Nasus - League of Legends Champion
Win Rate
50.1%
Pick Rate
3.0%

Nasusvs Vayne

BFighterTank
Patch26.11
Matches776,441
LaneAll Lanes
TierAll Tiers
Last UpdatedJun 7, 2026
MethodologyData Methodology

Nasus vs Vayne is a moderate matchup in LoL patch 26.11. Vayne wins with a 51.9% win rate (+3.8%) over Nasus based on 52 games. Nasus wins the early laning phase while Vayne scales better into the late game. Below you'll find the best Nasus build, runes, laning stats, and strategies for the Nasus vs Vayne matchup.

MetaBot Desktop
Live In-Game Overlays
Join Our Discord
Bug reports, feature requests & developer chat
Join Discord

Nasus Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Nasus performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Nasus - 48.1% win rate in this matchup
Nasus
48.1% WR
VS
Vayne vs Nasus matchup - 51.9% win rate
Vayne
51.9% WR

Who Wins the Nasus vs Vayne Matchup?

Vayne wins the Nasus vs Vayne matchup
Winner
Vayne
Matches: 52
48.1%
Win Rate
51.9%
6.1
CS / min
6.0
636
DMG / min
913
11,710
Gold / game
11,592
466
Heal / min
228
1,444
DMG Mitigated / min
540
0.7
CC / min
0.4
51.9%
Early Game WR
48.1%
44.0%
Late Game WR
56.0%

Nasus vs Vayne Matchup Summary

The Nasus vs Vayne matchup is a moderate matchup in League of Legends ranked play. Based on 52 recent matches analyzed, Vayne wins with a 51.9% win rate compared to Nasus's 48.1%, giving Vayne a 3.8 percentage point advantage. Game phase dynamics play a critical role here: Nasus controls the early laning stage, but Vayne outscales as the game goes longer. The matchup shifts dramatically depending on game length — Nasus needs to press advantages before Vayne reaches their power spikes, while Vayne should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in sustain, where Nasus leads by 1,142 HP/min — a difference that heavily influences the outcome of trades and skirmishes. While Vayne is slightly favored, Nasus can absolutely win this lane through smart trading patterns and wave management. Focus on playing around your cooldowns, conceding CS only when necessary, and capitalizing on Vayne's mistakes. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Nasus vs Vayne Laning Phase Breakdown

Nasus wins the laning phase against Vayne in League of Legends

Nasus is favored during the laning phase against Vayne, winning 4 out of 5 key stat categories. Nasus holds advantages in farming, gold income, crowd control and sustain, making them the stronger laner in this matchup.

Farming
6.1Nasus
6.0Vayne
Nasus and Vayne farm at nearly identical rates in this matchup, with only a 0.1 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
636Nasus
913Vayne
Vayne heavily out-damages Nasus by 276 DMG/min, dominating both short trades and all-in fights. Nasus should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Vayne's sustained damage advantage take over.
Economy
11,710Nasus
11,592Vayne
Nasus and Vayne generate nearly equal gold per game, with just a 118 gold difference. Neither champion has a clear economic advantage, so gold leads will depend on individual play quality, kill participation, and objective contributions.
Utility
0.7Nasus
0.4Vayne
Nasus provides 0.3 seconds more crowd control per minute than Vayne, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Nasus coordinate with their jungler and control the pace of skirmishes.
Sustain
1,910Nasus
769Vayne
Nasus vastly out-sustains Vayne, healing and mitigating 1,142 more damage per minute. This massive durability gap means Nasus can absorb significant punishment and remain in lane while Vayne is forced to recall. Building grievous wounds early is essential for Vayne, and focusing on burst trade patterns rather than sustained fights is critical.

Best Nasus Build Against Vayne

Plated Steelcaps is the optimal boots choice against Vayne, providing the mobility and stats Nasus needs most in this matchup. The top-performing core items for Nasus against Vayne are Frozen Heart, Trinity Force and Thornmail. This combination gives Nasus an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 60.0% win rate across 5 games — well above average and making it the top item path against Vayne. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Nasus vs Vayne matchup.

Early Game vs Late Game

Early Game
Nasus
51.9%
+3.7% advantage
Nasus early game win rateNasus51.9%
Vayne early game win rateVayne48.1%
Late Game
Vayne
56.0%
+12.0% advantage
Nasus late game win rateNasus44.0%
Vayne late game win rateVayne56.0%

During the early laning phase (first 15 minutes), Nasus has a meaningful 51.9% win rate, outperforming Vayne by 3.7 percentage points. Nasus players should look to press this advantage through aggressive trades, wave priority, and early jungle coordination.

