Vaynevs Nasus
Vayne vs Nasus is a decisive matchup in LoL patch 26.14. Nasus wins with a 61.3% win rate (+22.6%) over Vayne based on 31 games. Nasus holds the advantage in both the early and late game. Below you'll find the best Vayne build, runes, laning stats, and strategies for the Vayne vs Nasus matchup.
Vayne Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Vayne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Vayne vs Nasus Matchup?
Vayne vs Nasus Matchup Summary
The Vayne vs Nasus matchup is a decisive matchup in League of Legends ranked play. Based on 31 recent matches analyzed, Nasus wins with a 61.3% win rate compared to Vayne's 38.7%, giving Nasus a 22.6 percentage point advantage. Nasus dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Vayne players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Nasus leads by 1,174 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Nasus has a strong advantage in this matchup. Vayne players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Nasus overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Vayne vs Nasus Laning Phase Breakdown
Vayne is favored during the laning phase against Nasus, winning 3 out of 5 key stat categories. Vayne holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.
Best Vayne Build Against Nasus
Berserker's Greaves is the optimal boots choice against Nasus, providing the mobility and stats Vayne needs most in this matchup. The top-performing core items for Vayne against Nasus are Kraken Slayer, Blade of The Ruined King and Guinsoo's Rageblade. This combination gives Vayne an effective balance of damage, survivability, and utility for the matchup. This build achieves a solid 50.0% win rate across 4 games, proving it to be a reliable item path when facing Nasus. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Vayne vs Nasus matchup.
Early Game vs Late Game
Vayne27.3%
Nasus72.7%Vayne45.0%Nasus55.0%Nasus dominates the early game (first 15 minutes) with a commanding 72.7% win rate — a 45.5 percentage point lead over Vayne. This lopsided early game means Nasus can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Nasus is far superior in the late game (25+ minutes), boasting a 55.0% win rate — 10.0 points above Vayne. Extended games heavily favor Nasus, whose kit and scaling make them a dominant force in team fights and objective control.
Nasus holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Vayne players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.
Best Vayne Runes Against Nasus
Precision
Resolve
The Precision and Resolve rune setup gives Vayne the best tools to compete against Nasus in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.
Vayne matchup data for League of Legends patch 26.14. The table below shows Vayne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vayne build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 48.56% | 348 | 5.8 | 847 | 12,979 | 44.1% | 50.9% | |
| 53.42% | 307 | 5.9 | 839 | 12,940 | 48.8% | 56.6% | |
| 48.20% | 278 | 6.1 | 836 | 13,470 | 41.3% | 51.6% | |
| 47.74% | 243 | 6.2 | 860 | 12,610 | 47.6% | 47.9% | |
| 53.08% | 211 | 6.3 | 878 | 12,621 | 43.0% | 61.0% | |
| 41.53% | 183 | 6.1 | 773 | 12,603 | 38.8% | 43.1% | |
| 52.78% | 144 | 6.1 | 791 | 12,829 | 55.8% | 51.1% | |
| 51.91% | 131 | 6.4 | 881 | 14,083 | 40.9% | 57.5% | |
| 41.41% | 128 | 6.1 | 892 | 12,802 | 38.3% | 43.2% | |
| 49.00% | 100 | 6.3 | 952 | 13,528 | 45.7% | 50.8% | |
| 42.86% | 98 | 6.0 | 825 | 13,131 | 40.0% | 44.1% | |
| 52.75% | 91 | 6.2 | 890 | 12,275 | 55.1% | 50.0% | |
