Milio - League of Legends Champion
Win Rate
51.8%
Pick Rate
2.8%

Miliovs Seraphine

SSupportMage
Patch26.7
Matches949,984
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 25, 2026
MethodologyData Methodology

Milio vs Seraphine is a decisive matchup in LoL patch 26.7. Milio wins with a 55.6% win rate (+11.1%) over Seraphine based on 126 games. Milio holds the advantage in both the early and late game. Below you'll find the best Milio build, runes, laning stats, and strategies for the Milio vs Seraphine matchup.

Milio Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Milio performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Seraphine - 55.6% win rateSeraphine(55.6%)
Milio - 55.6% win rate in this matchup
Milio
55.6% WR
VS
Seraphine vs Milio matchup - 44.4% win rate
Seraphine
44.4% WR

Who Wins the Milio vs Seraphine Matchup?

Milio wins the Milio vs Seraphine matchup
Winner
Milio
Matches: 126
55.6%
Win Rate
44.4%
0.9
CS / min
1.3
188
DMG / min
407
8,154
Gold / game
8,509
452
Heal / min
320
323
DMG Mitigated / min
338
0.7
CC / min
1.1
57.1%
Early Game WR
42.9%
54.0%
Late Game WR
46.0%

Milio vs Seraphine Matchup Summary

The Milio vs Seraphine matchup is a decisive matchup in League of Legends ranked play. Based on 126 recent matches analyzed, Milio wins with a 55.6% win rate compared to Seraphine's 44.4%, giving Milio a 11.1 percentage point advantage. Milio dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Seraphine players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in damage output, where Seraphine leads by 219 DMG/min — a difference that heavily influences the outcome of trades and skirmishes. Milio players can confidently pick into Seraphine and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Seraphine away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Milio vs Seraphine Laning Phase Breakdown

Seraphine wins the laning phase against Milio in League of Legends

Seraphine is favored during the laning phase against Milio, winning 4 out of 5 key stat categories. Seraphine holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.

Farming
0.9Milio
1.3Seraphine
Seraphine edges out Milio by 0.3 CS per minute — a moderate farming advantage that adds up to roughly 5 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Seraphine.
Damage
188Milio
407Seraphine
Seraphine heavily out-damages Milio by 219 DMG/min, dominating both short trades and all-in fights. Milio should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Seraphine's sustained damage advantage take over.
Economy
8,154Milio
8,509Seraphine
Seraphine earns 355 more gold per game than Milio, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Seraphine slightly faster item completions.
Utility
0.7Milio
1.1Seraphine
Seraphine provides 0.5 seconds more crowd control per minute than Milio, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Seraphine coordinate with their jungler and control the pace of skirmishes.
Sustain
776Milio
658Seraphine
Milio heals and mitigates 118 more damage per minute than Seraphine, providing moderate extra durability. This sustain edge allows Milio to stay in lane longer between recalls and gradually win extended wars of attrition. Consider building early grievous wounds if playing Seraphine.

Best Milio Build Against Seraphine

Ionian Boots of Lucidity is the optimal boots choice against Seraphine, providing the mobility and stats Milio needs most in this matchup. The top-performing core items for Milio against Seraphine are Echoes of Helia, Moonstone Renewer and Diadem of Songs. This combination gives Milio an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 75.0% win rate across 4 games — well above average and making it the top item path against Seraphine. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Milio vs Seraphine matchup.

Early Game vs Late Game

Early Game
Milio
57.1%
+14.3% advantage
Milio early game win rateMilio57.1%
Seraphine early game win rateSeraphine42.9%
Late Game
Milio
54.0%
+7.9% advantage
Milio late game win rateMilio54.0%
Seraphine late game win rateSeraphine46.0%

Milio dominates the early game (first 15 minutes) with a commanding 57.1% win rate — a 14.3 percentage point lead over Seraphine. This lopsided early game means Milio can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Milio is far superior in the late game (25+ minutes), boasting a 54.0% win rate — 7.9 points above Seraphine. Extended games heavily favor Milio, whose kit and scaling make them a dominant force in team fights and objective control.

Milio holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Seraphine players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Milio Runes Against Seraphine

Sorcery rune tree - Milio primary runes vs SeraphineSorcery
Summon Aery - best Milio rune vs SeraphineManaflow Band - best Milio rune vs SeraphineTranscendence - best Milio rune vs SeraphineScorch - best Milio rune vs Seraphine
Inspiration rune tree - Milio secondary runes vs SeraphineInspiration
Biscuit Delivery - best Milio rune vs SeraphineCosmic Insight - best Milio rune vs Seraphine
54.5% WR

Running Sorcery primary with Inspiration secondary allows Milio to press their advantage against Seraphine, amplifying the strengths that make this a favorable matchup.


