
- Win Rate
- 48.5%
- Pick Rate
- 2.6%
- Ban Rate
- 3.0%
Milio vs Seraphine
- Patch
- 26.22
- Games
- 5,024
- Lane
- All Lanes
- Tier
- All Tiers
- Last Updated
- Nov 14, 2026 UTC
- Author
- Dakota Chinnick
- Methodology
- Data Methodology
Milio vs Seraphine (Support): Milio wins 52.2% of 638 ranked games over the last 2 patches (gold diff at 15: -352). Patch 26.22 build & runes.
Milio vs Seraphine is close over 638 games: Milio wins 52.2%, and the 95% range (48.3–56.0%) includes 50%, so Milio is only marginally ahead.
Milio Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Milio performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.


Who wins Milio vs Seraphine?
Milio wins 52.2% of these games. With this many games the true rate is most likely between 48.3% and 56.0% (95% range).
- Expected
- 47.9% From both champions' overall Support win rates
- Matchup effect
- +4.3 pts Observed minus expected
- Sample
- 638 games Lane: Support · Patch 26.21–26.22
- vs patch 26.21
- −2.0 pts Within normal patch-to-patch noise
Lane: Support · Ranked Solo/Duo & Flex · North America server · All ranks · Patch 26.21–26.22 · Oct 27 – Nov 14
The headline win rate covers patches 26.21–26.22 (638 games). The lane, game-length, build and rune sections below use patch 26.22 only (282 games).
Key takeaways
- Milio vs Seraphine is close over 638 games: Milio wins 52.2%, and the 95% range (48.3–56.0%) includes 50%, so Milio is only marginally ahead.
- That is 4.3 points better for Milio than both champions' overall Support win rates predict (47.9%), so the matchup itself favors this pick — not just champion strength.
- Seraphine usually wins the lane: 352 gold ahead of Milio at 15 minutes on average (279 games with a 15-minute snapshot).
- Milio players pick Health (defense) much less often against Seraphine: 17.0% of their other Support games, 9.6% here.
How we calculate this
Games: ranked Solo/Duo and Flex games on the North America server from the patch shown. Remakes (games under 5 minutes) are excluded.
A game only counts when Milio and Seraphine played the same position on opposite teams, so roaming, lane swaps within a team or a champion merely being in the same game never count as this matchup.
The 95% range is a Wilson score interval. Confidence comes from how wide that range is: within ±3 points is very high, ±5 high, ±8 moderate, anything wider low. Below 20 games a matchup is not classified at all.
Expected win rate combines both champions’ win rates in this lane (same games and filters) with the log5 formula: E = A(1−B) / (A(1−B) + B(1−A)). Matchup effect = observed − expected.
"What changes" compares Milio's choices in this matchup with the same champion's other games in the same lane, and lists a change only when it is at least 3 points and statistically significant (two-proportion z-test, |z| ≥ 2, 20+ games).
Results are not split by rank: the sample per rank is too small for honest per-rank matchup numbers.
Milio vs Seraphine Laning Stats
At 15 minutes
Whole-game averages
Milio vs Seraphine Win Rate by Game Length
Milio's win rate against Seraphine by game length. The dot is the win rate, the bar its 95% range and the dashed line the champion's usual win rate at that length. Lengths with fewer than 25 games are left blank.
No game length stands out: Milio's results against Seraphine in short and long games are within the margin of error of each other.
Milio vs Seraphine Power Spikes
Who is ahead at each stage, measured from these games. A stage reads "Even" when the difference is inside the margin of error, and "Insufficient data" when there are too few games to tell.
- Lane (15 min)SeraphineMilio gold at 15: −352
- First itemEvenMilio: 12.9 min · Seraphine: 13.0 min
- Games under 20 minInsufficient data
- 20–30 min gamesEvenMilio wins 47.2% of 123 games
- 30+ min gamesEvenMilio wins 55.0% of 131 games
What Milio Changes Against Seraphine
Choices Milio players make noticeably more or less often in this matchup than in their other Support games.
Health (defense)Stat shardUsually17.0%vs Seraphine9.6%−7.4 pts40.7% WR here
Usually10.2%vs Seraphine17.0%+6.9 pts56.3% WR here
Health Scaling (defense)Stat shardUsually80.9%vs Seraphine86.5%+5.6 pts52.0% WR here
Best Milio Build vs Seraphine
Usual Milio build (Support)
78.6% win rate · 28 games
Against Seraphine
Not enough matchup-specific build data: only 16 of 98 Milio games against Seraphine carried a complete build, which is too few to recommend an item path from. Use Milio's standard build instead.
- Milio usually completes Echoes of Helia first, at 12.9 min (median of 116 games).
- Seraphine usually completes Echoes of Helia first, at 13.0 min (median of 150 games).
- Skill priority: E > W > Q — the same as usual.
Builds are ranked by the lower edge of their win rate range, not the raw win rate, so a build seen in a handful of wins never outranks a proven one.
Best Milio Runes vs Seraphine
Plan your Milio draft in Draft Lab
Draft Lab lays out both teams lane by lane with live matchup win rates, damage profiles and game-phase lean, and suggests picks and bans from current meta data.
- Full 5v5 draft board
- Lane matchup win rates
- Pick and ban suggestions

Milio matchup data for League of Legends patch 26.22. The table below shows Milio's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Milio build, runes, laning stats, and early vs late game analysis for that specific matchup.
Other Milio Matchups
Hardest for Milio
Easiest for Milio
Win rate and games for each matchup. Lists are ranked by the edge of the 95% range so small samples cannot top them; matchups with at least 50 games only.
Help us maintain accuracy! If you notice incorrect stats, missing data, or any issues, your feedback directly improves the quality of our data for the entire community.
Milio vs Seraphine FAQ - Patch 26.21–26.22
Who wins Milio vs Seraphine?
Milio vs Seraphine is close over 638 games: Milio wins 52.2%, and the 95% range (48.3–56.0%) includes 50%, so Milio is only marginally ahead.
What is Milio's win rate against Seraphine?
Milio wins 52.2% of 638 Support games against Seraphine on patch 26.21–26.22 (95% range 48.3–56.0%). Based on both champions' overall Support win rates, 47.9% would be expected.
Does Milio counter Seraphine?
Not clearly. Milio wins 52.2% of 638 games against Seraphine, and the 95% range (48.3–56.0%) includes 50%, so neither champion reliably counters the other on current data.
Who wins lane, Milio or Seraphine?
Seraphine usually wins the lane: 352 gold ahead of Milio at 15 minutes on average (279 games with a 15-minute snapshot).
Does Milio outscale Seraphine?
Not measurably: Milio's win rate against Seraphine in games of 25 minutes or less and in longer games is within the margin of error of each other.
When is Seraphine strongest against Milio?
Seraphine is measurably ahead in: Lane (15 min).
What should Milio build against Seraphine?
There are not enough games for a matchup-specific core, so use Milio's usual Support core: Moonstone Renewer, Redemption, Shurelya's Battlesong. The biggest change against Seraphine: Mikael's Blessing (10.2% usually, 17.0% here).
What runes should Milio use against Seraphine?
Summon Aery with Sorcery and Resolve — 54.3% over 129 games against Seraphine. The biggest change against Seraphine: Health (defense) (17.0% usually, 9.6% here).
