
Nasusvs Vayne
Nasus vs Vayne is a moderate matchup in LoL patch 26.11. Vayne wins with a 51.9% win rate (+3.8%) over Nasus based on 52 games. Nasus wins the early laning phase while Vayne scales better into the late game. Below you'll find the best Nasus build, runes, laning stats, and strategies for the Nasus vs Vayne matchup.
Nasus Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Nasus performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Nasus vs Vayne Matchup?

Nasus vs Vayne Matchup Summary
The Nasus vs Vayne matchup is a moderate matchup in League of Legends ranked play. Based on 52 recent matches analyzed, Vayne wins with a 51.9% win rate compared to Nasus's 48.1%, giving Vayne a 3.8 percentage point advantage. Game phase dynamics play a critical role here: Nasus controls the early laning stage, but Vayne outscales as the game goes longer. The matchup shifts dramatically depending on game length — Nasus needs to press advantages before Vayne reaches their power spikes, while Vayne should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in sustain, where Nasus leads by 1,142 HP/min — a difference that heavily influences the outcome of trades and skirmishes. While Vayne is slightly favored, Nasus can absolutely win this lane through smart trading patterns and wave management. Focus on playing around your cooldowns, conceding CS only when necessary, and capitalizing on Vayne's mistakes. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Nasus vs Vayne Laning Phase Breakdown
Nasus is favored during the laning phase against Vayne, winning 4 out of 5 key stat categories. Nasus holds advantages in farming, gold income, crowd control and sustain, making them the stronger laner in this matchup.
Best Nasus Build Against Vayne
Plated Steelcaps is the optimal boots choice against Vayne, providing the mobility and stats Nasus needs most in this matchup. The top-performing core items for Nasus against Vayne are Frozen Heart, Trinity Force and Thornmail. This combination gives Nasus an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 60.0% win rate across 5 games — well above average and making it the top item path against Vayne. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Nasus vs Vayne matchup.
Early Game vs Late Game
During the early laning phase (first 15 minutes), Nasus has a meaningful 51.9% win rate, outperforming Vayne by 3.7 percentage points. Nasus players should look to press this advantage through aggressive trades, wave priority, and early jungle coordination.
Vayne is far superior in the late game (25+ minutes), boasting a 56.0% win rate — 12.0 points above Nasus. Extended games heavily favor Vayne, whose kit and scaling make them a dominant force in team fights and objective control.
This matchup features a dramatic power shift: Nasus must aggressively press their early advantage and close out the game before Vayne reaches their scaling breakpoints. If Vayne survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.
