Seraphine - League of Legends Champion
Win Rate
52.1%
Pick Rate
7.6%

Seraphinevs Milio

SSupportMage
Patch26.11
Matches776,441
LaneAll Lanes
TierAll Tiers
Last UpdatedJun 10, 2026
MethodologyData Methodology

Seraphine vs Milio is a very close matchup in LoL patch 26.11. Seraphine wins with a 50.0% win rate (+0.0%) over Milio based on 334 games. Seraphine wins the early laning phase while Milio scales better into the late game. Below you'll find the best Seraphine build, runes, laning stats, and strategies for the Seraphine vs Milio matchup.

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Seraphine Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Seraphine performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Seraphine - 50.0% win rate in this matchup
Seraphine
50.0% WR
VS
Milio vs Seraphine matchup - 50.0% win rate
Milio
50.0% WR

Who Wins the Seraphine vs Milio Matchup?

Seraphine wins the Seraphine vs Milio matchup
Winner
Seraphine
Matches: 334
50.0%
Win Rate
50.0%
1.4
CS / min
1.0
453
DMG / min
198
9,010
Gold / game
8,382
300
Heal / min
448
361
DMG Mitigated / min
352
1.1
CC / min
0.7
50.4%
Early Game WR
49.6%
49.7%
Late Game WR
50.3%

Seraphine vs Milio Matchup Summary

The Seraphine vs Milio matchup is essentially a coin-flip matchup in League of Legends ranked play. Based on 334 recent matches analyzed, Seraphine wins with a 50.0% win rate compared to Milio's 50.0%, giving Seraphine a 0.0 percentage point advantage. Game phase dynamics play a critical role here: Seraphine controls the early laning stage, but Milio outscales as the game goes longer. The matchup shifts dramatically depending on game length — Seraphine needs to press advantages before Milio reaches their power spikes, while Milio should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in damage output, where Seraphine leads by 255 DMG/min — a difference that heavily influences the outcome of trades and skirmishes. Seraphine has a statistical edge, but the margin is close enough that respecting Milio's strengths is important. Trade when cooldowns are favorable, track the enemy jungler, and build toward your strongest item spikes to convert the slight advantage into a decisive lead. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Seraphine vs Milio Laning Phase Breakdown

Seraphine wins the laning phase against Milio in League of Legends

Seraphine is favored during the laning phase against Milio, winning 4 out of 5 key stat categories. Seraphine holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.

Farming
1.4Seraphine
1.0Milio
Seraphine edges out Milio by 0.4 CS per minute — a moderate farming advantage that adds up to roughly 6 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Seraphine.
Damage
453Seraphine
198Milio
Seraphine heavily out-damages Milio by 255 DMG/min, dominating both short trades and all-in fights. Milio should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Seraphine's sustained damage advantage take over.
Economy
9,010Seraphine
8,382Milio
Seraphine earns 628 more gold per game than Milio, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Seraphine slightly faster item completions.
Utility
1.1Seraphine
0.7Milio
Seraphine provides 0.4 seconds more crowd control per minute than Milio, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Seraphine coordinate with their jungler and control the pace of skirmishes.
Sustain
662Seraphine
801Milio
Milio heals and mitigates 139 more damage per minute than Seraphine, providing moderate extra durability. This sustain edge allows Milio to stay in lane longer between recalls and gradually win extended wars of attrition. Consider building early grievous wounds if playing Seraphine.

Best Seraphine Build Against Milio

Ionian Boots of Lucidity is the optimal boots choice against Milio, providing the mobility and stats Seraphine needs most in this matchup. The top-performing core items for Seraphine against Milio are Moonstone Renewer, Rylai's Crystal Scepter and Diadem of Songs. This combination gives Seraphine an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 80.0% win rate across 5 games — well above average and making it the top item path against Milio. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Seraphine vs Milio matchup.

Early Game vs Late Game

Early Game
Seraphine
50.4%
+0.7% advantage
Seraphine early game win rateSeraphine50.4%
Milio early game win rateMilio49.6%
Late Game
Milio
50.3%
+0.5% advantage
Seraphine late game win rateSeraphine49.7%
Milio late game win rateMilio50.3%

The early game (first 15 minutes) is a toss-up between Seraphine and Milio, with Seraphine holding a razor-thin 50.4% win rate edge (+0.7%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.

Late game (25+ minutes) is equally balanced, with Milio at 50.3% win rate — only 0.5 points ahead of Seraphine. Team fight execution and macro play determine the winner at this stage, not champion matchup advantage.

