinevs Karma

SSupportMage
Patch26.11
Matches776,441
LaneAll Lanes
TierAll Tiers
Last UpdatedJun 5, 2026
MethodologyData Methodology

Seraphine vs Karma is a very close matchup in LoL patch 26.11. Seraphine wins with a 50.8% win rate (+1.6%) over Karma based on 258 games. Seraphine holds the advantage in both the early and late game. Below you'll find the best Seraphine build, runes, laning stats, and strategies for the Seraphine vs Karma matchup.

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Seraphine Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Seraphine performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Seraphine - 50.8% win rate in this matchup
Seraphine
50.8% WR
VS
Karma vs Seraphine matchup - 49.2% win rate
Karma
49.2% WR

Who Wins the Seraphine vs Karma Matchup?

Seraphine wins the Seraphine vs Karma matchup
Winner
Seraphine
Matches: 258
50.8%
Win Rate
49.2%
1.5
CS / min
1.3
444
DMG / min
387
9,247
Gold / game
8,853
312
Heal / min
234
359
DMG Mitigated / min
466
1.1
CC / min
0.9
50.5%
Early Game WR
49.5%
51.0%
Late Game WR
49.0%

Seraphine vs Karma Matchup Summary

The Seraphine vs Karma matchup is a very close matchup in League of Legends ranked play. Based on 258 recent matches analyzed, Seraphine wins with a 50.8% win rate compared to Karma's 49.2%, giving Seraphine a 1.6 percentage point advantage. Seraphine holds a slight edge in both the early and late game, but the margins are thin enough that individual skill and jungle attention will often determine the outcome. Karma can still find windows through outplays and team coordination. The most significant statistical gap is in crowd control, where Seraphine leads by 0.3s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Seraphine has a statistical edge, but the margin is close enough that respecting Karma's strengths is important. Trade when cooldowns are favorable, track the enemy jungler, and build toward your strongest item spikes to convert the slight advantage into a decisive lead. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Seraphine vs Karma Laning Phase Breakdown

Seraphine wins the laning phase against Karma in League of Legends

Seraphine is favored during the laning phase against Karma, winning 4 out of 5 key stat categories. Seraphine holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.

Farming
1.5Seraphine
1.3Karma
Seraphine and Karma farm at nearly identical rates in this matchup, with only a 0.1 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
444Seraphine
387Karma
Seraphine deals 57 more champion damage per minute than Karma. While noticeable in extended trades, this gap can be offset by Karma choosing favorable fight windows, such as engaging when Seraphine's key abilities are on cooldown or trading immediately after dodging a skillshot.
Economy
9,247Seraphine
8,853Karma
Seraphine earns 394 more gold per game than Karma, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Seraphine slightly faster item completions.
Utility
1.1Seraphine
0.9Karma
Both Seraphine and Karma provide similar amounts of crowd control (0.3s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
671Seraphine
700Karma
Seraphine and Karma have comparable sustain profiles, with only 29 HP/min separating their healing and damage mitigation. Neither champion can out-attrition the other in lane, so trades will be decided by burst potential and ability usage rather than sustain.

Best Seraphine Build Against Karma

Ionian Boots of Lucidity is the optimal boots choice against Karma, providing the mobility and stats Seraphine needs most in this matchup. The top-performing core items for Seraphine against Karma are Imperial Mandate, Rylai's Crystal Scepter and Shurelya's Battlesong. This combination gives Seraphine an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 3 games — well above average and making it the top item path against Karma. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Seraphine vs Karma matchup.

Early Game vs Late Game

Early Game
Seraphine
50.5%
+1.0% advantage
Seraphine early game win rateSeraphine50.5%
Karma early game win rateKarma49.5%
Late Game
Seraphine
51.0%
+1.9% advantage
Seraphine late game win rateSeraphine51.0%
Karma late game win rateKarma49.0%

The early game (first 15 minutes) is a toss-up between Seraphine and Karma, with Seraphine holding a razor-thin 50.5% win rate edge (+1.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.

Late game (25+ minutes) is equally balanced, with Seraphine at 51.0% win rate — only 1.9 points ahead of Karma. Team fight execution and macro play determine the winner at this stage, not champion matchup advantage.

This matchup is remarkably even at every stage of the game. Neither Seraphine nor Karma has a phase-specific advantage, making this a pure skill matchup where individual mechanics, decision-making, and team coordination determine the outcome.

