Pantheonvs Vayne
Pantheon vs Vayne is a decisive matchup in LoL patch 26.4. Pantheon wins with a 53.9% win rate (+7.7%) over Vayne based on 26 games. Vayne wins the early laning phase while Pantheon scales better into the late game. Below you'll find the best Pantheon build, runes, laning stats, and strategies for the Pantheon vs Vayne matchup.
Pantheon Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Pantheon performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Vayne(53.9%)Who Wins the Pantheon vs Vayne Matchup?
Pantheon vs Vayne Matchup Summary
The Pantheon vs Vayne matchup is a decisive matchup in League of Legends ranked play. Based on 26 recent matches analyzed, Pantheon wins with a 53.9% win rate compared to Vayne's 46.1%, giving Pantheon a 7.7 percentage point advantage. Game phase dynamics play a critical role here: Vayne controls the early laning stage, but Pantheon outscales as the game goes longer. The matchup shifts dramatically depending on game length — Vayne needs to press advantages before Pantheon reaches their power spikes, while Pantheon should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Pantheon leads by 0.5s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Pantheon players can confidently pick into Vayne and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Vayne away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Pantheon vs Vayne Laning Phase Breakdown
Vayne is favored during the laning phase against Pantheon, winning 3 out of 5 key stat categories. Vayne holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.
Best Pantheon Build Against Vayne
Ionian Boots of Lucidity is the optimal boots choice against Vayne, providing the mobility and stats Pantheon needs most in this matchup. The top-performing core items for Pantheon against Vayne are Eclipse, Sundered Sky and Death's Dance. This combination gives Pantheon an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 2 games — well above average and making it the top item path against Vayne. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Pantheon vs Vayne matchup.
Early Game vs Late Game
Pantheon30.0%Vayne70.0%Pantheon68.8%Vayne31.3%Vayne dominates the early game (first 15 minutes) with a commanding 70.0% win rate — a 40.0 percentage point lead over Pantheon. This lopsided early game means Vayne can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Pantheon is far superior in the late game (25+ minutes), boasting a 68.8% win rate — 37.5 points above Vayne. Extended games heavily favor Pantheon, whose kit and scaling make them a dominant force in team fights and objective control.
This matchup features a dramatic power shift: Vayne must aggressively press their early advantage and close out the game before Pantheon reaches their scaling breakpoints. If Pantheon survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.
