
Nasusvs Vayne
Nasus vs Vayne is a very close matchup in LoL patch 26.19. Nasus wins with a 50.0% win rate (+0.0%) over Vayne based on 32 games. Nasus wins the early laning phase while Vayne scales better into the late game. Below you'll find the best Nasus build, runes, laning stats, and strategies for the Nasus vs Vayne matchup.
Nasus Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Nasus performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.


Who wins Nasus vs Vayne?
Nasus wins 54.4% of these games. With this many games the true rate is most likely between 42.7% and 65.7% (95% range).
- Expected
- 52.0% From both champions' overall Top win rates
- Matchup effect
- +2.5 pts Observed minus expected
- Sample
- 68 games Lane: Top
- vs patch 26.18
- −18.8 pts A real change since last patch
Lane: Top · Ranked Solo/Duo & Flex · North America server · All ranks · Patch 26.19 · Sep 24 – Sep 28
Key takeaways
- Current data slightly favors Nasus, but the sample is too limited for a strong conclusion: Nasus wins 54.4% of 68 games (95% range 42.7–65.7%).
- Both champions' overall Top win rates predict 52.0% for Nasus; the result is within the margin of error of that, so this matchup mostly reflects the two champions' general strength.
- Nasus usually wins the lane: 512 gold ahead of Vayne at 15 minutes on average (68 games with a 15-minute snapshot).
- Nasus players pick Scorch far more often against Vayne: 17.0% of their other Top games, 32.4% here.
How we calculate this
Games: ranked Solo/Duo and Flex games on the North America server from the patch shown. Remakes (games under 5 minutes) are excluded.
A game only counts when Nasus and Vayne played the same position on opposite teams, so roaming, lane swaps within a team or a champion merely being in the same game never count as this matchup.
The 95% range is a Wilson score interval. Confidence comes from how wide that range is: within ±3 points is very high, ±5 high, ±8 moderate, anything wider low. Below 20 games a matchup is not classified at all.
Expected win rate combines both champions’ win rates in this lane (same games and filters) with the log5 formula: E = A(1−B) / (A(1−B) + B(1−A)). Matchup effect = observed − expected.
"What changes" compares Nasus's choices in this matchup with the same champion's other games in the same lane, and lists a change only when it is at least 3 points and statistically significant (two-proportion z-test, |z| ≥ 2, 20+ games).
Results are not split by rank: the sample per rank is too small for honest per-rank matchup numbers.
Nasus vs Vayne Laning Stats
At 15 minutes
Whole-game averages
Nasus vs Vayne Win Rate by Game Length
Nasus's win rate against Vayne by game length. The dot is the win rate, the bar its 95% range and the dashed line the champion's usual win rate at that length. Lengths with fewer than 25 games are left blank.
No game length stands out: Nasus's results against Vayne in short and long games are within the margin of error of each other.
Nasus vs Vayne Power Spikes
Who is ahead at each stage, measured from these games. A stage reads "Even" when the difference is inside the margin of error, and "Insufficient data" when there are too few games to tell.
- Lane (15 min)NasusNasus gold at 15: +512
- First itemNasusNasus: 14.7 min · Vayne: 15.4 min
- Games under 20 minInsufficient data
- 20–30 min gamesInsufficient data
- 30+ min gamesInsufficient data
What Nasus Changes Against Vayne
Choices Nasus players make noticeably more or less often in this matchup than in their other Top games.
ScorchRuneUsually17.0%vs Vayne32.4%+15.3 pts68.2% WR here
Mercury's TreadsBootsUsually21.1%vs Vayne5.9%−15.2 pts
Plated SteelcapsBootsUsually29.4%vs Vayne44.1%+14.7 pts50.0% WR here
Manaflow BandRuneUsually18.9%vs Vayne32.4%+13.4 pts68.2% WR here
Biscuit DeliveryRuneUsually14.6%vs Vayne23.5%+8.9 pts
Summon AeryKeystoneUsually4.4%vs Vayne10.3%+5.9 pts
Usually1.2%vs Vayne4.4%+3.2 pts
Best Nasus Build vs Vayne
Usual Nasus build (Top)
90.0% win rate · 10 games
Against Vayne
Not enough matchup-specific build data: only 5 of 42 Nasus games against Vayne carried a complete build, which is too few to recommend an item path from. Use Nasus's standard build instead.
- Nasus usually completes Trinity Force first, at 14.7 min (median of 32 games).
- Vayne usually completes Blade of The Ruined King first, at 15.4 min (median of 44 games).
- Skill priority: Q > W > E — the same as usual.
Builds are ranked by the lower edge of their win rate range, not the raw win rate, so a build seen in a handful of wins never outranks a proven one.
Best Nasus Runes vs Vayne
Plan your Nasus draft in Draft Lab
Draft Lab lays out both teams lane by lane with live matchup win rates, damage profiles and game-phase lean, and suggests picks and bans from current meta data.
- Full 5v5 draft board
- Lane matchup win rates
- Pick and ban suggestions

Nasus matchup data for League of Legends patch 26.19. The table below shows Nasus's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Nasus build, runes, laning stats, and early vs late game analysis for that specific matchup.
Other Nasus Matchups
Hardest for Nasus
Easiest for Nasus
Win rate and games for each matchup. Lists are ranked by the edge of the 95% range so small samples cannot top them; matchups with at least 50 games only.
Help us maintain accuracy! If you notice incorrect stats, missing data, or any issues, your feedback directly improves the quality of our data for the entire community.
Nasus vs Vayne FAQ - Patch 26.19
Who wins Nasus vs Vayne?
Current data slightly favors Nasus, but the sample is too limited for a strong conclusion: Nasus wins 54.4% of 68 games (95% range 42.7–65.7%).
What is Nasus's win rate against Vayne?
Nasus wins 54.4% of 68 Top games against Vayne on patch 26.19 (95% range 42.7–65.7%). Based on both champions' overall Top win rates, 52.0% would be expected.
Does Nasus counter Vayne?
Not clearly. Nasus wins 54.4% of 68 games against Vayne, and the 95% range (42.7–65.7%) includes 50%, so neither champion reliably counters the other on current data.
Who wins lane, Nasus or Vayne?
Nasus usually wins the lane: 512 gold ahead of Vayne at 15 minutes on average (68 games with a 15-minute snapshot).
Does Nasus outscale Vayne?
There are too few games of each length to tell yet.
When is Vayne strongest against Nasus?
On current data there is no stage of the game where Vayne is ahead of Nasus beyond the margin of error.
What should Nasus build against Vayne?
There are not enough games for a matchup-specific core, so use Nasus's usual Top core: Iceborn Gauntlet, Force of Nature, Dead Man's Plate. The biggest change against Vayne: Mercury's Treads (21.1% usually, 5.9% here).
What runes should Nasus use against Vayne?
Fleet Footwork with Precision and Resolve — 50.0% over 32 games against Vayne. The biggest change against Vayne: Scorch (17.0% usually, 32.4% here).