Best Seraphine Runes Against Karma

Sorcery rune tree - Seraphine primary runes vs KarmaSorcery
Summon Aery - best Seraphine rune vs KarmaManaflow Band - best Seraphine rune vs KarmaTranscendence - best Seraphine rune vs KarmaGathering Storm - best Seraphine rune vs Karma
Resolve rune tree - Seraphine secondary runes vs KarmaResolve
Font of Life - best Seraphine rune vs KarmaRevitalize - best Seraphine rune vs Karma
52.6% WR

The Sorcery primary with Resolve secondary combination helps Seraphine maximize their potential in this closely contested matchup, providing the right mix of offensive and defensive tools to edge out Karma.


Seraphine matchup data for League of Legends patch 26.11. The table below shows Seraphine's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Seraphine build, runes, laning stats, and early vs late game analysis for that specific matchup.

Seraphine matchup win rates and stats in League of Legends patch 26.11
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
47.75%7791.74669,35944.9%49.5%
50.91%5501.44939,17358.0%45.0%
49.45%5481.44879,00751.2%48.0%
50.83%5431.44879,19746.8%53.9%
52.69%5011.54979,35248.8%55.5%
50.21%4781.85269,25551.6%49.0%
48.69%4211.54709,01249.2%48.3%
50.00%3341.44539,01050.4%49.7%
50.91%3301.95249,71553.4%49.2%
51.72%3191.44699,56046.7%55.4%
52.44%3071.44938,93052.7%52.2%
53.17%2841.74839,53147.7%56.6%
52.84%2821.44878,90149.2%55.8%
50.78%2581.54449,24750.5%51.0%
47.97%2461.54669,32744.7%50.4%
54.85%2371.85849,76454.8%54.9%
54.85%2371.44528,96551.9%57.4%
53.07%2281.53918,66358.8%46.8%
54.63%2271.84989,66455.6%54.0%
43.13%2111.35028,90135.6%48.8%
52.22%2031.45229,03758.4%47.4%
43.22%1991.54988,96147.1%40.4%
48.44%1921.44979,41851.2%46.3%
53.45%1741.84629,23249.4%56.7%
49.70%1691.66149,70344.4%52.2%
52.26%1551.44799,11856.9%48.2%
57.53%1461.45699,69067.9%51.1%
54.48%1454.566211,52162.3%50.0%
52.52%1391.44899,05164.1%42.7%
61.29%1241.64819,07567.7%54.8%
50.00%1221.44628,51250.8%49.1%
50.00%1201.45089,23252.8%47.8%
51.30%1151.44638,90542.2%57.1%
59.13%1156.281412,23054.7%62.9%
53.49%861.54809,03567.5%41.3%
54.88%825.867711,89860.0%51.9%
61.25%804.878912,00275.9%52.9%
56.76%746.880712,47863.9%50.0%
53.42%732.05109,99152.0%54.2%
56.16%731.55149,44956.8%55.6%
46.88%641.54679,51052.0%43.6%
43.33%601.65579,12160.7%28.1%
48.33%602.14408,59548.3%48.4%
54.24%596.283112,84042.1%60.0%
54.24%593.359210,05860.9%50.0%
60.34%585.375111,90651.9%67.7%
63.16%572.056710,73279.0%55.3%
44.23%521.75759,42052.0%37.0%
51.06%472.04629,10847.6%53.9%
50.00%402.260810,02652.6%47.6%
56.76%376.389112,39562.5%52.4%
44.44%362.55159,08730.8%52.2%
60.61%334.259811,53455.6%62.5%
51.52%335.366611,60061.5%45.0%
42.42%336.281310,73542.1%42.9%
51.52%336.878711,42658.8%43.8%
65.63%321.64749,16373.3%58.8%
65.63%324.168110,15666.7%64.7%
58.06%311.64859,79966.7%52.6%
56.67%306.673310,93362.5%50.0%
41.38%291.45019,36630.8%50.0%
44.44%275.167710,72263.6%31.3%
62.96%271.649810,32862.5%63.2%
54.17%244.26249,65645.5%61.5%
50.00%222.45679,74940.0%58.3%
45.45%223.04909,41825.0%57.1%
63.64%222.250811,56760.0%64.7%
40.00%206.580113,55633.3%41.2%
55.00%206.779212,47966.7%45.5%
55.00%202.04629,45857.1%53.9%
45.00%205.871411,07240.0%50.0%
70.00%201.464510,69887.5%58.3%
63.16%191.443410,16060.0%64.3%
61.11%185.67038,05964.3%50.0%
58.82%176.286512,02650.0%63.6%
35.29%171.244610,23775.0%23.1%
75.00%166.791813,62771.4%77.8%
37.50%161.54798,92840.0%36.4%
60.00%156.776112,98866.7%55.6%
40.00%155.359710,54633.3%44.4%
60.00%151.646310,50775.0%54.5%
50.00%143.264710,32850.0%50.0%
50.00%142.65519,74250.0%50.0%
42.86%144.85849,77450.0%37.5%
53.85%136.392112,20066.7%42.9%
30.77%134.16039,87733.3%28.6%
61.54%133.15949,46842.9%83.3%
58.33%126.78259,19670.0%0.0%
50.00%124.36669,42433.3%66.7%
58.33%126.076411,19160.0%57.1%
72.73%116.175811,907100.0%66.7%
27.27%114.55499,3630.0%50.0%
54.55%116.266011,06050.0%60.0%
60.00%105.680311,24250.0%75.0%
80.00%101.44777,16187.5%50.0%
66.67%94.552110,244100.0%62.5%
44.44%91.84238,69366.7%33.3%
37.50%86.293011,95740.0%33.3%
62.50%81.66239,74233.3%80.0%
37.50%81.53958,01025.0%50.0%
37.50%81.34679,59625.0%50.0%
25.00%85.367010,06850.0%16.7%
25.00%83.45779,67325.0%25.0%
62.50%81.457011,7740.0%71.4%
75.00%85.470711,28850.0%83.3%
50.00%81.14638,69050.0%50.0%
50.00%86.298713,25366.7%40.0%
75.00%81.648710,73550.0%83.3%
85.71%71.45378,417100.0%0.0%
42.86%71.949210,03133.3%50.0%
71.43%73.163510,657100.0%60.0%
57.14%73.473912,184100.0%50.0%
100.00%73.15957,466100.0%100.0%
71.43%73.05208,01175.0%66.7%
33.33%67.382210,97625.0%50.0%
100.00%62.35489,903100.0%100.0%
83.33%62.247410,918100.0%80.0%
50.00%61.63829,86350.0%50.0%
100.00%55.957011,5490.0%100.0%
40.00%51.649610,44750.0%33.3%
60.00%51.256510,3000.0%75.0%
40.00%56.06469,77425.0%100.0%
40.00%53.864610,54966.7%0.0%
80.00%51.549910,15550.0%100.0%