Best Nasus Runes Against Vayne
The Sorcery and Precision rune setup gives Nasus the best tools to compete against Vayne in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.
Nasus matchup data for League of Legends patch 26.11. The table below shows Nasus's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Nasus build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 45.83% | 216 | 6.3 | 719 | 11,290 | 38.5% | 51.2% | |
| 40.11% | 182 | 5.9 | 642 | 11,617 | 46.4% | 36.3% | |
| 57.76% | 161 | 5.8 | 754 | 11,791 | 54.8% | 59.6% | |
| 48.18% | 137 | 6.0 | 851 | 11,615 | 52.6% | 45.0% | |
| 53.33% | 135 | 5.7 | 709 | 11,464 | 56.4% | 51.3% | |
| 48.06% | 129 | 6.4 | 719 | 12,083 | 50.0% | 46.8% | |
| 48.00% | 125 | 6.4 | 725 | 11,582 | 50.9% | 45.8% | |
| 49.14% | 116 | 6.1 | 707 | 11,749 | 40.8% | 55.2% | |
| 45.10% | 102 | 6.5 | 825 | 11,876 | 36.8% | 50.0% | |
| 43.16% | 95 | 5.7 | 768 | 10,822 | 36.2% | 50.0% | |
| 48.39% | 93 | 5.1 | 728 | 11,189 | 42.9% | 52.9% | |
| 45.98% | 87 | 6.4 | 823 | 11,807 | 41.0% | 50.0% | |
| 48.24% | 85 | 5.7 | 762 | 11,934 | 55.2% | 44.6% | |
| 38.55% | 83 | 5.9 | 789 | 11,121 | 36.1% | 40.4% | |
| 53.09% | 81 | 6.1 | 1,128 | 11,538 | 45.2% | 61.5% | |
| 48.65% | 74 | 2.6 | 697 | 11,518 | 47.2% | 50.0% | |
| 54.79% | 73 | 6.5 | 837 | 11,926 | 61.5% | 51.1% | |
| 54.29% | 70 | 7.1 | 810 | 12,807 | 36.7% | 67.5% | |
| 42.03% | 69 | 6.2 | 623 | 10,959 | 45.5% | 38.9% | |
| 36.92% | 65 | 6.4 | 777 | 11,165 | 55.6% | 23.7% | |
| 49.23% | 65 | 5.5 | 762 | 11,503 | 50.0% | 48.6% | |
| 50.77% | 65 | 2.0 | 725 | 12,625 | 50.0% | 51.1% | |
| 41.54% | 65 | 5.9 | 869 | 12,545 | 30.8% | 48.7% | |
| 64.62% | 65 | 6.7 | 788 | 13,305 | 75.0% | 58.5% | |
| 55.56% | 63 | 6.5 | 750 | 11,428 | 56.7% | 54.5% | |
| 56.45% | 62 | 6.3 | 704 | 12,248 | 47.8% | 61.5% | |
| 54.24% | 59 | 6.5 | 722 | 11,842 | 56.5% | 52.8% | |
| 55.17% | 58 | 3.7 | 816 | 12,248 | 66.7% | 42.9% | |
| 51.79% | 56 | 6.1 | 661 | 11,068 | 48.1% | 55.2% | |
| 52.73% | 55 | 6.5 | 781 | 13,080 | 70.0% | 42.9% | |
| 59.26% | 54 | 3.3 | 775 | 12,128 | 64.0% | 55.2% | |
| 55.56% | 54 | 6.0 | 724 | 12,318 | 55.0% | 55.9% | |
| 44.44% | 54 | 5.5 | 781 | 10,451 | 40.0% | 48.3% | |
| 53.70% | 54 | 2.3 | 707 | 12,305 | 38.1% | 63.6% | |
| 54.72% | 53 | 6.3 | 665 | 12,458 | 52.9% | 55.6% | |
| 48.08% | 52 | 6.1 | 636 | 11,710 | 51.9% | 44.0% | |
| 66.67% | 51 | 2.1 | 767 | 13,437 | 63.6% | 69.0% | |
| 35.42% | 48 | 5.6 | 803 | 10,254 | 31.8% | 38.5% | |
| 45.83% | 48 | 5.4 | 776 | 10,587 | 44.0% | 47.8% | |
| 48.94% | 47 | 6.5 | 807 | 12,312 | 42.1% | 53.6% | |
| 67.44% | 43 | 1.4 | 772 | 12,942 | 70.6% | 65.4% | |
| 59.52% | 42 | 6.4 | 776 | 12,349 | 52.9% | 64.0% | |
| 52.38% | 42 | 1.1 | 634 | 12,533 | 50.0% | 53.3% | |
| 59.52% | 42 | 3.9 | 664 | 12,615 | 60.0% | 59.3% | |
| 31.71% | 41 | 5.3 | 886 | 12,136 | 42.9% | 25.9% | |
| 51.22% | 41 | 6.0 | 732 | 11,687 | 62.5% | 44.0% | |
| 52.50% | 40 | 2.3 | 799 | 12,921 | 41.2% | 60.9% | |
