
Pantheonvs Vayne
Pantheon vs Vayne is a decisive matchup in LoL patch 26.19. Pantheon wins with a 90.0% win rate (+80.0%) over Vayne based on 10 games. Pantheon holds the advantage in both the early and late game. Below you'll find the best Pantheon build, runes, laning stats, and strategies for the Pantheon vs Vayne matchup.
Pantheon Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Pantheon performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.


Who wins Pantheon vs Vayne?
Pantheon wins 72.7% of these games. With this many games the true rate is most likely between 43.4% and 90.3% (95% range).
- Expected
- 51.2% From both champions' overall Top win rates
- Matchup effect
- +21.5 pts Observed minus expected
- Sample
- 11 games Lane: Top
- vs patch 26.18
- — Not enough games on both patches
Lane: Top · Ranked Solo/Duo & Flex · North America server · All ranks · Patch 26.19 · Sep 24 – Sep 28
They also met in another lane (Bot): 3 games, Pantheon won 33.3%.
Key takeaways
- Only 11 Pantheon vs Vayne games were recorded in the Top role on patch 26.19 — too few to say who is favored. Treat the numbers below as provisional.
How we calculate this
Games: ranked Solo/Duo and Flex games on the North America server from the patch shown. Remakes (games under 5 minutes) are excluded.
A game only counts when Pantheon and Vayne played the same position on opposite teams, so roaming, lane swaps within a team or a champion merely being in the same game never count as this matchup.
The 95% range is a Wilson score interval. Confidence comes from how wide that range is: within ±3 points is very high, ±5 high, ±8 moderate, anything wider low. Below 20 games a matchup is not classified at all.
Expected win rate combines both champions’ win rates in this lane (same games and filters) with the log5 formula: E = A(1−B) / (A(1−B) + B(1−A)). Matchup effect = observed − expected.
"What changes" compares Pantheon's choices in this matchup with the same champion's other games in the same lane, and lists a change only when it is at least 3 points and statistically significant (two-proportion z-test, |z| ≥ 2, 20+ games).
Results are not split by rank: the sample per rank is too small for honest per-rank matchup numbers.
Pantheon vs Vayne Laning Stats
Only 11 games have a 15-minute snapshot so far — the lane-phase numbers appear from 30.
Whole-game averages
Pantheon vs Vayne Win Rate by Game Length
Pantheon's win rate against Vayne by game length. The dot is the win rate, the bar its 95% range and the dashed line the champion's usual win rate at that length. Lengths with fewer than 25 games are left blank.
No game length stands out: Pantheon's results against Vayne in short and long games are within the margin of error of each other.
Pantheon vs Vayne Power Spikes
Who is ahead at each stage, measured from these games. A stage reads "Even" when the difference is inside the margin of error, and "Insufficient data" when there are too few games to tell.
- Lane (15 min)Insufficient data
- First itemInsufficient data
- Games under 20 minInsufficient data
- 20–30 min gamesInsufficient data
- 30+ min gamesInsufficient data
What Pantheon Changes Against Vayne
Only 11 games so far — too few to compare what Pantheon players do in this matchup with their usual choices (needs 20).
Best Pantheon Build vs Vayne
Usual Pantheon build (Top)
78.9% win rate · 19 games
Against Vayne
Not enough matchup-specific build data: only 0 of 11 Pantheon games against Vayne carried a complete build, which is too few to recommend an item path from. Use Pantheon's standard build instead.
Builds are ranked by the lower edge of their win rate range, not the raw win rate, so a build seen in a handful of wins never outranks a proven one.
Best Pantheon Runes vs Vayne
Plan your Pantheon draft in Draft Lab
Draft Lab lays out both teams lane by lane with live matchup win rates, damage profiles and game-phase lean, and suggests picks and bans from current meta data.
- Full 5v5 draft board
- Lane matchup win rates
- Pick and ban suggestions

Pantheon matchup data for League of Legends patch 26.19. The table below shows Pantheon's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Pantheon build, runes, laning stats, and early vs late game analysis for that specific matchup.
Other Pantheon Matchups
Hardest for Pantheon
Easiest for Pantheon
Win rate and games for each matchup. Lists are ranked by the edge of the 95% range so small samples cannot top them; matchups with at least 50 games only.
Help us maintain accuracy! If you notice incorrect stats, missing data, or any issues, your feedback directly improves the quality of our data for the entire community.
Pantheon vs Vayne FAQ - Patch 26.19
Who wins Pantheon vs Vayne?
Only 11 Pantheon vs Vayne games were recorded in the Top role on patch 26.19 — too few to say who is favored. Treat the numbers below as provisional.
What is Pantheon's win rate against Vayne?
Pantheon wins 72.7% of 11 Top games against Vayne on patch 26.19 (95% range 43.4–90.3%). Based on both champions' overall Top win rates, 51.2% would be expected.
Does Pantheon counter Vayne?
There are only 11 Pantheon vs Vayne games in this lane on patch 26.19 — too few to answer reliably yet.
Who wins lane, Pantheon or Vayne?
There are not enough games with a 15-minute snapshot yet (11) to say who wins lane.
Does Pantheon outscale Vayne?
There are too few games of each length to tell yet.
When is Vayne strongest against Pantheon?
On current data there is no stage of the game where Vayne is ahead of Pantheon beyond the margin of error.
What should Pantheon build against Vayne?
There are not enough games for a matchup-specific core, so use Pantheon's usual Top core: Voltaic Cyclosword, Eclipse, Youmuu's Ghostblade.
What runes should Pantheon use against Vayne?
Use Pantheon's usual Press the Attack page (Precision + Sorcery); there are too few games for a matchup-specific page.