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Seraphine vs Karma - Frequently Asked Questions

How does Seraphine do against Karma in League of Legends?

Seraphine wins the Seraphine vs Karma matchup with a 50.8% win rate compared to Karma's 49.2%, a 1.6 percentage point difference. This data is based on 258 recent ranked games in patch 26.11.

How does Seraphine do against Karma in the early game?

In the early game, Seraphine has the advantage against Karma with a 50.5% win rate versus 49.5%. Seraphine players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Seraphine do against Karma in the late game?

In the late game, Seraphine takes over the Seraphine vs Karma matchup with a 51.0% win rate compared to 49.0%. Seraphine scales better into team fights and objective contests after 25 minutes.

Who wins the Seraphine vs Karma matchup?

Seraphine wins the matchup against Karma with a 50.8% win rate in League of Legends patch 26.11. The 1.6 percentage point advantage means Seraphine is slightly favored in this lane matchup based on 258 games analyzed.

What is the best Seraphine build against Karma?

The best Seraphine build against Karma includes Imperial Mandate, Rylai's Crystal Scepter, Shurelya's Battlesong with Ionian Boots of Lucidity. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Seraphine runes against Karma?

The best Seraphine runes against Karma use the Sorcery primary tree with Resolve secondary. This rune setup achieves a 52.6% win rate in the Seraphine vs Karma matchup. See the full rune breakdown in the matchup comparison above.

Does Seraphine counter Karma?

Yes, Seraphine has a favorable matchup against Karma with a 50.8% win rate. Seraphine slightly edges out Karma in lane based on current patch 26.11 data.

How do I play Seraphine against Karma?

When playing Seraphine against Karma, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.