Best Pantheon Runes Against Vayne
Precision
Sorcery
Running Precision primary with Sorcery secondary allows Pantheon to press their advantage against Vayne, amplifying the strengths that make this a favorable matchup.
Pantheon matchup data for League of Legends patch 26.4. The table below shows Pantheon's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Pantheon build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 47.46% | 237 | 2.1 | 678 | 10,922 | 41.8% | 51.5% | |
| 47.55% | 207 | 1.5 | 679 | 10,661 | 43.2% | 50.9% | |
| 48.91% | 184 | 1.5 | 654 | 10,127 | 44.3% | 52.4% | |
| 54.44% | 169 | 1.7 | 705 | 10,594 | 59.7% | 51.0% | |
| 41.77% | 159 | 1.6 | 701 | 11,185 | 43.9% | 40.2% | |
| 56.29% | 151 | 5.8 | 949 | 12,360 | 63.5% | 49.4% | |
| 49.65% | 141 | 1.7 | 686 | 10,311 | 47.8% | 51.4% | |
| 52.31% | 131 | 1.6 | 712 | 11,197 | 56.8% | 50.0% | |
| 49.59% | 123 | 5.6 | 974 | 12,083 | 44.6% | 53.7% | |
| 41.53% | 119 | 2.0 | 768 | 11,484 | 46.7% | 38.4% | |
| 44.74% | 114 | 1.5 | 629 | 10,023 | 59.3% | 31.7% | |
| 49.02% | 102 | 1.5 | 704 | 10,430 | 52.1% | 46.3% | |
| 48.00% | 101 | 1.5 | 619 | 10,424 | 51.1% | 45.3% | |
| 49.49% | 100 | 1.5 | 708 | 10,562 | 53.5% | 46.4% | |
| 50.52% | 97 | 1.5 | 635 | 10,156 | 51.1% | 50.0% | |
| 56.70% | 97 | 4.9 | 913 | 12,528 | 47.5% | 63.2% | |
| 55.21% | 96 | 3.6 | 758 | 11,665 | 61.4% | 50.0% | |
| 52.08% | 96 | 6.0 | 906 | 12,465 | 54.3% | 50.8% | |
| 59.14% | 93 | 1.5 | 653 | 10,059 | 69.2% | 46.3% | |
| 47.31% | 93 | 3.0 | 865 | 10,272 | 38.1% | 54.9% | |
| 47.31% | 93 | 4.7 | 856 | 11,242 | 50.0% | 45.3% | |
| 56.18% | 89 | 1.5 | 633 | 9,906 | 60.5% | 52.2% | |
| 44.05% | 85 | 1.6 | 688 | 9,811 | 52.0% | 32.4% | |
| 39.76% | 84 | 2.1 | 763 | 10,716 | 43.2% | 37.0% | |
| 52.38% | 84 | 5.4 | 825 | 11,358 | 47.7% | 57.5% | |
| 47.62% | 84 | 1.5 | 698 | 11,001 | 50.0% | 46.3% | |
| 46.99% | 83 | 3.9 | 915 | 12,012 | 58.3% | 38.3% | |
| 55.56% | 82 | 1.0 | 765 | 13,315 | 68.8% | 46.9% | |
| 54.43% | 80 | 5.6 | 980 | 11,900 | 59.5% | 50.0% | |
| 40.51% | 79 | 4.2 | 1,076 | 11,312 | 42.9% | 38.6% | |
| 59.49% | 79 | 5.5 | 895 | 12,033 | 61.4% | 57.1% | |
| 50.65% | 77 | 5.0 | 894 | 11,797 | 42.9% | 60.0% | |
| 50.68% | 73 | 1.6 | 630 | 10,168 | 48.6% | 52.8% | |
| 50.70% | 72 | 2.5 | 850 | 12,860 | 55.6% | 45.7% | |
| 40.58% | 71 | 2.0 | 690 | 10,796 | 48.6% | 32.4% | |
| 50.72% | 71 | 1.5 | 748 | 10,620 | 45.2% | 55.3% | |
| 47.06% | 70 | 1.6 | 766 | 10,763 | 58.3% | 34.4% | |
| 49.28% | 69 | 5.1 | 952 | 11,072 | 51.4% | 46.9% | |
| 45.16% | 62 | 2.5 | 688 | 10,960 | 40.0% | 48.6% | |
| 45.16% | 62 | 5.8 | 883 | 11,603 | 56.7% | 34.4% | |
| 31.67% | 62 | 1.7 | 714 | 10,361 | 36.7% | 26.7% | |
| 52.46% | 61 | 4.2 | 829 | 11,734 | 58.6% | 46.9% | |
| 36.07% | 61 | 4.1 | 720 | 10,964 | 20.7% | 50.0% | |