Vayne is far superior in the late game (25+ minutes), boasting a 56.0% win rate — 12.0 points above Nasus. Extended games heavily favor Vayne, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Nasus must aggressively press their early advantage and close out the game before Vayne reaches their scaling breakpoints. If Vayne survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Nasus Runes Against Vayne

Sorcery rune tree - Nasus primary runes vs VayneSorcery
Stormraider's Surge - best Nasus rune vs VayneManaflow Band - best Nasus rune vs VayneTranscendence - best Nasus rune vs VayneScorch - best Nasus rune vs Vayne
Precision rune tree - Nasus secondary runes vs VaynePrecision
Legend: Haste - best Nasus rune vs VayneLast Stand - best Nasus rune vs Vayne
100.0% WR

The Sorcery and Precision rune setup gives Nasus the best tools to compete against Vayne in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Nasus matchup data for League of Legends patch 26.11. The table below shows Nasus's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Nasus build, runes, laning stats, and early vs late game analysis for that specific matchup.

Nasus matchup win rates and stats in League of Legends patch 26.11
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
45.83%2166.371911,29038.5%51.2%
40.11%1825.964211,61746.4%36.3%
57.76%1615.875411,79154.8%59.6%
48.18%1376.085111,61552.6%45.0%
53.33%1355.770911,46456.4%51.3%
48.06%1296.471912,08350.0%46.8%
48.00%1256.472511,58250.9%45.8%
49.14%1166.170711,74940.8%55.2%
45.10%1026.582511,87636.8%50.0%
43.16%955.776810,82236.2%50.0%
48.39%935.172811,18942.9%52.9%
45.98%876.482311,80741.0%50.0%
48.24%855.776211,93455.2%44.6%
38.55%835.978911,12136.1%40.4%
53.09%816.11,12811,53845.2%61.5%
48.65%742.669711,51847.2%50.0%
54.79%736.583711,92661.5%51.1%
54.29%707.181012,80736.7%67.5%
42.03%696.262310,95945.5%38.9%
36.92%656.477711,16555.6%23.7%
49.23%655.576211,50350.0%48.6%
50.77%652.072512,62550.0%51.1%
41.54%655.986912,54530.8%48.7%
64.62%656.778813,30575.0%58.5%
55.56%636.575011,42856.7%54.5%
56.45%626.370412,24847.8%61.5%
54.24%596.572211,84256.5%52.8%
55.17%583.781612,24866.7%42.9%
51.79%566.166111,06848.1%55.2%
52.73%556.578113,08070.0%42.9%
59.26%543.377512,12864.0%55.2%
55.56%546.072412,31855.0%55.9%
44.44%545.578110,45140.0%48.3%
53.70%542.370712,30538.1%63.6%
54.72%536.366512,45852.9%55.6%
48.08%526.163611,71051.9%44.0%
66.67%512.176713,43763.6%69.0%
35.42%485.680310,25431.8%38.5%
45.83%485.477610,58744.0%47.8%
48.94%476.580712,31242.1%53.6%
67.44%431.477212,94270.6%65.4%
59.52%426.477612,34952.9%64.0%
52.38%421.163412,53350.0%53.3%
59.52%423.966412,61560.0%59.3%
31.71%415.388612,13642.9%25.9%
51.22%416.073211,68762.5%44.0%
52.50%402.379912,92141.2%60.9%
50.00%401.870612,59650.0%50.0%
61.54%395.873012,35766.7%59.3%
61.54%396.271011,31247.6%77.8%
63.64%336.172813,15360.0%65.2%
56.25%324.171713,26554.5%57.1%
58.06%313.778911,79243.8%73.3%
53.33%303.765012,29442.9%62.5%
58.62%296.677210,66941.7%70.6%
50.00%281.974913,92257.1%47.6%
46.43%286.681210,95661.5%33.3%
77.78%276.081112,165100.0%64.7%
51.85%271.675513,24550.0%52.6%
53.85%261.977212,45750.0%57.1%
50.00%246.870711,74272.7%30.8%
52.17%233.574112,32541.7%63.6%
65.22%234.885312,35845.5%83.3%
59.09%226.468212,36150.0%64.3%
63.64%226.868110,18566.7%60.0%
47.62%216.575311,16955.6%41.7%
40.00%205.664011,22750.0%30.0%
40.00%202.066912,70242.9%38.5%
30.00%201.277412,34618.2%44.4%
42.11%192.566611,06550.0%33.3%
50.00%182.182112,97837.5%60.0%
50.00%186.78299,71750.0%50.0%
55.56%183.280011,99450.0%60.0%
23.53%176.161411,48122.2%25.0%
64.71%171.981713,17550.0%72.7%
25.00%161.972713,55750.0%10.0%
37.50%167.277513,20262.5%12.5%
56.25%162.972913,07950.0%60.0%
31.25%161.671212,10014.3%44.4%
50.00%166.773311,32140.0%54.5%
50.00%165.969113,52366.7%40.0%
43.75%166.692810,35733.3%57.1%
46.67%155.762712,59450.0%44.4%
46.67%154.91,02312,14066.7%33.3%
46.67%151.978312,81733.3%55.6%
66.67%155.387414,64033.3%88.9%
57.14%146.664812,21857.1%57.1%
50.00%141.168111,34242.9%57.1%
50.00%142.759910,57044.4%60.0%
35.71%141.860811,85633.3%40.0%
53.85%136.369711,11742.9%66.7%
61.54%135.971612,30450.0%71.4%
41.67%126.182610,28442.9%40.0%
58.33%124.41,04013,86966.7%55.6%
63.64%116.060613,05366.7%60.0%
60.00%105.773710,57340.0%80.0%
55.56%96.765413,240100.0%42.9%
44.44%94.363811,39433.3%50.0%
55.56%96.774110,79660.0%50.0%
66.67%95.571313,79666.7%66.7%
44.44%95.171812,98066.7%33.3%
50.00%83.04439,95666.7%40.0%
50.00%85.880611,35460.0%33.3%
25.00%86.261110,0510.0%40.0%
25.00%86.555711,10733.3%20.0%
75.00%81.280913,89350.0%83.3%
14.29%76.34829,3850.0%33.3%
28.57%72.966711,98666.7%0.0%
28.57%70.84378,99420.0%50.0%
42.86%71.157511,481100.0%20.0%
66.67%61.686914,6380.0%66.7%
66.67%67.388012,43750.0%75.0%
0.00%63.261210,3180.0%0.0%
50.00%66.175813,39333.3%66.7%
50.00%66.782311,08333.3%66.7%
40.00%54.777212,76750.0%33.3%
40.00%54.365113,4990.0%66.7%
20.00%55.861212,870100.0%0.0%
80.00%56.376814,17166.7%100.0%
40.00%52.663512,3990.0%66.7%
60.00%55.26417,98766.7%50.0%

