Karthus - League of Legends Champion
Win Rate
47.2%
Pick Rate
1.0%

Karthusvs Orianna

FMage
Patch26.5
Matches469,660
LaneAll Lanes
TierAll Tiers
Last UpdatedMar 12, 2026
MethodologyData Methodology

Karthus vs Orianna is a decisive matchup in LoL patch 26.5. Orianna wins with a 60.0% win rate (+20.0%) over Karthus based on 5 games. Orianna wins the early laning phase while Karthus scales better into the late game. Below you'll find the best Karthus build, runes, laning stats, and strategies for the Karthus vs Orianna matchup.

Karthus Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Karthus performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Orianna - 40.0% win rateOrianna(40.0%)
Karthus - 40.0% win rate in this matchup
Karthus
40.0% WR
VS
Orianna vs Karthus matchup - 60.0% win rate
Orianna
60.0% WR

Who Wins the Karthus vs Orianna Matchup?

Orianna wins the Karthus vs Orianna matchup
Winner
Orianna
Matches: 5
40.0%
Win Rate
60.0%
6.4
CS / min
7.2
1,033
DMG / min
1,279
12,247
Gold / game
15,572
128
Heal / min
129
522
DMG Mitigated / min
628
0.6
CC / min
0.9
0.0%
Early Game WR
100.0%
50.0%
Late Game WR
50.0%

Karthus vs Orianna Matchup Summary

The Karthus vs Orianna matchup is a decisive matchup in League of Legends ranked play. Based on 5 recent matches analyzed, Orianna wins with a 60.0% win rate compared to Karthus's 40.0%, giving Orianna a 20.0 percentage point advantage. Game phase dynamics play a critical role here: Orianna controls the early laning stage, but Karthus outscales as the game goes longer. The matchup shifts dramatically depending on game length — Orianna needs to press advantages before Karthus reaches their power spikes, while Karthus should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Orianna leads by 0.3s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Orianna has a strong advantage in this matchup. Karthus players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Orianna overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Karthus vs Orianna Laning Phase Breakdown

Orianna wins the laning phase against Karthus in League of Legends

Orianna is favored during the laning phase against Karthus, winning 5 out of 5 key stat categories. Orianna holds advantages in farming, damage, gold income, crowd control and sustain, making them the stronger laner in this matchup.

Farming
6.4Karthus
7.2Orianna
Orianna edges out Karthus by 0.7 CS per minute — a moderate farming advantage that adds up to roughly 11 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Orianna.
Damage
1,033Karthus
1,279Orianna
Orianna heavily out-damages Karthus by 246 DMG/min, dominating both short trades and all-in fights. Karthus should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Orianna's sustained damage advantage take over.
Economy
12,247Karthus
15,572Orianna
Orianna generates a commanding 3,325 more gold per game than Karthus. This substantial economic advantage means Orianna consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Karthus should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.6Karthus
0.9Orianna
Orianna provides 0.3 seconds more crowd control per minute than Karthus, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Orianna coordinate with their jungler and control the pace of skirmishes.
Sustain
650Karthus
757Orianna
Orianna heals and mitigates 106 more damage per minute than Karthus, providing moderate extra durability. This sustain edge allows Orianna to stay in lane longer between recalls and gradually win extended wars of attrition. Consider building early grievous wounds if playing Karthus.

Best Karthus Build Against Orianna

Spellslinger's Shoes is the optimal boots choice against Orianna, providing the mobility and stats Karthus needs most in this matchup. The top-performing core items for Karthus against Orianna are Rod of Ages, Liandry's Torment and Void Staff. This combination gives Karthus an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Orianna. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Karthus vs Orianna matchup.

Early Game vs Late Game

Early Game
Orianna
100.0%
+100.0% advantage
Karthus early game win rateKarthus0.0%
Orianna early game win rateOrianna100.0%
Late Game
Karthus
50.0%
+0.0% advantage
Karthus late game win rateKarthus50.0%
Orianna late game win rateOrianna50.0%

Orianna dominates the early game (first 15 minutes) with a commanding 100.0% win rate — a 100.0 percentage point lead over Karthus. This lopsided early game means Orianna can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Late game (25+ minutes) is equally balanced, with Karthus at 50.0% win rate — only 0.0 points ahead of Orianna. Team fight execution and macro play determine the winner at this stage, not champion matchup advantage.

The power dynamics shift as the game progresses — Orianna has the edge early, but Karthus gradually takes over. However, the margins are slim enough that either champion can win at any stage with the right plays. Focus on taking advantages when you have them rather than waiting for a specific game phase.

Best Karthus Runes Against Orianna

Domination rune tree - Karthus primary runes vs OriannaDomination
Dark Harvest - best Karthus rune vs OriannaTaste of Blood - best Karthus rune vs OriannaGrisly Mementos - best Karthus rune vs OriannaUltimate Hunter - best Karthus rune vs Orianna
Precision rune tree - Karthus secondary runes vs OriannaPrecision
Presence of Mind - best Karthus rune vs OriannaLast Stand - best Karthus rune vs Orianna
100.0% WR

The Domination and Precision rune setup gives Karthus the best tools to compete against Orianna in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Karthus matchup data for League of Legends patch 26.5. The table below shows Karthus's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Karthus build, runes, laning stats, and early vs late game analysis for that specific matchup.

