Karthus - League of Legends Champion
Win Rate
50.5%
Pick Rate
1.4%

Karthusvs Qiyana

BMage
Patch26.9
Matches514,344
LaneAll Lanes
TierAll Tiers
Last UpdatedMay 9, 2026
MethodologyData Methodology

Karthus vs Qiyana is a decisive matchup in LoL patch 26.9. Karthus wins with a 80.0% win rate (+60.0%) over Qiyana based on 5 games. Karthus wins the early laning phase while Qiyana scales better into the late game. Below you'll find the best Karthus build, runes, laning stats, and strategies for the Karthus vs Qiyana matchup.

Karthus Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Karthus performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Qiyana - 80.0% win rateQiyana(80.0%)
Karthus - 80.0% win rate in this matchup
Karthus
80.0% WR
VS
Qiyana vs Karthus matchup - 20.0% win rate
Qiyana
20.0% WR

Who Wins the Karthus vs Qiyana Matchup?

Karthus wins the Karthus vs Qiyana matchup
Winner
Karthus
Matches: 5
80.0%
Win Rate
20.0%
2.9
CS / min
2.2
1,246
DMG / min
880
14,608
Gold / game
11,986
268
Heal / min
242
451
DMG Mitigated / min
563
0.5
CC / min
0.8
100.0%
Early Game WR
0.0%
0.0%
Late Game WR
100.0%

Karthus vs Qiyana Matchup Summary

The Karthus vs Qiyana matchup is a decisive matchup in League of Legends ranked play. Based on 5 recent matches analyzed, Karthus wins with a 80.0% win rate compared to Qiyana's 20.0%, giving Karthus a 60.0 percentage point advantage. Game phase dynamics play a critical role here: Karthus controls the early laning stage, but Qiyana outscales as the game goes longer. The matchup shifts dramatically depending on game length — Karthus needs to press advantages before Qiyana reaches their power spikes, while Qiyana should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Qiyana leads by 0.3s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Karthus players can confidently pick into Qiyana and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Qiyana away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Karthus vs Qiyana Laning Phase Breakdown

Karthus wins the laning phase against Qiyana in League of Legends

Karthus is favored during the laning phase against Qiyana, winning 3 out of 5 key stat categories. Karthus holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.

Farming
2.9Karthus
2.2Qiyana
Karthus edges out Qiyana by 0.7 CS per minute — a moderate farming advantage that adds up to roughly 11 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Karthus.
Damage
1,246Karthus
880Qiyana
Karthus heavily out-damages Qiyana by 366 DMG/min, dominating both short trades and all-in fights. Qiyana should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Karthus's sustained damage advantage take over.
Economy
14,608Karthus
11,986Qiyana
Karthus generates a commanding 2,622 more gold per game than Qiyana. This substantial economic advantage means Karthus consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Qiyana should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.5Karthus
0.8Qiyana
Qiyana provides 0.3 seconds more crowd control per minute than Karthus, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Qiyana coordinate with their jungler and control the pace of skirmishes.
Sustain
719Karthus
805Qiyana
Qiyana heals and mitigates 86 more damage per minute than Karthus, providing moderate extra durability. This sustain edge allows Qiyana to stay in lane longer between recalls and gradually win extended wars of attrition. Consider building early grievous wounds if playing Karthus.

Best Karthus Build Against Qiyana

Sorcerer's Shoes is the optimal boots choice against Qiyana, providing the mobility and stats Karthus needs most in this matchup. The top-performing core items for Karthus against Qiyana are Shadowflame, Void Staff and Rabadon's Deathcap. This combination gives Karthus an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Qiyana. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Karthus vs Qiyana matchup.