Get the MetaBot Desktop App

Level up your gameplay with real-time overlays, automatic game detection, and instant stats — all on your desktop.

In-game overlaysAuto game detectionMulti-game supportPersonal dashboard
Download NowFree download
🔍

Help us maintain accuracy! If you notice incorrect stats, missing data, or any issues, your feedback directly improves the quality of our data for the entire community.

Report an Issue

Nasus vs Vayne - Frequently Asked Questions

How does Nasus do against Vayne in League of Legends?

Vayne wins the Nasus vs Vayne matchup with a 51.9% win rate compared to Nasus's 48.1%, a 3.8 percentage point difference. This data is based on 52 recent ranked games in patch 26.11.

How does Nasus do against Vayne in the early game?

In the early game, Nasus has the advantage against Vayne with a 51.9% win rate versus 48.1%. Nasus players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Nasus do against Vayne in the late game?

In the late game, Vayne takes over the Nasus vs Vayne matchup with a 56.0% win rate compared to 44.0%. Vayne scales better into team fights and objective contests after 25 minutes.

Who wins the Nasus vs Vayne matchup?

Vayne wins the matchup against Nasus with a 51.9% win rate in League of Legends patch 26.11. The 3.8 percentage point advantage means Vayne is moderately favored in this lane matchup based on 52 games analyzed.

What is the best Nasus build against Vayne?

The best Nasus build against Vayne includes Frozen Heart, Trinity Force, Thornmail with Plated Steelcaps. This build achieves a 60.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Nasus runes against Vayne?

The best Nasus runes against Vayne use the Sorcery primary tree with Precision secondary. This rune setup achieves a 100.0% win rate in the Nasus vs Vayne matchup. See the full rune breakdown in the matchup comparison above.

Does Nasus counter Vayne?

No, Nasus struggles against Vayne with only a 48.1% win rate. Vayne has the advantage in this matchup. Nasus players should focus on safe farming and avoiding extended trades to minimize Vayne's lead.

How do I play Nasus against Vayne?

When playing Nasus against Vayne, play cautiously and avoid Vayne's power spikes. Look for jungle assistance and team-dependent plays since Vayne has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.