
Nasusvs Vayne
Nasus vs Vayne is a decisive matchup in LoL patch 26.14. Nasus wins with a 61.3% win rate (+22.6%) over Vayne based on 31 games. Nasus holds the advantage in both the early and late game. Below you'll find the best Nasus build, runes, laning stats, and strategies for the Nasus vs Vayne matchup.
Nasus Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Nasus performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Nasus vs Vayne Matchup?

Nasus vs Vayne Matchup Summary
The Nasus vs Vayne matchup is a decisive matchup in League of Legends ranked play. Based on 31 recent matches analyzed, Nasus wins with a 61.3% win rate compared to Vayne's 38.7%, giving Nasus a 22.6 percentage point advantage. Nasus dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Vayne players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Nasus leads by 1,174 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Nasus players can confidently pick into Vayne and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Vayne away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Nasus vs Vayne Laning Phase Breakdown
Vayne is favored during the laning phase against Nasus, winning 3 out of 5 key stat categories. Vayne holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.
Best Nasus Build Against Vayne
Ionian Boots of Lucidity is the optimal boots choice against Vayne, providing the mobility and stats Nasus needs most in this matchup. The top-performing core items for Nasus against Vayne are Frozen Heart, Trinity Force and Thornmail. This combination gives Nasus an effective balance of damage, survivability, and utility for the matchup. This build has a 33.3% win rate across 3 games. While the overall matchup may be difficult, this item path gives Nasus the best chance to compete against Vayne. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Nasus vs Vayne matchup.
Early Game vs Late Game
Nasus dominates the early game (first 15 minutes) with a commanding 72.7% win rate — a 45.5 percentage point lead over Vayne. This lopsided early game means Nasus can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Nasus is far superior in the late game (25+ minutes), boasting a 55.0% win rate — 10.0 points above Vayne. Extended games heavily favor Nasus, whose kit and scaling make them a dominant force in team fights and objective control.
Nasus holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Vayne players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.
Best Nasus Runes Against Vayne
Running Precision primary with Resolve secondary allows Nasus to press their advantage against Vayne, amplifying the strengths that make this a favorable matchup.
Nasus matchup data for League of Legends patch 26.14. The table below shows Nasus's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Nasus build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 47.89% | 142 | 1.3 | 723 | 11,718 | 45.5% | 49.4% | |
| 45.32% | 139 | 5.4 | 739 | 10,529 | 38.6% | 50.0% | |
| 44.35% | 124 | 6.4 | 710 | 11,562 | 52.3% | 40.0% | |
| 52.54% | 118 | 1.6 | 703 | 11,592 | 44.2% | 59.1% | |
| 47.75% | 111 | 1.7 | 642 | 11,170 | 50.0% | 46.1% | |
| 49.54% | 109 | 1.1 | 647 | 11,140 | 46.0% | 52.5% | |
| 47.22% | 108 | 1.3 | 693 | 12,148 | 43.2% | 49.3% | |
| 49.02% | 102 | 1.2 | 717 | 12,129 | 47.2% | 50.0% | |
| 49.47% | 95 | 1.2 | 588 | 11,310 | 38.5% | 57.1% | |
| 51.61% | 93 | 5.7 | 667 | 11,639 | 48.1% | 53.0% | |
| 54.35% | 92 | 5.8 | 832 | 11,203 | 50.0% | 58.0% | |