Early Game vs Late Game

Early Game
Karthus
100.0%
+100.0% advantage
Karthus early game win rateKarthus100.0%
Qiyana early game win rateQiyana0.0%
Late Game
Qiyana
100.0%
+100.0% advantage
Karthus late game win rateKarthus0.0%
Qiyana late game win rateQiyana100.0%

Karthus dominates the early game (first 15 minutes) with a commanding 100.0% win rate — a 100.0 percentage point lead over Qiyana. This lopsided early game means Karthus can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Qiyana is far superior in the late game (25+ minutes), boasting a 100.0% win rate — 100.0 points above Karthus. Extended games heavily favor Qiyana, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Karthus must aggressively press their early advantage and close out the game before Qiyana reaches their scaling breakpoints. If Qiyana survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Karthus Runes Against Qiyana

Sorcery rune tree - Karthus primary runes vs QiyanaSorcery
Deathfire Touch - best Karthus rune vs QiyanaAxiom Arcanist - best Karthus rune vs QiyanaAbsolute Focus - best Karthus rune vs QiyanaGathering Storm - best Karthus rune vs Qiyana
Domination rune tree - Karthus secondary runes vs QiyanaDomination
Cheap Shot - best Karthus rune vs QiyanaUltimate Hunter - best Karthus rune vs Qiyana
100.0% WR

Running Sorcery primary with Domination secondary allows Karthus to press their advantage against Qiyana, amplifying the strengths that make this a favorable matchup.


Karthus matchup data for League of Legends patch 26.9. The table below shows Karthus's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Karthus build, runes, laning stats, and early vs late game analysis for that specific matchup.

Karthus matchup win rates and stats in League of Legends patch 26.9
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
60.47%431.51,21114,74546.7%67.9%
59.52%421.41,14614,12047.6%71.4%
43.59%391.31,14213,12747.1%40.9%
63.89%366.61,28514,80341.7%75.0%
45.45%331.51,23015,24561.5%35.0%
61.29%311.61,18415,08750.0%66.7%
35.48%311.41,30212,72033.3%37.5%
40.00%301.91,23113,75450.0%33.3%
58.62%291.31,15214,88977.8%50.0%
55.17%297.01,46114,73946.1%62.5%
55.17%296.81,36014,77653.9%56.3%
64.29%286.81,50015,24670.0%61.1%
57.69%261.41,39516,57285.7%47.4%
48.00%251.31,25314,19450.0%47.1%
44.00%256.71,35112,58366.7%23.1%
52.00%257.11,23013,93158.3%46.1%
29.17%241.61,30715,28516.7%33.3%
68.18%226.21,39316,20160.0%75.0%
52.38%212.499313,08937.5%61.5%
38.10%211.61,03913,12540.0%36.4%
66.67%217.31,39113,87180.0%54.5%
70.00%201.41,19014,75962.5%75.0%
42.11%192.61,06712,40655.6%30.0%
36.84%196.21,23012,04245.5%25.0%
73.68%195.21,13412,16276.9%66.7%
50.00%182.21,19412,68225.0%70.0%
41.18%171.61,23013,52933.3%45.5%
41.18%172.51,18814,84260.0%33.3%
47.06%171.91,26214,04650.0%45.5%
50.00%161.41,35715,18757.1%44.4%
62.50%166.51,38415,94771.4%55.6%
50.00%161.61,04112,14580.0%36.4%
60.00%151.61,37813,28057.1%62.5%
60.00%152.01,30416,40150.0%63.6%
60.00%151.21,15514,70750.0%66.7%
64.29%141.51,28914,83560.0%66.7%
35.71%141.51,16811,78937.5%33.3%
46.15%131.21,21513,64050.0%42.9%
23.08%132.71,10713,7260.0%30.0%
41.67%121.91,13413,65120.0%57.1%
41.67%121.31,43215,34240.0%42.9%
50.00%121.61,37216,603100.0%33.3%
45.45%113.41,00014,20233.3%50.0%
70.00%107.41,30813,51985.7%33.3%
70.00%106.31,14413,81975.0%66.7%
50.00%101.51,09414,69540.0%60.0%
66.67%95.31,27511,16780.0%50.0%
77.78%96.91,54314,94183.3%66.7%
77.78%96.41,42617,292100.0%75.0%
55.56%92.01,05513,61450.0%60.0%
55.56%96.71,32010,34750.0%60.0%
55.56%97.01,42015,8710.0%83.3%
87.50%86.01,20913,52866.7%100.0%
62.50%81.591411,68960.0%66.7%
75.00%83.31,18115,18766.7%80.0%
37.50%81.61,32512,29233.3%50.0%
25.00%81.01,1779,88240.0%0.0%
37.50%85.91,29413,4380.0%42.9%
87.50%81.193011,739100.0%66.7%
37.50%85.196910,8330.0%75.0%
50.00%84.71,24715,16125.0%75.0%
37.50%82.11,24813,00025.0%50.0%
12.50%84.596911,57216.7%0.0%
75.00%81.41,01211,30975.0%75.0%
37.50%83.41,28413,665100.0%16.7%
42.86%74.81,05911,2810.0%75.0%
71.43%77.31,47814,622100.0%66.7%
42.86%72.61,21313,76540.0%50.0%
85.71%71.31,06312,33480.0%100.0%
71.43%71.71,2489,768100.0%50.0%
85.71%76.81,1058,88485.7%0.0%
85.71%71.31,63616,296100.0%83.3%
42.86%76.61,34314,33650.0%33.3%
57.14%77.61,4799,02660.0%50.0%
42.86%76.11,30214,16475.0%0.0%
33.33%62.81,36614,33150.0%25.0%
16.67%67.31,71116,7850.0%20.0%
66.67%66.71,18712,81350.0%75.0%
83.33%62.71,18713,78266.7%100.0%
33.33%67.31,22311,6740.0%66.7%
33.33%67.01,50812,64533.3%33.3%
0.00%57.11,77818,0110.0%0.0%
40.00%56.71,0339,56725.0%100.0%
60.00%52.09609,78750.0%100.0%
20.00%56.31,37615,1170.0%33.3%
80.00%52.91,24614,608100.0%0.0%
80.00%51.31,27114,68650.0%100.0%
40.00%51.31,06613,764100.0%25.0%
80.00%57.41,06214,08175.0%100.0%