| 50.00% | 88 | 5.7 | 727 | 12,174 | 43.8% | 53.6% | |
| 51.81% | 83 | 6.1 | 910 | 11,362 | 54.5% | 50.0% | |
| 47.50% | 80 | 6.1 | 820 | 12,475 | 45.7% | 48.9% | |
| 60.00% | 65 | 6.0 | 974 | 12,774 | 68.2% | 55.8% | |
| 50.00% | 64 | 6.0 | 847 | 11,777 | 46.1% | 52.6% | |
| 62.50% | 64 | 6.1 | 899 | 12,623 | 66.7% | 58.8% | |
| 33.33% | 60 | 5.7 | 698 | 10,500 | 28.6% | 37.5% | |
| 64.91% | 57 | 6.1 | 1,042 | 12,267 | 60.0% | 68.8% | |
| 50.88% | 57 | 6.1 | 787 | 12,253 | 54.8% | 46.1% | |
| 53.57% | 56 | 5.8 | 725 | 12,485 | 43.5% | 60.6% | |
| 47.17% | 53 | 6.4 | 721 | 12,526 | 33.3% | 58.6% | |
| 45.28% | 53 | 5.7 | 745 | 11,425 | 48.1% | 42.3% | |
| 40.38% | 52 | 6.0 | 807 | 12,805 | 42.9% | 38.7% | |
| 52.00% | 50 | 5.6 | 757 | 10,827 | 71.4% | 37.9% | |
| 24.00% | 50 | 5.5 | 593 | 10,367 | 10.5% | 32.3% | |
| 50.00% | 48 | 6.3 | 804 | 12,299 | 37.5% | 62.5% | |
| 43.48% | 46 | 5.9 | 831 | 13,246 | 40.0% | 46.1% | |
| 64.44% | 45 | 6.6 | 1,356 | 13,355 | 52.9% | 71.4% | |
| 44.19% | 43 | 6.5 | 783 | 12,296 | 42.9% | 45.5% | |
| 48.78% | 41 | 6.2 | 879 | 13,464 | 28.6% | 59.3% | |
| 52.94% | 34 | 6.7 | 896 | 13,048 | 50.0% | 55.6% | |
| 63.64% | 33 | 6.5 | 1,116 | 12,112 | 53.3% | 72.2% | |
| 62.50% | 32 | 6.3 | 819 | 12,631 | 45.5% | 71.4% | |
| 59.38% | 32 | 6.1 | 854 | 12,126 | 88.9% | 47.8% | |
| 38.71% | 31 | 5.7 | 1,025 | 11,464 | 27.3% | 45.0% | |
| 54.84% | 31 | 5.8 | 820 | 11,578 | 20.0% | 71.4% | |
| 67.74% | 31 | 6.0 | 1,055 | 12,463 | 54.5% | 75.0% | |
| 43.33% | 30 | 6.2 | 879 | 12,495 | 36.4% | 47.4% | |
| 53.33% | 30 | 6.5 | 1,296 | 14,350 | 44.4% | 57.1% | |
| 42.86% | 28 | 5.9 | 832 | 12,552 | 36.4% | 47.1% | |
| 66.67% | 27 | 6.3 | 893 | 10,712 | 69.2% | 64.3% | |
| 62.96% | 27 | 6.3 | 1,010 | 10,804 | 57.1% | 69.2% | |
| 51.85% | 27 | 6.6 | 827 | 11,719 | 60.0% | 47.1% | |
| 40.00% | 25 | 5.9 | 1,076 | 12,666 | 55.6% | 31.3% | |
| 66.67% | 24 | 6.3 | 851 | 11,368 | 75.0% | 58.3% | |
| 41.67% | 24 | 6.5 | 982 | 11,958 | 53.9% | 27.3% | |
| 39.13% | 23 | 5.3 | 808 | 11,110 | 11.1% | 57.1% | |
| 43.48% | 23 | 5.9 | 903 | 12,039 | 40.0% | 44.4% | |
| 52.17% | 23 | 6.3 | 716 | 12,158 | 50.0% | 53.3% | |
| 50.00% | 22 | 6.3 | 786 | 12,373 | 50.0% | 50.0% | |
| 50.00% | 22 | 6.3 | 877 | 11,269 | 33.3% | 61.5% | |
| 54.55% | 22 | 6.1 | 944 | 13,476 | 50.0% | 56.3% | |
| 50.00% | 22 | 5.7 | 857 | 10,867 | 66.7% | 38.5% | |
| 61.90% | 21 | 5.7 | 807 | 11,322 | 55.6% | 66.7% | |
| 38.10% | 21 | 6.1 | 885 | 12,478 | 66.7% | 26.7% | |
| 47.62% | 21 | 6.3 | 794 | 14,046 | 33.3% | 50.0% | |
| 40.00% | 20 | 6.1 | 896 | 12,759 | 40.0% | 40.0% | |
| 68.42% | 19 | 6.1 | 951 | 10,335 | 75.0% | 63.6% | |
| 57.89% | 19 | 6.3 | 813 | 12,245 | 50.0% | 63.6% | |
| 50.00% | 18 | 5.8 | 938 | 11,873 | 55.6% | 44.4% | |
| 70.59% | 17 | 6.4 | 1,041 | 13,115 | 80.0% | 66.7% | |
| 56.25% | 16 | 6.5 | 811 | 14,119 | 50.0% | 58.3% | |
| 43.75% | 16 | 5.6 | 733 | 11,696 | 28.6% | 55.6% | |
| 31.25% | 16 | 6.0 | 738 | 11,878 | 40.0% | 27.3% | |
| 62.50% | 16 | 6.2 | 946 | 12,972 | 50.0% | 70.0% | |
| 46.67% | 15 | 6.0 | 661 | 9,616 | 55.6% | 33.3% | |
| 66.67% | 15 | 6.2 | 938 | 14,618 | 25.0% | 81.8% | |
| 78.57% | 14 | 6.8 | 918 | 15,770 | 100.0% | 70.0% | |
| 35.71% | 14 | 6.2 | 906 | 9,942 | 33.3% | 37.5% | |
| 71.43% | 14 | 6.4 | 846 | 13,112 | 42.9% | 100.0% | |
| 64.29% | 14 | 6.1 | 1,149 | 12,061 | 57.1% | 71.4% | |
| 53.85% | 13 | 5.9 | 810 | 13,109 | 33.3% | 60.0% | |
| 53.85% | 13 | 5.4 | 1,017 | 13,231 | 50.0% | 57.1% | |