| 48.91% | 92 | 2.3 | 769 | 12,002 | 37.8% | 56.4% | |
| 59.78% | 92 | 1.3 | 768 | 12,186 | 51.5% | 64.4% | |
| 44.44% | 90 | 5.5 | 754 | 10,726 | 48.6% | 41.8% | |
| 54.55% | 88 | 6.3 | 768 | 11,482 | 48.6% | 58.8% | |
| 41.38% | 87 | 3.7 | 666 | 11,458 | 39.4% | 42.6% | |
| 58.33% | 72 | 1.1 | 658 | 12,756 | 45.0% | 63.5% | |
| 41.43% | 70 | 1.1 | 727 | 11,804 | 64.3% | 26.2% | |
| 50.00% | 70 | 4.3 | 700 | 10,780 | 48.4% | 51.3% | |
| 50.72% | 69 | 5.8 | 1,161 | 12,543 | 57.9% | 48.0% | |
| 53.85% | 65 | 5.4 | 775 | 12,598 | 58.3% | 51.2% | |
| 53.13% | 64 | 3.5 | 750 | 11,577 | 46.4% | 58.3% | |
| 45.45% | 55 | 1.3 | 643 | 11,553 | 61.1% | 37.8% | |
| 55.56% | 54 | 4.4 | 788 | 12,371 | 63.2% | 51.4% | |
| 49.06% | 53 | 1.5 | 738 | 12,521 | 52.9% | 47.2% | |
| 48.08% | 52 | 6.1 | 678 | 11,263 | 63.2% | 39.4% | |
| 55.77% | 52 | 1.9 | 728 | 11,537 | 56.5% | 55.2% | |
| 54.90% | 51 | 7.1 | 876 | 13,020 | 60.0% | 51.6% | |
| 58.82% | 51 | 1.1 | 701 | 12,390 | 60.0% | 58.1% | |
| 46.00% | 50 | 5.3 | 675 | 9,796 | 42.3% | 50.0% | |
| 38.78% | 49 | 1.5 | 754 | 12,566 | 43.8% | 36.4% | |
| 52.08% | 48 | 6.2 | 678 | 10,417 | 52.4% | 51.9% | |
| 70.83% | 48 | 1.8 | 794 | 12,184 | 68.8% | 71.9% | |
| 54.17% | 48 | 5.3 | 797 | 11,177 | 52.2% | 56.0% | |
| 52.08% | 48 | 1.3 | 728 | 11,720 | 44.4% | 56.7% | |
| 56.25% | 48 | 1.4 | 764 | 13,306 | 50.0% | 58.8% | |
| 54.35% | 46 | 4.8 | 764 | 11,189 | 44.4% | 60.7% | |
| 44.44% | 45 | 5.9 | 991 | 10,926 | 44.4% | 44.4% | |
| 53.49% | 43 | 6.3 | 691 | 11,431 | 69.2% | 46.7% | |
| 45.24% | 42 | 4.9 | 693 | 10,419 | 45.0% | 45.5% | |
| 48.78% | 41 | 5.2 | 722 | 11,678 | 47.4% | 50.0% | |
| 56.10% | 41 | 6.0 | 623 | 10,641 | 57.9% | 54.5% | |
| 50.00% | 40 | 1.8 | 735 | 12,182 | 52.4% | 47.4% | |
| 48.72% | 39 | 1.6 | 707 | 12,296 | 50.0% | 48.1% | |
| 56.41% | 39 | 4.8 | 759 | 11,779 | 45.5% | 60.7% | |
| 44.74% | 38 | 6.1 | 787 | 12,194 | 46.7% | 43.5% | |
| 63.16% | 38 | 5.2 | 659 | 11,336 | 68.4% | 57.9% | |
| 44.74% | 38 | 6.0 | 738 | 10,095 | 55.6% | 35.0% | |
| 70.27% | 37 | 6.3 | 783 | 11,208 | 80.0% | 63.6% | |
| 55.56% | 36 | 1.4 | 679 | 10,680 | 53.3% | 57.1% | |
| 44.44% | 36 | 1.2 | 696 | 11,017 | 35.7% | 50.0% | |
| 63.89% | 36 | 6.5 | 743 | 13,307 | 62.5% | 64.3% | |
| 54.29% | 35 | 3.5 | 700 | 11,754 | 53.3% | 55.0% | |
| 58.82% | 34 | 1.0 | 657 | 12,285 | 41.7% | 68.2% | |
| 48.48% | 33 | 7.0 | 723 | 12,128 | 63.6% | 40.9% | |
| 65.63% | 32 | 1.2 | 752 | 13,017 | 72.7% | 61.9% | |
| 62.50% | 32 | 6.7 | 781 | 10,493 | 72.2% | 50.0% | |
| 58.06% | 31 | 6.1 | 736 | 11,291 | 53.9% | 61.1% | |
| 70.97% | 31 | 4.9 | 938 | 11,950 | 61.5% | 77.8% | |
| 61.29% | 31 | 5.2 | 664 | 11,295 | 72.7% | 55.0% | |
| 48.39% | 31 | 6.0 | 827 | 11,013 | 46.1% | 50.0% | |
| 48.39% | 31 | 1.2 | 650 | 12,571 | 46.1% | 50.0% | |
| 53.33% | 30 | 1.9 | 749 | 12,300 | 63.6% | 47.4% | |
| 46.67% | 30 | 1.4 | 779 | 12,480 | 54.5% | 42.1% | |
| 64.29% | 28 | 2.6 | 745 | 13,856 | 66.7% | 62.5% | |
| 60.71% | 28 | 2.4 | 624 | 11,407 | 66.7% | 56.3% | |
| 53.57% | 28 | 6.6 | 792 | 12,087 | 44.4% | 57.9% | |
| 55.56% | 27 | 5.1 | 681 | 10,958 | 55.6% | 55.6% | |
| 59.26% | 27 | 6.1 | 783 | 12,314 | 81.8% | 43.8% | |
| 69.23% | 26 | 1.9 | 716 | 12,219 | 70.0% | 68.8% | |
| 73.08% | 26 | 5.5 | 811 | 12,338 | 85.7% | 68.4% | |
| 26.92% | 26 | 4.3 | 657 | 10,925 | 9.1% | 40.0% | |
| 66.67% | 24 | 1.1 | 530 | 11,739 | 66.7% | 66.7% | |
| 56.52% | 23 | 1.5 | 775 | 13,496 | 42.9% | 62.5% | |
| 69.57% | 23 | 6.1 | 769 | 10,225 | 66.7% | 71.4% | |
| 38.10% | 21 | 1.3 | 646 | 11,069 | 55.6% | 25.0% | |