| 50.00% | 40 | 1.8 | 706 | 12,596 | 50.0% | 50.0% | |
| 61.54% | 39 | 5.8 | 730 | 12,357 | 66.7% | 59.3% | |
| 61.54% | 39 | 6.2 | 710 | 11,312 | 47.6% | 77.8% | |
| 63.64% | 33 | 6.1 | 728 | 13,153 | 60.0% | 65.2% | |
| 56.25% | 32 | 4.1 | 717 | 13,265 | 54.5% | 57.1% | |
| 58.06% | 31 | 3.7 | 789 | 11,792 | 43.8% | 73.3% | |
| 53.33% | 30 | 3.7 | 650 | 12,294 | 42.9% | 62.5% | |
| 58.62% | 29 | 6.6 | 772 | 10,669 | 41.7% | 70.6% | |
| 50.00% | 28 | 1.9 | 749 | 13,922 | 57.1% | 47.6% | |
| 46.43% | 28 | 6.6 | 812 | 10,956 | 61.5% | 33.3% | |
| 77.78% | 27 | 6.0 | 811 | 12,165 | 100.0% | 64.7% | |
| 51.85% | 27 | 1.6 | 755 | 13,245 | 50.0% | 52.6% | |
| 53.85% | 26 | 1.9 | 772 | 12,457 | 50.0% | 57.1% | |
| 50.00% | 24 | 6.8 | 707 | 11,742 | 72.7% | 30.8% | |
| 52.17% | 23 | 3.5 | 741 | 12,325 | 41.7% | 63.6% | |
| 65.22% | 23 | 4.8 | 853 | 12,358 | 45.5% | 83.3% | |
| 59.09% | 22 | 6.4 | 682 | 12,361 | 50.0% | 64.3% | |
| 63.64% | 22 | 6.8 | 681 | 10,185 | 66.7% | 60.0% | |
| 47.62% | 21 | 6.5 | 753 | 11,169 | 55.6% | 41.7% | |
| 40.00% | 20 | 5.6 | 640 | 11,227 | 50.0% | 30.0% | |
| 40.00% | 20 | 2.0 | 669 | 12,702 | 42.9% | 38.5% | |
| 30.00% | 20 | 1.2 | 774 | 12,346 | 18.2% | 44.4% | |
| 42.11% | 19 | 2.5 | 666 | 11,065 | 50.0% | 33.3% | |
| 50.00% | 18 | 2.1 | 821 | 12,978 | 37.5% | 60.0% | |
| 50.00% | 18 | 6.7 | 829 | 9,717 | 50.0% | 50.0% | |
| 55.56% | 18 | 3.2 | 800 | 11,994 | 50.0% | 60.0% | |
| 23.53% | 17 | 6.1 | 614 | 11,481 | 22.2% | 25.0% | |
| 64.71% | 17 | 1.9 | 817 | 13,175 | 50.0% | 72.7% | |
| 25.00% | 16 | 1.9 | 727 | 13,557 | 50.0% | 10.0% | |
| 37.50% | 16 | 7.2 | 775 | 13,202 | 62.5% | 12.5% | |
| 56.25% | 16 | 2.9 | 729 | 13,079 | 50.0% | 60.0% | |
| 31.25% | 16 | 1.6 | 712 | 12,100 | 14.3% | 44.4% | |
| 50.00% | 16 | 6.7 | 733 | 11,321 | 40.0% | 54.5% | |
| 50.00% | 16 | 5.9 | 691 | 13,523 | 66.7% | 40.0% | |
| 43.75% | 16 | 6.6 | 928 | 10,357 | 33.3% | 57.1% | |
| 46.67% | 15 | 5.7 | 627 | 12,594 | 50.0% | 44.4% | |
| 46.67% | 15 | 4.9 | 1,023 | 12,140 | 66.7% | 33.3% | |
| 46.67% | 15 | 1.9 | 783 | 12,817 | 33.3% | 55.6% | |
| 66.67% | 15 | 5.3 | 874 | 14,640 | 33.3% | 88.9% | |
| 57.14% | 14 | 6.6 | 648 | 12,218 | 57.1% | 57.1% | |
| 50.00% | 14 | 1.1 | 681 | 11,342 | 42.9% | 57.1% | |
| 50.00% | 14 | 2.7 | 599 | 10,570 | 44.4% | 60.0% | |
| 35.71% | 14 | 1.8 | 608 | 11,856 | 33.3% | 40.0% | |
| 53.85% | 13 | 6.3 | 697 | 11,117 | 42.9% | 66.7% | |
| 61.54% | 13 | 5.9 | 716 | 12,304 | 50.0% | 71.4% | |
| 41.67% | 12 | 6.1 | 826 | 10,284 | 42.9% | 40.0% | |
| 58.33% | 12 | 4.4 | 1,040 | 13,869 | 66.7% | 55.6% | |
| 63.64% | 11 | 6.0 | 606 | 13,053 | 66.7% | 60.0% | |
| 60.00% | 10 | 5.7 | 737 | 10,573 | 40.0% | 80.0% | |
| 55.56% | 9 | 6.7 | 654 | 13,240 | 100.0% | 42.9% | |
| 44.44% | 9 | 4.3 | 638 | 11,394 | 33.3% | 50.0% | |
| 55.56% | 9 | 6.7 | 741 | 10,796 | 60.0% | 50.0% | |
| 66.67% | 9 | 5.5 | 713 | 13,796 | 66.7% | 66.7% | |
| 44.44% | 9 | 5.1 | 718 | 12,980 | 66.7% | 33.3% | |
| 50.00% | 8 | 3.0 | 443 | 9,956 | 66.7% | 40.0% | |