| 47.54% | 61 | 4.4 | 824 | 11,822 | 33.3% | 61.3% | |
| 44.07% | 60 | 5.9 | 810 | 11,916 | 37.0% | 50.0% | |
| 50.00% | 60 | 3.4 | 747 | 10,667 | 50.0% | 50.0% | |
| 40.68% | 59 | 4.8 | 939 | 11,650 | 33.3% | 45.7% | |
| 50.00% | 58 | 5.4 | 1,082 | 11,853 | 50.0% | 50.0% | |
| 50.88% | 58 | 3.3 | 826 | 12,939 | 39.1% | 58.8% | |
| 37.93% | 58 | 4.5 | 803 | 11,602 | 37.0% | 38.7% | |
| 55.17% | 58 | 2.6 | 736 | 11,742 | 62.5% | 50.0% | |
| 49.09% | 57 | 3.1 | 760 | 11,846 | 46.7% | 52.0% | |
| 57.89% | 57 | 5.0 | 847 | 11,018 | 53.1% | 64.0% | |
| 50.00% | 57 | 5.6 | 863 | 12,115 | 62.5% | 40.6% | |
| 45.45% | 55 | 4.0 | 799 | 11,510 | 42.3% | 48.3% | |
| 45.45% | 55 | 1.4 | 700 | 10,097 | 51.6% | 37.5% | |
| 50.00% | 54 | 1.2 | 739 | 12,787 | 37.5% | 60.0% | |
| 40.38% | 53 | 2.0 | 836 | 11,895 | 50.0% | 36.1% | |
| 46.15% | 52 | 1.4 | 652 | 10,530 | 36.4% | 53.3% | |
| 39.22% | 51 | 6.0 | 892 | 10,307 | 30.4% | 46.4% | |
| 50.98% | 51 | 5.7 | 846 | 11,535 | 48.1% | 54.2% | |
| 49.02% | 51 | 1.8 | 717 | 10,872 | 52.6% | 46.9% | |
| 53.06% | 51 | 5.4 | 888 | 10,885 | 45.8% | 60.0% | |
| 46.94% | 49 | 4.9 | 952 | 11,931 | 47.6% | 46.4% | |
| 62.50% | 48 | 3.7 | 982 | 12,352 | 36.8% | 79.3% | |
| 60.42% | 48 | 5.0 | 984 | 13,020 | 46.7% | 66.7% | |
| 52.08% | 48 | 5.6 | 886 | 11,976 | 36.8% | 62.1% | |
| 40.43% | 47 | 5.5 | 779 | 10,933 | 47.1% | 36.7% | |
| 39.13% | 46 | 5.0 | 836 | 12,264 | 40.0% | 38.5% | |
| 44.44% | 45 | 1.4 | 564 | 8,865 | 43.3% | 46.7% | |
| 39.53% | 43 | 1.2 | 688 | 12,054 | 25.0% | 45.2% | |
| 64.29% | 43 | 3.1 | 776 | 11,919 | 69.6% | 57.9% | |
| 52.38% | 42 | 5.9 | 960 | 11,669 | 42.1% | 60.9% | |
| 30.95% | 42 | 5.3 | 854 | 11,131 | 40.0% | 22.7% | |
| 57.14% | 42 | 1.3 | 711 | 12,003 | 40.0% | 66.7% | |
| 48.78% | 41 | 5.1 | 840 | 11,823 | 27.8% | 65.2% | |
| 52.50% | 40 | 1.3 | 739 | 13,780 | 58.3% | 50.0% | |
| 47.50% | 40 | 6.0 | 1,047 | 12,083 | 45.5% | 50.0% | |
| 48.72% | 39 | 1.6 | 685 | 10,022 | 45.0% | 52.6% | |
| 43.59% | 39 | 6.3 | 882 | 11,868 | 45.5% | 41.2% | |
| 44.74% | 38 | 1.6 | 806 | 12,144 | 50.0% | 38.9% | |
| 39.47% | 38 | 5.4 | 893 | 12,262 | 56.3% | 27.3% | |
| 47.22% | 36 | 2.0 | 762 | 10,901 | 46.7% | 47.6% | |
| 55.56% | 36 | 4.3 | 811 | 10,831 | 61.9% | 46.7% | |
| 42.86% | 36 | 1.1 | 768 | 12,147 | 52.6% | 31.3% | |
| 36.11% | 36 | 0.8 | 644 | 12,883 | 53.3% | 23.8% | |
| 52.94% | 35 | 3.4 | 854 | 12,606 | 35.7% | 65.0% | |
| 42.86% | 35 | 1.6 | 633 | 10,447 | 35.3% | 50.0% | |
| 52.94% | 35 | 2.8 | 796 | 12,413 | 56.3% | 50.0% | |
| 40.00% | 35 | 1.2 | 698 | 13,120 | 50.0% | 34.8% | |
| 70.97% | 31 | 1.5 | 873 | 13,865 | 91.7% | 57.9% | |
| 43.33% | 30 | 1.1 | 739 | 12,585 | 41.7% | 44.4% | |
| 50.00% | 30 | 3.8 | 836 | 10,459 | 43.8% | 57.1% | |
| 48.28% | 29 | 5.2 | 801 | 12,066 | 27.3% | 61.1% | |