| 53.85% | 13 | 5.8 | 757 | 10,865 | 75.0% | 20.0% | |
| 50.00% | 12 | 6.3 | 894 | 13,153 | 25.0% | 62.5% | |
| 58.33% | 12 | 6.5 | 863 | 10,158 | 33.3% | 83.3% | |
| 41.67% | 12 | 4.4 | 890 | 10,679 | 50.0% | 25.0% | |
| 54.55% | 11 | 5.7 | 764 | 12,344 | 33.3% | 62.5% | |
| 50.00% | 10 | 6.4 | 838 | 12,063 | 66.7% | 42.9% | |
| 80.00% | 10 | 6.0 | 847 | 12,029 | 100.0% | 66.7% | |
| 33.33% | 9 | 5.0 | 723 | 12,686 | 0.0% | 50.0% | |
| 22.22% | 9 | 4.0 | 782 | 13,444 | 0.0% | 33.3% | |
| 66.67% | 9 | 4.3 | 882 | 14,962 | 100.0% | 62.5% | |
| 77.78% | 9 | 5.5 | 792 | 15,017 | 100.0% | 71.4% | |
| 25.00% | 8 | 6.4 | 866 | 11,042 | 50.0% | 0.0% | |
| 37.50% | 8 | 4.5 | 780 | 11,842 | 50.0% | 33.3% | |
| 12.50% | 8 | 4.4 | 823 | 11,955 | 25.0% | 0.0% | |
| 71.43% | 7 | 6.4 | 795 | 13,702 | 50.0% | 80.0% | |
| 42.86% | 7 | 4.8 | 522 | 10,756 | 33.3% | 50.0% | |
| 33.33% | 6 | 6.0 | 825 | 14,164 | 0.0% | 40.0% | |
| 50.00% | 6 | 3.2 | 462 | 10,339 | 66.7% | 33.3% | |
| 16.67% | 6 | 5.1 | 933 | 11,156 | 33.3% | 0.0% | |
| 50.00% | 6 | 4.0 | 739 | 8,973 | 50.0% | 50.0% | |
| 50.00% | 6 | 3.1 | 630 | 7,383 | 50.0% | 50.0% | |
| 83.33% | 6 | 5.5 | 718 | 14,890 | 100.0% | 80.0% | |
| 66.67% | 6 | 5.9 | 979 | 16,504 | 0.0% | 66.7% | |
| 16.67% | 6 | 4.7 | 846 | 11,283 | 0.0% | 25.0% | |
| 40.00% | 5 | 0.7 | 512 | 11,183 | 33.3% | 50.0% | |
| 0.00% | 5 | 5.7 | 822 | 10,600 | 0.0% | 0.0% | |
| 60.00% | 5 | 6.9 | 792 | 12,100 | 50.0% | 66.7% | |
| 60.00% | 5 | 4.2 | 988 | 15,386 | 0.0% | 60.0% | |
| 40.00% | 5 | 4.5 | 714 | 9,282 | 66.7% | 0.0% | |
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Vayne vs Nasus - Frequently Asked Questions
How does Vayne do against Nasus in League of Legends?
Nasus wins the Vayne vs Nasus matchup with a 61.3% win rate compared to Vayne's 38.7%, a 22.6 percentage point difference. This data is based on 31 recent ranked games in patch 26.14.
How does Vayne do against Nasus in the early game?
In the early game, Nasus has the advantage against Vayne with a 72.7% win rate versus 27.3%. Nasus players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Vayne do against Nasus in the late game?
In the late game, Nasus takes over the Vayne vs Nasus matchup with a 55.0% win rate compared to 45.0%. Nasus scales better into team fights and objective contests after 25 minutes.
Who wins the Vayne vs Nasus matchup?
Nasus wins the matchup against Vayne with a 61.3% win rate in League of Legends patch 26.14. The 22.6 percentage point advantage means Nasus is significantly favored in this lane matchup based on 31 games analyzed.
What is the best Vayne build against Nasus?
The best Vayne build against Nasus includes Kraken Slayer, Blade of The Ruined King, Guinsoo's Rageblade with Berserker's Greaves. This build achieves a 50.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.
What are the best Vayne runes against Nasus?
The best Vayne runes against Nasus use the Precision primary tree with Resolve secondary. This rune setup achieves a 58.3% win rate in the Vayne vs Nasus matchup. See the full rune breakdown in the matchup comparison above.
Does Vayne counter Nasus?
No, Vayne struggles against Nasus with only a 38.7% win rate. Nasus has the advantage in this matchup. Vayne players should focus on safe farming and avoiding extended trades to minimize Nasus's lead.
How do I play Vayne against Nasus?
When playing Vayne against Nasus, play cautiously and avoid Nasus's power spikes. Look for jungle assistance and team-dependent plays since Nasus has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.