The power dynamics shift as the game progresses — Seraphine has the edge early, but Milio gradually takes over. However, the margins are slim enough that either champion can win at any stage with the right plays. Focus on taking advantages when you have them rather than waiting for a specific game phase.

Best Seraphine Runes Against Milio

Sorcery rune tree - Seraphine primary runes vs MilioSorcery
Summon Aery - best Seraphine rune vs MilioManaflow Band - best Seraphine rune vs MilioTranscendence - best Seraphine rune vs MilioScorch - best Seraphine rune vs Milio
Inspiration rune tree - Seraphine secondary runes vs MilioInspiration
Biscuit Delivery - best Seraphine rune vs MilioCosmic Insight - best Seraphine rune vs Milio
54.5% WR

The Sorcery primary with Inspiration secondary combination helps Seraphine maximize their potential in this closely contested matchup, providing the right mix of offensive and defensive tools to edge out Milio.


Seraphine matchup data for League of Legends patch 26.11. The table below shows Seraphine's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Seraphine build, runes, laning stats, and early vs late game analysis for that specific matchup.

Seraphine matchup win rates and stats in League of Legends patch 26.11
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
47.75%7791.74669,35944.9%49.5%
50.91%5501.44939,17358.0%45.0%
49.45%5481.44879,00751.2%48.0%
50.83%5431.44879,19746.8%53.9%
52.69%5011.54979,35248.8%55.5%
50.21%4781.85269,25551.6%49.0%
48.69%4211.54709,01249.2%48.3%
50.00%3341.44539,01050.4%49.7%
50.91%3301.95249,71553.4%49.2%
51.72%3191.44699,56046.7%55.4%
52.44%3071.44938,93052.7%52.2%
53.17%2841.74839,53147.7%56.6%
52.84%2821.44878,90149.2%55.8%
50.78%2581.54449,24750.5%51.0%
47.97%2461.54669,32744.7%50.4%
54.85%2371.85849,76454.8%54.9%
54.85%2371.44528,96551.9%57.4%
53.07%2281.53918,66358.8%46.8%
54.63%2271.84989,66455.6%54.0%
43.13%2111.35028,90135.6%48.8%
52.22%2031.45229,03758.4%47.4%
43.22%1991.54988,96147.1%40.4%
48.44%1921.44979,41851.2%46.3%
53.45%1741.84629,23249.4%56.7%
49.70%1691.66149,70344.4%52.2%
52.26%1551.44799,11856.9%48.2%
57.53%1461.45699,69067.9%51.1%
54.48%1454.566211,52162.3%50.0%
52.52%1391.44899,05164.1%42.7%
61.29%1241.64819,07567.7%54.8%
50.00%1221.44628,51250.8%49.1%
50.00%1201.45089,23252.8%47.8%
51.30%1151.44638,90542.2%57.1%
59.13%1156.281412,23054.7%62.9%
53.49%861.54809,03567.5%41.3%
54.88%825.867711,89860.0%51.9%
61.25%804.878912,00275.9%52.9%
56.76%746.880712,47863.9%50.0%
53.42%732.05109,99152.0%54.2%
56.16%731.55149,44956.8%55.6%
46.88%641.54679,51052.0%43.6%
43.33%601.65579,12160.7%28.1%
48.33%602.14408,59548.3%48.4%
54.24%596.283112,84042.1%60.0%
54.24%593.359210,05860.9%50.0%
60.34%585.375111,90651.9%67.7%
63.16%572.056710,73279.0%55.3%
44.23%521.75759,42052.0%37.0%
51.06%472.04629,10847.6%53.9%
50.00%402.260810,02652.6%47.6%
56.76%376.389112,39562.5%52.4%
44.44%362.55159,08730.8%52.2%
60.61%334.259811,53455.6%62.5%
51.52%335.366611,60061.5%45.0%
42.42%336.281310,73542.1%42.9%
51.52%336.878711,42658.8%43.8%
65.63%321.64749,16373.3%58.8%
65.63%324.168110,15666.7%64.7%
58.06%311.64859,79966.7%52.6%
56.67%306.673310,93362.5%50.0%
41.38%291.45019,36630.8%50.0%
44.44%275.167710,72263.6%31.3%
62.96%271.649810,32862.5%63.2%
54.17%244.26249,65645.5%61.5%
50.00%222.45679,74940.0%58.3%
45.45%223.04909,41825.0%57.1%
63.64%222.250811,56760.0%64.7%
40.00%206.580113,55633.3%41.2%
55.00%206.779212,47966.7%45.5%
55.00%202.04629,45857.1%53.9%
45.00%205.871411,07240.0%50.0%
70.00%201.464510,69887.5%58.3%
63.16%191.443410,16060.0%64.3%
61.11%185.67038,05964.3%50.0%
58.82%176.286512,02650.0%63.6%
35.29%171.244610,23775.0%23.1%
75.00%166.791813,62771.4%77.8%
37.50%161.54798,92840.0%36.4%
60.00%156.776112,98866.7%55.6%
40.00%155.359710,54633.3%44.4%
60.00%151.646310,50775.0%54.5%
50.00%143.264710,32850.0%50.0%
50.00%142.65519,74250.0%50.0%
42.86%144.85849,77450.0%37.5%
53.85%136.392112,20066.7%42.9%
30.77%134.16039,87733.3%28.6%
61.54%133.15949,46842.9%83.3%
58.33%126.78259,19670.0%0.0%
50.00%124.36669,42433.3%66.7%
58.33%126.076411,19160.0%57.1%
72.73%116.175811,907100.0%66.7%
27.27%114.55499,3630.0%50.0%
54.55%116.266011,06050.0%60.0%
60.00%105.680311,24250.0%75.0%
80.00%101.44777,16187.5%50.0%
66.67%94.552110,244100.0%62.5%
44.44%91.84238,69366.7%33.3%
37.50%86.293011,95740.0%33.3%
62.50%81.66239,74233.3%80.0%
37.50%81.53958,01025.0%50.0%
37.50%81.34679,59625.0%50.0%
25.00%85.367010,06850.0%16.7%
25.00%83.45779,67325.0%25.0%
62.50%81.457011,7740.0%71.4%
75.00%85.470711,28850.0%83.3%
50.00%81.14638,69050.0%50.0%
50.00%86.298713,25366.7%40.0%
75.00%81.648710,73550.0%83.3%
85.71%71.45378,417100.0%0.0%
42.86%71.949210,03133.3%50.0%
71.43%73.163510,657100.0%60.0%
57.14%73.473912,184100.0%50.0%
100.00%73.15957,466100.0%100.0%
71.43%73.05208,01175.0%66.7%
33.33%67.382210,97625.0%50.0%
100.00%62.35489,903100.0%100.0%
83.33%62.247410,918100.0%80.0%
50.00%61.63829,86350.0%50.0%
100.00%55.957011,5490.0%100.0%
40.00%51.649610,44750.0%33.3%
60.00%51.256510,3000.0%75.0%
40.00%56.06469,77425.0%100.0%
40.00%53.864610,54966.7%0.0%
80.00%51.549910,15550.0%100.0%