| 58.62% | 29 | 5.4 | 689 | 9,868 | 65.0% | 44.4% | |
| 35.71% | 29 | 6.0 | 929 | 11,718 | 60.0% | 22.2% | |
| 39.29% | 28 | 5.3 | 736 | 12,476 | 22.2% | 47.4% | |
| 67.86% | 28 | 1.4 | 818 | 13,439 | 66.7% | 68.4% | |
| 51.85% | 27 | 4.6 | 826 | 11,525 | 52.9% | 50.0% | |
| 37.04% | 27 | 5.8 | 841 | 10,809 | 30.8% | 42.9% | |
| 50.00% | 27 | 3.2 | 728 | 11,139 | 50.0% | 50.0% | |
| 59.26% | 27 | 5.0 | 797 | 11,746 | 57.1% | 61.5% | |
| 50.00% | 26 | 5.8 | 955 | 10,630 | 66.7% | 35.7% | |
| 53.85% | 26 | 4.2 | 840 | 12,273 | 30.0% | 68.8% | |
| 38.46% | 26 | 2.1 | 741 | 11,488 | 25.0% | 50.0% | |
| 46.15% | 26 | 5.5 | 907 | 12,593 | 85.7% | 31.6% | |
| 57.69% | 26 | 5.1 | 1,010 | 12,681 | 44.4% | 64.7% | |
| 66.67% | 25 | 6.1 | 867 | 11,714 | 50.0% | 83.3% | |
| 50.00% | 24 | 1.5 | 726 | 9,839 | 66.7% | 33.3% | |
| 58.33% | 24 | 0.9 | 777 | 11,968 | 72.7% | 46.1% | |
| 52.17% | 23 | 1.4 | 683 | 9,975 | 66.7% | 42.9% | |
| 52.17% | 23 | 1.1 | 837 | 12,811 | 37.5% | 60.0% | |
| 43.48% | 23 | 4.9 | 901 | 11,003 | 36.4% | 50.0% | |
| 56.52% | 23 | 2.0 | 676 | 12,931 | 33.3% | 64.7% | |
| 54.55% | 22 | 3.6 | 904 | 12,119 | 50.0% | 58.3% | |
| 68.18% | 22 | 4.1 | 720 | 11,486 | 62.5% | 71.4% | |
| 63.64% | 22 | 1.4 | 686 | 11,692 | 53.9% | 77.8% | |
| 61.90% | 21 | 1.6 | 734 | 10,878 | 70.0% | 54.5% | |
| 47.62% | 21 | 1.5 | 803 | 13,503 | 37.5% | 53.9% | |
| 42.86% | 21 | 5.4 | 774 | 10,926 | 40.0% | 45.5% | |
| 50.00% | 20 | 5.8 | 886 | 12,224 | 44.4% | 54.5% | |
| 50.00% | 20 | 0.8 | 681 | 12,600 | 30.0% | 70.0% | |
| 45.00% | 20 | 5.5 | 1,089 | 12,540 | 42.9% | 46.1% | |
| 57.89% | 19 | 5.2 | 925 | 13,192 | 42.9% | 66.7% | |
| 57.89% | 19 | 5.4 | 850 | 11,719 | 44.4% | 70.0% | |
| 47.37% | 19 | 4.5 | 857 | 12,205 | 25.0% | 53.3% | |
| 47.37% | 19 | 3.5 | 801 | 11,970 | 37.5% | 54.5% | |
| 63.16% | 19 | 5.1 | 896 | 11,974 | 66.7% | 60.0% | |
| 66.67% | 18 | 1.8 | 836 | 11,536 | 66.7% | 66.7% | |
| 58.82% | 17 | 3.6 | 858 | 12,734 | 62.5% | 55.6% | |
| 52.94% | 17 | 1.2 | 720 | 12,966 | 75.0% | 46.1% | |
| 35.29% | 17 | 4.1 | 837 | 11,570 | 28.6% | 40.0% | |
| 52.94% | 17 | 5.4 | 945 | 10,961 | 40.0% | 71.4% | |
| 62.50% | 16 | 4.3 | 668 | 10,717 | 75.0% | 58.3% | |
| 43.75% | 16 | 4.9 | 922 | 11,712 | 16.7% | 60.0% | |
| 60.00% | 15 | 5.6 | 974 | 12,200 | 57.1% | 62.5% | |
| 33.33% | 15 | 4.8 | 709 | 10,656 | 37.5% | 28.6% | |
| 40.00% | 15 | 4.2 | 828 | 12,089 | 50.0% | 33.3% | |
| 42.86% | 15 | 0.8 | 688 | 12,198 | 28.6% | 57.1% | |
| 53.85% | 14 | 3.7 | 653 | 12,357 | 25.0% | 66.7% | |
| 42.86% | 14 | 1.4 | 646 | 11,313 | 0.0% | 54.5% | |
| 41.67% | 13 | 1.3 | 604 | 11,563 | 33.3% | 50.0% | |
| 72.73% | 11 | 5.6 | 861 | 12,756 | 60.0% | 83.3% | |
| 63.64% | 11 | 4.8 | 788 | 12,564 | 75.0% | 57.1% | |
| 60.00% | 10 | 1.4 | 694 | 12,157 | 50.0% | 66.7% | |
| 60.00% | 10 | 0.6 | 867 | 13,541 | 50.0% | 66.7% | |