Karthus matchup win rates and stats in League of Legends patch 26.5
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
50.00%341.21,17213,92553.3%47.4%
50.00%261.41,14713,32457.1%41.7%
56.00%251.61,29617,07050.0%57.1%
39.13%231.41,05513,96370.0%15.4%
43.48%231.51,27715,37342.9%43.8%
38.10%211.594111,08146.1%25.0%
52.38%211.51,40417,6860.0%57.9%
21.05%191.81,33614,18425.0%18.2%
72.22%181.81,28817,43080.0%69.2%
33.33%186.51,10512,13242.9%27.3%
66.67%181.71,24314,43071.4%63.6%
41.18%171.61,11512,58933.3%50.0%
23.53%171.31,07314,52150.0%15.4%
37.50%161.81,41114,48025.0%41.7%
37.50%166.01,41016,26950.0%35.7%
33.33%151.01,24414,35228.6%37.5%
33.33%151.51,03412,86650.0%22.2%
53.33%151.21,19315,04333.3%66.7%
57.14%141.890212,46750.0%66.7%
28.57%141.51,24314,76925.0%30.0%
46.15%136.51,19015,20560.0%37.5%
53.85%132.01,11213,09642.9%66.7%
50.00%121.21,07011,80850.0%50.0%
63.64%121.61,08812,39880.0%50.0%
50.00%126.31,32315,50833.3%55.6%
9.09%111.31,25114,28325.0%0.0%
36.36%112.01,08812,66633.3%40.0%
54.55%116.81,20012,46240.0%66.7%
50.00%105.81,22913,97433.3%57.1%
40.00%101.21,02415,09025.0%50.0%
60.00%101.71,09315,28550.0%62.5%
30.00%101.51,24216,3770.0%37.5%
50.00%105.81,46315,926100.0%37.5%
50.00%105.097313,15725.0%66.7%
55.56%94.31,24613,49040.0%75.0%
66.67%91.51,27716,44133.3%83.3%
33.33%93.11,31915,1300.0%50.0%
44.44%94.11,20214,68950.0%42.9%
66.67%91.41,04312,092100.0%40.0%
55.56%96.31,09414,259100.0%42.9%
75.00%86.31,42417,45266.7%80.0%
62.50%86.51,31815,12766.7%60.0%
50.00%82.082712,73742.9%100.0%
12.50%81.498812,7150.0%25.0%
37.50%81.31,23015,8990.0%42.9%
37.50%86.51,13312,33040.0%33.3%
50.00%81.61,58817,22650.0%50.0%
37.50%83.71,41015,914100.0%28.6%
37.50%81.491411,72940.0%33.3%
57.14%72.992411,97175.0%33.3%
42.86%73.31,17612,85050.0%40.0%
42.86%75.11,23614,48025.0%66.7%
33.33%63.11,15811,03825.0%50.0%
66.67%64.71,16213,68466.7%66.7%
33.33%61.490210,54620.0%100.0%
33.33%65.41,44514,90633.3%33.3%
33.33%66.298411,40950.0%25.0%
16.67%61.21,06213,8050.0%25.0%
40.00%56.21,48317,9290.0%40.0%
60.00%55.51,04312,857100.0%50.0%
60.00%55.91,41216,170100.0%50.0%
40.00%51.91,40515,5740.0%66.7%
60.00%52.491212,68833.3%100.0%
80.00%57.41,36011,32466.7%100.0%
40.00%56.89229,67433.3%50.0%
40.00%56.81,70117,73450.0%33.3%
40.00%56.41,03312,2470.0%50.0%
80.00%51.21,14412,971100.0%50.0%
60.00%51.492713,30050.0%66.7%
40.00%56.61,57718,837100.0%0.0%
60.00%56.31,31513,61150.0%100.0%
40.00%51.71,16416,20950.0%33.3%

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Karthus vs Orianna - Frequently Asked Questions

How does Karthus do against Orianna in League of Legends?

Orianna wins the Karthus vs Orianna matchup with a 60.0% win rate compared to Karthus's 40.0%, a 20.0 percentage point difference. This data is based on 5 recent ranked games in patch 26.5.

How does Karthus do against Orianna in the early game?

In the early game, Orianna has the advantage against Karthus with a 100.0% win rate versus 0.0%. Orianna players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Karthus do against Orianna in the late game?

In the late game, Karthus takes over the Karthus vs Orianna matchup with a 50.0% win rate compared to 50.0%. Karthus scales better into team fights and objective contests after 25 minutes.

Who wins the Karthus vs Orianna matchup?

Orianna wins the matchup against Karthus with a 60.0% win rate in League of Legends patch 26.5. The 20.0 percentage point advantage means Orianna is significantly favored in this lane matchup based on 5 games analyzed.

What is the best Karthus build against Orianna?

The best Karthus build against Orianna includes Rod of Ages, Liandry's Torment, Void Staff with Spellslinger's Shoes. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Karthus runes against Orianna?

The best Karthus runes against Orianna use the Domination primary tree with Precision secondary. This rune setup achieves a 100.0% win rate in the Karthus vs Orianna matchup. See the full rune breakdown in the matchup comparison above.

Does Karthus counter Orianna?

No, Karthus struggles against Orianna with only a 40.0% win rate. Orianna has the advantage in this matchup. Karthus players should focus on safe farming and avoiding extended trades to minimize Orianna's lead.

How do I play Karthus against Orianna?

When playing Karthus against Orianna, play cautiously and avoid Orianna's power spikes. Focus on safe farming — you outscale Orianna in the late game. Use the matchup-specific build and runes above to optimize your chances.