Milio matchup data for League of Legends patch 26.7. The table below shows Milio's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Milio build, runes, laning stats, and early vs late game analysis for that specific matchup.

Milio matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
48.87%2210.92068,35043.4%53.9%
59.18%1470.92128,26756.9%61.3%
54.62%1300.92067,85255.4%53.6%
59.06%1270.92008,23756.4%61.1%
55.56%1260.91888,15457.1%54.0%
52.63%1141.01777,78149.2%56.6%
51.33%1130.91898,14545.6%57.1%
49.07%1080.91708,10746.7%50.8%
38.04%921.12038,10738.6%37.5%
45.88%850.92148,38850.0%42.2%
48.24%850.92018,14542.1%53.2%
58.02%810.91788,50148.6%65.9%
55.56%810.92008,26856.1%55.0%
59.49%790.91988,08558.3%60.5%
56.16%730.92138,34757.1%55.6%
56.25%641.02138,63960.0%53.9%
46.67%600.92118,67145.8%47.2%
36.21%580.92297,96039.3%33.3%
40.74%540.91487,85747.8%35.5%
50.98%510.92158,48944.0%57.7%
44.90%491.02018,07132.0%58.3%
53.06%491.01958,17840.0%66.7%
48.98%491.01997,46946.7%52.6%
51.02%490.92438,42045.8%56.0%
51.11%450.92028,66436.4%65.2%
56.82%441.02038,23731.8%81.8%
72.09%430.82648,49663.6%81.0%
44.74%380.92088,63540.0%47.8%
51.35%370.92237,84942.1%61.1%
73.53%340.92068,02982.3%64.7%
37.04%270.92027,89825.0%54.5%
56.00%250.92018,15960.0%53.3%
64.00%251.01797,35970.6%50.0%
47.83%230.82168,04669.2%20.0%
50.00%181.11868,24344.4%55.6%
46.67%150.91657,08737.5%57.1%
38.46%130.71728,43150.0%33.3%
84.62%131.22328,505100.0%60.0%
72.73%110.81758,584100.0%40.0%
72.73%110.82199,77950.0%77.8%
50.00%100.82389,84366.7%42.9%
22.22%90.82029,9860.0%25.0%
33.33%91.121810,2250.0%37.5%
55.56%91.02288,11860.0%50.0%
37.50%80.91998,6880.0%50.0%
50.00%80.81689,260100.0%33.3%
71.43%71.31668,934100.0%60.0%
14.29%70.92058,6000.0%20.0%
83.33%60.82388,66966.7%100.0%
33.33%60.91829,672100.0%20.0%
16.67%60.91817,8950.0%33.3%
50.00%60.81677,63325.0%100.0%
33.33%61.62459,48250.0%25.0%
40.00%51.21377,36533.3%50.0%
80.00%51.01967,91266.7%100.0%

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Milio vs Seraphine - Frequently Asked Questions

How does Milio do against Seraphine in League of Legends?

Milio wins the Milio vs Seraphine matchup with a 55.6% win rate compared to Seraphine's 44.4%, a 11.1 percentage point difference. This data is based on 126 recent ranked games in patch 26.7.

How does Milio do against Seraphine in the early game?

In the early game, Milio has the advantage against Seraphine with a 57.1% win rate versus 42.9%. Milio players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Milio do against Seraphine in the late game?

In the late game, Milio takes over the Milio vs Seraphine matchup with a 54.0% win rate compared to 46.0%. Milio scales better into team fights and objective contests after 25 minutes.

Who wins the Milio vs Seraphine matchup?

Milio wins the matchup against Seraphine with a 55.6% win rate in League of Legends patch 26.7. The 11.1 percentage point advantage means Milio is significantly favored in this lane matchup based on 126 games analyzed.

What is the best Milio build against Seraphine?

The best Milio build against Seraphine includes Echoes of Helia, Moonstone Renewer, Diadem of Songs with Ionian Boots of Lucidity. This build achieves a 75.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Milio runes against Seraphine?

The best Milio runes against Seraphine use the Sorcery primary tree with Inspiration secondary. This rune setup achieves a 54.5% win rate in the Milio vs Seraphine matchup. See the full rune breakdown in the matchup comparison above.

Does Milio counter Seraphine?

Yes, Milio has a favorable matchup against Seraphine with a 55.6% win rate. Milio strongly counters Seraphine in lane based on current patch 26.7 data.

How do I play Milio against Seraphine?

When playing Milio against Seraphine, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.