| 10.00% | 10 | 3.3 | 758 | 10,367 | 0.0% | 16.7% | |
| 66.67% | 9 | 2.6 | 819 | 10,679 | 50.0% | 100.0% | |
| 75.00% | 8 | 5.1 | 913 | 13,937 | 100.0% | 66.7% | |
| 42.86% | 7 | 2.0 | 848 | 14,412 | 0.0% | 60.0% | |
| 71.43% | 7 | 4.7 | 783 | 11,782 | 75.0% | 66.7% | |
| 42.86% | 7 | 5.1 | 883 | 13,009 | 33.3% | 50.0% | |
| 66.67% | 6 | 4.0 | 832 | 12,055 | 66.7% | 66.7% | |
| 50.00% | 6 | 0.8 | 923 | 12,363 | 100.0% | 0.0% | |
| 33.33% | 6 | 2.3 | 679 | 10,133 | 33.3% | 33.3% | |
| 33.33% | 6 | 4.3 | 662 | 10,608 | 33.3% | 33.3% | |
| 33.33% | 6 | 0.9 | 932 | 12,884 | 33.3% | 33.3% | |
| 80.00% | 5 | 5.6 | 984 | 11,167 | 100.0% | 50.0% | |
| 60.00% | 5 | 3.4 | 854 | 12,460 | 100.0% | 50.0% | |
| 40.00% | 5 | 5.2 | 850 | 13,562 | 50.0% | 33.3% | |
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Pantheon vs Vayne - Frequently Asked Questions
How does Pantheon do against Vayne in League of Legends?
Pantheon wins the Pantheon vs Vayne matchup with a 53.9% win rate compared to Vayne's 46.1%, a 7.7 percentage point difference. This data is based on 26 recent ranked games in patch 26.4.
How does Pantheon do against Vayne in the early game?
In the early game, Vayne has the advantage against Pantheon with a 70.0% win rate versus 30.0%. Vayne players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Pantheon do against Vayne in the late game?
In the late game, Pantheon takes over the Pantheon vs Vayne matchup with a 68.8% win rate compared to 31.3%. Pantheon scales better into team fights and objective contests after 25 minutes.
Who wins the Pantheon vs Vayne matchup?
Pantheon wins the matchup against Vayne with a 53.9% win rate in League of Legends patch 26.4. The 7.7 percentage point advantage means Pantheon is significantly favored in this lane matchup based on 26 games analyzed.
What is the best Pantheon build against Vayne?
The best Pantheon build against Vayne includes Eclipse, Sundered Sky, Death's Dance with Ionian Boots of Lucidity. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.
What are the best Pantheon runes against Vayne?
The best Pantheon runes against Vayne use the Precision primary tree with Sorcery secondary. This rune setup achieves a 100.0% win rate in the Pantheon vs Vayne matchup. See the full rune breakdown in the matchup comparison above.
Does Pantheon counter Vayne?
Yes, Pantheon has a favorable matchup against Vayne with a 53.9% win rate. Pantheon strongly counters Vayne in lane based on current patch 26.4 data.
How do I play Pantheon against Vayne?
When playing Pantheon against Vayne, leverage your statistical advantages by trading aggressively during favorable windows. Play safe early and scale into your power spikes where you outperform Vayne. Build the recommended items and runes for this specific matchup for the best results.