| 55.56% | 18 | 5.1 | 731 | 13,110 | 75.0% | 50.0% | |
| 61.11% | 18 | 4.8 | 640 | 11,558 | 75.0% | 50.0% | |
| 43.75% | 16 | 1.5 | 667 | 12,788 | 0.0% | 53.9% | |
| 25.00% | 16 | 1.0 | 517 | 8,572 | 30.0% | 16.7% | |
| 60.00% | 15 | 2.9 | 666 | 11,244 | 57.1% | 62.5% | |
| 40.00% | 15 | 5.9 | 690 | 10,020 | 42.9% | 37.5% | |
| 57.14% | 14 | 6.1 | 929 | 13,866 | 100.0% | 53.9% | |
| 61.54% | 13 | 1.5 | 738 | 13,581 | 33.3% | 70.0% | |
| 30.77% | 13 | 6.2 | 690 | 12,712 | 33.3% | 30.0% | |
| 69.23% | 13 | 5.9 | 781 | 11,564 | 80.0% | 62.5% | |
| 66.67% | 12 | 2.0 | 816 | 13,327 | 50.0% | 75.0% | |
| 54.55% | 11 | 1.5 | 634 | 9,959 | 50.0% | 66.7% | |
| 70.00% | 10 | 6.4 | 1,000 | 12,296 | 80.0% | 60.0% | |
| 30.00% | 10 | 6.1 | 792 | 13,320 | 66.7% | 14.3% | |
| 50.00% | 10 | 6.6 | 636 | 11,620 | 50.0% | 50.0% | |
| 30.00% | 10 | 5.4 | 496 | 8,810 | 16.7% | 50.0% | |
| 66.67% | 9 | 1.7 | 750 | 13,786 | 100.0% | 57.1% | |
| 55.56% | 9 | 1.7 | 693 | 12,922 | 33.3% | 66.7% | |
| 42.86% | 7 | 6.2 | 667 | 12,724 | 100.0% | 33.3% | |
| 57.14% | 7 | 5.3 | 543 | 8,354 | 25.0% | 100.0% | |
| 14.29% | 7 | 6.3 | 532 | 10,148 | 0.0% | 33.3% | |
| 16.67% | 6 | 2.5 | 528 | 10,496 | 33.3% | 0.0% | |
| 66.67% | 6 | 6.0 | 711 | 10,821 | 100.0% | 60.0% | |
| 50.00% | 6 | 7.0 | 429 | 9,082 | 50.0% | 50.0% | |
| 40.00% | 5 | 6.1 | 803 | 9,814 | 50.0% | 33.3% | |
| 60.00% | 5 | 6.3 | 539 | 8,953 | 50.0% | 66.7% | |
| 60.00% | 5 | 4.7 | 580 | 11,407 | 0.0% | 60.0% | |
| 60.00% | 5 | 6.3 | 798 | 12,058 | 50.0% | 66.7% | |
| 40.00% | 5 | 3.6 | 759 | 14,285 | 0.0% | 40.0% | |
| 40.00% | 5 | 4.4 | 899 | 10,284 | 0.0% | 66.7% | |
| 60.00% | 5 | 6.4 | 814 | 16,147 | 100.0% | 50.0% | |
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Nasus vs Vayne - Frequently Asked Questions
How does Nasus do against Vayne in League of Legends?
Nasus wins the Nasus vs Vayne matchup with a 61.3% win rate compared to Vayne's 38.7%, a 22.6 percentage point difference. This data is based on 31 recent ranked games in patch 26.14.
How does Nasus do against Vayne in the early game?
In the early game, Nasus has the advantage against Vayne with a 72.7% win rate versus 27.3%. Nasus players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Nasus do against Vayne in the late game?
In the late game, Nasus takes over the Nasus vs Vayne matchup with a 55.0% win rate compared to 45.0%. Nasus scales better into team fights and objective contests after 25 minutes.
Who wins the Nasus vs Vayne matchup?
Nasus wins the matchup against Vayne with a 61.3% win rate in League of Legends patch 26.14. The 22.6 percentage point advantage means Nasus is significantly favored in this lane matchup based on 31 games analyzed.
What is the best Nasus build against Vayne?
The best Nasus build against Vayne includes Frozen Heart, Trinity Force, Thornmail with Ionian Boots of Lucidity. This build achieves a 33.3% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.
What are the best Nasus runes against Vayne?
The best Nasus runes against Vayne use the Precision primary tree with Resolve secondary. This rune setup achieves a 75.0% win rate in the Nasus vs Vayne matchup. See the full rune breakdown in the matchup comparison above.
Does Nasus counter Vayne?
Yes, Nasus has a favorable matchup against Vayne with a 61.3% win rate. Nasus strongly counters Vayne in lane based on current patch 26.14 data.
How do I play Nasus against Vayne?
When playing Nasus against Vayne, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.