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Karthus vs Qiyana - Frequently Asked Questions

How does Karthus do against Qiyana in League of Legends?

Karthus wins the Karthus vs Qiyana matchup with a 80.0% win rate compared to Qiyana's 20.0%, a 60.0 percentage point difference. This data is based on 5 recent ranked games in patch 26.9.

How does Karthus do against Qiyana in the early game?

In the early game, Karthus has the advantage against Qiyana with a 100.0% win rate versus 0.0%. Karthus players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Karthus do against Qiyana in the late game?

In the late game, Qiyana takes over the Karthus vs Qiyana matchup with a 100.0% win rate compared to 0.0%. Qiyana scales better into team fights and objective contests after 25 minutes.

Who wins the Karthus vs Qiyana matchup?

Karthus wins the matchup against Qiyana with a 80.0% win rate in League of Legends patch 26.9. The 60.0 percentage point advantage means Karthus is significantly favored in this lane matchup based on 5 games analyzed.

What is the best Karthus build against Qiyana?

The best Karthus build against Qiyana includes Shadowflame, Void Staff, Rabadon's Deathcap with Sorcerer's Shoes. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Karthus runes against Qiyana?

The best Karthus runes against Qiyana use the Sorcery primary tree with Domination secondary. This rune setup achieves a 100.0% win rate in the Karthus vs Qiyana matchup. See the full rune breakdown in the matchup comparison above.

Does Karthus counter Qiyana?

Yes, Karthus has a favorable matchup against Qiyana with a 80.0% win rate. Karthus strongly counters Qiyana in lane based on current patch 26.9 data.

How do I play Karthus against Qiyana?

When playing Karthus against Qiyana, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.