| 50.00% | 8 | 5.8 | 806 | 11,354 | 60.0% | 33.3% | |
| 25.00% | 8 | 6.2 | 611 | 10,051 | 0.0% | 40.0% | |
| 25.00% | 8 | 6.5 | 557 | 11,107 | 33.3% | 20.0% | |
| 75.00% | 8 | 1.2 | 809 | 13,893 | 50.0% | 83.3% | |
| 14.29% | 7 | 6.3 | 482 | 9,385 | 0.0% | 33.3% | |
| 28.57% | 7 | 2.9 | 667 | 11,986 | 66.7% | 0.0% | |
| 28.57% | 7 | 0.8 | 437 | 8,994 | 20.0% | 50.0% | |
| 42.86% | 7 | 1.1 | 575 | 11,481 | 100.0% | 20.0% | |
| 66.67% | 6 | 1.6 | 869 | 14,638 | 0.0% | 66.7% | |
| 66.67% | 6 | 7.3 | 880 | 12,437 | 50.0% | 75.0% | |
| 0.00% | 6 | 3.2 | 612 | 10,318 | 0.0% | 0.0% | |
| 50.00% | 6 | 6.1 | 758 | 13,393 | 33.3% | 66.7% | |
| 50.00% | 6 | 6.7 | 823 | 11,083 | 33.3% | 66.7% | |
| 40.00% | 5 | 4.7 | 772 | 12,767 | 50.0% | 33.3% | |
| 40.00% | 5 | 4.3 | 651 | 13,499 | 0.0% | 66.7% | |
| 20.00% | 5 | 5.8 | 612 | 12,870 | 100.0% | 0.0% | |
| 80.00% | 5 | 6.3 | 768 | 14,171 | 66.7% | 100.0% | |
| 40.00% | 5 | 2.6 | 635 | 12,399 | 0.0% | 66.7% | |
| 60.00% | 5 | 5.2 | 641 | 7,987 | 66.7% | 50.0% | |
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Nasus vs Vayne - Frequently Asked Questions
How does Nasus do against Vayne in League of Legends?
Vayne wins the Nasus vs Vayne matchup with a 51.9% win rate compared to Nasus's 48.1%, a 3.8 percentage point difference. This data is based on 52 recent ranked games in patch 26.11.
How does Nasus do against Vayne in the early game?
In the early game, Nasus has the advantage against Vayne with a 51.9% win rate versus 48.1%. Nasus players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Nasus do against Vayne in the late game?
In the late game, Vayne takes over the Nasus vs Vayne matchup with a 56.0% win rate compared to 44.0%. Vayne scales better into team fights and objective contests after 25 minutes.
Who wins the Nasus vs Vayne matchup?
Vayne wins the matchup against Nasus with a 51.9% win rate in League of Legends patch 26.11. The 3.8 percentage point advantage means Vayne is moderately favored in this lane matchup based on 52 games analyzed.
What is the best Nasus build against Vayne?
The best Nasus build against Vayne includes Frozen Heart, Trinity Force, Thornmail with Plated Steelcaps. This build achieves a 60.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.
What are the best Nasus runes against Vayne?
The best Nasus runes against Vayne use the Sorcery primary tree with Precision secondary. This rune setup achieves a 100.0% win rate in the Nasus vs Vayne matchup. See the full rune breakdown in the matchup comparison above.
Does Nasus counter Vayne?
No, Nasus struggles against Vayne with only a 48.1% win rate. Vayne has the advantage in this matchup. Nasus players should focus on safe farming and avoiding extended trades to minimize Vayne's lead.
How do I play Nasus against Vayne?
When playing Nasus against Vayne, play cautiously and avoid Vayne's power spikes. Look for jungle assistance and team-dependent plays since Vayne has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.