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Seraphine vs Milio - Frequently Asked Questions

How does Seraphine do against Milio in League of Legends?

Seraphine wins the Seraphine vs Milio matchup with a 50.0% win rate compared to Milio's 50.0%, a 0.0 percentage point difference. This data is based on 334 recent ranked games in patch 26.11.

How does Seraphine do against Milio in the early game?

In the early game, Seraphine has the advantage against Milio with a 50.4% win rate versus 49.6%. Seraphine players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Seraphine do against Milio in the late game?

In the late game, Milio takes over the Seraphine vs Milio matchup with a 50.3% win rate compared to 49.7%. Milio scales better into team fights and objective contests after 25 minutes.

Who wins the Seraphine vs Milio matchup?

Seraphine wins the matchup against Milio with a 50.0% win rate in League of Legends patch 26.11. The 0.0 percentage point advantage means Seraphine is slightly favored in this lane matchup based on 334 games analyzed.

What is the best Seraphine build against Milio?

The best Seraphine build against Milio includes Moonstone Renewer, Rylai's Crystal Scepter, Diadem of Songs with Ionian Boots of Lucidity. This build achieves a 80.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Seraphine runes against Milio?

The best Seraphine runes against Milio use the Sorcery primary tree with Inspiration secondary. This rune setup achieves a 54.5% win rate in the Seraphine vs Milio matchup. See the full rune breakdown in the matchup comparison above.

Does Seraphine counter Milio?

Yes, Seraphine has a favorable matchup against Milio with a 50.0% win rate. Seraphine slightly edges out Milio in lane based on current patch 26.11 data.

How do I play Seraphine against Milio?

When playing Seraphine against Milio, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.